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Volumn 12, Issue , 2012, Pages 3-24

Using zebrafish to unravel the genetics of complex brain disorders

Author keywords

Alcoholism; Fear and anxiety; Fetal alcohol syndrome; High throughput behavioral screening; Learning and memory; Zebrafish

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MICRORNA; MORPHOLINO OLIGONUCLEOTIDE;

EID: 84861458112     PISSN: 18663370     EISSN: 18663389     Source Type: Book Series    
DOI: 10.1007/7854_2011_180     Document Type: Article
Times cited : (78)

References (67)
  • 1
    • 40849106321 scopus 로고    scopus 로고
    • Conspecifics as reward in associative learning tasks for zebrafish (Danio rerio)
    • Al-Imari L, Gerlai R (2008) Conspecifics as reward in associative learning tasks for zebrafish (Danio rerio). Behav Brain Res 189: 216-219
    • (2008) Behav Brain Res , vol.189 , pp. 216-219
    • Al-Imari, L.1    Gerlai, R.2
  • 2
    • 40449091409 scopus 로고    scopus 로고
    • Development of the corticosteroid stress axis and receptor expression in zebrafish
    • Alsop D, Vijayan MM (2008) Development of the corticosteroid stress axis and receptor expression in zebrafish. Am J Physiol Regul Integr Comp Physiol 294: R711-R719
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294 , pp. R711-R719
    • Alsop, D.1    Vijayan, M.M.2
  • 3
    • 33747173376 scopus 로고    scopus 로고
    • Mutagenesis strategies in zebrafish for identifying genes involved in development and disease
    • Amsterdam A, Hopkins N (2006) Mutagenesis strategies in zebrafish for identifying genes involved in development and disease. Trends Genet 22: 473-478
    • (2006) Trends Genet , vol.22 , pp. 473-478
    • Amsterdam, A.1    Hopkins, N.2
  • 4
    • 41349094144 scopus 로고    scopus 로고
    • Synaptic remodeling, synaptic growth and the storage of long-term memory in Aplysia
    • Bailey CH, Kandel ER (2008) Synaptic remodeling, synaptic growth and the storage of long-term memory in Aplysia. Prog Brain Res 169: 179-198
    • (2008) Prog Brain Res , vol.169 , pp. 179-198
    • Bailey, C.H.1    Kandel, E.R.2
  • 5
    • 77955845842 scopus 로고    scopus 로고
    • Genetic zebrafish models of neurodegenerative diseases
    • Bandmann O, Burton EA (2010) Genetic zebrafish models of neurodegenerative diseases. Neurobiol Dis 40: 58-65
    • (2010) Neurobiol Dis , vol.40 , pp. 58-65
    • Bandmann, O.1    Burton, E.A.2
  • 6
    • 36049024852 scopus 로고    scopus 로고
    • Zebrafish (Danio rerio) responds differentially to stimulus fish: The effects of sympatric and allopatric predators and harmless fish
    • Bass SLS, Gerlai R (2008) Zebrafish (Danio rerio) responds differentially to stimulus fish: the effects of sympatric and allopatric predators and harmless fish. Behav Brain Res 186: 107-117
    • (2008) Behav Brain Res , vol.186 , pp. 107-117
    • Bass, S.L.S.1    Gerlai, R.2
  • 8
    • 33846488806 scopus 로고    scopus 로고
    • Behavioral phenotyping in zebrafish: Comparison of three behavioral quantification methods
    • Blaser R, Gerlai R (2006) Behavioral phenotyping in zebrafish: comparison of three behavioral quantification methods. Behav Res Meth 38: 456-469
    • (2006) Behav Res Meth , vol.38 , pp. 456-469
    • Blaser, R.1    Gerlai, R.2
  • 9
    • 0035870801 scopus 로고    scopus 로고
    • Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia
    • Braff DL, Geyer MA, Light GA, Sprock J, Perry W, Cadenhead KS et al (2001) Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia. Schizophr Res 49: 171-178
    • (2001) Schizophr Res , vol.49 , pp. 171-178
    • Braff, D.L.1    Geyer, M.A.2    Light, G.A.3    Sprock, J.4    Perry, W.5    Cadenhead, K.S.6
  • 10
    • 34247857650 scopus 로고    scopus 로고
    • Sensorimotor gating in larval zebrafish
    • Burgess HA, Granato M (2007) Sensorimotor gating in larval zebrafish. J Neurosci 27: 4984-4994
    • (2007) J Neurosci , vol.27 , pp. 4984-4994
