Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture

Biomaterials

Volumn 33, Issue 23, 2012, Pages 5732-5741

  Feinberg, Adam W ^a   Alford, Patrick W ^a   Jin, Hongwei ^a   Ripplinger, Crystal M ^a   Werdich, Andreas A ^a   Sheehy, Sean P ^a   Grosberg, Anna ^a   Parker, Kevin Kit ^a  

^a HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

Cardiac tissue engineering; Cardiomyocyte; Fibronectin; Micropatterning; Polydimethylsiloxane

Indexed keywords

CARDIAC MUSCLES; CARDIAC MYOCYTES; CARDIAC TISSUE ENGINEERING; CARDIAC TISSUES; CARDIOMYOCYTES; COLLAGEN FIBRILS; COMBINED IMAGES; CONTRACTILE FORCE; CYTOSKELETAL; EXTRACELLULAR SPACE; FIBRONECTIN; FORCE GENERATION; LAMINAR STRUCTURE; MICRO PATTERNING; MICROPATTERNED SURFACE; MUSCLE TISSUES; NEONATAL RAT; PARALLEL ARRAYS; PEAK FORCE; QUANTITATIVE ASSAY; STRUCTURAL ORGANIZATION; TISSUE ARCHITECTURE; UNIAXIAL ALIGNMENT; VASCULAR NETWORK; VENTRICULAR MYOCYTES;

ALIGNMENT; CELL CULTURE; MUSCLE; POLYDIMETHYLSILOXANE; RAT CONTROL; SILICONES; TISSUE ENGINEERING;

HEART;

CALCIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANISOTROPY; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; HEART ELECTROPHYSIOLOGY; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTRACELLULAR SPACE; MUSCLE STRENGTH; NEWBORN; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RAT; SARCOMERE; SYSTOLE; TISSUE ENGINEERING; TISSUE STRUCTURE;

ANIMALS; CALCIUM; CELLS, CULTURED; DIMETHYLPOLYSILOXANES; FIBRONECTINS; HEART; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; SARCOMERES; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

RATTUS;

EID: 84861340604     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.04.043     Document Type: Article

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