메뉴 건너뛰기




Volumn 79, Issue 1, 2012, Pages 82-84

HIF-1α/VEGF signaling pathway may play a dual role in secondary pathogenesis of cervical myelopathy

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ARACHIDONIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RECOMBINANT VASCULOTROPIN; VASCULOTROPIN; VASCULOTROPIN 165;

EID: 84861456201     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2012.04.006     Document Type: Article
Times cited : (20)

References (26)
  • 1
    • 0142248744 scopus 로고    scopus 로고
    • Cervical spondylotic myelopathy: make the difficult diagnosis, then refer for surgery
    • McCormick W.E., Steinmetz M.P., Benzel E.C. Cervical spondylotic myelopathy: make the difficult diagnosis, then refer for surgery. Cleve Clin J Med 2003, 70:899-904.
    • (2003) Cleve Clin J Med , vol.70 , pp. 899-904
    • McCormick, W.E.1    Steinmetz, M.P.2    Benzel, E.C.3
  • 2
    • 79957597549 scopus 로고    scopus 로고
    • Somatosensory-evoked potentials as an indicator for the extent of ultrastructural damage of the spinal cord after chronic compressive injuries in a rat model
    • Hu Y., Wen C.Y., Li T.H., Cheung M.M., Wu E.X., Luk K.D. Somatosensory-evoked potentials as an indicator for the extent of ultrastructural damage of the spinal cord after chronic compressive injuries in a rat model. Clin Neurophysiol 2011, 122(7):1440-1447.
    • (2011) Clin Neurophysiol , vol.122 , Issue.7 , pp. 1440-1447
    • Hu, Y.1    Wen, C.Y.2    Li, T.H.3    Cheung, M.M.4    Wu, E.X.5    Luk, K.D.6
  • 3
    • 39749188133 scopus 로고    scopus 로고
    • The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes
    • Vangeison G., Carr D., Federoff H.J., Rempe D.A. The good, the bad, and the cell type-specific roles of hypoxia inducible factor-1 alpha in neurons and astrocytes. J Neurosci 2008, 28(8):1988-1993.
    • (2008) J Neurosci , vol.28 , Issue.8 , pp. 1988-1993
    • Vangeison, G.1    Carr, D.2    Federoff, H.J.3    Rempe, D.A.4
  • 4
    • 0033435198 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain
    • Bergeron M., Yu A.Y., Solway K.E., Semenza G.L., Sharp F.R. Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur J Neurosci 1999, 11(12):4159-4170.
    • (1999) Eur J Neurosci , vol.11 , Issue.12 , pp. 4159-4170
    • Bergeron, M.1    Yu, A.Y.2    Solway, K.E.3    Semenza, G.L.4    Sharp, F.R.5
  • 5
    • 0042133340 scopus 로고    scopus 로고
    • Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury
    • Widenfalk J., Lipson A., Jubran M., et al. Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury. Neuroscience 2003, 120(4):951-960.
    • (2003) Neuroscience , vol.120 , Issue.4 , pp. 951-960
    • Widenfalk, J.1    Lipson, A.2    Jubran, M.3
  • 6
    • 63449139550 scopus 로고    scopus 로고
    • Ex vivo VEGF delivery by neural stem cells enhances proliferation of glial progenitors, angiogenesis, and tissue sparing after spinal cord injury
    • Kim H.M., Hwang D.H., Lee J.E., Kim S.U., Kim B.G. Ex vivo VEGF delivery by neural stem cells enhances proliferation of glial progenitors, angiogenesis, and tissue sparing after spinal cord injury. PLoS One 2009, 4:e4987.
    • (2009) PLoS One , vol.4
    • Kim, H.M.1    Hwang, D.H.2    Lee, J.E.3    Kim, S.U.4    Kim, B.G.5
  • 7
    • 0142116387 scopus 로고    scopus 로고
    • VEGF165 therapy exacerbates secondary damage following spinal cord injury
    • Benton R.L., Whittemore S.R. VEGF165 therapy exacerbates secondary damage following spinal cord injury. Neurochem Res 2003, 28(11):1693-1703.
    • (2003) Neurochem Res , vol.28 , Issue.11 , pp. 1693-1703
    • Benton, R.L.1    Whittemore, S.R.2
  • 8
    • 69249150412 scopus 로고    scopus 로고
    • Effect of VEGF treatment on the blood-spinal cord barrier permeability in experimental spinal cord injury: dynamic contrast-enhanced magnetic resonance imaging
