Synthesis and biological activity of a model disaccharide containing a key unit in heparin for binding to platelets

Tetrahedron Letters

Volumn 37, Issue 7, 1996, Pages 1053-1056

  Suda, Yasuo ^a   Bird, Karyn ^b   Shiyama, Takaaki ^a   Koshida, Shuhei ^a   Marques, Dalila ^b   Fukase, Koichi ^a   Sobel, Michael ^b   Kusumoto, Shoichi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISACCHARIDE; HEPARIN;

ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG SYNTHESIS; HEPARIN BINDING; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION; THROMBOCYTE;

EID: 0030040812     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(95)02346-1     Document Type: Article

References (13)

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10. Activation of thioglycosides with N-bromosuccinimide and strong acid salts was reported (Fukase, K.; Hasuoka, A.; Kinoshita, I.; Aoki, Y.; Kusumoto, S. Tetrahedron, 1995, 51, 4923-4932). The combination of N-bromosuccinimide (NBS) and silver perchlorate in ether was effective for α-selective glycosidation with 6-O-Troc thioglycosides (Fukase, K; Kinoshita, I.; Kanoh, T.; Hasuoka, A.; Aoki, Y.; Shiyama, T.; Koshida, S.; Suda, Y.; Kusumoto, S. Abstracts of XVIIth Japan Carbohydrate Symposium, Kyoto, July 1995, No. C-9).
11. Activation of thioglycosides with N-bromosuccinimide and strong acid salts was reported (Fukase, K.; Hasuoka, A.; Kinoshita, I.; Aoki, Y.; Kusumoto, S. Tetrahedron, 1995, 51, 4923-4932). The combination of N-bromosuccinimide (NBS) and silver perchlorate in ether was effective for α-selective glycosidation with 6-O-Troc thioglycosides (Fukase, K; Kinoshita, I.; Kanoh, T.; Hasuoka, A.; Aoki, Y.; Shiyama, T.; Koshida, S.; Suda, Y.; Kusumoto, S. Abstracts of XVIIth Japan Carbohydrate Symposium, Kyoto, July 1995, No. C-9).
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