-
1
-
-
1942517868
-
Principles: Receptor theory in pharmacology
-
DOI 10.1016/j.tips.2004.02.012, PII S016561470400063X
-
Kenakin, T. Principles: Receptor Theory in Pharmacology Trends Pharmacol. Sci. 2004, 25, 186-192 (Pubitemid 38519909)
-
(2004)
Trends in Pharmacological Sciences
, vol.25
, Issue.4
, pp. 186-192
-
-
Kenakin, T.1
-
2
-
-
15744382504
-
Mechanistic explanation for the unique pharmacologic properties of receptor partial agonists
-
DOI 10.1016/j.biopha.2005.01.010
-
Zhu, B. T. Mechanistic Explanation for the Unique Pharmacologic Properties of Receptor Partial Agonists Biomed. Pharmacol. 2005, 59, 76-89 (Pubitemid 40417517)
-
(2005)
Biomedicine and Pharmacotherapy
, vol.59
, Issue.3
, pp. 76-89
-
-
Zhu, B.T.1
-
3
-
-
66249144426
-
The Structure and Function of G Protein-Coupled Receptors
-
Rosenbaum, D. M.; Rasmussen, S. G.; Kobilka, B. K. The Structure and Function of G Protein-Coupled Receptors Nature 2009, 459, 356-363
-
(2009)
Nature
, vol.459
, pp. 356-363
-
-
Rosenbaum, D.M.1
Rasmussen, S.G.2
Kobilka, B.K.3
-
4
-
-
78651390368
-
Binding the Receptor at Both Ends
-
Sprang, S. R. Binding the Receptor at Both Ends Nature 2011, 469, 172-173
-
(2011)
Nature
, vol.469
, pp. 172-173
-
-
Sprang, S.R.1
-
5
-
-
33846909764
-
"Phenotypic" pharmacology: The influence of cellular environment on G protein-coupled receptor antagonist and inverse agonist pharmacology
-
DOI 10.1016/j.bcp.2006.09.005, PII S0006295206005752
-
Nelson, C. P.; Challiss, R. A. 'Phenotypic' Pharmacology: the Influence of Cellular Environment on G Protein-Coupled Receptor Antagonist and Inverse Agonist Pharmacology Biochem. Pharmacol. 2007, 73, 737-751 (Pubitemid 46237612)
-
(2007)
Biochemical Pharmacology
, vol.73
, Issue.6
, pp. 737-751
-
-
Nelson, C.P.1
Challiss, R.A.J.2
-
6
-
-
33751284236
-
Inverse agonism or neutral antagonism at G-protein coupled receptors: A medicinal chemistry challenge worth pursuing?
-
DOI 10.1016/j.ejphar.2006.09.032, PII S0014299906010430
-
Greasley, P. J.; Clapham, J. C. Inverse Agonism or Neutral Antagonism at G Protein-Coupled Receptors: a Medicinal Chemistry Challenge worth Pursuing? Eur. J. Pharmacol. 2006, 553, 1-9 (Pubitemid 44794497)
-
(2006)
European Journal of Pharmacology
, vol.553
, Issue.1-3
, pp. 1-9
-
-
Greasley, P.J.1
Clapham, J.C.2
-
7
-
-
78650853329
-
The Chemical Basis of Pharmacology
-
Keiser, M. J.; Irwin, J. J.; Shoichet, B. K. The Chemical Basis of Pharmacology Biochemistry 2010, 49, 10267-10276
-
(2010)
Biochemistry
, vol.49
, pp. 10267-10276
-
-
Keiser, M.J.1
Irwin, J.J.2
Shoichet, B.K.3
-
8
-
-
78649844432
-
Activity Landscape Representations for Structure-Activity Relationship Analysis
-
Wassermann, A. M.; Wawer, M.; Bajorath, J. Activity Landscape Representations for Structure-Activity Relationship Analysis J. Med. Chem. 2010, 53, 8209-8223
-
(2010)
J. Med. Chem.
, vol.53
, pp. 8209-8223
-
-
Wassermann, A.M.1
Wawer, M.2
Bajorath, J.3
-
9
-
-
79959691886
-
-
ChEMBL; European Bioinformatics Institute (EBI): Cambridge,. (accessed March 2, 2011).
-
ChEMBL; European Bioinformatics Institute (EBI): Cambridge, 2010. http://www.ebi.ac.uk/chembl/ (accessed March 2, 2011).
-
(2010)
-
-
-
10
-
-
53549123322
-
Structure-Activity Relationship Anatomy by Network-like Similarity Graphs and Local Structure-Activity Relationship Indices
-
Wawer, M.; Peltason, L.; Weskamp, N.; Teckentrup, A.; Bajorath, J. Structure-Activity Relationship Anatomy by Network-like Similarity Graphs and Local Structure-Activity Relationship Indices J. Med. Chem. 2008, 51, 6075-6084
-
(2008)
J. Med. Chem.
, vol.51
, pp. 6075-6084
-
-
Wawer, M.1
Peltason, L.2
Weskamp, N.3
Teckentrup, A.4
Bajorath, J.5
-
11
-
-
75749102958
-
SARANEA: A Freely Available Program to Mine Structure-Activity and Structure-Selectivity Relationship Information in Compound Data Sets
-
Lounkine, E.; Wawer, M.; Wassermann, A. M.; Bajorath, J. SARANEA: A Freely Available Program to Mine Structure-Activity and Structure-Selectivity Relationship Information in Compound Data Sets J. Chem. Inf. Model 2010, 50, 68-78
-
(2010)
J. Chem. Inf. Model
, vol.50
, pp. 68-78
-
-
Lounkine, E.1
Wawer, M.2
Wassermann, A.M.3
Bajorath, J.4
-
13
-
-
77952772341
-
Extended-Connectivity Fingerprints
-
Rogers, D.; Hahn, M. Extended-Connectivity Fingerprints J. Chem. Inf. Model. 2010, 50, 742-754
-
(2010)
J. Chem. Inf. Model.
, vol.50
, pp. 742-754
-
-
Rogers, D.1
Hahn, M.2
-
14
-
-
54249156879
-
-
Student ed.; Version 6.1; Accelrys, Inc.: San Diego, CA.
-
Scitegic Pipeline Pilot, Student ed.; Version 6.1; Accelrys, Inc.: San Diego, CA, 2007.
-
(2007)
Scitegic Pipeline Pilot
-
-
-
15
-
-
2042489375
-
-
Symyx Software: San Ramon, CA.
-
MACCS Structural Keys; Symyx Software: San Ramon, CA, 2005.
-
(2005)
MACCS Structural Keys
-
-
|