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Volumn 5, Issue 6, 2010, Pages 847-858
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Computational analysis of multi-target structure-activity relationships to derive preference orders for chemical modifications toward target selectivity
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Author keywords
Analogue series; Pharmacophore features; Selectivity determinants; Structure activity relationships; Substituent effects
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Indexed keywords
BLOOD CLOTTING FACTOR 10A;
PROTEIN TYROSINE KINASE INHIBITOR;
SERINE PROTEINASE INHIBITOR;
TRYPSIN;
UROKINASE;
ARTICLE;
CHEMICAL MODIFICATION;
DECOMPOSITION;
DRUG POTENCY;
DRUG SELECTIVITY;
DRUG STRUCTURE;
DRUG TARGETING;
PHARMACOPHORE;
PRIORITY JOURNAL;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
SUBSTITUTION REACTION;
COMBINATORIAL CHEMISTRY TECHNIQUES;
DRUG DESIGN;
KINETICS;
PROTEIN KINASE INHIBITORS;
SERINE PROTEINASE INHIBITORS;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 77953114685
PISSN: 18607179
EISSN: 18607187
Source Type: Journal
DOI: 10.1002/cmdc.201000064 Document Type: Article |
Times cited : (26)
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References (18)
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