Up regulated complement and Fc receptors in juvenile idiopathic arthritis and correlation with disease phenotype

Journal of Clinical Immunology

Volumn 32, Issue 3, 2012, Pages 540-550

  Prokopec, Kajsa E ^a,b   Berntson, Lillemor ^a   Öman, Anders ^a   Kleinau, Sandra ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

B cells; complement; Fc receptors; Juvenile idiopathic arthritis; monocytes

Indexed keywords

C REACTIVE PROTEIN; CD16 ANTIGEN; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT RECEPTOR; COMPLEMENT RECEPTOR TYPE 2; FC GAMMA RECEPTOR I; FC GAMMA RECEPTOR II; FC RECEPTOR; FC RECEPTOR IIB; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG;

ADOLESCENT; ARTICLE; B LYMPHOCYTE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; JUVENILE RHEUMATOID ARTHRITIS; LYMPHOCYTE COUNT; MALE; MONOCYTE; OLIGOARTICULAR JUVENILE IDIOPATHIC ARTHRITIS; PHENOTYPE; POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SCHOOL CHILD;

ADOLESCENT; ARTHRITIS, JUVENILE RHEUMATOID; B-LYMPHOCYTES; C-REACTIVE PROTEIN; CHILD; CHILD, PRESCHOOL; COMPLEMENT C3; FEMALE; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INFANT; LEUKOCYTES, MONONUCLEAR; MALE; PHENOTYPE; RECEPTORS, COMPLEMENT 3B; RECEPTORS, COMPLEMENT 3D; RECEPTORS, FC; UP-REGULATION;

EID: 84861480362     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-012-9657-4     Document Type: Article

References (33)

