A bioanalytical strategy utilizing dried blood spot sampling and LC-MS/MS in discovery toxicology studies

Bioanalysis

Volumn 4, Issue 9, 2012, Pages 1057-1064

  Discenza, Lorell ^a   Obermeier, Mary T ^a   Westhouse, Richard ^a   Olah, Timothy V ^a   D'Arienzo, Celia J ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ANALYTIC METHOD; ANALYTICAL ERROR; AREA UNDER THE CURVE; CONTROLLED STUDY; CORRELATION ANALYSIS; DILUTION; DRIED BLOOD SPOT TESTING; FILTRATION ASSISTED PROTEIN PRECIPITATION; LIQUID CHROMATOGRAPHY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PERFORMANCE; PLASMA; PRECIPITATION; REVIEW; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; DRIED BLOOD SPOT TESTING; DRUG TOXICITY; MACACA FASCICULARIS; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS; PLASMA; QUALITY CONTROL; RATS;

EID: 84861365955     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.12.69     Document Type: Review

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