    • Burgess, H.A.1    Granato, M.2
  • 11
    • 0024328536 scopus 로고
    • Altering the genome by homologous recombination
    • Capecchi MR (1989) Altering the genome by homologous recombination. Science 244: 1288-1292
    • (1989) Science , vol.244 , pp. 1288-1292
    • Capecchi, M.R.1
  • 12
    • 62649166825 scopus 로고    scopus 로고
    • High precision liquid chromatography analysis of dopaminergic and serotoninergic responses to acute alcohol exposure in zebrafish
    • Chatterjee D, Gerlai R (2009) High precision liquid chromatography analysis of dopaminergic and serotoninergic responses to acute alcohol exposure in zebrafish. Behav Brain Res 200: 208-213
    • (2009) Behav Brain Res , vol.200 , pp. 208-213
    • Chatterjee, D.1    Gerlai, R.2
  • 13
    • 4844220944 scopus 로고    scopus 로고
    • Zebrafish as a genomics research model
    • Chen E, Ekker SC (2004) Zebrafish as a genomics research model. Curr Pharm Biotechnol 5: 409-413
    • (2004) Curr Pharm Biotechnol , vol.5 , pp. 409-413
    • Chen, E.1    Ekker, S.C.2
  • 14
    • 0030634171 scopus 로고    scopus 로고
    • Memory for items and memory for relations in the procedural/declarative memory framework
    • Cohen NJ, Poldrack RA, Eichenbaum H (1997) Memory for items and memory for relations in the procedural/declarative memory framework. Memory 5: 131-178
    • (1997) Memory , vol.5 , pp. 131-178
    • Cohen, N.J.1    Poldrack, R.A.2    Eichenbaum, H.3
  • 15
    • 65449152259 scopus 로고    scopus 로고
    • Structural and functional evolution of vertebrate neuroendocrine stress systems
    • Denver RJ (2009) Structural and functional evolution of vertebrate neuroendocrine stress systems. Ann N Y Acad Sci 1163: 1-16
    • (2009) Ann N Y Acad Sci , vol.1163 , pp. 1-16
    • Denver, R.J.1
  • 16
    • 69049098972 scopus 로고    scopus 로고
    • Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation
    • Drerup CM, Wiora HM, Topczewski J, Morris JA (2009) Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation. Development 136: 2623-2632
    • (2009) Development , vol.136 , pp. 2623-2632
    • Drerup, C.M.1    Wiora, H.M.2    Topczewski, J.3    Morris, J.A.4
  • 18
    • 45549086423 scopus 로고    scopus 로고
    • Zinc finger-based knockout punches for zebrafish genes
    • Ekker SC (2008) Zinc finger-based knockout punches for zebrafish genes. Zebrafish 5: 121-123
    • (2008) Zebrafish , vol.5 , pp. 121-123
    • Ekker, S.C.1
  • 19
    • 34247527825 scopus 로고    scopus 로고
    • Zebrafish in the wild: A review of natural history and new notes from the field
    • Engeszer RE, Patterson LB, Rao AA, Parichy DM (2007) Zebrafish in the wild: a review of natural history and new notes from the field. Zebrafish 4: 21-40
    • (2007) Zebrafish , vol.4 , pp. 21-40
    • Engeszer, R.E.1    Patterson, L.B.2    Rao, A.A.3    Parichy, D.M.4
  • 20
    • 33846058768 scopus 로고    scopus 로고
    • Zebrafish embryonic stem cells
    • Fan L, Collodi P (2006) Zebrafish embryonic stem cells. Methods Enzymol 418: 64-77
    • (2006) Methods Enzymol , vol.418 , pp. 64-77
    • Fan, L.1    Collodi, P.2
  • 21
    • 77952374703 scopus 로고    scopus 로고
    • De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia
    • Gauthier J, Champagne N, Lafreniere RG, Xiong L, Spiegelman D, Brustein E et al (2010) De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proc Natl Acad Sci USA 107: 7863-7868
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 7863-7868
    • Gauthier, J.1    Champagne, N.2    Lafreniere, R.G.3    Xiong, L.4    Spiegelman, D.5    Brustein, E.6
  • 22
    • 74449086692 scopus 로고    scopus 로고
    • Zebrafish antipredatory responses: A future for translational research
    • (in press)
    • Gerlai R (2010) Zebrafish antipredatory responses: a future for translational research? Behav Brain Res (in press)
    • (2010) Behav Brain Res
    • Gerlai, R.1
  • 23
    • 0036775142 scopus 로고    scopus 로고
    • Phenomics: Fiction or the future?
