메뉴 건너뛰기




Volumn 10, Issue 11, 2010, Pages 1112-1114

Can an enzyme cofactor be a factor in malignant progression?

Author keywords

Hif1; Hypoxia; Metabolism; SLC19A3; Thiamine; THTR2; Vitamin B1

Indexed keywords

ACETYL COENZYME A; CARRIER PROTEIN; ENZYME; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; OXOGLUTARATE DEHYDROGENASE; PROTEIN KINASE B; PROTEIN SLC19A3; PYRUVATE DEHYDROGENASE; THIAMINE; TRANSKETOLASE; UNCLASSIFIED DRUG;

EID: 78649836690     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.10.11.14061     Document Type: Note
Times cited : (10)

References (20)
  • 1
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009; 324:1029-33.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 2
    • 0036085901 scopus 로고    scopus 로고
    • Reduced folate carrier transports thiamine monophosphate: An alternative route for thiamine delivery into mammalian cells
    • Zhao R, Gao F, Goldman ID. Reduced folate carrier transports thiamine monophosphate: an alternative route for thiamine delivery into mammalian cells. Am J Physiol Cell Physiol 2002; 282:1512-7.
    • (2002) Am J Physiol Cell Physiol , vol.282 , pp. 1512-1517
    • Zhao, R.1    Gao, F.2    Goldman, I.D.3
  • 3
    • 0035846930 scopus 로고    scopus 로고
    • Impact of the reduced folate carrier on the accumulation of active thiamin metabolites in murine leukemia cells
    • Zhao R, Gao F, Wang Y, Diaz GA, Gelb BD, Goldman ID. Impact of the reduced folate carrier on the accumulation of active thiamin metabolites in murine leukemia cells. J Biol Chem 2001; 276:1114-8.
    • (2001) J Biol Chem , vol.276 , pp. 1114-1118
    • Zhao, R.1    Gao, F.2    Wang, Y.3    Diaz, G.A.4    Gelb, B.D.5    Goldman, I.D.6
  • 4
    • 0028969669 scopus 로고
    • Thiamine homeostasis in neuroblastoma cells
    • Bettendorff L. Thiamine homeostasis in neuroblastoma cells. Neurochem Int 1995; 26:295-302.
    • (1995) Neurochem Int , vol.26 , pp. 295-302
    • Bettendorff, L.1
  • 5
    • 0030766181 scopus 로고    scopus 로고
    • Reversibility of thiamine deficiency-induced partial necrosis and mitochondrialuncoupling by addition of thiamine to neuroblastoma cell suspensions
    • Bettendorff L, Goessens G, Sluse F. Reversibility of thiamine deficiency-induced partial necrosis and mitochondrialuncoupling by addition of thiamine to neuroblastoma cell suspensions. Mol Cell Biochem 1997; 174:121-4.
    • (1997) Mol Cell Biochem , vol.174 , pp. 121-124
    • Bettendorff, L.1    Goessens, G.2    Sluse, F.3
  • 6
    • 0028934399 scopus 로고
    • Thiamine deficiency in cultured neuroblastoma cells: Effect on mitochondrial function and peripheral benzodiazepine receptors
    • Bettendorff L, Goessens G, Sluse F, Wins P, Bureau M, Laschet J, et al. Thiamine deficiency in cultured neuroblastoma cells: effect on mitochondrial function and peripheral benzodiazepine receptors. J Neurochem 1995; 64:2013-21.
    • (1995) J Neurochem , vol.64 , pp. 2013-2021
    • Bettendorff, L.1    Goessens, G.2    Sluse, F.3    Wins, P.4    Bureau, M.5    Laschet, J.6
  • 8
    • 0024382089 scopus 로고
    • Thiamine triphosphatase in the membranes of the main electric organ of Electrophorus electricus: Substrate-enzyme interactions
    • Bettendorff L, Grandfils C, Wins P, Schoffeniels E. Thiamine triphosphatase in the membranes of the main electric organ of Electrophorus electricus: substrate-enzyme interactions. J Neurochem 1989; 53:738-46.
    • (1989) J Neurochem , vol.53 , pp. 738-746
    • Bettendorff, L.1    Grandfils, C.2    Wins, P.3    Schoffeniels, E.4
  • 9
    • 0028334654 scopus 로고
    • Mechanism of thiamine transport in neuroblastoma cells
    • Bettendorff L, Wins P. Mechanism of thiamine transport in neuroblastoma cells. J Biol Chem 1994; 269:14379-85.
    • (1994) J Biol Chem , vol.269 , pp. 14379-14385
    • Bettendorff, L.1    Wins, P.2
  • 10
    • 78649859188 scopus 로고    scopus 로고
    • Hypoxia Induced Upregulation and Function of the Thiamine Transporter, SLC19A3 in a Breast Cancer Cell Line
    • Sweet R, Paul A, Zastre J. Hypoxia Induced Upregulation and Function of the Thiamine Transporter, SLC19A3 in a Breast Cancer Cell Line. Cancer Biol Ther 2010; 1101-11.
    • (2010) Cancer Biol Ther , pp. 1101-1111