    • Patel C.B., Cohen D.M., Ahobila-Vajjula P., Sundberg L.M., Chacko T., Narayana P.A. Effect of VEGF treatment on the blood-spinal cord barrier permeability in experimental spinal cord injury: dynamic contrast-enhanced magnetic resonance imaging. J Neurotrauma 2009, 26:1005-1016.
    • (2009) J Neurotrauma , vol.26 , pp. 1005-1016
    • Patel, C.B.1    Cohen, D.M.2    Ahobila-Vajjula, P.3    Sundberg, L.M.4    Chacko, T.5    Narayana, P.A.6
  • 9
    • 0029039195 scopus 로고
    • Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
    • Levy A.P., Levy N.S., Wegner S., Goldberg M.A. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J Biol Chem 1995, 270:13333-13340.
    • (1995) J Biol Chem , vol.270 , pp. 13333-13340
    • Levy, A.P.1    Levy, N.S.2    Wegner, S.3    Goldberg, M.A.4
  • 10
    • 0035910429 scopus 로고    scopus 로고
    • Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide
    • Kimura H., Weisz A., Ogura T., et al. Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide. J Biol Chem 2001, 276:2292-2298.
    • (2001) J Biol Chem , vol.276 , pp. 2292-2298
    • Kimura, H.1    Weisz, A.2    Ogura, T.3
  • 12
    • 0141861939 scopus 로고    scopus 로고
    • Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene
    • Murakami T., Ilieva H., Shiote M., et al. Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene. Brain Res 2003, 989:231-237.
    • (2003) Brain Res , vol.989 , pp. 231-237
    • Murakami, T.1    Ilieva, H.2    Shiote, M.3
  • 13
    • 2542474182 scopus 로고    scopus 로고
    • Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor
    • Nordal R.A., Nagy A., Pintilie M., Wong C.S. Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor. Clin Cancer Res 2004, 10:3342-3353.
    • (2004) Clin Cancer Res , vol.10 , pp. 3342-3353
    • Nordal, R.A.1    Nagy, A.2    Pintilie, M.3    Wong, C.S.4
  • 14
    • 34447502437 scopus 로고    scopus 로고
    • Upregulation of vascular endothelial growth factor receptors Flt-1 and Flk-1 following acute spinal cord contusion in rats
    • Choi J.S., Kim H.Y., Cha J.H., et al. Upregulation of vascular endothelial growth factor receptors Flt-1 and Flk-1 following acute spinal cord contusion in rats. J Histochem Cytochem 2007, 55:821-830.
    • (2007) J Histochem Cytochem , vol.55 , pp. 821-830
    • Choi, J.S.1    Kim, H.Y.2    Cha, J.H.3
  • 15
    • 17844378527 scopus 로고    scopus 로고
    • Pathophysiology of blood-spinal cord barrier in traumatic injury and repair
    • Sharma H.S. Pathophysiology of blood-spinal cord barrier in traumatic injury and repair. Curr Pharm Des 2005, 11:1353-1389.
    • (2005) Curr Pharm Des , vol.11 , pp. 1353-1389
    • Sharma, H.S.1
  • 16
    • 30344477376 scopus 로고    scopus 로고
    • The experimental study of hypoxia-inducible factor-1 alpha and its target genes in spinal cord injury
    • Xiaowei H., Ninghui Z., Wei X., Yiping T., Linfeng X. The experimental study of hypoxia-inducible factor-1 alpha and its target genes in spinal cord injury. Spinal Cord 2006, 44:35-43.
    • (2006) Spinal Cord , vol.44 , pp. 35-43
    • Xiaowei, H.1    Ninghui, Z.2    Wei, X.3    Yiping, T.4    Linfeng, X.5
  • 17
    • 78649346412 scopus 로고    scopus 로고
    • Sustained expression of vascular endothelial growth factor and angiopoietin-1 improves blood-spinal cord barrier integrity and functional recovery after spinal cord injury
    • Herrera J.J., Sundberg L.M., Zentilin L., Giacca M., Narayana P.A. Sustained expression of vascular endothelial growth factor and angiopoietin-1 improves blood-spinal cord barrier integrity and functional recovery after spinal cord injury. J Neurotrauma 2010, 27(11):2067-2076.
    • (2010) J Neurotrauma , vol.27 , Issue.11 , pp. 2067-2076
    • Herrera, J.J.1    Sundberg, L.M.2    Zentilin, L.3    Giacca, M.4    Narayana, P.A.5
  • 18
    • 33747354090 scopus 로고    scopus 로고
