Synthesis and biological evaluation of new ligustrazine derivatives as anti-tumor agents

Molecules

Volumn 17, Issue 5, 2012, Pages 4972-4985

  Wang, Penglong ^a   She, Gaimei ^a   Yang, Yanan ^b   Li, Qiang ^a   Zhang, Honggui ^a   Liu, Jie ^a   Cao, Yinqiu ^a   Xu, Xin ^a   Lei, Haimin ^a  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Angiogenesis; Anti tumor; Combination principles; Ligustrazine derivatives; Low toxicity

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; HERBACEOUS AGENT; PYRAZINE DERIVATIVE; TETRAMETHYLPYRAZINE;

ANGIOGENESIS; ANIMAL; ARTICLE; CELL SURVIVAL; CHEMISTRY; CHICK EMBRYO; CHORIOALLANTOIS; DRUG DEVELOPMENT; DRUG EFFECT; FEMALE; HUMAN; LD 50; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS; TUMOR CELL LINE; VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL SURVIVAL; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; DRUG DISCOVERY; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; LETHAL DOSE 50; MAGNETIC RESONANCE SPECTROSCOPY; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; PYRAZINES;

EID: 84861504545     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17054972     Document Type: Article

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