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Volumn 19, Issue 6, 2012, Pages 565-574

Bortezomib reverses the proliferative and antiapoptotic effect of neuropeptides on prostate cancer cells

Author keywords

Bombesin; Bortezomib; Endothelin 1; Prostate cancer; Proteasome

Indexed keywords

BOMBESIN; BORTEZOMIB; CASPASE 3; ENDOTHELIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; NEUROPEPTIDE; PROTEASOME; PROTEIN BAD; PROTEIN KINASE B; PROTEIN P21; PROTEIN P27; PROTEIN P44; PROTEIN P53; VASCULOTROPIN;

EID: 84861483092     PISSN: 09198172     EISSN: 14422042     Source Type: Journal    
DOI: 10.1111/j.1442-2042.2012.02967.x     Document Type: Article
Times cited : (13)

References (52)
  • 2
    • 0028103841 scopus 로고
    • Characterization of high-affinity receptors for bombesin/gastrin releasing peptide on the human prostate cancer cell lines PC-3 and DU-145: internalization of receptor bound 125I-(Tyr4) bombesin by tumor cells
    • Reile H, Armatis PE, Schally AV. Characterization of high-affinity receptors for bombesin/gastrin releasing peptide on the human prostate cancer cell lines PC-3 and DU-145: internalization of receptor bound 125I-(Tyr4) bombesin by tumor cells. Prostate 1994; 25: 29-38.
    • (1994) Prostate , vol.25 , pp. 29-38
    • Reile, H.1    Armatis, P.E.2    Schally, A.V.3
  • 3
    • 0030014619 scopus 로고    scopus 로고
    • Bombesin specifically induces intracellular calcium mobilization via gastrin-releasing peptide receptors in human prostate cancer cells
    • Aprikian AG, Han K, Chevalier S, Bazinet M, Viallet J. Bombesin specifically induces intracellular calcium mobilization via gastrin-releasing peptide receptors in human prostate cancer cells. J. Mol. Endocrinol. 1996; 16: 297-306.
    • (1996) J. Mol. Endocrinol. , vol.16 , pp. 297-306
    • Aprikian, A.G.1    Han, K.2    Chevalier, S.3    Bazinet, M.4    Viallet, J.5
  • 4
    • 0027056907 scopus 로고
    • The inhibition of the paracrine progression of prostate cancer as an approach to early therapy of prostatic carcinoma
    • SUPPL.
    • Logothetis C, Hoosein N. The inhibition of the paracrine progression of prostate cancer as an approach to early therapy of prostatic carcinoma. J. Cell. Biochem. 1992; 50 (Suppl 16H): 128-34.
    • (1992) J. Cell. Biochem. , vol.50 , Issue.16 H , pp. 128-134
    • Logothetis, C.1    Hoosein, N.2
  • 5
    • 0013543367 scopus 로고
    • The human ET family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes
    • Inoue A, Yanagisawa M, Kimura S etal. The human ET family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc. Natl. Acad. Sci. U.S.A. 1989; 86: 2863-7.
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 2863-2867
    • Inoue, A.1    Yanagisawa, M.2    Kimura, S.3
  • 6
    • 0031741856 scopus 로고    scopus 로고
    • Signal transduction pathways in the mitogenic response to G protein coupled neuropeptide receptor agonists
    • Rozengurt E. Signal transduction pathways in the mitogenic response to G protein coupled neuropeptide receptor agonists. J. Cell. Physiol. 1998; 177: 507-17.
    • (1998) J. Cell. Physiol. , vol.177 , pp. 507-517
    • Rozengurt, E.1
  • 8
    • 0029085123 scopus 로고
    • Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate
    • Nelson JB, Hedican SP, George DJ etal. Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat. Med. 1995; 1: 944-9.
    • (1995) Nat. Med. , vol.1 , pp. 944-949
    • Nelson, J.B.1    Hedican, S.P.2    George, D.J.3
  • 9
    • 0030047858 scopus 로고    scopus 로고
    • Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer
    • Nelson JB, Chan-Tack K, Hedican SP etal. Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer. Cancer Res. 1996; 56: 663-8.
    • (1996) Cancer Res. , vol.56 , pp. 663-668
    • Nelson, J.B.1    Chan-Tack, K.2    Hedican, S.P.3
  • 10
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li Q, Verma IM. NF-kappaB regulation in the immune system. Nat. Rev. Immunol. 2002; 2: 725-34.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 11
    • 0029146930 scopus 로고
    • Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin proteasome pathway
    • Chen Z, Hagler J, Palombella VJ etal. Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin proteasome pathway. Genes Dev. 1995; 9: 1586-97.
