Analysis of Δ12-fatty acid desaturase function revealed that two distinct pathways are active for the synthesis of PUFAs in T. aureum ATCC 34304

Journal of Lipid Research

Volumn 53, Issue 6, 2012, Pages 1210-1222

  Matsuda, Takanori ^a   Sakaguchi, Keishi ^a   Hamaguchi, Rie ^a   Kobayashi, Takumi ^a   Abe, Eriko ^a   Hama, Yoichiro ^b   Hayashi, Masahiro ^c   Honda, Daiske ^d   Okita, Yuji ^e   Sugimoto, Shinichi ^e   Okino, Nozomu ^a   Ito, Makoto ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b SAGA UNIVERSITY   (Japan)

^c UNIVERSITY OF MIYAZAKI   (Japan)

^d KONAN UNIVERSITY   (Japan)

^e NIPPON SUISAN KAISHA LTD   (Japan)

Author keywords

Desaturase elongase (standard) pathway; Homologous recombination; Polyketide synthase like (PUFA synthase) pathway; Polyunsaturated fatty acid; Targeted gene disruption

Indexed keywords

ACYL COENZYME A DESATURASE; DOCOSAHEXAENOIC ACID; LINOLEIC ACID; OLEIC ACID;

ARTICLE; CONTROLLED STUDY; DELTA 12 FATTY ACID DESATURASE GENE; FATTY ACID METABOLISM; FATTY ACID SYNTHESIS; GENE; GENE DISRUPTION; GENE EXPRESSION; GENE FUNCTION; GENE ISOLATION; GENETIC TRANSFORMATION; HOMOLOGOUS RECOMBINATION; LIPID COMPOSITION; LIPID STORAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; THRAUSTOCHYTRIUM; THRAUSTOCHYTRIUM AUREUM; WILD TYPE;

AMINO ACID SEQUENCE; CLONING, MOLECULAR; EVOLUTION, MOLECULAR; FATTY ACID DESATURASES; FATTY ACIDS, UNSATURATED; MOLECULAR SEQUENCE DATA; PHYLOGENY; SACCHAROMYCES CEREVISIAE; SEQUENCE DELETION; STRAMENOPILES; SUBSTRATE SPECIFICITY;

EID: 84861447355     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M024935     Document Type: Article

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