Investigating the biocompatibility of two new heavy intraocular dyes for vitreoretinal surgery with an isolated perfused vertebrate retina organ culture model and a retinal ganglion cell line

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 250, Issue 4, 2012, Pages 533-545

  Januschowski, Kai ^a   Mueller, Sebastian ^a   Spitzer, Martin S ^a   Hoffmann, Johanna ^a   Schramm, Charlotte ^a   Schultheiß, Maximilian ^a   Bartz Schmidt, Karl Ulrich ^a   Szurman, Peter ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Electroretinogram. Intraocular toxicity; Retinal toxicity; Vitreoretinal dyes

Indexed keywords

BRILLIANT BLUE; DYE; INDOCYANINE GREEN; TETRAZOLIUM; TRITON X 100; TRYPAN BLUE; BIOMATERIAL; COLORING AGENT; COOMASSIE BRILLIANT BLUE; FUCHSINE;

A WAVE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B WAVE; BIOCOMPATIBILITY; BOWMAN MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; COW; CYTOTOXICITY; ELECTROPHYSIOLOGY; ELECTRORETINOGRAM; ENVIRONMENTAL PARAMETERS; ENVIRONMENTAL TEMPERATURE; EPIRETINAL MEMBRANE; IMMUNOHISTOCHEMISTRY; MONOLAYER CULTURE; NONHUMAN; ORGAN CULTURE; OSMOTIC PRESSURE; PH; PHOTOSTIMULATION; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; VITREORETINAL SURGERY; ANIMAL; CATTLE; CELL SURVIVAL; CULTURE TECHNIQUE; DRUG COMBINATION; DRUG EFFECT; ELECTRORETINOGRAPHY; MATERIALS TESTING; ORGAN CULTURE TECHNIQUE; PERFUSION; RETINA; STAINING; TIME;

ANIMALS; BIOCOMPATIBLE MATERIALS; CATTLE; CELL CULTURE TECHNIQUES; CELL SURVIVAL; COLORING AGENTS; DRUG COMBINATIONS; ELECTRORETINOGRAPHY; MATERIALS TESTING; ORGAN CULTURE TECHNIQUES; PERFUSION; RETINA; RETINAL GANGLION CELLS; ROSANILINE DYES; STAINING AND LABELING; TIME FACTORS; TRYPAN BLUE; VITREORETINAL SURGERY;

EID: 84861320629     PISSN: 0721832X     EISSN: 1435702X     Source Type: Journal    
DOI: 10.1007/s00417-011-1895-2     Document Type: Article

References (25)