    • (1995) Genes Dev. , vol.9 , pp. 1586-1597
    • Chen, Z.1    Hagler, J.2    Palombella, V.J.3
  • 13
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: the cell's response to p53
    • Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat. Rev. Cancer 2002; 2: 594-604.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 14
    • 0034320568 scopus 로고    scopus 로고
    • Mechanisms of apoptosis
    • Reed JC. Mechanisms of apoptosis. Am. J. Pathol. 2000; 157: 1415-30.
    • (2000) Am. J. Pathol. , vol.157 , pp. 1415-1430
    • Reed, J.C.1
  • 15
    • 0642349188 scopus 로고    scopus 로고
    • Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts
    • Williams S, Pettaway C, Song R, Papandreou C, Logothetis C, McConkey DJ. Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts. Mol. Cancer Ther. 2003; 2: 835-43.
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 835-843
    • Williams, S.1    Pettaway, C.2    Song, R.3    Papandreou, C.4    Logothetis, C.5    McConkey, D.J.6
  • 16
    • 2342667387 scopus 로고    scopus 로고
    • The development of proteasome inhibitors as anticancer drugs
    • Adams J. The development of proteasome inhibitors as anticancer drugs. Cancer Cell 2004; 5: 417-21.
    • (2004) Cancer Cell , vol.5 , pp. 417-421
    • Adams, J.1
  • 17
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • Richardson PG, Barlogie B, Berenson J etal. A phase 2 study of bortezomib in relapsed, refractory myeloma. N. Engl. J. Med. 2003; 348: 2609-17.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 18
    • 0345447210 scopus 로고    scopus 로고
    • Velcade: U.S. FDA approval for the treatment of multiple myeloma progressing on prior therapy
    • Kane RC, Bross PF, Farrell AT, Pazdur R. Velcade: U.S. FDA approval for the treatment of multiple myeloma progressing on prior therapy. Oncologist 2003; 8: 508-13.
    • (2003) Oncologist , vol.8 , pp. 508-513
    • Kane, R.C.1    Bross, P.F.2    Farrell, A.T.3    Pazdur, R.4
  • 19
    • 79955788758 scopus 로고    scopus 로고
    • Inverse baseline expression pattern of the NEP/neuropeptides and NFκB/proteasome pathways in androgen-dependent and androgen-independent prostate cancer cells
    • Patrikidou A, Vlachostergios PJ, Voutsadakis IA etal. Inverse baseline expression pattern of the NEP/neuropeptides and NFκB/proteasome pathways in androgen-dependent and androgen-independent prostate cancer cells. Cancer Cell Int. 2011; 11: 13-21.
    • (2011) Cancer Cell Int. , vol.11 , pp. 13-21
    • Patrikidou, A.1    Vlachostergios, P.J.2    Voutsadakis, I.A.3
  • 20
    • 0035870258 scopus 로고    scopus 로고
    • Neutral endopeptidase inhibits neuropeptide-mediated transactivation of the insulin-like growth factor receptor-Akt cell survival pathway
    • Sumitomo M, Milowsky MI, Shen R etal. Neutral endopeptidase inhibits neuropeptide-mediated transactivation of the insulin-like growth factor receptor-Akt cell survival pathway. Cancer Res. 2001; 61: 3294-8.
    • (2001) Cancer Res. , vol.61 , pp. 3294-3298
    • Sumitomo, M.1    Milowsky, M.I.2    Shen, R.3
  • 21
    • 0038107752 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase mediates bombesin-induced mitogenic responses in prostate cancer cells
    • Xiao D, Qu X, Weber HC. Activation of extracellular signal-regulated kinase mediates bombesin-induced mitogenic responses in prostate cancer cells. Cell. Signal. 2003; 15: 945-53.
    • (2003) Cell. Signal. , vol.15 , pp. 945-953
    • Xiao, D.1    Qu, X.2    Weber, H.C.3
  • 22
    • 0034095227 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases are involved in the antiapoptotic effect of endothelin-1
    • Wu-Wong JR, Chiou WJ, Wang J. Extracellular signal-regulated kinases are involved in the antiapoptotic effect of endothelin-1. J. Pharmacol. Exp. Ther. 2000; 293: 514-21.