    • Gerlai R (2002) Phenomics: fiction or the future? Trends Neurosci 25: 506-509
    • (2002) Trends Neurosci , vol.25 , pp. 506-509
    • Gerlai, R.1
  • 24
    • 0042884430 scopus 로고    scopus 로고
    • Autism: A large unmet medical need and a complex research problem
    • Gerlai J, Gerlai R (2003) Autism: a large unmet medical need and a complex research problem. Physiol Behav 79: 461-470
    • (2003) Physiol Behav , vol.79 , pp. 461-470
    • Gerlai, J.1    Gerlai, R.2
  • 25
    • 0033082436 scopus 로고    scopus 로고
    • Analysing hippocampal function in transgenic mice: An ethological perspective
    • Gerlai R, Clayton NS (1999) Analysing hippocampal function in transgenic mice: an ethological perspective. Trends Neurosci 22: 47-51
    • (1999) Trends Neurosci , vol.22 , pp. 47-51
    • Gerlai, R.1    Clayton, N.S.2
  • 26
    • 68249084619 scopus 로고    scopus 로고
    • Acute and chronic alcohol dose: Population differences in behavior and neurochemistry of zebrafish
    • Gerlai R, Chatterjee D, Pereira T, Sawashima T, Krishnannair R (2009a) Acute and chronic alcohol dose: population differences in behavior and neurochemistry of zebrafish. Genes Brain Behav 8: 586-599
    • (2009) Genes Brain Behav , vol.8 , pp. 586-599
    • Gerlai, R.1    Chatterjee, D.2    Pereira, T.3    Sawashima, T.4    Krishnannair, R.5
  • 27
    • 67349202870 scopus 로고    scopus 로고
    • Zebrafish (Danio rerio) responds to the animated image of a predator: Towards the development of an automated aversive task
    • Gerlai R, Fernandes Y, Pereira T (2009b) Zebrafish (Danio rerio) responds to the animated image of a predator: towards the development of an automated aversive task. Behav Brain Res 201: 318-324
    • (2009) Behav Brain Res , vol.201 , pp. 318-324
    • Gerlai, R.1    Fernandes, Y.2    Pereira, T.3
  • 28
    • 0029170918 scopus 로고
    • Over-expression of a calcium binding protein, S100ß, in astrocytes alters synaptic plasticity and impairs spatial learning in transgenic mice
    • Gerlai R, Wojtowicz JM, Marks A, Roder J (1995) Over-expression of a calcium binding protein, S100ß, in astrocytes alters synaptic plasticity and impairs spatial learning in transgenic mice. Learn Mem 2: 26-39
    • (1995) Learn Mem , vol.2 , pp. 26-39
    • Gerlai, R.1    Wojtowicz, J.M.2    Marks, A.3    Roder, J.4
  • 29
    • 67349236400 scopus 로고    scopus 로고
    • Behavioral and genetic characterization of habituation using Caenorhabditis elegans
    • Giles AC, Rankin CH (2009) Behavioral and genetic characterization of habituation using Caenorhabditis elegans. Neurobiol Learn Mem 92: 139-146
    • (2009) Neurobiol Learn Mem , vol.92 , pp. 139-146
    • Giles, A.C.1    Rankin, C.H.2
  • 30
    • 77249094974 scopus 로고    scopus 로고
    • Latent Learning in Zebrafish (Danio rerio)
    • Gómez-Laplaza LM, Gerlai R (2010) Latent Learning in Zebrafish (Danio rerio). Behav Brain Res 208: 509-515
    • (2010) Behav Brain Res , vol.208 , pp. 509-515
    • Gómez-Laplaza, L.M.1    Gerlai, R.2
  • 31
    • 0029925636 scopus 로고    scopus 로고
    • Large scale genetics in a small vertebrate, the zebrafish
    • Haffter P, Nüsslein-Volhard C (1996) Large scale genetics in a small vertebrate, the zebrafish. Int J Dev Biol 40: 221-227
