Amino Acid Residues in the αIIb Subunit that Are Critical for Ligand Binding to Integrin αIIbβ3 Are Clustered in the β-Propeller Model

Journal of Biological Chemistry

Volumn 276, Issue 47, 2001, Pages 44275-44283

  Kamata, Tetsuji ^b,c   Tieu, Kenneth K ^d   Irie, Atsushi ^d   Springer, Timothy A ^a   Takada, Yoshikazu ^c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBODIES; BINDING ENERGY; MUTAGENESIS; SCANNING;

LIGAND BINDING;

BIOCHEMISTRY;

ALANINE; ALPHA2B BETA3 INTEGRIN; AMINO ACID; BETA3 INTEGRIN; CALCIUM; FIBRINOGEN; INTEGRIN; LIGAND; UNCLASSIFIED DRUG; FIBRINOGEN RECEPTOR;

ARTICLE; CALCIUM BINDING; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR MODEL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL; GENETICS; HAMSTER; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; CHO CELLS; CRICETINAE; FIBRINOGEN; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0035941265     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M107021200     Document Type: Article

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