    • (2000) J. Pharmacol. Exp. Ther. , vol.293 , pp. 514-521
    • Wu-Wong, J.R.1    Chiou, W.J.2    Wang, J.3
  • 23
    • 3442882798 scopus 로고    scopus 로고
    • Bortezomib as a potential treatment for prostate cancer
    • Papandreou CN, Logothetis CJ. Bortezomib as a potential treatment for prostate cancer. Cancer Res. 2004; 64: 5036-43.
    • (2004) Cancer Res. , vol.64 , pp. 5036-5043
    • Papandreou, C.N.1    Logothetis, C.J.2
  • 24
    • 0036680137 scopus 로고    scopus 로고
    • Mechanisms of constitutive NF-kappaB activation in human prostate cancer cells
    • Suh J, Payvandi F, Edelstein LC etal. Mechanisms of constitutive NF-kappaB activation in human prostate cancer cells. Prostate 2002; 52: 183-200.
    • (2002) Prostate , vol.52 , pp. 183-200
    • Suh, J.1    Payvandi, F.2    Edelstein, L.C.3
  • 25
    • 16644397046 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate
    • Sweeney C, Li L, Shanmugam R etal. Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate. Clin. Cancer Res. 2004; 10: 5501-7.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 5501-5507
    • Sweeney, C.1    Li, L.2    Shanmugam, R.3
  • 26
    • 53049103521 scopus 로고    scopus 로고
    • The nuclear factor-kappaB pathway controls the progression of prostate cancer to androgen-independent growth
    • Jin RJ, Lho Y, Connelly L etal. The nuclear factor-kappaB pathway controls the progression of prostate cancer to androgen-independent growth. Cancer Res. 2008; 68: 6762-9.
    • (2008) Cancer Res. , vol.68 , pp. 6762-6769
    • Jin, R.J.1    Lho, Y.2    Connelly, L.3
  • 28
    • 0036181371 scopus 로고    scopus 로고
    • Development of the proteasome inhibitor PS-341
    • Adams J. Development of the proteasome inhibitor PS-341. Oncologist 2002; 7: 9-16.
    • (2002) Oncologist , vol.7 , pp. 9-16
    • Adams, J.1
  • 29
    • 1842866995 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 down-regulates prostate-specific antigen (PSA) and induces growth arrest and apoptosis of androgen-dependent human prostate cancer LNCaP cells
    • Ikezoe T, Yang Y, Saito T, Koeffler HP, Taguchi H. Proteasome inhibitor PS-341 down-regulates prostate-specific antigen (PSA) and induces growth arrest and apoptosis of androgen-dependent human prostate cancer LNCaP cells. Cancer Sci. 2004; 95: 271-5.
    • (2004) Cancer Sci. , vol.95 , pp. 271-275
    • Ikezoe, T.1    Yang, Y.2    Saito, T.3    Koeffler, H.P.4    Taguchi, H.5
  • 30
    • 79952772716 scopus 로고    scopus 로고
    • Inhibition of tumor growth and sensitization to chemotherapy by RNA interference targeting interleukin-6 in the androgen-independent human prostate cancer PC3 model
    • Sakai I, Miyake H, Terakawa T, Fujisawa M. Inhibition of tumor growth and sensitization to chemotherapy by RNA interference targeting interleukin-6 in the androgen-independent human prostate cancer PC3 model. Cancer Sci. 2011; 102: 769-75.
    • (2011) Cancer Sci. , vol.102 , pp. 769-775
    • Sakai, I.1    Miyake, H.2    Terakawa, T.3    Fujisawa, M.4
  • 31
    • 2942692143 scopus 로고    scopus 로고
    • Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer
    • Papandreou CN, Daliani DD, Nix D etal. Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J. Clin. Oncol. 2004; 22: 2108-21.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 2108-2121
    • Papandreou, C.N.1    Daliani, D.D.2    Nix, D.3
  • 32
    • 0141925950 scopus 로고    scopus 로고
    • Drug interactions between the proteasome inhibitor bortezomib and cytotoxic chemotherapy, tumor necrosis factor (TNF) alpha, and TNF-related apoptosis-inducing ligand in prostate cancer
    • An J, Sun YP, Adams J, Fisher M, Belldegrun A, Rettig MB. Drug interactions between the proteasome inhibitor bortezomib and cytotoxic chemotherapy, tumor necrosis factor (TNF) alpha, and TNF-related apoptosis-inducing ligand in prostate cancer. Clin. Cancer Res. 2003; 9: 4537-45.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 4537-4545
    • An, J.1    Sun, Y.P.2    Adams, J.3    Fisher, M.4    Belldegrun, A.5    Rettig, M.B.6
  • 33
    • 38749133727 scopus 로고    scopus 로고
    • Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis
    • Thorpe JA, Christian PA, Schwarze SR. Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis. Prostate 2008; 68: 200-9.
