Pharmacologic properties of polyethylene glycol-modified Bacillus thiaminolyticus thiaminase I enzyme

Journal of Pharmacology and Experimental Therapeutics

Volumn 341, Issue 3, 2012, Pages 775-783

  Liu, Shuqian ^a   Bae, Younsoo ^b   Leggas, Markos ^b   Daily, Abigail ^a   Bhatnagar, Saloni ^a   Miriyala, Sumitra ^a   St Clair, Daret K ^a   Moscow, Jeffrey A ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b University of Kentucky   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; COCARBOXYLASE; MACROGOL; THIAMINASE 1; THIAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BACILLUS; BACILLUS THIAMINOLYTICUS; CELL GROWTH; CELL RESPIRATION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG HALF LIFE; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; LEUKEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; TREATMENT RESPONSE; VITAMIN BLOOD LEVEL;

ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTINEOPLASTIC AGENTS; BACILLUS; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CULTURE MEDIA; FEMALE; HALF-LIFE; HUMANS; IMMUNOBLOTTING; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; OXYGEN CONSUMPTION; POLYETHYLENE GLYCOLS; THIAMINE;

EID: 84861548795     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.191817     Document Type: Article

References (11)

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