Visuomotor impairment in early-stage alzheimer's disease: Changes in relative timing of eye and hand movements

Journal of Alzheimer's Disease

Volumn 30, Issue 1, 2012, Pages 131-143

  Verheij, Simone ^a   Muilwijk, Danya ^a   Pel, Johan J M ^a   Van Der Cammen, Tischa J M ^a   Mattace Raso, Francesco U S ^a   Van Der Steen, Johannes ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Alzheimer's disease; dementia; eye hand coordination; motor activity; visuomotor integration

Indexed keywords

GALANTAMINE; RIVASTIGMINE;

ADULT; AGED; ALZHEIMER DISEASE; ANTICIPATION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EYE HAND COORDINATION; EYE MOVEMENT; EYE TRACKING; EYE TRACKING DEVICE; FEMALE; HAND MOVEMENT; HUMAN; KINEMATICS; LATENT PERIOD; MALE; MEDICAL DEVICE; MOTION CAPTURING SYSTEM; MOTOR PERFORMANCE; PARIETAL CORTEX; PRIORITY JOURNAL; STIMULUS; TASK PERFORMANCE; TOUCH SCREEN; VISUOMOTOR COORDINATION;

EID: 84861493990     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-111883     Document Type: Article

References (28)

1. Querfurth HW, LaFerla FM (2010) Alzheimer's disease. N Engl J Med 362, 329-344.
2. Lechowski L, Van Pradelles S, LeCrane M, d'Arailh L, Tortrat D, Teillet L, Vellas B (2010) Patterns of loss of basic activities of daily living in Alzheimer patients: A cross-sectional study of the French REAL cohort. Dement Geriatr Cogn Disord 29, 46-54.
3. Deiber MP, Ibanez V, Sadato N, Hallett M (1996) Cerebral structures participating in motor preparation in humans: A positron emission tomography study. J Neurophysiol 75, 233-247. (Pubitemid 26072036)
4. Marconi B, Genovesio A, Battaglia-Mayer A, Ferraina S, Squatrito S, Molinari M, Lacquaniti F, Caminiti R (2001) Eye-hand coordination during reaching. I. Anatomical relationships between parietal and frontal cortex. Cereb Cortex 11, 513-527. (Pubitemid 32488379)
5. Pierrot-Deseilligny C, Milea D, Muri RM (2004) Eye movement control by the cerebral cortex. Curr Opin Neurol 17, 17-25. (Pubitemid 38316775)
6. Van Der Werf J, Buchholz VN, Jensen O, Medendorp WP (2009) Neuronal synchronization in human parietal cortex during saccade planning. Behav Brain Res 205, 329-335.
7. Galati G, Committeri G, Pitzalis S, Pelle G, Patria F, Fattori P, Galletti C (2011) Intentional signals during saccadic and reaching delays in the human posterior parietal cortex. Eur J Neurosci 34, 1871-1885.
8. Tippett WJ, Black SE (2008) Regional cerebral blood flow correlates of visuospatial tasks in Alzheimer's disease. J Int Neuropsychol Soc 14, 1034-1045.
9. Salat DH, Greve DN, Pacheco JL, Quinn BT, Helmer KG, Buckner RL, Fischl B (2009) Regional white matter volume differences in nondemented aging and Alzheimer's disease. Neuroimage 44, 1247-1258.
10. Zhang HY, Wang SJ, Xing J, Liu B, Ma ZL, Yang M, Zhang ZJ, Teng GJ (2009) Detection of PCC functional connectivity characteristics in resting-state fMRI in mild Alzheimer's disease. Behav Brain Res 197, 103-108.
11. Yan JH, Rountree S, Massman P, Doody RS, Li H (2008) Alzheimer's disease and mild cognitive impairment deteriorate fine movement control. J Psychiatr Res 42, 1203-1212.
12. Buchman AS, Bennett DA (2011) Loss of motor function in preclinical Alzheimer's disease. Expert Rev Neurother 11, 665-676.
13. Tippett WJ, Sergio LE (2006) Visuomotor integration is impaired in early stage Alzheimer's disease. Brain Res 1102, 92-102. (Pubitemid 44109681)
14. Gowen E, Miall RC (2006) Eye-hand interactions in tracing and drawing tasks. Hum Mov Sci 25, 568-585. (Pubitemid 44550705)
15. Tramper JJ, Gielen CC (2011) Visuomotor coordination is different for different directions in three-dimensional space. J Neurosci 31, 7857-7866.
16. American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders: DSM-IV-TR, American Psychiatric Pub.
17. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: Report ofthe NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944. (Pubitemid 14076461)
18. Verhage F (1964) Intelligence and age: Research among the Dutch between 7 and 77 years of age, van Gorcum, Assen.
19. Vertesi A, Lever JA, Molloy DW, Sanderson B, Tuttle I, Poko-radi L, Principi E (2001) Standardized Mini-Mental State Examination. Use and interpretation. Can Fam Physician 47, 2018-2023. (Pubitemid 33107474)
20. Tippett WJ, Krajewski A, Sergio LE (2007) Visuomotor integration is compromised in Alzheimer's disease patients reaching for remembered targets. Eur Neurol 58, 1-11. (Pubitemid 47038154)
21. Crawford TJ, Higham S, Renvoize T, Patel J, Dale M, Suriya A, Tetley S (2005) Inhibitory control of saccadic eye movements and cognitive impairment in Alzheimer's disease. Biol Psychiatry 57, 1052-1060. (Pubitemid 40603088)
22. Boxer AL, Garbutt S, Rankin KP, Hellmuth J, Neuhaus J, Miller BL, Lisberger SG (2006) Medial versus lateral frontal lobe contributions to voluntary saccade control as revealed by the studyofpatients withfrontal lobe degeneration. J Neurosci 26, 6354-6363.
23. Shafiq-Antonacci R, Maruff P, Masters C, Currie J (2003) Spectrum of saccade system function in Alzheimer disease. Arch Neurol 60, 1272-1278. (Pubitemid 37099635)
24. Garbutt S, Matlin A, Hellmuth J, Schenk AK, Johnson JK, Rosen H, Dean D, Kramer J, Neuhaus J, Miller BL, Lisberger SG, Boxer AL (2008) Oculomotor function in frontotemporal lobar degeneration, related disorders and Alzheimer's disease. Brain 131, 1268-1281.
25. Kaufman LD, Pratt J, Levine B, Black SE (2010) Anti-saccades: A probe into the dorsolateral prefrontal cortex in Alzheimer's disease. A critical review. J Alzheimers Dis 19, 781-793.
26. Muhlack S, Przuntek H, Muller T (2006) Transdermal rivastigmine treatment does not worsen impaired performance of complex motions in patients with Alzheimer's disease. Pharmacopsychiatry 39, 16-19. (Pubitemid 43235445)
27. Munoz DP, Everling S (2004) Look away: The anti-saccade task and the voluntary control of eye movement. Nat Rev Neurosci 5, 218-228. (Pubitemid 38252478)
28. Crawford JD, Henriques DY, Medendorp WP (2011) Three-dimensional transformations for goal-directed action. Annu Rev Neurosci 34, 309-331.