Scaffold topography alters intracellular calcium dynamics in cultured cardiomyocyte networks

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 287, Issue 3 56-3, 2004, Pages

  Yin, Lihong ^a   Bien, Harold ^a   Entcheva, Emilia ^a,b,c  

^a St Francis Hospital The Heart Center   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

Arrhythmogenesis; Cardiac tissue engineering; Frequency; Sarcoplasmic reticulum load

Indexed keywords

CALCIUM ION;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL CULTURE; CELL FUNCTION; CELL STIMULATION; CELL STRUCTURE; CONTROLLED STUDY; DIASTOLE; FLUORESCENCE; HEART ARRHYTHMIA; HEART FUNCTION; HEART MUSCLE CELL; MICROENVIRONMENT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM; TISSUE ENGINEERING;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL CLOCKS; CAFFEINE; CALCIUM; CALIBRATION; CELLS, CULTURED; CYTOLOGICAL TECHNIQUES; FLUORESCENT DYES; FURA-2; INTRACELLULAR MEMBRANES; MYOCYTES, CARDIAC; OSMOLAR CONCENTRATION; RATS; RATS, SPRAGUE-DAWLEY; SARCOPLASMIC RETICULUM;

EID: 4143129840     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01120.2003     Document Type: Article

References (35)

1. Akins RE. Can tissue engineering mend broken hearts? Circ Res 90: 120-122, 2002.
2. Arutunyan A, Swift LM, and Sarvazyan N. Initiation and propagation of ectopic waves: insights from an in vitro model of ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol 283: H741-H749, 2002.
3. Baartscheer A, Schumacher CA, Belterman CN, Coronel R, and Fiolet JW. SR calcium handling and calcium after-transients in a rabbit model of heart failure. Cardiovasc Res 58: 99-108, 2003.
4. Bers DM. SR Ca loading in cardiac muscle preparations based on rapid-cooling contractures. Am J Physiol Cell Physiol 256: C109-C120, 1989.
5. Bers DM. Excitation-Contraction Coupling and Cardiac Contractile Force. Dordrecht: Kluwer Academic, 1993.
6. Bien H, Yin L, and Entcheva E. Cardiac cell networks on elastic microgrooved scaffolds. IEEE Eng Med Biol Mag 22: 108-112, 2003.
7. 2+ homeostasis influences the frequency-dependent force-generation in man. Basic Res Cardiol 94: 152-158, 1999.
8. Bursac N, Parker KK, Iravanian S, and Tung L. Cardiomyocyte cultures with controlled macroscopic anisotropy: a model for functional electrophysiological studies of cardiac muscle. Circ Res 91: E45-E54, 2002.
9. Cheung JY, Tillotson DL, Yelamarty RV, and Scaduto RC Jr. Cytosolic free calcium concentration in individual cardiac myocytes in primary culture. Am J Physiol Cell Physiol 256: C1120-C1130, 1989.
10. Chou L, Firth JD, Uitto VJ, and Brunette DM. Effects of titanium substratum and grooved surface topography on metalloproteinase-2 expression in human fibroblasts. J Biomed Mater Res 39: 437-445, 1998.
11. Clusin WT. Calcium and cardiac arrhythmias: DADs, EADs, and alternans. Crit Rev Clin Lab Sci 40: 337-375, 2003.
12. Curtis A and Wilkinson C. Topographical control of cells. Biomaterials 18: 1573-1583, 1997.
13. DeSantiago J, Maier LS, and Bers DM. Frequency-dependent acceleration of relaxation in the heart depends on CaMKII, but not phospholamban. J Mol Cell Cardiol 34: 975-984, 2002.
14. Deutsch J, Motlagh D, Russell B, and Desai TA. Fabrication of micro-textured membranes for cardiac myocyte attachment and orientation. J Biomed Mater Res 53: 267-275, 2000.
15. Entcheva E and Bien H. Tension development and nuclear eccentricity in topographically controlled cardiac syncytium. J Biomed Microdev 5: 163-168, 2003.
16. i changes in cardiac tissue constructs on 3D elastic matrices (Abstract). PACE Pacing Clin Electrophysiol 26: 1107, 2003.
17. Fast V and Kleber A. Anisotropic conduction in monolayers of neonatal rat heart cells cultured on collagen substrate. Circ Res 75: 591-595, 1994.
18. 2+] during inotropic interventions in isolated rat myocytes. J Physiol 437: 351-375, 1991.
19. Garfinkel A, Kim YH, Voroshilovsky O, Qu Z, Kil JR, Lee MH, Karagueuzian HS, Weiss JN, and Chen PS. Preventing ventricular fibrillation by flattening cardiac restitution. Proc Natl Acad Sci USA 97: 6061-6066, 2000.
20. Geiger B. Cell biology. Encounters in space. Science 294: 1661-1663, 2001.
21. Gilmour RF Jr. A novel approach to identifying antiarrhythmic drug targets. Drug Discov Today 8: 162-167, 2003.
22. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985.
23. Hein S, Elsasser A, Kostin S, Zimmermann R, and Schaper J. Functional disturbances due to structural remodeling in the failing human heart. Arch Mal Coeur Vaiss 95: 815-820, 2002.
24. Hoffman BF and Kelly JJ. Effects of rate and rhythm on contraction of rat papillary muscle. Am J Physiol 197: 1199-1204, 1959.
25. Howarth FC, Boyett MR, and White E. Rapid effects of cytochalasin-D on contraction and intracellular calcium in single rat ventricular myocytes. Pflügers Arch 436: 804-806, 1998.
26. 2+]-frequency relationships in rat ventricular trabeculae at physiological frequency. Am J Physiol Heart Circ Physiol 276: H9-H18, 1999.
27. 2+, is it really that simple? J Mol Cell Cardiol 35: 891-893, 2003.
28. McDevitt TC, Angello JC, Whitney ML, Reinecke H, Hauschka SD, Murry CE, and Stayton PS. In vitro generation of differentiated cardiac myofibers on micropatterned laminin surfaces. J Biomed Mater Res 60: 472-479, 2002.
29. Nave BT, Becker M, Roenicke V, and Henkel T. Validation of targets and drug candidates in an engineered three-dimensional cardiac tissue model. Drug Discov Today 7: 419-425, 2002.
30. Oakley C and Brunette DM. Topographic compensation: guidance and directed locomotion of fibroblasts on grooved micromachined substrata in the absence of microtubules. Cell Motil Cytoskeleton 31: 45-58, 1995.
31. Olbrich HG, Donck LV, Geerts H, Mutschler E, Kober G, and Kaltenbach M. Cyclosporine increases the intracellular free calcium concentration in electrically paced isolated rat cardiomyocytes. J Heart Lung Transplant 12: 652-658, 1993.
32. Pogwizd SM. Nonreentrant mechanisms underlying spontaneous ventricular arrhythmias in a model of nonischemic heart failure in rabbits. Circulation 92: 1034-1048, 1995.
33. Swynghedauw B. Molecular mechanisms of myocardial remodeling. Physiol Rev 79: 215-262, 1999.
34. 2+ mobilization during excitation-contraction in cultured cardiac myocytes exposed to antimony. Toxicol Appl Pharmacol 146: 104-115, 1997.
35. Walsh KB and Parks GE. Changes in cardiac myocyte morphology alter the properties of voltage-gated ion channels. Cardiovasc Res 55: 64-75, 2002.