    • (1996) Int J Dev Biol , vol.40 , pp. 221-227
    • Haffter, P.1    Nüsslein-Volhard, C.2
  • 33
    • 22244433819 scopus 로고    scopus 로고
    • Conditional expression of a myocardium-specific transgene in zebrafish transgenic lines
    • Huang CJ, Jou TS, Ho YL, Lee WH, Jeng YT, Hsieh FJ, Tsai HJ (2005) Conditional expression of a myocardium-specific transgene in zebrafish transgenic lines. Dev Dyn 233: 1294-1303
    • (2005) Dev Dyn , vol.233 , pp. 1294-1303
    • Huang, C.J.1    Jou, T.S.2    Ho, Y.L.3    Lee, W.H.4    Jeng, Y.T.5    Hsieh, F.J.6    Tsai, H.J.7
  • 34
    • 70349786368 scopus 로고    scopus 로고
    • Amyloid precursor protein is required for convergent-extension movements during zebrafish development
    • Joshi P, Liang JO, Dimonte K, Sullivan J, Pimplikar SW (2009) Amyloid precursor protein is required for convergent-extension movements during zebrafish development. Dev Biol 335: 1-11
    • (2009) Dev Biol , vol.335 , pp. 1-11
    • Joshi, P.1    Liang, J.O.2    Dimonte, K.3    Sullivan, J.4    Pimplikar, S.W.5
  • 35
    • 76849106258 scopus 로고    scopus 로고
    • Vivo-Morpholino knockdown of alpha IIb: A novel approach to inhibit thrombocyte function in adult zebrafish
    • Kim S, Radhakrishnan UP, Rajpurohit SK, Kulkarni V, Jagadeeswaran P (2010) Vivo-Morpholino knockdown of alpha IIb: a novel approach to inhibit thrombocyte function in adult zebrafish. Blood Cells Mol Dis 44: 169-174
    • (2010) Blood Cells Mol Dis , vol.44 , pp. 169-174
    • Kim, S.1    Radhakrishnan, U.P.2    Rajpurohit, S.K.3    Kulkarni, V.4    Jagadeeswaran, P.5
  • 36
    • 0033862087 scopus 로고    scopus 로고
    • ENU mutagenesis in zebrafish-from genes to complex diseases
    • Knapik EW (2000) ENU mutagenesis in zebrafish-from genes to complex diseases. Mamm Genome 11: 511-519
    • (2000) Mamm Genome , vol.11 , pp. 511-519
    • Knapik, E.W.1
  • 37
    • 17844403755 scopus 로고    scopus 로고
    • Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia
    • Langenau DM, Feng H, Berghmans S, Kanki JP, Kutok JL, Look AT (2005) Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia. Proc Natl Acad Sci USA 102: 6068-6073
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 6068-6073
    • Langenau, D.M.1    Feng, H.2    Berghmans, S.3    Kanki, J.P.4    Kutok, J.L.5    Look, A.T.6
  • 38
    • 0036022515 scopus 로고    scopus 로고
    • Cloned zebrafish by nuclear transfer from longterm-cultured cells
    • Lee KY, Huang H, Ju B, Yang Z, Lin S (2002) Cloned zebrafish by nuclear transfer from longterm-cultured cells. Nat Biotech 20: 795-799
    • (2002) Nat Biotech , vol.20 , pp. 795-799
    • Lee, K.Y.1    Huang, H.2    Ju, B.3    Yang, Z.4    Lin, S.5
  • 40
    • 77955847027 scopus 로고    scopus 로고
    • Use of zebrafish as a model to understand mechanisms of addiction and complex neurobehavioral phenotypes
    • Mathur P, Guo S (2010) Use of zebrafish as a model to understand mechanisms of addiction and complex neurobehavioral phenotypes. Neurobiol Dis 40: 66-72
    • (2010) Neurobiol Dis , vol.40 , pp. 66-72
    • Mathur, P.1    Guo, S.2
  • 41
    • 0032872568 scopus 로고    scopus 로고
    • Hippocampal encoding of non-spatial trace conditioning
