Patterns of loss of basic activities of daily living in Alzheimer patients: A cross-sectional study of the French REAL cohort

Dementia and Geriatric Cognitive Disorders

Volumn 29, Issue 1, 2010, Pages 46-54

  Lechowski, Laurent ^a,b,f   Van Pradelles, Sophie ^a   Le Crane, Marine ^a   D'Arailh, Lydie ^a   Tortrat, Danièle ^a,b   Teillet, Laurent ^a,b   Vellas, Bruno ^c,d,e  

^a LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^b Île de France Ouest University Paris   (France)

^c CHU PURPAN   (France)

^d Serv Univ Psychiat l'Enfant l'A   (France)

^e INSERM   (France)

^f Versailles Saint Quentin en Yvelines University   (France)

Author keywords

Alzheimer's disease, cohort study; Basic activities of daily living; Disability; Functional decline

Indexed keywords

ADL DISABILITY; ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BATH; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; FEEDING; FEMALE; GROOMING; HUMAN; LAWTON INSTRUMENTAL ACTIVITIES OF DAILY LIVING SCALE; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; MOBILIZATION; PATIENT ASSESSMENT; PHYSICAL ACTIVITY; PRIORITY JOURNAL; SELF CARE;

EID: 75149180115     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000264632     Document Type: Article

References (33)

