Bioactive hydrogels demonstrate mediated release of a chromophore by chymotrypsin

Journal of Controlled Release

Volumn 160, Issue 1, 2012, Pages 41-47

  Wilson, A Nolan ^a,b   Salas, Ruth ^a,b   Guiseppi Elie, Anthony ^a,b,c  

^a CLEMSON UNIVERSITY   (United States)

^b Clemson University   (United States)

^c ABTECH Scientific Inc   (United States)

Author keywords

Enzyme cleavage; Mediated release; p(HEMA); p Nitroanilide; Responsive hydrogel; Thiele modulus

Indexed keywords

AMINO GROUP; BIOACTIVE HYDROGELS; CARBOXYL GROUPS; DELIVERY SYSTEMS; ENZYMATIC CLEAVAGE; MEDIATED RELEASE; MODEL SYSTEM; P-NITROANILIDE; PRIMARY AMINES; RELEASE RATE; SUBSTRATE LOADING; THIELE MODULUS;

CHROMOPHORES; ENZYMES; LOADING; PEPTIDES;

HYDROGELS;

2,2 DIMETHOXY 2 PHENYLACETOPHENONE; ACETOPHENONE DERIVATIVE; ACRYLAMIDE DERIVATIVE; ACRYLIC ACID DERIVATIVE; AMINO ACID; CHYMOTRYPSIN; METHACRYLIC ACID 2 AMINOETHYL ESTER; N [TRIS(HYDROXYMETHYL)METHYL]ACRYLAMIDE; POLYMACON; TETRAETHYLENEGLYCOL DIACRYLATE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CHROMATOPHORE; HYDROGEL; PRIORITY JOURNAL;

CHROMOGENIC COMPOUNDS; CHYMOTRYPSIN; CROSS-LINKING REAGENTS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HYDROGELS; METHACRYLATES; MODELS, CHEMICAL; MOLECULAR STRUCTURE; OLIGOPEPTIDES; SUBSTRATE SPECIFICITY;

EID: 84861529615     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.02.026     Document Type: Article

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