Somatosensory-evoked potentials as an indicator for the extent of ultrastructural damage of the spinal cord after chronic compressive injuries in a rat model

Clinical Neurophysiology

Volumn 122, Issue 7, 2011, Pages 1440-1447

  Hu, Yong ^a   Wen, Chun Yi ^a   Li, Ting Hung ^a   Cheung, Matthew Man Hin ^b   Wu, Ed Xue kui ^b   Luk, Keith Dip Kei ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Chronic compression; Magnetic resonance imaging (MRI); Micro computed tomography ( CT); Spinal cord; Ultrastructure

Indexed keywords

POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLOOD VESSEL; CENTRAL GRAY MATTER; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; EVOKED SOMATOSENSORY RESPONSE; FEMALE; FRACTIONAL ANISOTROPY; HISTOLOGY; IMPLANTATION; LATENT PERIOD; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; SPINAL CORD COMPRESSION; SPINAL CORD LESION; ULTRASTRUCTURE; VERTEBRAL CANAL;

EID: 79957597549     PISSN: 13882457     EISSN: 18728952     Source Type: Journal    
DOI: 10.1016/j.clinph.2010.12.051     Document Type: Article

References (34)

1. al-Mefty O., Harkey H.L., Marawi I., Haines D.E., Peeler D.F., Wilner H.I., Smith R.R., Holaday H.R., Haining J.L., Russell W.F., et al. Experimental chronic compressive cervical myelopathy. J Neurosurg 1993, 79:550-561.
2. Baba H., Maezawa Y., Imura S., Kawahara N., Nakahashi K., Tomita K. Quantitative analysis of the spinal cord motoneuron under chronic compression and experimental observation in the mouse. J Neurol 1996, 243:109-116.
3. Baptiste D.C., Fehlings M.G. Pathophysiology of cervical myelopathy. Spine J 2006, 6:190S-197S.
4. Baron E.M., Young W.F. Cervical spondylotic myelopathy: a brief review of its pathophysiology, clinical course, and diagnosis. Neurosurgery 2007, 60:56-67.
5. Bednarik J., Kadanka Z., Dusek L., Novotny O., Surelova D., Urbanek I., Prokes B. Presymptomatic spondylotic cervical cord compression. Spine (Phila Pa 1976) 2004, 29:2260-2269.
6. Bednarik J., Kadanka Z., Vohanka S., Stejskal L., Vlach O., Schroder R. The value of somatosensory- and motor-evoked potentials in predicting and monitoring the effect of therapy in spondylotic cervical myelopathy. Prospective randomized study. Spine (Phila Pa 1976) 1999, 24:1593-1598.
7. Bouchard J.A., Bohlman H.H., Biro C. Intraoperative improvements of somatosensory evoked potentials: correlation to clinical outcome in surgery for cervical spondylitic myelopathy. Spine (Phila Pa 1976) 1996, 21:589-594.
8. Bruce J.C., Oatway M.A., Weaver L.C. Chronic pain after clip-compression injury of the rat spinal cord. Exp Neurol 2002, 178:33-48.
9. Cheung M.M., Li D.T., Hui E.S., Fan S., Ding A.Y., Hu Y., Wu E.X. In vivo diffusion tensor imaging of chronic spinal cord compression in rat model. Conf Proc IEEE Eng Med Biol Soc 2009, 1:2715-2718.
10. Cheung W.Y., Arvinte D., Wong Y.W., Luk K.D., Cheung K.M. Neurological recovery after surgical decompression in patients with cervical spondylotic myelopathy - A prospective study. Int Orthop 2008, 32:273-278.
11. Cruccu G., Aminoff M.J., Curio G., Guerit J.M., Kakigi R., Mauguiere F., Rossini P.M., Treede R.D., Garcia-Larrea L. Recommendations for the clinical use of somatosensory-evoked potentials. Clin Neurophysiol 2008, 119:1705-1719.
12. DeBoy C.A., Zhang J., Dike S., Shats I., Jones M., Reich D.S., Mori S., Nguyen T., Rothstein B., Miller R.H., Griffin J.T., Kerr D.A., Calabresi P.A. High resolution diffusion tensor imaging of axonal damage in focal inflammatory and demyelinating lesions in rat spinal cord. Brain 2007, 130:2199-2210.
13. Hama A., Sagen J. Behavioral characterization and effect of clinical drugs in a rat model of pain following spinal cord compression. Brain Res 2007, 1185:117-128.
14. Harkey H.L., Al-Mefty O. The Pathophysiology of Chronic Compressive Cervical Myelopathy. Cervical Spondylosis and Similar Disorders 1998, World Scientific Publishing Co. Pvt. Ltd., Singapore, pp. 141-166. K. Ono (Ed.).
