Intracellular metabolite profiling of platelets: Evaluation of extraction processes and chromatographic strategies

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 898, Issue , 2012, Pages 111-120

  Paglia, Giuseppe ^a   Magnúsdóttir, Manuela ^a   Thorlacius, Steinunn ^a   Sigurjónsson, Ólafur E ^b,c   Gudmundsson, Sveinn ^b   Palsson, Bernhard Ø ^a   Thiele, Ines ^a  

^a UNIVERSITY OF ICELAND   (Iceland)

^b LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^c REYKJAVIK UNIVERSITY   (Iceland)

Author keywords

Extraction; HILIC; Metabolomics; Platelets; Reversed phase liquid chromatography; UPLC MS

Indexed keywords

ANALYTICAL METHOD; ANALYTICAL PROTOCOLS; CELL EXTRACTS; EVALUATION CRITERIA; EXTRACTION METHOD; EXTRACTION PROCESS; HILIC; HILIC-MS; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHIES; INTRACELLULAR METABOLITES; LC-MS METHODS; METABOLITE ANALYSIS; METABOLOMES; METABOLOMICS; METHANOL-WATER; OPTIMAL CONDITIONS; PHYSICOCHEMICAL PROPERTY; REPRODUCIBILITIES; REVERSED PHASE LIQUID-CHROMATOGRAPHY; UPLC-MS;

CHEMICAL PROPERTIES; EXTRACTION; LIQUID CHROMATOGRAPHY; METABOLITES; METHANOL; OPTIMIZATION; PLATELETS;

BIOMOLECULES;

ACETONITRILE; CELL EXTRACT; CHLOROFORM; METHANOL; WATER;

ACIDITY; ALKALINITY; ANALYTICAL EQUIPMENT; ARTICLE; CONTROLLED STUDY; EXTRACTION; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; INTERMETHOD COMPARISON; LIQUID LIQUID EXTRACTION; MASS SPECTROMETER; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REPRODUCIBILITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLVENT EXTRACTION; TEMPERATURE; THROMBOCYTE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

BLOOD PLATELETS; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, LIQUID; HUMANS; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; METHANOL; PRINCIPAL COMPONENT ANALYSIS; REPRODUCIBILITY OF RESULTS; WATER;

EID: 84861458008     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.04.026     Document Type: Article

References (29)