    • (2008) Prostate , vol.68 , pp. 200-209
    • Thorpe, J.A.1    Christian, P.A.2    Schwarze, S.R.3
  • 34
    • 66149126567 scopus 로고    scopus 로고
    • Velcade sensitizes prostate cancer cells to TRAIL induced apoptosis and suppresses tumor growth in vivo
    • Christian PA, Thorpe JA, Schwarze SR. Velcade sensitizes prostate cancer cells to TRAIL induced apoptosis and suppresses tumor growth in vivo. Cancer Biol. Ther. 2009; 8: 73-80.
    • (2009) Cancer Biol. Ther. , vol.8 , pp. 73-80
    • Christian, P.A.1    Thorpe, J.A.2    Schwarze, S.R.3
  • 35
    • 0043287140 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells
    • Johnson TR, Stone K, Nikrad M etal. The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells. Oncogene 2003; 22: 4953-63.
    • (2003) Oncogene , vol.22 , pp. 4953-4963
    • Johnson, T.R.1    Stone, K.2    Nikrad, M.3
  • 36
    • 49849089793 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3′-untranslated region
    • Kandasamy K, Kraft AS. Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3′-untranslated region. Mol. Cancer Ther. 2008; 7: 1091-100.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 1091-1100
    • Kandasamy, K.1    Kraft, A.S.2
  • 37
    • 15944387964 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim
    • Nikrad M, Johnson T, Puthalalath H, Coultas L, Adams J, Kraft AS. The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. Mol. Cancer Ther. 2005; 4: 443-9.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 443-449
    • Nikrad, M.1    Johnson, T.2    Puthalalath, H.3    Coultas, L.4    Adams, J.5    Kraft, A.S.6
  • 38
    • 19644395562 scopus 로고    scopus 로고
    • Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells
    • Lashinger LM, Zhu K, Williams SA, Shrader M, Dinney CP, McConkey DJ. Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells. Cancer Res. 2005; 65: 4902-8.
    • (2005) Cancer Res. , vol.65 , pp. 4902-4908
    • Lashinger, L.M.1    Zhu, K.2    Williams, S.A.3    Shrader, M.4    Dinney, C.P.5    McConkey, D.J.6
  • 39
    • 0035337720 scopus 로고    scopus 로고
    • I kappa B kinase is critical for TNF-alpha-induced VCAM1 gene expression in renal tubular epithelial cells
    • Tu Z, Kelley VR, Collins T, Lee FS. I kappa B kinase is critical for TNF-alpha-induced VCAM1 gene expression in renal tubular epithelial cells. J. Immunol. 2001; 166: 6839-46.
    • (2001) J. Immunol. , vol.166 , pp. 6839-6846
    • Tu, Z.1    Kelley, V.R.2    Collins, T.3    Lee, F.S.4
  • 40
    • 34248233130 scopus 로고    scopus 로고
    • Loss of mitochondrial membrane potential is inhibited by bombesin in etoposide-induced apoptosis in PC-3 prostate carcinoma cells
    • Salido M, Gonzalez JL, Vilches J. Loss of mitochondrial membrane potential is inhibited by bombesin in etoposide-induced apoptosis in PC-3 prostate carcinoma cells. Mol. Cancer Ther. 2007; 6: 1292-9.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 1292-1299
    • Salido, M.1    Gonzalez, J.L.2    Vilches, J.3
  • 41
    • 23244454378 scopus 로고    scopus 로고
    • Endothelin-1 inhibits apoptosis in prostate cancer
    • Nelson JB, Udan MS, Guruli G, Pflug BR. Endothelin-1 inhibits apoptosis in prostate cancer. Neoplasia. 2005; 7: 631-7.
    • (2005) Neoplasia. , vol.7 , pp. 631-637
    • Nelson, J.B.1    Udan, M.S.2    Guruli, G.3    Pflug, B.R.4
  • 42
    • 34248584876 scopus 로고    scopus 로고
    • In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer
    • Banerjee S, Hussain M, Wang Z etal. In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer. Cancer Res. 2007; 67: 3818-26.
    • (2007) Cancer Res. , vol.67 , pp. 3818-3826
    • Banerjee, S.1    Hussain, M.2    Wang, Z.3
  • 43
    • 0025940113 scopus 로고
    • Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles
    • Isaacs WB, Carter BS, Ewing CM. Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles. Cancer Res. 1991; 51: 4716-20.