    • McEchron MD, Disterhoft JF (1999) Hippocampal encoding of non-spatial trace conditioning. Hippocampus 9: 385-396
    • (1999) Hippocampus , vol.9 , pp. 385-396
    • McEchron, M.D.1    Disterhoft, J.F.2
  • 42
    • 47849111018 scopus 로고    scopus 로고
    • Oscillations in shoal cohesion in zebrafish (Danio rerio)
    • Miller N, Gerlai R (2008) Oscillations in shoal cohesion in zebrafish (Danio rerio). Behav. Brain Res 193: 148-151
    • (2008) Behav Brain Res , vol.193 , pp. 148-151
    • Miller, N.1    Gerlai, R.2
  • 43
    • 34848916041 scopus 로고    scopus 로고
    • Quantification of shoaling behaviour in zebrafish (Danio rerio)
    • Miller N, Gerlai R (2007) Quantification of shoaling behaviour in zebrafish (Danio rerio). Behav. Brain Res 184: 157-166
    • (2007) Behav Brain Res , vol.184 , pp. 157-166
    • Miller, N.1    Gerlai, R.2
  • 46
    • 70349774255 scopus 로고    scopus 로고
    • The synthetic substance hypoxanthine 3-N-oxide elicits alarm reactions in zebrafish (Danio rerio). Behav
    • Parra KV, Adrian JC Jr, Gerlai R (2009) The synthetic substance hypoxanthine 3-N-oxide elicits alarm reactions in zebrafish (Danio rerio). Behav. Brain Res 205: 336-341
    • (2009) Brain Res , vol.205 , pp. 336-341
    • Parra, K.V.1    Adrian, J.C.2    Gerlai, R.3
  • 47
    • 66449115032 scopus 로고    scopus 로고
    • A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation
    • Paquet D et al (2009) A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation. J Clin Invest 119: 1382-1395
    • (2009) J Clin Invest , vol.119 , pp. 1382-1395
    • Paquet, D.1
  • 48
    • 57549103403 scopus 로고    scopus 로고
    • Shuttle box learning in zebrafish
    • Pather S, Gerlai R (2009) Shuttle box learning in zebrafish. Behav Brain Res 196: 323-327
    • (2009) Behav Brain Res , vol.196 , pp. 323-327
    • Pather, S.1    Gerlai, R.2
  • 49
    • 0035657098 scopus 로고    scopus 로고
    • The art and design of genetic screens: Zebrafish
    • Patton EE, Zon LI (2001) The art and design of genetic screens: zebrafish. Nat Rev Genet 2: 956-966
    • (2001) Nat Rev Genet , vol.2 , pp. 956-966
    • Patton, E.E.1    Zon, L.I.2
  • 52
    • 4644283280 scopus 로고    scopus 로고
    • Two zebrafi sh alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V alcohol dehydrogenase genes but have distinct functional characteristics
    • Reimers MJ, Hahn ME, Tanguay RL (2004) Two zebrafi sh alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V alcohol dehydrogenase genes but have distinct functional characteristics. J Biol Chem; 279: 38303-38312
    • (2004) J Biol Chem , vol.279 , pp. 38303-38312
    • Reimers, M.J.1    Hahn, M.E.2    Tanguay, R.L.3
  • 54
    • 0029907161 scopus 로고    scopus 로고
    • Spatial learning and memory deficits after telencephalic ablation in goldfish trained in place and turn maze procedures
    • Salas C, Rodríguez F, Vargas JP, Durán E, Torres B (1996) Spatial learning and memory deficits after telencephalic ablation in goldfish trained in place and turn maze procedures. Behav Neurosci 110: 965-980
    • (1996) Behav Neurosci , vol.110 , pp. 965-980
    • Salas, C.1    Rodríguez, F.2    Vargas, J.P.3    Durán, E.4    Torres, B.5
  • 56
    • 70649107814 scopus 로고    scopus 로고
