Modeling of activity landscapes for drug discovery

Expert Opinion on Drug Discovery

Volumn 7, Issue 6, 2012, Pages 463-473

  Bajorath, Jürgen ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Activity cliffs; Activity landscapes; Compound data sets; Drug discovery; Graphical SAR analysis methods; Large scale SAR analysis; Medicinal chemistry; Structureactivity relationships (SARs)

Indexed keywords

G PROTEIN COUPLED RECEPTOR;

DRUG DEVELOPMENT; DRUG INDUSTRY; DRUG MECHANISM; DRUG TARGETING; PHENOTYPE; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION;

CHEMISTRY, PHARMACEUTICAL; COMPUTER SIMULATION; DRUG DESIGN; DRUG DISCOVERY; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS; SOFTWARE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84861496589     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2012.679616     Document Type: Review

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