Spray-dried Cefixime Encapsulated Poly(lactide-co-glycolide) Microparticles: Characterization and Evaluation of In Vitro Release Kinetics with Antibacterial Activity

Drying Technology

Volumn 30, Issue 8, 2012, Pages 865-872

  Raval, Jignesh P ^a   Naik, Deep R ^a   Patel, Pradip S ^a  

^a Ashok & Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences   (India)

Author keywords

Antibacterial activity; Cefixime; Controlled delivery; Encapsulation; Microparticles; PLGA; Spray drying technique

Indexed keywords

ANTI-BACTERIAL ACTIVITY; CEFIXIME; CONTROLLED DELIVERY; MICRO-PARTICLES; PLGA; SPRAY DRYING TECHNIQUE;

DISSOLUTION; ENCAPSULATION; MICROORGANISMS; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; X RAY DIFFRACTION;

CONTROLLED DRUG DELIVERY;

EID: 84861518913     PISSN: 07373937     EISSN: 15322300     Source Type: Journal    
DOI: 10.1080/07373937.2012.673526     Document Type: Article

References (29)

1. Raffin, R.P.; Guterres, S.S.; Pohlmann, A.R.; Re, M.I. Powder characteristics of pantoprazole delivery systems produced in different spray-dryer scales. Drying Technology 2006, 24, 339-348.
2. Choudhury, P.K.; Kar, M. Controlled release metformin hydrochloride microspheres of ethyl cellulose prepared by different methods and study on the polymer affected parameters. Journal of Microencapsulation 2009, 26, 46-53.
3. Zhang, J.X.; Zhu, K.J.; Chen, D. Preparation of bovine serum albumin loaded poly (D,L-lactic-co-glycolic acid) microspheres by a modified phase separation technique. Journal of Microencapsulation 2005, 22, 117-126.
4. Liu, C.; Desai, K.G.H.; Tang, X.; Chen, X. Drug release kinetics of spray-dried chitosan microspheres. Drying Technology 2006, 24, 769-776.
5. Jeong, W.J.; Kim, J.Y.; Choo, J.; Lee, E.K.; Han, C.S.; Beebe, D.J.; Seong, G.H.; Lee, S.H. Continuous fabrication of biocatalyst immobilized microparticles using photopolymerization and immiscible liquids in microfluidic systems. Langmuir 2005, 21, 3738-3741.
6. Re, M.I. Formulating drug delivery systems by spray drying. Drying Technology 2006, 24, 433-446.
7. Mujumdar, A.S. Research and developments in drying: Recent trends and future prospectus. Drying Technology 2004, 22, 1-26.
8. Birchal, V.S.; Passos, M.L.; Wildhagen, G.R.S.; Mujumdar, A.S. Effect of spray-dryer operating variables on the whole milk powder quality. Drying Technology 2005, 23, 611-636.
9. Huang, L.; Kumar, K.; Mujumdar, A.S. A parametric study of the gas flow patterns and drying performance of co-current spray dryer: Results of a computational fluid dynamics study. Drying Technology 2003, 22, 957-978.
10. Desai, K.G.H.; Park, H.J. Recent developments in microencapsulation of food ingredients. Drying Technology 2005, 23, 1361-1394.
11. Marreto, R.N.; Freire, J.T.; Freitas, L.A.P. Drying of pharmaceuticals: The applicability of spouted beds. Drying Technology 2006, 24, 327-338.
12. Riveros, B.; Ferrer, J.; Borquez, R. Spray drying of a vaginal probiotic strain of Lactobacillus acidophilus. Drying Technology 2009, 27, 123-132.
13. Jafari, S.M.; Assadpoor, E.; He, Y.; Bhandari, B. Encapsulation efficiency of food flavours and oils during spray drying. Drying Technology 2008, 26, 816-835.
14. Goula, A.M.; Adamopoulos, K.G. Effect of maltodextrin addition during spray drying of tomato pulp in dehumidified air: I. Drying kinetics and product recovery. Drying Technology 2008, 26, 714-725.
15. Ameri, M.; Maa, Y.F. Spray drying of biopharmaceuticals: Stability and process considerations. Drying Technology 2006, 24 (6), 763-768.
16. Oliveira, B.F.; Santana, M.H.A.; Re, M.I. Spray-dried chitosan microspheres as a pDNA carrier. Drying Technology 2006, 24, 373-382.
17. Huynh, T.V.; Caffin, N.; Dykes, G.A.; Bhandari, B. Optimization of the microencapsulation of lemon myrtle oil using response surface methodology. Drying Technology 2008, 26, 357-368.
18. Liu, C.S.; Desai, K.G.H.; Meng, X.H.; Chen, X.G. Sweet potato starch microparticles as controlled drug release carriers: Preparation and in vitro drug release. Drying Technology 2007, 25, 689-693.
19. Panyam, J.; Labhasetwar, V. Targeting intracellular targets. Current Drug Delivery 2004, 1, 235-247.
20. Mundargi, R.C.; Babu, V.R.; Rangaswamy, V.; Patel, P.; Aminabhavi, T.M. Nano/micro technologies for delivering macromolecular therapeutics using poly(D,L-lactide-co-glycolide) and its derivatives. Journal of Control Release 2008, 125, 193-209.
21. Bala, I.; Hariharan, S.; Kumar, M.N. PLGA nanoparticles in drug delivery: The state of the art. Crit. Rev. Therapeutic Drug Carrier System 2004, 21, 387-422.
22. Park, J.H.; Ye, M.; Park, K. Biodegradable polymers for microencapsulation of drugs. Molecules 2005, 10, 146-161.
23. Quintiliani, R. Cefixime in the treatment of patients with lower respiratory tract infections: Results of US clinical trials. Clinical Therapeutics 1996, 18, 373-390.
24. Raosaheb, N.S.; Narayan, B.A. Development and evaluation of once a day oral controlled multiparticulate drug delivery systems of cefixime trihydrate. Indian Journal of Pharmaceutical Education Research 2008, 42, 283-294.
25. Braga, G.K.; Oliveira, W.P. Manufacturing drug loaded chitosan microspheres by spray drying: Development, characterization, and potential use in dentistry. Drying Technology 2007, 25, 303-310.
26. Chiou, S.H.; Wu, W.T.; Huang, Y.Y.; Chung, T.W. Effect of the characteristics of chitosan on controlling drug release of chitosan coated PLLA microspheres. Journal of Microencapsulation 2001, 18, 613-625.
27. Higuchi, T. Mechanism of sustained-action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. Journal of Pharmaceutical Science 1963, 52, 1145-1149.
28. Korsmeyer, R.W.; Gurny, R.; Doelker, E.M.; Buri, P.; Peppas, N.A. Mechanism of solute release from porous hydrophilic polymers. International Journal of Pharmaceutics 1983, 15, 25-35.
29. Magit, A.E.; Dolitsky, J.N.; Doyle, W.J.; Swarts, J.D.; Seroky, J.T.; Rosenfeld, R.M. An experimental study of cefixime in the treatment of Streptococcus pneumoniae otitis media. International Journal of Pediatrics Otorhi 1994, 29, 1-9.