15. Hu Y., Ding Y., Ruan D., Wong Y.W., Cheung K.M., Luk K.D. Prognostic value of somatosensory-evoked potentials in the surgical management of cervical spondylotic myelopathy. Spine (Phila Pa 1976) 2008, 33:E305-E310.
16. Hu Y., Luk K.D., Lu W.W., Leong J.C. Application of time-frequency analysis to somatosensory evoked potential for intraoperative spinal cord monitoring. J Neurol Neurosurg Psychiatry 2003, 74:82-87.
17. Ichihara K., Taguchi T., Sakuramoto I., Kawano S., Kawai S. Mechanism of the spinal cord injury and the cervical spondylotic myelopathy: new approach based on the mechanical features of the spinal cord white and gray matter. J Neurosurg 2003, 99:278-285.
18. Iwamoto H., Kuwahara H., Matsuda H., Noriage A., Yamano Y. Production of chronic compression of the cauda equina in rats for use in studies of lumbar spinal canal stenosis. Spine (Phila Pa 1976) 1995, 20:2750-2757.
19. Izumida M. A chronic spinal cord compression model in a rat with a 354A tumor. Nippon Seikeigeka Gakkai Zasshi 1995, 69:977-991.
20. Kim D.H., Vaccaro A.R., Henderson F.C., Benzel E.C. Molecular biology of cervical myelopathy and spinal cord injury: role of oligodendrocyte apoptosis. Spine J 2003, 3:510-519.
21. Kim P., Haisa T., Kawamoto T., Kirino T., Wakai S. Delayed Myelopathy Induced by Chronic Compression in the Rat Spinal Cord. Ann Neurol 2004, 55:503-511.
22. Lo Y.L. The role of electrophysiology in the diagnosis and management of cervical spondylotic myelopathy. Ann Acad Med Singapore 2007, 36:886-893.
23. Lo Y.L. How has electrophysiology changed the management of cervical spondylotic myelopathy?. Eur J Neurol 2008, 15:781-786.
24. Mair W.G., Druckman R. The pathology of spinal cord lesions and their relation to the clinical features in protrusion of cervical intervertebral discs; a report of four cases. Brain 1953, 76:70-91.
25. Matsumoto M., Toyama Y., Ishikawa M., Chiba K., Suzuki N., Fujimura Y. Increased signal intensity of the spinal cord on magnetic resonance images in cervical compressive myelopathy. Does it predict the outcome of conservative treatment?. Spine (Phila Pa 1976) 2000, 25:677-682.
26. McCormick W.E., Steinmetz M.P., Benzel E.C. Cervical spondylotic myelopathy: make the difficult diagnosis, then refer for surgery. Cleve Clin J Med 2003, 70:899-904.
27. Morishita Y., Hida S., Naito M., Matsushima U. Evaluation of cervical spondylotic myelopathy using somatosensory-evoked potentials. Int Orthop 2005, 29:343-346.
28. Ogino H., Tada K., Okada K., Yonenobu K., Yamamoto T., Ono K., Namiki H. Canal diameter, anteroposterior compression ratio, and spondylotic myelopathy of the cervical spine. Spine (Phila Pa 1976) 1983, 8:1-15.
29. Rao R. Neck Pain, Cervical Radiculopathy, and Cervical Myelopathy: Pathophysiology, Natural History, and Clinical Evaluation. J Bone Joint Surg Am 2002, 84:1872-1881.
30. Robinson L.R., Micklesen P.J., Tirschwell D.L., Lew H.L. Predictive value of somatosensory evoked potentials for awakening from coma. Crit Care Med 2003, 31:960-967.
31. Seyal M., Mull B. Mechanisms of signal change during intraoperative somatosensory evoked potential monitoring of the spinal cord. J Clin Neurophysiol 2002, 19:409-415.
32. Yamaura I., Yone K., Nakahara S., Nagamine T., Baba H., Uchida K., Komiya S. Mechanism of destructive pathologic changes in the spinal cord under chronic mechanical compression. Spine (Phila Pa 1976) 2002, 27:21-26.
33. Yoshizawa H. Presidential address: pathomechanism of myelopathy and radiculopathy from the viewpoint of blood flow and cerebrospinal fluid flow including a short historical review. Spine (Phila Pa 1976) 2002, 27:1255-1263.
34. Zhang Z.G., Yang J.L., Chan S.C., Luk K.D., Hu Y. Time-frequency component analysis of somatosensory evoked potentials in rats. Biomed Eng Online 2009, 8:4.