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Volumn 77, Issue 4, 2012, Pages 275-282

Reduction of uric acid levels with allopurinol treatment improves endothelial function in patients with chronic kidney disease

Author keywords

Allopurinol; Chronic kidney disease; Endothelial dysfunction; Oxidative stress; Uric acid

Indexed keywords

3 NITROTYROSINE; ADVANCED OXIDATION PROTEIN PRODUCT; ALBUMIN; ALLOPURINOL; C REACTIVE PROTEIN; CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXIDIZED LOW DENSITY LIPOPROTEIN; REACTIVE OXYGEN METABOLITE; TRIACYLGLYCEROL; URIC ACID; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 84861502810     PISSN: 03010430     EISSN: None     Source Type: Journal    
DOI: 10.5414/CN107352     Document Type: Article
Times cited : (58)

References (51)
  • 1
    • 0032229826 scopus 로고    scopus 로고
    • Epidemiology of cardiovascular disease in chronic renal disease
    • PubMed
    • Foley RN, Parfrey PS, Sarnak MJ. Epidemiology of cardiovascular disease in chronic renal disease. J Am Soc Nephrol. 1998; 9 (Suppl): S16-S23. PubMed
    • (1998) J Am Soc Nephrol. , vol.9 , Issue.SUPPL.
    • Foley, R.N.1    Parfrey, P.S.2    Sarnak, M.J.3
  • 2
    • 0034622282 scopus 로고    scopus 로고
    • Premature cardiovascular disease in chronic renal failure
    • doi:10.1016/S0140-67 36(00)02456-9 PubMed
    • Baigent C, Burbury K, Wheeler D. Premature cardiovascular disease in chronic renal failure. Lancet. 2000; 356: 147-152. doi:10.1016/S0140-67 36(00)02456-9 PubMed
    • (2000) Lancet. , vol.356 , pp. 147-152
    • Baigent, C.1    Burbury, K.2    Wheeler, D.3
  • 3
    • 0141620215 scopus 로고    scopus 로고
    • A population-based study of the incidence and outcomes of diagnosed chronic kidney disease
    • doi:10.1016/S0 272-6386(03)00916-8 PubMed
    • Drey N, Roderick P, Mullee M, Rogerson M. A population-based study of the incidence and outcomes of diagnosed chronic kidney disease. Am J Kidney Dis. 2003; 42: 677-684. doi:10.1016/S0 272-6386(03)00916-8 PubMed
    • (2003) Am J Kidney Dis. , vol.42 , pp. 677-684
    • Drey, N.1    Roderick, P.2    Mullee, M.3    Rogerson, M.4
  • 4
    • 0036379472 scopus 로고    scopus 로고
    • Mild renal insufficiency is associated with increased cardiovascular mortality: The Hoorn Study
    • doi:10.1111/j.1523-1755.2002.kid571.x PubMed
    • Henry RM, Kostense PJ, Bos G, Dekker JM, Nijpels G, Heine RJ, Bouter LM, Stehouwer CD. Mild renal insufficiency is associated with increased cardiovascular mortality: The Hoorn Study. Kidney Int. 2002; 62: 1402-1407. doi:10.1111/j.1523-1755.2002.kid571.x PubMed
    • (2002) Kidney Int. , vol.62 , pp. 1402-1407
    • Henry, R.M.1    Kostense, P.J.2    Bos, G.3    Dekker, J.M.4    Nijpels, G.5    Heine, R.J.6    Bouter, L.M.7    Stehouwer, C.D.8
  • 5
    • 12244269700 scopus 로고    scopus 로고
    • Level of kidney function as a risk factor for cardiovascular outcomes in the elderly
    • doi:10.1046/j.1523-1755. 2 003.00838.x PubMed
    • Manjunath G, Tighiouart H, Coresh J, Macleod B, Salem DN, Griffith JL, Levey AS, Sarnak MJ. Level of kidney function as a risk factor for cardiovascular outcomes in the elderly. Kidney Int. 2003; 63: 1121-1129. doi:10.1046/j.1523-1755. 2 003.00838.x PubMed
    • (2003) Kidney Int. , vol.63 , pp. 1121-1129
    • Manjunath, G.1    Tighiouart, H.2    Coresh, J.3    Macleod, B.4    Salem, D.N.5    Griffith, J.L.6    Levey, A.S.7    Sarnak, M.J.8
  • 6
    • 0036190001 scopus 로고    scopus 로고
    • Renal insufficiency and subsequent death resulting from cardiovascular disease in the United States
    • PubMed
    • Muntner P, He J, Hamm L, Loria C, Whelton PK. Renal insufficiency and subsequent death resulting from cardiovascular disease in the United States. J Am Soc Nephrol. 2002; 13: 745-753. PubMed
    • (2002) J Am Soc Nephrol. , vol.13 , pp. 745-753