    • Sweet, R.1    Paul, A.2    Zastre, J.3
  • 11
    • 0012595471 scopus 로고    scopus 로고
    • Downregulation of thiamine transporter THTR2 gene expression in breast cancer and its association with resistance to apoptosis
    • Liu S, Huang H, Lu X, Golinski M, Comesse S, Watt D, et al. Downregulation of thiamine transporter THTR2 gene expression in breast cancer and its association with resistance to apoptosis. Mol Cancer Res 2003; 1:665-73.
    • (2003) Mol Cancer Res , vol.1 , pp. 665-673
    • Liu, S.1    Huang, H.2    Lu, X.3    Golinski, M.4    Comesse, S.5    Watt, D.6
  • 12
    • 4344702050 scopus 로고    scopus 로고
    • Thiamine transporter gene expression and exogenous thiamine modulate the expression of genes involved in drug and prostaglandin metabolism in breast cancer cells
    • Liu S, Stromberg A, Tai HH, Moscow JA. Thiamine transporter gene expression and exogenous thiamine modulate the expression of genes involved in drug and prostaglandin metabolism in breast cancer cells. Mol Cancer Res 2004; 2:477-87.
    • (2004) Mol Cancer Res , vol.2 , pp. 477-487
    • Liu, S.1    Stromberg, A.2    Tai, H.H.3    Moscow, J.A.4
  • 13
    • 33644614520 scopus 로고    scopus 로고
    • HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
    • Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 2006; 3:177-85.
    • (2006) Cell Metab , vol.3 , pp. 177-185
    • Kim, J.W.1    Tchernyshyov, I.2    Semenza, G.L.3    Dang, C.V.4
  • 14
    • 0345491599 scopus 로고    scopus 로고
    • Differential Roles of Hypoxia-Inducible Factor 1alpha (HIF-1alpha) and HIF-2alpha in Hypoxic Gene Regulation
    • DOI 10.1128/MCB.23.24.9361-9374.2003
    • Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC. Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol Cell Biol 2003; 23:9361-74. (Pubitemid 37499822)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.24 , pp. 9361-9374
    • Hu, C.-J.1    Wang, L.-Y.2    Chodosh, L.A.3    Keith, B.4    Simon, M.C.5
  • 15
    • 33344456073 scopus 로고    scopus 로고
    • Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted
    • Langbein S, Zerilli M, Zur Hausen A, Staiger W, Rensch-Boschert K, Lukan N, et al. Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted. Br J Cancer 2006; 94:578-85.
    • (2006) Br J Cancer , vol.94 , pp. 578-585
    • Langbein, S.1    Zerilli, M.2    Zur Hausen, A.3    Staiger, W.4    Rensch-Boschert, K.5    Lukan, N.6
  • 16
    • 33846807764 scopus 로고    scopus 로고
    • Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases
    • Krockenberger M, Honig A, Rieger L, Coy JF, Sutterlin M, Kapp M, et al. Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases. Int J Gynecol Cancer 2007; 17:101-6.
    • (2007) Int J Gynecol Cancer , vol.17 , pp. 101-106
    • Krockenberger, M.1    Honig, A.2    Rieger, L.3    Coy, J.F.4    Sutterlin, M.5    Kapp, M.6
  • 18
    • 33645467294 scopus 로고    scopus 로고
    • Differential protein expression in brain capillary endothelial cells induced by hypoxia and posthypoxic reoxygenation
    • Haseloff RF, Krause E, Bigl M, Mikoteit K, Stanimirovic D, Blasig IE. Differential protein expression in brain capillary endothelial cells induced by hypoxia and posthypoxic reoxygenation. Proteomics 2006; 6:1803-9.
    • (2006) Proteomics , vol.6 , pp. 1803-1809
    • Haseloff, R.F.1    Krause, E.2    Bigl, M.3    Mikoteit, K.4    Stanimirovic, D.5    Blasig, I.E.6
  • 19
    • 76049104247 scopus 로고    scopus 로고
    • TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization
    • Sun W, Liu Y, Glazer CA, Shao C, Bhan S, Demokan S, et al. TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization. Clin Cancer Res 16:857-66.
    • Clin Cancer Res , vol.16 , pp. 857-866
    • Sun, W.1    Liu, Y.2    Glazer, C.A.3    Shao, C.4    Bhan, S.5    Demokan, S.6
  • 20
    • 77952673654 scopus 로고    scopus 로고
    • Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming
    • Zhao F, Mancuso A, Bui TV, Tong X, Gruber JJ, Swider CR, et al. Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming. Oncogene 29:2962-72.
    • Oncogene , vol.29 , pp. 2962-2972
    • Zhao, F.1    Mancuso, A.2    Bui, T.V.3    Tong, X.4    Gruber, J.J.5    Swider, C.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.