-
1
-
-
77649337790
-
Hedgehog beyond medulloblastoma and basal cell carcinoma
-
Biochim Biophys Acta 1805, 181-208
-
Teglund S, Toftgård R, (2010) Hedgehog beyond medulloblastoma and basal cell carcinoma. Biochim Biophys Acta 1805 181-208 pp. 181-208.
-
(2010)
, pp. 181-208
-
-
Teglund, S.1
Toftgård, R.2
-
2
-
-
56849116719
-
Role and regulation of human tumor suppressor SUFU in Hedgehog signaling
-
Cheng SY, Yue S, (2008) Role and regulation of human tumor suppressor SUFU in Hedgehog signaling. Adv Cancer Res 101: 29-43.
-
(2008)
Adv Cancer Res
, vol.101
, pp. 29-43
-
-
Cheng, S.Y.1
Yue, S.2
-
3
-
-
0033194243
-
Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1
-
Kogerman P, Grimm T, Kogerman L, Krause D, Unden AB, et al. (1999) Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1. Nat Cell Biol 1: 312-319.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 312-319
-
-
Kogerman, P.1
Grimm, T.2
Kogerman, L.3
Krause, D.4
Unden, A.B.5
-
4
-
-
77950463564
-
The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
-
Humke EW, Dorn KV, Milenkovic L, Scott MP, Rohatgi R, (2010) The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins. Genes Dev 24: 670-682.
-
(2010)
Genes Dev
, vol.24
, pp. 670-682
-
-
Humke, E.W.1
Dorn, K.V.2
Milenkovic, L.3
Scott, M.P.4
Rohatgi, R.5
-
5
-
-
77953050811
-
Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors
-
Wang C, Pan Y, Wang B, (2010) Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors. Development 137: 2001-2009.
-
(2010)
Development
, vol.137
, pp. 2001-2009
-
-
Wang, C.1
Pan, Y.2
Wang, B.3
-
6
-
-
77958508124
-
A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes
-
Tukachinsky H, Lopez LV, Salic A, (2010) A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes. J Cell Biol 191: 415-428.
-
(2010)
J Cell Biol
, vol.191
, pp. 415-428
-
-
Tukachinsky, H.1
Lopez, L.V.2
Salic, A.3
-
7
-
-
59149087474
-
Hedgehog signaling promotes the degradation of tumor suppressor Sufu through the ubiquitin-proteasome pathway
-
Yue S, Chen Y, Cheng SY, (2009) Hedgehog signaling promotes the degradation of tumor suppressor Sufu through the ubiquitin-proteasome pathway. Oncogene 28: 492-499.
-
(2009)
Oncogene
, vol.28
, pp. 492-499
-
-
Yue, S.1
Chen, Y.2
Cheng, S.Y.3
-
8
-
-
31744451535
-
Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
-
Svärd J, Heby-Henricson K, Persson-Lek M, Rozell B, Lauth M, et al. (2006) Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway. Dev Cell 10: 187-197.
-
(2006)
Dev Cell
, vol.10
, pp. 187-197
-
-
Svärd, J.1
Heby-Henricson, K.2
Persson-Lek, M.3
Rozell, B.4
Lauth, M.5
-
9
-
-
0036648241
-
Mutations in SUFU predispose to medulloblastoma
-
Taylor MD, Liu L, Raffel C, Hui CC, Mainprize TG, et al. (2002) Mutations in SUFU predispose to medulloblastoma. Nat Genet 31: 306-310.
-
(2002)
Nat Genet
, vol.31
, pp. 306-310
-
-
Taylor, M.D.1
Liu, L.2
Raffel, C.3
Hui, C.C.4
Mainprize, T.G.5
-
10
-
-
13644261744
-
Activation of the hedgehog pathway in advanced prostate cancer
-
Sheng T, Li C, Zhang X, Chi S, He N, et al. (2004) Activation of the hedgehog pathway in advanced prostate cancer. Mol Cancer 3: 29.
-
(2004)
Mol Cancer
, vol.3
, pp. 29
-
-
Sheng, T.1
Li, C.2
Zhang, X.3
Chi, S.4
He, N.5
-
11
-
-
29744463531
-
Deregulation of the hedgehog signalling pathway: a possible role for the PTCH and SUFU genes in human rhabdomyoma and rhabdomyosarcoma development
-
Tostar U, Malm CJ, Meis-Kindblom JM, Kindblom LG, Toftgard R, et al. (2006) Deregulation of the hedgehog signalling pathway: a possible role for the PTCH and SUFU genes in human rhabdomyoma and rhabdomyosarcoma development. J Pathol 208: 17-25.
-
(2006)
J Pathol
, vol.208
, pp. 17-25
-
-
Tostar, U.1
Malm, C.J.2
Meis-Kindblom, J.M.3
Kindblom, L.G.4
Toftgard, R.5
-
12
-
-
0035823106
-
Genomic organization and embryonic expression of Suppressor of Fused, a candidate gene for the split-hand/split-foot malformation type 3
-
Grimm T, Teglund S, Tackels D, Sangiorgi E, Gurrieri F, et al. (2001) Genomic organization and embryonic expression of Suppressor of Fused, a candidate gene for the split-hand/split-foot malformation type 3. FEBS Lett 505: 13-17.