    • Muntner, P.1    He, J.2    Hamm, L.3    Loria, C.4    Whelton, P.K.5
  • 7
    • 20844434983 scopus 로고    scopus 로고
    • Chronic kidney disease as cause of cardiovascular morbidity and mortality
    • European Uremic Toxin Work Group
    • Vanholder R, Massy Z, Argiles A, Spasovski G, Verbeke F, Lameire N; European Uremic Toxin Work Group. Chronic kidney disease as cause of cardiovascular morbidity and mortality. Nephrol Dial Transplant. 2005; 20: 1048-1056. doi:10. 10 93/ndt/gfh813 PubMed
    • (2005) Nephrol Dial Transplant. , vol.20 , pp. 1048-1056
    • Vanholder, R.1    Massy, Z.2    Argiles, A.3    Spasovski, G.4    Verbeke, F.5    Lameire, N.6
  • 9
    • 16844376116 scopus 로고    scopus 로고
    • Traditional and nontraditional risk factors predict coronary heart disease in chronic kidney disease: results from the atherosclerosis risk in communities study
    • doi:10.1681/ASN.2004080656 PubMed
    • Muntner P, He J, Astor BC, Folsom AR, Coresh J. Traditional and nontraditional risk factors predict coronary heart disease in chronic kidney disease: results from the atherosclerosis risk in communities study. J Am Soc Nephrol. 2005; 16: 529-538. doi:10.1681/ASN.2004080656 PubMed
    • (2005) J Am Soc Nephrol. , vol.16 , pp. 529-538
    • Muntner, P.1    He, J.2    Astor, B.C.3    Folsom, A.R.4    Coresh, J.5
  • 10
    • 0036833743 scopus 로고    scopus 로고
    • The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia
    • doi:10. 1046/j.1523-1755.2002.00600.x PubMed
    • Himmelfarb J, Stenvinkel P, Ikizler TA, Hakim RM. The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia. Kidney Int. 2002; 62: 1524-1538. doi:10. 1046/j.1523-1755.2002.00600.x PubMed
    • (2002) Kidney Int. , vol.62 , pp. 1524-1538
    • Himmelfarb, J.1    Stenvinkel, P.2    Ikizler, T.A.3    Hakim, R.M.4
  • 12
    • 0034097204 scopus 로고    scopus 로고
    • Renal transplant-associated hyperuricemia and gout
    • PubMed
    • Clive DM. Renal transplant-associated hyperuricemia and gout. J Am Soc Nephrol. 2000; 11: 974-979. PubMed
    • (2000) J Am Soc Nephrol. , vol.11 , pp. 974-979
    • Clive, D.M.1
  • 14
    • 0028894013 scopus 로고
    • Natural history and etiology of hyperuricemia following pediatric renal transplantation
    • doi:10.1007/BF00858973 PubMed
    • Edvardsson VO, Kaiser BA, Polinsky MS, Palmer JA, Quien R, Baluarte HJ. Natural history and etiology of hyperuricemia following pediatric renal transplantation. Pediatr Nephrol. 1995; 9: 57-60. doi:10.1007/BF00858973 PubMed
    • (1995) Pediatr Nephrol. , vol.9 , pp. 57-60
    • Edvardsson, V.O.1    Kaiser, B.A.2    Polinsky, M.S.3    Palmer, J.A.4    Quien, R.5    Baluarte, H.J.6
  • 15
    • 0000009816 scopus 로고
    • Serum uric acid in relation to age and physique in health and in coronary heart disease
    • Pubmed
    • Gertler MM, Garn SM, Levine SA. Serum uric acid in relation to age and physique in health and in coronary heart disease. Ann Intern Med. 1951; 34: 1421-1431. PubMed
    • (1951) Ann Intern Med. , vol.34 , pp. 1421-1431
    • Gertler, M.M.1    Garn, S.M.2    Levine, S.A.3
  • 16
    • 85047692424 scopus 로고
    • Serum uric acid. Its relationship to coronary heart disease risk factors and cardiovascular disease, Evans County, Georgia
    • doi:10.1001/archinte.132.3.401 PubMed
    • Klein R, Klein BE, Cornoni JC, Maready J, Cassel JC, Tyroler HA. Serum uric acid. Its relationship to coronary heart disease risk factors and cardiovascular disease, Evans County, Georgia. Arch Intern Med. 1973; 132: 401-410. doi:10.1001/archinte.132.3.401 PubMed
    • (1973) Arch Intern Med. , vol.132 , pp. 401-410
    • Klein, R.1    Klein, B.E.2    Cornoni, J.C.3    Maready, J.4    Cassel, J.C.5    Tyroler, H.A.6
  • 17
    • 0021930994 scopus 로고
    • Cardiovascular risk factors and obesity: are baseline levels of blood pressure, glucose, cholesterol and uric acid elevated prior to weight gain?