    • (1991) Cancer Res. , vol.51 , pp. 4716-4720
    • Isaacs, W.B.1    Carter, B.S.2    Ewing, C.M.3
  • 45
    • 0037165631 scopus 로고    scopus 로고
    • A mutant P53 can activate apoptosis through a mechanism distinct from those induced by wild type P53
    • He M, Rennie PS, Dragowska V, Nelson CC, Jia W. A mutant P53 can activate apoptosis through a mechanism distinct from those induced by wild type P53. FEBS Lett. 2002; 517: 151-4.
    • (2002) FEBS Lett. , vol.517 , pp. 151-154
    • He, M.1    Rennie, P.S.2    Dragowska, V.3    Nelson, C.C.4    Jia, W.5
  • 46
    • 0038079838 scopus 로고    scopus 로고
    • Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells
    • Levine L, Lucci JA III, Pazdrak B etal. Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells. Cancer Res. 2003; 63: 3495-502.
    • (2003) Cancer Res. , vol.63 , pp. 3495-3502
    • Levine, L.1    Lucci III, J.A.2    Pazdrak, B.3
  • 47
    • 33751560243 scopus 로고    scopus 로고
    • Loss of neutral endopeptidase and activation of protein kinase B (Akt) is associated with prostate cancer progression
    • Osman I, Dai J, Mikhail M etal. Loss of neutral endopeptidase and activation of protein kinase B (Akt) is associated with prostate cancer progression. Cancer 2006; 107: 2628-36.
    • (2006) Cancer , vol.107 , pp. 2628-2636
    • Osman, I.1    Dai, J.2    Mikhail, M.3
  • 48
    • 27544494623 scopus 로고    scopus 로고
    • Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NF-kappaB activation
    • Kukreja P, Abdel-Mageed AB, Mondal D, Liu K, Agrawal KC. Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NF-kappaB activation. Cancer Res. 2005; 65: 9891-8.
    • (2005) Cancer Res. , vol.65 , pp. 9891-9898
    • Kukreja, P.1    Abdel-Mageed, A.B.2    Mondal, D.3    Liu, K.4    Agrawal, K.C.5
  • 49
    • 0035914390 scopus 로고    scopus 로고
    • PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression
    • Huang H, Cheville JC, Pan Y, Roche PC, Schmidt LJ, Tindall DJ. PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression. J. Biol. Chem. 2001; 276: 38830-6.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38830-38836
    • Huang, H.1    Cheville, J.C.2    Pan, Y.3    Roche, P.C.4    Schmidt, L.J.5    Tindall, D.J.6
  • 50
    • 33947196412 scopus 로고    scopus 로고
    • Phase I/II study of bortezomib plus docetaxel in patients with advanced androgen-independent prostate cancer
    • Dreicer R, Petrylak D, Agus D, Webb I, Roth B. Phase I/II study of bortezomib plus docetaxel in patients with advanced androgen-independent prostate cancer. Clin. Cancer Res. 2007; 13: 1208-15.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 1208-1215
    • Dreicer, R.1    Petrylak, D.2    Agus, D.3    Webb, I.4    Roth, B.5
  • 51
    • 34249910962 scopus 로고    scopus 로고
    • Weekly docetaxel and bortezomib as first-line treatment for patients with hormone-refractory prostate cancer: a Minnie Pearl Cancer Research Network phase II trial
    • Hainsworth JD, Meluch AA, Spigel DR etal. Weekly docetaxel and bortezomib as first-line treatment for patients with hormone-refractory prostate cancer: a Minnie Pearl Cancer Research Network phase II trial. Clin. Genitourin. Cancer 2007; 5: 278-83.
    • (2007) Clin. Genitourin. Cancer , vol.5 , pp. 278-283
    • Hainsworth, J.D.1    Meluch, A.A.2    Spigel, D.R.3
  • 52
    • 35948969806 scopus 로고    scopus 로고
    • A phase II trial of bortezomib and prednisone for castration resistant metastatic prostate cancer
    • Morris MJ, Kelly WK, Slovin S etal. A phase II trial of bortezomib and prednisone for castration resistant metastatic prostate cancer. J. Urol. 2007; 178: 2378-83.
    • (2007) J. Urol. , vol.178 , pp. 2378-2383
    • Morris, M.J.1    Kelly, W.K.2    Slovin, S.3


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