1. Zhu CW, Scarmeas N, Torgan R, Albert M, Brandt J, Blacker D, et al: Clinical characteristics and longitudinal changes of informal cost of Alzheimer's disease in the community. J Am Geriatr Soc 2006; 54: 1596-1602.
2. Andersen CK, Wittrup-Jensen KU, Lolk A, Andersen K, Kragh-Sorensen P: Ability to perform activities of daily living is the main factor affecting quality of life in patients with dementia. Health Qual Life Outcomes 2004; 2: 52.
3. Mucha L, Shaohung S, Cuffel B, McRae T, Mark TL, Del Valle M: Comparison of cholinesterase inhibitor utilization patterns and associated health care costs in Alzheimer's disease. J Manag Care Pharm 2008; 14: 451-461.
4. Galasko D, Kershaw PR, Schneider L, Zhu Y, Tariot PN: Galantamine maintains ability to perform activities of daily living in patients with Alzheimer's disease. J Am Geriatr Soc 2004; 52: 1070-1076.
5. Paulino Ramirez Diaz S, Gil Gregorio P, Manuel Ribera Casado J, Reynish E, Jean Ousset P, Vellas B, et al: The need for a consensus in the use of assessment tools for Alzheimer's disease: the Feasibility Study (assessment tools for dementia in Alzheimer Centres across Europe), a European Alzheimer's Disease Consortium's (EADC) survey. Int J Geriatr Psychiatry 2005; 20: 744-748.
6. Green CR, Mohs RC, Schmeidler J, Aryan M, Davis KL: Functional decline in Alzheimer's disease: a longitudinal study. J Am Geriatr Soc 1993; 41: 654-661.
7. Barberger-Gateau P, Fabrigoule C, Helmer C, Rouch I, Dartigues JF: Functional impairment in instrumental activities of daily living: an early clinical sign of dementia? J Am Geriatr Soc 1999; 47: 456-462.
8. Lechowski L, de Stampa M, Denis B, Tortrat D, Chassagne P, Robert P, et al: Patterns of loss of abilities in instrumental activities of daily living in Alzheimer's disease: the REAL cohort study. Dement Geriatr Cogn Disord 2008; 25: 46-53.
9. Gillette-Guyonnet S, Nourhashemi F, Andrieu S, Cantet C, Micas M, Ousset PJ, et al: The REAL.FR research program on Alzheimer's disease and its management: methods and preliminary results. J Nutr Health Aging 2003; 7: 91-96.
10. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984; 34: 939-944.
11. APA: Diagnostic and Statistical Manual of Mental Disorders. Washington, APA, 1994.
12. Zec RF, Landreth ES, Vicari SK, Feldman E, Belman J, Andrise A, et al: Alzheimer disease assessment scale: useful for both early detection and staging of dementia of the Alzheimer type. Alzheimer Dis Assoc Disord 1992; 6: 89-102.
13. Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J: The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 1994; 44: 2308-2314.
14. Morris JC: The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 1993; 43: 2412-2414.
15. Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW: Studies of illness in the aged - the index of ADL: a standardized measure of biological and psychosocial function. JAMA 1963; 185: 914-919.
16. Lawton MP, Brody EM: Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969; 9: 179-186.
17. Njegovan V, Hing MM, Mitchell SL, Molnar FJ: The hierarchy of functional loss associated with cognitive decline in older persons. J Gerontol A Biol Sci Med Sci 2001; 56:M638-M643.
18. Fillenbaum GG, Smyer MA: The development, validity, and reliability of the OARS multidimensional functional assessment questionnaire. J Gerontol 1981; 36: 428-1234
19. Derouesne C, Thibault S, Lozeron P, Baudouin- Madec V, Piquard A, Lacomblez L: Perturbations of activities of daily living in Alzheimer's disease: a study of 172 patients using a questionnaire completed by caregivers (in French). Rev Neurol (Paris) 2002; 158: 684-700.
20. Hinton L, Tomaszewski Farias S, Wegelin J: Neuropsychiatric symptoms are associated with disability in cognitively impaired Latino elderly with and without dementia: results from the Sacramento Area Latino study on Aging. Int J Geriatr Psychiatry 2008; 23: 102-108.
21. Bouwens SF, van Heugten CM, Aalten P, Wolfs CA, Baarends EM, van Menxel DA, et al: Relationship between measures of dementia severity and observation of daily life functioning as measured with the Assessment of Motor and Process Skills (AMPS). Dement Geriatr Cogn Disord 2008; 25: 81-87.
22. Hsiung GY, Alipour S, Jacova C, Grand J, Gauthier S, Black SE, et al: Transition from cognitively impaired not demented to Alzheimer's disease: an analysis of changes in functional abilities in a dementia clinic cohort. Dement Geriatr Cogn Disord 2008; 25: 483-490.
23. Formiga F, Lopez-Soto A, Navarro M, Riera- Mestre A, Bosch X, Pujol R: Hospital deaths of people aged 90 and over: end-of-life palliative care management. Gerontology 2008; 54: 148-152.
24. Atti AR, Palmer K, Volpato S, Winblad B, De Ronchi D, Fratiglioni L: Late-life body mass index and dementia incidence: nine-year follow- up data from the Kungsholmen Project. J Am Geriatr Soc 2008; 56: 111-116.
25. Stout JC, Wyman MF, Johnson SA, Peavy GM, Salmon DP: Frontal behavioral syndromes and functional status in probable Alzheimer disease. Am J Geriatr Psychiatry 2003; 11: 683-686.
26. Lechowski L, De Stampa M, Tortrat D, Teillet L, Benoit M, Robert PH, et al: Predictive factors of rate of loss of autonomy in Alzheimer's disease patients: a prospective study of the REAL.FR cohort. J Nutr Health Aging 2005; 9: 100-104.
27. Lechowski L, Benoit M, Chassagne P, Vedel I, Tortrat D, Teillet L, et al: Persistent apathy in Alzheimer's disease as an independent factor of rapid functional decline: the REAL longitudinal cohort study. Int J Geriatr Psychiatry 2008; 24: 341-346.
28. Boyle PA, Malloy PF, Salloway S, Cahn- Weiner DA, Cohen R, Cummings JL: Executive dysfunction and apathy predict functional impairment in Alzheimer disease. Am J Geriatr Psychiatry 2003; 11: 214-221.
29. Marshall GA, Fairbanks LA, Tekin S, Vinters HV, Cummings JL: Neuropathologic correlates of activities of daily living in Alzheimer disease. Alzheimer Dis Assoc Disord 2006; 20: 56-59.
30. Santillan CE, Fritsch T, Geldmacher DS: Development of a scale to predict decline in patients with mild Alzheimer's disease. J Am Geriatr Soc 2003; 51: 91-95.
31. Perneczky R, Pohl C, Sorg C, Hartmann J, Tosic N, Grimmer T, et al: Impairment of activities of daily living requiring memory or complex reasoning as part of the MCI syndrome. Int J Geriatr Psychiatry 2006; 21: 158-162.
32. Atchison TB, Massman PJ, Doody RS: Baseline cognitive function predicts rate of decline in basic-care abilities of individuals with dementia of the Alzheimer's type. Arch Clin Neuropsychol 2007; 22: 99-107.
33. Courtney C, Farrell D, Gray R, Hills R, Lynch L, Sellwood E, et al: Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): randomised double-blind trial. Lancet 2004; 363: 2105-2115.