    • doi:10.1016/0021-9681 (85) 90111-0 PubMed
    • Burack RC, Keller JB, Higgins MW. Cardiovascular risk factors and obesity: are baseline levels of blood pressure, glucose, cholesterol and uric acid elevated prior to weight gain? J Chronic Dis. 1985; 38: 865-872. doi:10.1016/0021-9681 (85) 90111-0 PubMed
    • (1985) J Chronic Dis , vol.38 , pp. 865-872
    • Burack, R.C.1    Keller, J.B.2    Higgins, M.W.3
  • 18
    • 0028232632 scopus 로고
    • Association between serum uric acid and some cardiovascular risk factors in a Chinese population
    • doi:10.1136/pgmj.70.825.486 PubMed
    • Woo J, Swaminathan R, Cockram C, Lau E, Chan A. Association between serum uric acid and some cardiovascular risk factors in a Chinese population. Postgrad Med J. 1994; 70: 486-491. doi:10.1136/pgmj.70.825.486 PubMed
    • (1994) Postgrad Med J. , vol.70 , pp. 486-491
    • Woo, J.1    Swaminathan, R.2    Cockram, C.3    Lau, E.4    Chan, A.5
  • 19
    • 0030198372 scopus 로고    scopus 로고
    • Correlates of uric acid and its association with asymptomatic carotid atherosclerosis: the ARIC Study. Atherosclerosis Risk in Communities
    • doi:10.1016/S1047-2797(96)00052-X PubMed
    • Iribarren C, Folsom AR, Eckfeldt JH, McGovern PG, Nieto FJ. Correlates of uric acid and its association with asymptomatic carotid atherosclerosis: the ARIC Study. Atherosclerosis Risk in Communities. Ann Epidemiol. 1996; 6: 331-340. doi:10.1016/S1047-2797(96)00052-X PubMed
    • (1996) Ann Epidemiol. , vol.6 , pp. 331-340
    • Iribarren, C.1    Folsom, A.R.2    Eckfeldt, J.H.3    McGovern, P.G.4    Nieto, F.J.5
  • 20
    • 0033529386 scopus 로고    scopus 로고
    • Serum uric acid and risk for cardiovascular disease and death: the Framingham Heart Study
    • PubMed
    • Culleton BF, Larson MG, Kannel WB, Levy D. Serum uric acid and risk for cardiovascular disease and death: the Framingham Heart Study. Ann Intern Med. 1999; 131: 7-13. PubMed
    • (1999) Ann Intern Med. , vol.131 , pp. 7-13
    • Culleton, B.F.1    Larson, M.G.2    Kannel, W.B.3    Levy, D.4
  • 21
    • 0034630917 scopus 로고    scopus 로고
    • Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey
    • doi:10.1001/jama. 283.18.2404 PubMed
    • Fang J, Alderman MH. Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey. JAMA. 2000; 283: 2404-2410. doi:10.1001/jama. 283.18.2404 PubMed
    • (2000) JAMA. , vol.283 , pp. 2404-2410
    • Fang, J.1    Alderman, M.H.2
  • 23
    • 40849114570 scopus 로고    scopus 로고
    • Lipid peroxidation in hemodialysis patients: effect of vitamin C supplementation
    • doi:10.1016/j.clinbiochem. 2007.12.011 PubMed
    • Ferretti G, Bacchetti T, Masciangelo S, Pallotta G. Lipid peroxidation in hemodialysis patients: effect of vitamin C supplementation. Clin Biochem. 2008; 41: 381-386. doi:10.1016/j.clinbiochem. 2007.12.011 PubMed
    • (2008) Clin Biochem. , vol.41 , pp. 381-386
    • Ferretti, G.1    Bacchetti, T.2    Masciangelo, S.3    Pallotta, G.4
  • 24
    • 33748306000 scopus 로고    scopus 로고