    • Neuronal loss and expression of neurotrophic factors in a model of rat chronic compressive spinal cord injury
    • Kasahara K., Nakagawa T., Kubota T. Neuronal loss and expression of neurotrophic factors in a model of rat chronic compressive spinal cord injury. Spine (Phila Pa 1976) 2006, 31(18):2059-2066.
    • (2006) Spine (Phila Pa 1976) , vol.31 , Issue.18 , pp. 2059-2066
    • Kasahara, K.1    Nakagawa, T.2    Kubota, T.3
  • 19
    • 69249108768 scopus 로고    scopus 로고
    • Reduced vascular endothelial growth factor expression in contusive spinal cord injury
    • Herrera J.J., Nesic O., Narayana P.A. Reduced vascular endothelial growth factor expression in contusive spinal cord injury. J Neurotrauma 2009, 26(7):995-1003.
    • (2009) J Neurotrauma , vol.26 , Issue.7 , pp. 995-1003
    • Herrera, J.J.1    Nesic, O.2    Narayana, P.A.3
  • 20
    • 73049117998 scopus 로고    scopus 로고
    • An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury
    • Liu Y., Figley S., Spratt S.K., et al. An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury. Neurobiol Dis 2010, 37:384-393.
    • (2010) Neurobiol Dis , vol.37 , pp. 384-393
    • Liu, Y.1    Figley, S.2    Spratt, S.K.3
  • 21
    • 0027374859 scopus 로고
    • Experimental chronic compressive cervical myelopathy
    • al-Mefty O., Harkey H.L., Marawi I., et al. Experimental chronic compressive cervical myelopathy. J Neurosurg 1993, 79:550-561.
    • (1993) J Neurosurg , vol.79 , pp. 550-561
    • al-Mefty, O.1    Harkey, H.L.2    Marawi, I.3
  • 22
    • 2342667384 scopus 로고    scopus 로고
    • New roles for VEGF in nervous tissue - beyond blood vessels
    • Rosenstein J.M., Krum J.M. New roles for VEGF in nervous tissue - beyond blood vessels. Exp Neurol 2004, 187:246-253.
    • (2004) Exp Neurol , vol.187 , pp. 246-253
    • Rosenstein, J.M.1    Krum, J.M.2
  • 23
    • 77958160282 scopus 로고    scopus 로고
    • Repetitive intrathecal VEGF(165) treatment has limited therapeutic effects after spinal cord injury in the rat
    • van Neerven S., Joosten E.A., Brook G.A., et al. Repetitive intrathecal VEGF(165) treatment has limited therapeutic effects after spinal cord injury in the rat. J Neurotrauma 2010, 27:1781-1791.
    • (2010) J Neurotrauma , vol.27 , pp. 1781-1791
    • van Neerven, S.1    Joosten, E.A.2    Brook, G.A.3
  • 24
    • 0036790806 scopus 로고    scopus 로고
    • Vascular endothelial growth factor protects cultured rat hippocampal neurons against hypoxic injury via an antiexcitotoxic, caspase-independent mechanism
    • Svensson B., Peters M., Konig H.G., et al. Vascular endothelial growth factor protects cultured rat hippocampal neurons against hypoxic injury via an antiexcitotoxic, caspase-independent mechanism. J Cereb Blood Flow Metab 2002, 22:1170-1175.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1170-1175
    • Svensson, B.1    Peters, M.2    Konig, H.G.3
  • 25
    • 24944471398 scopus 로고    scopus 로고
    • VEGF protects brain against focal ischemia without increasing blood-brain permeability when administered intracerebroventricularly
    • Kaya D., Gursoy-Ozdemir Y., Yemisci M., Tuncer N., Aktan S., Dalkara T. VEGF protects brain against focal ischemia without increasing blood-brain permeability when administered intracerebroventricularly. J Cereb Blood Flow Metab 2005, 25:1111-1118.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 1111-1118
    • Kaya, D.1    Gursoy-Ozdemir, Y.2    Yemisci, M.3    Tuncer, N.4    Aktan, S.5    Dalkara, T.6
  • 26
    • 80051490622 scopus 로고    scopus 로고
    • VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels
    • Cariboni A., Davidson K., Dozio E., et al. VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels. Development 2011, 138(17):3723-3733.
    • (2011) Development , vol.138 , Issue.17 , pp. 3723-3733
    • Cariboni, A.1    Davidson, K.2    Dozio, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.