1. Petty RE, Southwood TR, Manners P, Baum J, Glass DN, Goldenberg J, et al. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J Rheumatol. 2004;31(2):390-2. (Pubitemid 38160763)
2. Berntson L, Andersson Gare B, Fasth A, Herlin T, Kristinsson J, Lahdenne P, et al. Incidence of juvenile idiopathic arthritis in the Nordic countries. A population based study with special reference to the validity of the ILAR and EULAR criteria. J Rheumatol. 2003;30(10):2275-82. (Pubitemid 37221864)
3. Habib HM, Mosaad YM, Youssef HM. Anti-cyclic citrullinated peptide antibodies in patients with juvenile idiopathic arthritis. Immunol Invest. 2008;37(8):849-57.
4. Modesto C, Anton J, Rodriguez B, Bou R, Arnal C, Ros J, et al. Incidence and prevalence of juvenile idiopathic arthritis in Catalonia (Spain). Scand J Rheumatol. 39(6):472-9.
5. Pruunsild C, Uibo K, Liivamagi H, Tarraste S, Talvik T, Pelkonen P. Incidence of juvenile idiopathic arthritis in children in Estonia: a prospective population-based study. Scand J Rheumatol. 2007;36(1):7-13. (Pubitemid 46578065)
6. Low JM, Chauhan AK, Kietz DA, Daud U, Pepmueller PH, Moore TL. Determination of anti-cyclic citrullinated peptide antibodies in the sera of patients with juvenile idiopathic arthritis. J Rheumatol. 2004;31(9):1829-33. (Pubitemid 39202529)
7. Dewint P, Hoffman IE, Rogge S, Joos R, Union A, Dehoorne J, et al. Effect of age on prevalence of anticitrullinated protein/peptide antibodies in polyarticular juvenile idiopathic arthritis. Rheumatology (Oxford). 2006;45(2):204-8. (Pubitemid 43160086)
8. Tsokos GC, Inghirami G, Pillemer SR, Mavridis A, Magilavy DB. Immunoregulatory aberrations in patients with polyarticular juvenile rheumatoid arthritis. Clin Immunol Immunopathol. 1988;47(1):62-74.
9. Moore TL, Weiss TD. Immunologic studies in juvenile arthritis. Bull Rheum Dis. 1982;32(3):25-9. (Pubitemid 13249228)
10. Low JM, Chauhan AK, Moore TL. Abnormal kappa:lambda light chain ratio in circulating immune complexes as a marker for B cell activity in juvenile idiopathic arthritis. Scand J Immunol. 2007;65(1):76-83. (Pubitemid 44968075)
11. Kleinau S, Martinsson P, Heyman B. Induction and suppression of collagen-induced arthritis is dependent on distinct fcgamma receptors. J Exp Med. 2000;191(9):1611-6. (Pubitemid 30257357)
12. Kleinau S. The impact of Fc receptors on the development of autoimmune diseases. Curr Pharm Des. 2003;9(23):1861-70. (Pubitemid 37010089)
13. Torsteinsdottir I, Arvidson NG, Hallgren R, Hakansson L. Monocyte activation in rheumatoid arthritis (RA): increased integrin, Fc gamma and complement receptor expression and the effect of glucocorticoids. Clin Exp Immunol. 1999;115(3):554-60. (Pubitemid 29130375)
14. Hepburn AL, Mason JC, Davies KA. Expression of Fcgamma and complement receptors on peripheral blood monocytes in systemic lupus erythematosus and rheumatoid arthritis. Rheumatology (Oxford). 2004;43(5):547-54. (Pubitemid 38628182)
15. Magnusson SE, Engstrom M, Jacob U, Ulfgren AK, Kleinau S. High synovial expression of the inhibitory FcgammaRIIb in rheumatoid arthritis. Arthritis Res Ther. 2007;9(3):R51.
16. Prokopec KE, Rhodiner M, Matt P, Lindqvist U, Kleinau S. Down regulation of Fc and complement receptors on B cells in rheumatoid arthritis. Clin Immunol. 137(3):322-9.
17. Miller 3rd JJ, Olds LC, Huene DB. Complement activation products and factors influencing phagocyte migration in synovial fluids from children with chronic arthritis. Clin Exp Rheumatol. 1986;4(1):53-6. (Pubitemid 16166424)
18. Mollnes TE, Paus A. Complement activation in synovial fluid and tissue from patients with juvenile rheumatoid arthritis. Arthritis Rheum. 1986;29(11):1359-64. (Pubitemid 17214036)
19. Aggarwal A, Bhardwaj A, Alam S, Misra R. Evidence for activation of the alternate complement pathway in patients with juvenile rheumatoid arthritis. Rheumatology (Oxford). 2000;39(2):189-92. (Pubitemid 30139354)
20. Khera R, Das N. Complement receptor 1: disease associations and therapeutic implications. Mol Immunol. 2009;46(5):761-72.
21. Carter RH, Fearon DT. Polymeric C3dg primes human B lymphocytes for proliferation induced by anti-IgM. J Immunol. 1989;143(6):1755-60. (Pubitemid 19241184)
22. Dempsey PW, Allison ME, Akkaraju S, Goodnow CC, Fearon DT. C3d of complement as a molecular adjuvant: bridging innate and acquired immunity. Science. 1996;271(5247):348-50.
23. Bharadwaj D, Stein MP, Volzer M, Mold C, Du Clos TW. The major receptor for C-reactive protein on leukocytes is fcgamma receptor II. J Exp Med. 1999;190(4):585-90. (Pubitemid 29395386)
24. Lu J, Marnell LL, Marjon KD, Mold C, Du Clos TW, Sun PD. Structural recognition and functional activation of FcgammaR by innate pentraxins. Nature. 2008;456(7224):989-92.
25. Griffin TA, Barnes MG, Ilowite NT, Olson JC, Sherry DD, Gottlieb BS, et al. Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets. Arthritis Rheum. 2009;60(7):2113-23.
26. Ehlenberger AG, Nussenzweig V. The role of membrane receptors for C3b and C3d in phagocytosis. J Exp Med. 1977;145(2):357-71. (Pubitemid 8032091)
27. Liu D, Niu ZX. The structure, genetic polymorphisms, expression and biological functions of complement receptor type 1 (CR1/CD35). Immunopharmacol Immunotoxicol. 2009;31(4):524-35.
28. McCarthy D, Taylor MJ, Bernhagen J, Perry JD, Hamblin AS. Leucocyte integrin and CR1 expression on peripheral blood leucocytes of patients with rheumatoid arthritis. Ann Rheum Dis. 1992;51(3):307-12.
29. Barnes MG, Grom AA, Thompson SD, Griffin TA, Pavlidis P, Itert L, et al. Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis. Arthritis Rheum. 2009;60(7):2102-12.
30. Isaak A, Gergely Jr P, Szekeres Z, Prechl J, Poor G, Erdei A, et al. Physiological up-regulation of inhibitory receptors Fc gamma RII and CR1 on memory B cells is lacking in SLE patients. Int Immunol. 2008;20(2):185-92. (Pubitemid 351234385)
31. Martin U, Bock D, Arseniev L, Tornetta MA, Ames RS, BautschW, et al. The human C3a receptor is expressed on neutrophils andmonocytes, but not on B or T lymphocytes. J Exp Med. 1997;186(2):199-207. (Pubitemid 27328020)
32. Funkhouser TA, Vik DP. Complement receptor type 1 gene regulation: retinoic acid and cytosine arabinoside increase CR1 expression. Scand J Immunol. 1999;49(1):21-8. (Pubitemid 29052433)
33. Honczarenko M, Ratajczak MZ, Nicholson-Weller A, Silberstein LE. Complement C3a enhances CXCL12 (SDF-1)-mediated chemotaxis of bone marrow hematopoietic cells independently of C3a receptor. J Immunol. 2005;175(6):3698-706. (Pubitemid 41294509)