    • Increased phagocytic nicotinamide adenine dinucleotide phosphate oxidasedependent superoxide production in patients with early chronic kidney disease
    • doi:10.1111/j.1523-1755. 20 05.09913.x PubMed
    • Fortuño A, Beloqui O, San José G, Moreno MU, Zalba G, Díez J. Increased phagocytic nicotinamide adenine dinucleotide phosphate oxidasedependent superoxide production in patients with early chronic kidney disease. Kidney Int Suppl. 2005; 99: S71-S75. doi:10.1111/j.1523-1755. 20 05 .09913.x PubMed
    • (2005) Kidney Int Suppl. , vol.99
    • Fortuño, A.1    Beloqui, O.2    San José, G.3    Moreno, M.U.4    Zalba, G.5    Díez, J.6
  • 25
    • 0032957595 scopus 로고    scopus 로고
    • Nitric oxide: discovery and impact on clinical medicine
    • PubMed
    • Moncada S. Nitric oxide: discovery and impact on clinical medicine. J R Soc Med. 1999; 92: 164-169. PubMed
    • (1999) J R Soc Med. , vol.92 , pp. 164-169
    • Moncada, S.1
  • 26
    • 0030894162 scopus 로고    scopus 로고
    • Oxidative stress: oxidants and antioxidants
    • PubMed
    • Sies H. Oxidative stress: oxidants and antioxidants. Exp Physiol. 1997; 82: 291-295. PubMed
    • (1997) Exp Physiol. , vol.82 , pp. 291-295
    • Sies, H.1
  • 27
    • 4043107129 scopus 로고    scopus 로고
    • Roles of oxidative stress and antioxidant therapy in chronic kidney disease and hypertension
    • doi:10.1097/00041552-200401000-00013 PubMed
    • Vaziri ND. Roles of oxidative stress and antioxidant therapy in chronic kidney disease and hypertension. Curr Opin Nephrol Hypertens. 2004; 13: 93-99. doi:10.1097/00041552-200401000-00013 PubMed
    • (2004) Curr Opin Nephrol Hypertens. , vol.13 , pp. 93-99
    • Vaziri, N.D.1
  • 28
    • 0442292075 scopus 로고    scopus 로고
    • Oxidative stress in uremia
    • doi:10.1097/00041552-200311000-000 04 PubMed
    • Himmelfarb J, Hakim RM. Oxidative stress in uremia. Curr Opin Nephrol Hypertens. 2003; 12: 593-598. doi:10.1097/00041552-200311000-000 04 PubMed
    • (2003) Curr Opin Nephrol Hypertens. , vol.12 , pp. 593-598
    • Himmelfarb, J.1    Hakim, R.M.2
  • 29
    • 34547830274 scopus 로고    scopus 로고
    • Atherogenesis and inflammation-was Virchow right?
    • doi:10.1093/ndt/gfm 112 PubMed
    • Methe H, Weis M. Atherogenesis and inflammation-was Virchow right? Nephrol Dial Transplant. 2007; 22: 1823-1827. doi:10.1093/ndt/gfm 112 PubMed
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 1823-1827
    • Methe, H.1    Weis, M.2
  • 31
    • 0034791021 scopus 로고    scopus 로고
    • Endothelial dysfunction and inflammation-is there a link?
    • doi:10.1093/ndt/16.10.1968 PubMed
    • Stenvinkel P. Endothelial dysfunction and inflammation-is there a link? Nephrol Dial Transplant. 2001; 16: 1968-1971. doi:10.1093/ndt/16.10.1968 PubMed
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 1968-1971
    • Stenvinkel, P.1
  • 32
    • 34250825264 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species mediated signaling in endothelial cells
    • Zhang DX, Gutterman DD. Mitochondrial reactive oxygen species mediated signaling in endothelial cells. Am J Physiol. 2007; 292: H2023-H2031.
