Heparin modulates the conformation and signaling of platelet integrin αiIbβ3

Thrombosis Research

Volumn 129, Issue 6, 2012, Pages 743-749

  Yagi, Mayumi ^a   Murray, Jacqueline ^a,b   Strand, Kurt ^a   Blystone, Scott ^c   Interlandi, Gianluca ^d   Suda, Yasuo ^e   Sobel, Michael ^a,b  

^a VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c State University of New York Upstate Medical University: College of Medicine   (United States)

^d University of Washington   (United States)

^e KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Heparin; Integrin IIb 3 (platelet glycoprotein IIbIIIa); Platelet activation; Src kinase; Surface plasmon resonance; Tyrosine phosphorylation

Indexed keywords

AMINO ACID; BETA3 INTEGRIN; HEPARIN; INTEGRIN; PROTEIN ALPHA2BETA3 INTEGRIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; FLOW CYTOMETRY; HUMAN; HUMAN EXPERIMENT; LIGAND BINDING; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

AMINO ACID SEQUENCE; BLOOD PLATELETS; FLOW CYTOMETRY; HEPARIN; HUMANS; K562 CELLS; MOLECULAR SEQUENCE DATA; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 84861329394     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.11.054     Document Type: Article

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