    • Associative learning in zebrafish (Danio rerio) in the plus maze
    • Sison M, Gerlai R (2010) Associative learning in zebrafish (Danio rerio) in the plus maze. Behav Brain Res 207: 99-104
    • (2010) Behav Brain Res , vol.207 , pp. 99-104
    • Sison, M.1    Gerlai, R.2
  • 57
    • 33745631554 scopus 로고    scopus 로고
    • Fishing for genes of vertebrate behavior: Zebra fish as an upcoming model system
    • Sison M, Cawker J, Buske C, Gerlai R (2006) Fishing for genes of vertebrate behavior: zebra fish as an upcoming model system. Lab Animal 35: 33-39
    • (2006) Lab Animal , vol.35 , pp. 33-39
    • Sison, M.1    Cawker, J.2    Buske, C.3    Gerlai, R.4
  • 59
    • 42149116360 scopus 로고    scopus 로고
    • Current perspectives in zebrafish reverse genetics: Moving forward
    • Skromne I, Prince VE (2008) Current perspectives in zebrafish reverse genetics: moving forward. Dev Dyn 237: 861-882
    • (2008) Dev Dyn , vol.237 , pp. 861-882
    • Skromne, I.1    Prince, V.E.2
  • 60
    • 0035515462 scopus 로고    scopus 로고
    • Drosophila: Genetics meets behaviour
    • Sokolowski MB (2001) Drosophila: genetics meets behaviour. Nat Rev Genet 2: 879-890
    • (2001) Nat Rev Genet , vol.2 , pp. 879-890
    • Sokolowski, M.B.1
  • 61
    • 38749106264 scopus 로고    scopus 로고
    • Alarm substance induced behavioral responses in zebrafish (Danio rerio) Behav
    • Speedie N, Gerlai R (2008) Alarm substance induced behavioral responses in zebrafish (Danio rerio) Behav. Brain Res 188: 168-177
    • (2008) Brain Res , vol.188 , pp. 168-177
    • Speedie, N.1    Gerlai, R.2
  • 62
    • 85013689080 scopus 로고    scopus 로고
    • 2nd edn, Elsevier, Amsterdam
    • Sweatt JD (2010) Mechanisms of memory. 2nd edn, Elsevier, Amsterdam, p 343
    • (2010) Mechanisms of memory , pp. 343
    • Sweatt, J.D.1
  • 63
    • 77956524118 scopus 로고    scopus 로고
    • Production of p53 gene knockout rats by homologous recombination in embryonic stem cells
    • Tong C, Li P, Wu NL, Yan Y, Ying QL (2010) Production of p53 gene knockout rats by homologous recombination in embryonic stem cells. Nature 467: 211-213
    • (2010) Nature , vol.467 , pp. 211-213
    • Tong, C.1    Li, P.2    Wu, N.L.3    Yan, Y.4    Ying, Q.L.5
  • 64
    • 0242291084 scopus 로고    scopus 로고
    • Can zebrafish be used as a model to study the neurodevelopmental causes of autism?
    • Tropepe V, Sive HL (2003) Can zebrafish be used as a model to study the neurodevelopmental causes of autism? Genes Brain Behav 2: 268-281
    • (2003) Genes Brain Behav , vol.2 , pp. 268-281
    • Tropepe, V.1    Sive, H.L.2
  • 66
    • 70349232832 scopus 로고    scopus 로고
    • Overview of generalized anxiety disorder: Epidemiology, presentation, and course
    • Weisberg RB (2009) Overview of generalized anxiety disorder: epidemiology, presentation, and course. J Clin Psychiatry 70(Suppl 2): 4-9
    • (2009) J Clin Psychiatry , vol.70 , pp. 4-9
    • Weisberg, R.B.1
  • 67
    • 77954548661 scopus 로고    scopus 로고
    • Exploring Alzheimer's disease in zebrafish
    • Xia W (2010) Exploring Alzheimer's disease in zebrafish. J Alzheimer's Dis 20: 981-990
    • (2010) J Alzheimer's Dis , vol.20 , pp. 981-990
    • Xia, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.