    • (2007) Am J Physiol , vol.292
    • Zhang, D.X.1    Gutterman, D.D.2
  • 35
    • 33644874095 scopus 로고    scopus 로고
    • Relationship of serum uric acid to measures of endothelial function and atherosclerosis in healthy adults
    • doi:10.1111/j.1742-1241.2005.00621.x PubMed
    • Erdogan D, Gullu H, Caliskan M, Yildirim E, Bilgi M, Ulus T, Sezgin N, Muderrisoglu H. Relationship of serum uric acid to measures of endothelial function and atherosclerosis in healthy adults. Int J Clin Pract. 2005; 59: 1276-1282. doi:10.1111/j.1742-1241.2005.00621.x PubMed
    • (2005) Int J Clin Pract. , vol.59 , pp. 1276-1282
    • Erdogan, D.1    Gullu, H.2    Caliskan, M.3    Yildirim, E.4    Bilgi, M.5    Ulus, T.6    Sezgin, N.7    Muderrisoglu, H.8
  • 36
    • 0037024270 scopus 로고    scopus 로고
    • Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies
    • doi:10.1161/01.CIR. 000 00 17502.58595.ED PubMed
    • Doehner W, Schoene N, Rauchhaus M, Leyva-Leon F, Pavitt DV, Reaveley DA, Schuler G, Coats AJ, Anker SD, Hambrecht R. Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies. Circulation. 2002; 105: 2619-2624. doi:10.1161/01.CIR. 000 00 17502.58595.ED PubMed
    • (2002) Circulation. , vol.105 , pp. 2619-2624
    • Doehner, W.1    Schoene, N.2    Rauchhaus, M.3    Leyva-Leon, F.4    Pavitt, D.V.5    Reaveley, D.A.6    Schuler, G.7    Coats, A.J.8    Anker, S.D.9    Hambrecht, R.10
  • 37
    • 5344274543 scopus 로고    scopus 로고
    • Effect of hyperuricemia upon endothelial function in patients at increased cardiovascular risk
    • doi:10.1016/j.amjcard.2004.06.032 PubMed
    • Mercuro G, Vitale C, Cerquetani E, Zoncu S, Deidda M, Fini M, Rosano GM. Effect of hyperuricemia upon endothelial function in patients at increased cardiovascular risk. Am J Cardiol. 2004; 94: 932-935. doi:10.1016/j.amjcard.2004.06.032 PubMed
    • (2004) Am J Cardiol. , vol.94 , pp. 932-935
    • Mercuro, G.1    Vitale, C.2    Cerquetani, E.3    Zoncu, S.4    Deidda, M.5    Fini, M.6    Rosano, G.M.7
  • 38
    • 0016790889 scopus 로고
    • Hyperuricemia in coronary, cerebral and peripheral arterial disease: an explanation
    • doi:10. 1016/0306-9877(75)90011-0 PubMed
    • Newland H. Hyperuricemia in coronary, cerebral and peripheral arterial disease: an explanation. Med Hypotheses. 1975; 1: 152-155. doi:10. 1016/0306-9877(75)90011-0 PubMed
    • (1975) Med Hypotheses. , vol.1 , pp. 152-155
    • Newland, H.1
  • 39
    • 3242785541 scopus 로고    scopus 로고
    • Uric acid level as a risk factor for cardiovascular and allcause mortality in middle-aged men: a prospective cohort study
    • doi:10.1001/archinte.164.14. 1546 PubMed
    • Niskanen LK, Laaksonen DE, Nyyssönen K, Alfthan G, Lakka HM, Lakka TA, Salonen JT. Uric acid level as a risk factor for cardiovascular and allcause mortality in middle-aged men: a prospective cohort study. Arch Intern Med. 2004; 164: 1546-1551. doi:10.1001/archinte.164.14. 1546 PubMed
    • (2004) Arch Intern Med. , vol.164 , pp. 1546-1551
    • Niskanen, L.K.1    Laaksonen, D.E.2    Nyyssönen, K.3    Alfthan, G.4    Lakka, H.M.5    Lakka, T.A.6    Salonen, J.T.7
  • 40
    • 31644438457 scopus 로고    scopus 로고
    • Cardiovascular risk factors in chronic kidney disease
    • doi:10.1111/j.1523-1755. 2005.00551.x PubMed
    • Menon V, Gul A, Sarnak MJ. Cardiovascular risk factors in chronic kidney disease. Kidney Int. 2005; 68: 1413-1418. doi:10.1111/j.1523-1755. 2005.00551.x PubMed
    • (2005) Kidney Int. , vol.68 , pp. 1413-1418
    • Menon, V.1    Gul, A.2    Sarnak, M.J.3
  • 41
    • 0037512517 scopus 로고    scopus 로고
    • Traditional and emerging cardiovascular risk factors in endstage renal disease
    • doi:10.1046/j.1523-1755.63.s85.25.x