1. Holmes E., Wilson I.D., Nicholson J.K. Cell 2008, 134:714.
2. Holmes E., Loo R.L., Stamler J., Bictash M., Yap I.K., Chan Q., Ebbels T., De Iorio M., Brown I.J., Veselkov K.A., Daviglus M.L., Kesteloot H., Ueshima H., Zhao L., Nicholson J.K., Elliott P. Nature 2008, 453:396.
3. Denkert C., Budczies J., Weichert W., Wohlgemuth G., Scholz M., Kind T., Niesporek S., Noske A., Buckendahl A., Dietel M., Fiehn O. Mol. Cancer 2008, 7:72.
4. Denkert C., Budczies J., Kind T., Weichert W., Tablack P., Sehouli J., Niesporek S., Konsgen D., Dietel M., Fiehn O. Cancer Res. 2006, 66:10795.
5. Clayton T.A., Lindon J.C., Cloarec O., Antti H., Charuel C., Hanton G., Provost J.P., Le Net J.L., Baker D., Walley R.J., Everett J.R., Nicholson J.K. Nature 2006, 440:1073.
6. Dunn W.B. Phys. Biol. 2008, 5:011001.
7. Pendyala G., Want E.J., Webb W., Siuzdak G., Fox H.S. J. Neuroimmune Pharmacol.: Off. J. Soc. NeuroImmune Pharmacol. 2007, 2:72.
8. Dunn W.B., Broadhurst D.I., Atherton H.J., Goodacre R., Griffin J.L. Chem. Soc. Rev. 2011, 40:387.
9. Dunn W.B., Broadhurst D., Begley P., Zelena E., Francis-McIntyre S., Anderson N., Brown M., Knowles J.D., Halsall A., Haselden J.N., Nicholls A.W., Wilson I.D., Kell D.B., Goodacre R. Nat. Protoc. 2011, 6:1060. Human Serum Metabolome Consortium.
10. Want E.J., Wilson I.D., Gika H., Theodoridis G., Plumb R.S., Shockcor J., Holmes E., Nicholson J.K. Nat. Protoc. 2010, 5:1005.
11. Yu Z.H., Kastenmuller G., He Y., Belcredi P., Moller G., Prehn C., Mendes J., Wahl S., Roemisch-Margl W., Ceglarek U., Polonikov A., Dahmen N., Prokisch H., Xie L., Li Y.X., Wichmann H.E., Peters A., Kronenberg F., Suhre K., Adamski J., Illig T., Wang-Sattler R. PLoS ONE 2011, 6.
12. Psychogios N., Hau D.D., Peng J., Guo A.C., Mandal R., Bouatra S., Sinelnikov I., Krishnamurthy R., Eisner R., Gautam B., Young N., Xia J.G., Knox C., Dong E., Huang P., Hollander Z., Pedersen T.L., Smith S.R., Bamforth F., Greiner R., McManus B., Newman J.W., Goodfriend T., Wishart D.S. PLoS ONE 2011, 6.
13. Werner E., Heilier J.F., Ducruix C., Ezan E., Junot C., Tabet J.C. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2008, 871:143.
14. Nevedomskaya E., Ramautar R., Derks R., Westbroek I., Zondag G., van der Pluijm I., Deelder A.M., Mayboroda O.A. J. Proteome Res. 2010, 9:4869.
15. Koek M.M., Bakels F., Engel W., van den Maagdenberg A., Ferrari M.D., Coulier L., Hankemeier T. Anal. Chem. 2010, 82:156.
16. Lu W., Bennett B.D., Rabinowitz J.D. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2008, 871:236.
17. Bennett B.D., Yuan J., Kimball E.H., Rabinowitz J.D. Nat. Protoc. 2008, 3:1299.
18. Ritter J.B., Genzel Y., Reichl U. Anal. Biochem. 2008, 373:349.
19. Sellick C.A., Knight D., Croxford A.S., Maqsood A.R., Stephens G.M., Goodacre R., Dickson A.J. Metabolomics 2010, 6:427.
20. Dietmair S., Timmins N.E., Gray P.P., Nielsen L.K., Kromer J.O. Anal. Biochem. 2010, 404:155.
21. Sellick C.A., Hansen R., Stephens G.M., Goodacre R., Dickson A.J. Nat. Protoc. 2011, 6:1241.
22. Sana T.R., Waddell K., Fischer S.M. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2008, 871:314.
23. Zhang Y., Jiye A., Wang G., Huang Q., Yan B., Zha W., Gu S., Liu L., Ren H., Ren M., Sheng L. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2009, 877:1751.
24. Ruggeri Z.M. Nat. Med. 2002, 8:1227.
25. Weyrich A.S., Lindemann S., Zimmerman G.A. J. Thromb. Haemost. 2003, 1:1897.
26. Schubert P., Devine D.V. Vox Sang. 2010, 99:112.
27. Oresic M., Tang J., Seppanen-Laakso T., Mattila I., Saarni S.E., Saarni S.I., Lonnqvist J., Sysi-Aho M., Hyotylainen T., Perala J., Suvisaari J. Genome Med. 2011, 3:19.
28. Spagou K., Wilson I.D., Masson P., Theodoridis G., Raikos N., Coen M., Holmes E., Lindon J.C., Plumb R.S., Nicholson J.K., Want E.J. Anal. Chem. 2011, 83:382.
29. Paglia G., Hrafnsdottir S., Magnusdottir M., Fleming R.M., Thorlacius S., Palsson B.O., Thiele I. Anal. Bioanal. Chem. 2012, 402:1183.