-
(2001)
FEBS Lett
, vol.505
, pp. 13-17
-
-
Grimm, T.1
Teglund, S.2
Tackels, D.3
Sangiorgi, E.4
Gurrieri, F.5
-
13
-
-
0033491071
-
Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
-
Stone DM, Murone M, Luoh S, Ye W, Armanini MP, et al. (1999) Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. J Cell Sci 112 (Pt 23): 4437-4448.
-
(1999)
J Cell Sci
, vol.112
, Issue.Pt 23
, pp. 4437-4448
-
-
Stone, D.M.1
Murone, M.2
Luoh, S.3
Ye, W.4
Armanini, M.P.5
-
14
-
-
9644264182
-
Nevoid basal cell carcinoma (Gorlin) syndrome
-
Gorlin RJ, (2004) Nevoid basal cell carcinoma (Gorlin) syndrome. Genet Med 6: 530-539.
-
(2004)
Genet Med
, vol.6
, pp. 530-539
-
-
Gorlin, R.J.1
-
15
-
-
0036317926
-
Characterisation of the BRCT domains of the breast cancer susceptibility gene product BRCA1
-
Ekblad CM, Wilkinson HR, Schymkowitz JW, Rousseau F, Freund SM, et al. (2002) Characterisation of the BRCT domains of the breast cancer susceptibility gene product BRCA1. J Mol Biol 320: 431-442.
-
(2002)
J Mol Biol
, vol.320
, pp. 431-442
-
-
Ekblad, C.M.1
Wilkinson, H.R.2
Schymkowitz, J.W.3
Rousseau, F.4
Freund, S.M.5
-
16
-
-
4544353067
-
Suppressor of fused regulates Gli activity through a dual binding mechanism
-
Merchant M, Vajdos FF, Ultsch M, Maun HR, Wendt U, et al. (2004) Suppressor of fused regulates Gli activity through a dual binding mechanism. Mol Cell Biol 24: 8627-8641.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8627-8641
-
-
Merchant, M.1
Vajdos, F.F.2
Ultsch, M.3
Maun, H.R.4
Wendt, U.5
-
17
-
-
0038813753
-
Characterization of the physical interaction of Gli proteins with SUFU proteins
-
Dunaeva M, Michelson P, Kogerman P, Toftgard R, (2003) Characterization of the physical interaction of Gli proteins with SUFU proteins. J Biol Chem 278: 5116-5122.
-
(2003)
J Biol Chem
, vol.278
, pp. 5116-5122
-
-
Dunaeva, M.1
Michelson, P.2
Kogerman, P.3
Toftgard, R.4
-
18
-
-
47249159395
-
Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal
-
Shimokawa T, Tostar U, Lauth M, Palaniswamy R, Kasper M, et al. (2008) Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal. J Biol Chem 283: 14345-14354.
-
(2008)
J Biol Chem
, vol.283
, pp. 14345-14354
-
-
Shimokawa, T.1
Tostar, U.2
Lauth, M.3
Palaniswamy, R.4
Kasper, M.5
-
19
-
-
0033533714
-
Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1
-
Ding Q, Fukami S, Meng X, Nishizaki Y, Zhang X, et al. (1999) Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr Biol 9: 1119-1122.
-
(1999)
Curr Biol
, vol.9
, pp. 1119-1122
-
-
Ding, Q.1
Fukami, S.2
Meng, X.3
Nishizaki, Y.4
Zhang, X.5
-
20
-
-
31744450041
-
Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms
-
Barnfield PC, Zhang X, Thanabalasingham V, Yoshida M, Hui CC, (2005) Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms. Differentiation 73: 397-405.
-
(2005)
Differentiation
, vol.73
, pp. 397-405
-
-
Barnfield, P.C.1
Zhang, X.2
Thanabalasingham, V.3
Yoshida, M.4
Hui, C.C.5
-
21
-
-
9644253204
-
A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions
-
Shimokawa T, Rahnama F, Zaphiropoulos PG, (2004) A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions. FEBS Lett 578: 157-162.
-
(2004)
FEBS Lett
, vol.578
, pp. 157-162
-
-
Shimokawa, T.1
Rahnama, F.2
Zaphiropoulos, P.G.3
-
22
-
-
34547478739
-
Distinct roles of first exon variants of the tumor-suppressor Patched1 in Hedgehog signaling
-
Shimokawa T, Svärd J, Heby-Henricson K, Teglund S, Toftgård R, et al. (2007) Distinct roles of first exon variants of the tumor-suppressor Patched1 in Hedgehog signaling. Oncogene 26: 4889-4896.
-
(2007)
Oncogene
, vol.26
, pp. 4889-4896
-
-
Shimokawa, T.1
Svärd, J.2
Heby-Henricson, K.3
Teglund, S.4
Toftgård, R.5
-
23
-
-
77955172368
-
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
-
Gao C, Cao W, Bao L, Zuo W, Xie G, et al. (2010) Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation. Nat Cell Biol 12: 781-790.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 781-790
-
-
Gao, C.1
Cao, W.2
Bao, L.3
Zuo, W.4
Xie, G.5
-
24
-
-
79952820588
-
Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway
-
Tostar U, Toftgård R, Zaphiropoulos PG, Shimokawa T, (2010) Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway. Genes & Cancer 1: 941-951.
-
(2010)
Genes & Cancer
, vol.1
, pp. 941-951
-
-
Tostar, U.1
Toftgård, R.2
Zaphiropoulos, P.G.3
Shimokawa, T.4
|