    • Zoccali C, Mallamaci F, Tripepi G. Traditional and emerging cardiovascular risk factors in endstage renal disease. Kidney Ibt. 2003; 63 (s85): 105-110. doi:10.1046/j.1523-1755.63.s85.25.x
    • (2003) Kidney Ibt , vol.63 , Issue.S85 , pp. 105-110
    • Zoccali, C.1    Mallamaci, F.2    Tripepi, G.3
  • 42
    • 0037047070 scopus 로고    scopus 로고
    • Allopurinol improves endothelial dysfunction in chronic heart failure
    • doi:10.1161/01.CIR.000 0022140.61460.1D PubMed
    • Farquharson CAJ, Butler R, Hill A, Belch JJ, Struthers AD. Allopurinol improves endothelial dysfunction in chronic heart failure. Circulation. 2002; 106: 221-226. doi:10.1161/01.CIR.000 0022140.61460.1D PubMed
    • (2002) Circulation. , vol.106 , pp. 221-226
    • Farquharson, C.A.J.1    Butler, R.2    Hill, A.3    Belch, J.J.4    Struthers, A.D.5
  • 43
    • 0034065857 scopus 로고    scopus 로고
    • Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension
    • PubMed
    • Butler R, Morris AD, Belch JJ, Hill A, Struthers AD. Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension. Hypertension. 2000; 35: 746-751. PubMed
    • (2000) Hypertension. , vol.35 , pp. 746-751
    • Butler, R.1    Morris, A.D.2    Belch, J.J.3    Hill, A.4    Struthers, A.D.5
  • 44
    • 0037469205 scopus 로고    scopus 로고
    • Xanthine oxidase inhibition reverses endothelial dysfunction in heavy smokers
    • doi:10.1161/01.CIR.0000046 448. 26751.58 PubMed
    • Guthikonda S, Sinkey C, Barenz T, Haynes WG. Xanthine oxidase inhibition reverses endothelial dysfunction in heavy smokers. Circulation. 2003; 107: 416-421. doi:10.1161/01.CIR.0000046 448. 26751.58 PubMed
    • (2003) Circulation. , vol.107 , pp. 416-421
    • Guthikonda, S.1    Sinkey, C.2    Barenz, T.3    Haynes, W.G.4
  • 45
    • 33845447368 scopus 로고    scopus 로고
    • High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid
    • George J, Carr E, Davies J, Belch JJ, Struthers A. High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid. Circulation. 2006; 114: 2508-2516.
    • (2006) Circulation. , vol.114 , pp. 2508-2516
    • George, J.1    Carr, E.2    Davies, J.3    Belch, J.J.4    Struthers, A.5
  • 46
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly
    • PubMed
    • Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol. 1996; 271: C1424-C1437. PubMed
    • (1996) Am J Physiol , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 48
    • 0037059510 scopus 로고    scopus 로고
    • Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview
    • doi:10.1161/hh0102.102330 PubMed
    • Ignarro LJ, Napoli C, Loscalzo J. Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview. Circ Res. 2002; 90: 21-28. doi:10.1161/hh0102.102330 PubMed
    • (2002) Circ Res. , vol.90 , pp. 21-28
    • Ignarro, L.J.1    Napoli, C.2    Loscalzo, J.3
  • 49
    • 0034057797 scopus 로고    scopus 로고
    • The vascular endothelium in chronic renal failure
    • PubMed
    • Morris ST, Jardine AG. The vascular endothelium in chronic renal failure. J Nephrol. 2000; 13: 96-105. PubMed
    • (2000) J Nephrol. , vol.13 , pp. 96-105
    • Morris, S.T.1    Jardine, A.G.2
  • 51
    • 0030837676 scopus 로고    scopus 로고
    • Endothelium-dependent vasodilatation and distensibility of large arteries in chronic haemodialysis patients
    • PubMed
    • van Guldener C, Lambert J, Janssen MJFY, Donker AJ, Stehouwer CD. Endothelium-dependent vasodilatation and distensibility of large arteries in chronic haemodialysis patients. Nephrol Dial Transplant. 1997; 12 (Suppl 2): 14-18. PubMed
    • (1997) Nephrol Dial Transplant. , vol.12 , Issue.2 , pp. 14-18
    • van Guldener, C.1    Lambert, J.2    Janssen, M.J.F.Y.3    Donker, A.J.4    Stehouwer, C.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.