1. Kelly NE, Wendel RT (1991) Vitreous surgery for idiopathic macular holes. Results of a pilot study. Arch Ophthalmol 109: 654-659
2. Park DW, Sipperley JO, Sneed SR, Dugel PU, Jacobson J (1999) Macular hole surgery with internal-limiting membrane peeling and intravitreous air. Ophthalmology 106:1392-1397
3. Cherrick SR, Stein SW, Leevy CM, Davidson CS (1960) Indocyanine green: observations on its physical properties, plasma decay, and hepatic extraction. J Clin Invest 39:592-600
4. Haritoglou C, Gandorfer A, Gass CA, Schaumberger M, Ulbiq MW, Kampik A (2002) Indocyanine green-assisted peeling of the internal limiting membrane in macular hole surgery affects visual outcome: a clinicopathologic correlation. Am J Ophthalmol 134: 836-841
5. Kanda S, Uemura A, Yamashita T, Kita H, Yamakiri K, Sakamoto T (2004) Visual field defects after intravitreous administration of indocyanine green in macular hole surgery. Arch Ophthalmol 122:1447-1451
6. Remy M, Thaler S, Schumann RG, May CA, Fiedorowicz M, Schuettauf F, Grueterich M, Priglinger SG, Nentwich MM, Kampik A, Haritoglou C (2008) An in vivo evaluation of Brilliant Blue G in animals and humans. Br J Ophthalmol 92:1142-1147
7. Brown JP, Dorsky A, Enderlin FE (1980) Synthesis of 14 Clabelled FD&C Blue No. 1 (Brilliant Blue FCF) and its intestinal absorption and metabolic fate in rats. Food Cosmet Toxicol 18:1-5
8. Januschowski K, Mueller S, Spitzer MS, Lueke M, Bartz-Schmidt KU, Szurman P (2011) The effects of the intraocular dye brilliant blue (BBG) mixed with varying concentrations of glucose on retinal function in an isolated perfused vertebrate retina. Graefes Arch Clin Exp Ophthalmol 249:483-489
9. Georgiadis N, Kardasopoulos A, Bufidis T (1999) The evaluation of corneal graft tissue by the use of trypan blue. Ophthalmologica 213:8-11
10. Melles GR, de Waard PW, Pameyer JH, Houdijn Beekhuis W (1999) Trypan blue capsule staining to visualize the capsulorhexis in cataract surgery. J Cataract Refract Surg 25:7-9
11. Feron EJ, Veckeneer M, Van Parys-Van Ginderdeuren R, Lommel A, Melles GR, Stalmans P (2002) Trypan blue staining of epiretinal membranes in proliferative vitreoretinopathy. Arch Ophthalmol 120:141-144
12. Sayama Y, Miyaji T, Taki I, Kawai K, Uemura F, Azuma S, Takashi S, Hachisuka T (1954) Effect of trypan blue injection on the incidence of liver carcinoma in rats fed p-dimethylaminoazobenzene. Gan 45: 386-388
13. Van Dooren BT, Beekhuis WH, Pels E (2004) Biocompatibility of trypan blue with human corneal cells. Arch Ophthalmol 122: 736-742
14. Kodjikian L, Richter T, Halberstadt M, Beby F, Flueckiger F, Boehnke M, Garweg JG (2005) Toxic effects of indocyanine green, infracyanine green, and trypan blue on the human retinal pigmented epithelium. Graefes Arch Clin Exp Ophthalmol 243: 917-925
15. Lueke C, Lueke M, Dietlein TS, Hueber A, Jordan J, Sickel W, Kirchof B (2005) Retinal tolerance to dyes. Br J Ophthalmol 89:1188-1191
16. Veckeneer M, Van Overdam K, Monzer J, Kobuch K, van Marle W, Spekreijse H (2001) Ocular toxicity study of trypan blue injected into the vitreous cavity of rabbit eyes. Graefes Arch Clin Exp Ophthalmol 239:698-704
17. Lesnik Oberstein SY, Mura M, Tan SH, de Smet MD (2007) Heavy trypan blue staining of epiretinal membranes: an alternative to infracyanine green. Br J Ophthalmol 91:955-957
18. Stalmans P, Feron EJ, Parys-Van Ginderdeuren R, Van Lommel A, Melles GR, Veckeneer M(2003) Double vital staining using trypan blue and infracyanine green in macular pucker surgery. Br J Ophthalmol 87:713-716
19. Sheftel VO (2000) Polyethylene glycols (PEGs). In: Sheftel VO (ed) Indirect food additives and polymers: migration and toxicology. CRC Press, Boca Raton, pp 1114-1116
20. Boyland E, Charles RT, Gowing NC (1961) The induction of tumors in mice by intravaginal application of chemical compounds. Br JCancer 15:252
21. Henrich PB, Haritoglou C, Meyer P, Ferreira PR, Schoetzau A, Katamay A, Josifova J, Schneider U, Flammer J, Priglinger S (2010) Anatomical and functional outcome in brilliant blue G assisted chromovitrectomy. Acta Ophthalmol 88:588-593
22. Lueke M, Weiergräber M, Brand C, Siapich SA, Banat M, Hescheler J, Lueke C, Schneider T (2005) The isolated perfused bovine retina -a sensitive tool for pharmacological research on retinal function. Brain Res Brain Res Protoc 16: 27-36
23. Yuen D, Gonder J, Proulx A, Liu H, Hutnik C (2009) Comparison of the in vitro safety of intraocular dyes using two retinal cell lines: a focus on brilliant blue G and indocyanine green. Am J Ophthalmol 147:251-259
24. Lueke M, Januschowski K, Beutel J, Lueke C, Grisanti S, Peters S, Jaissle GB, Bartz-Schmidt KU, Szurman P (2008) Electrophysiological effects of Brilliant Blue G in the model of the isolated perfused vertebrate retina. Graefes Arch Clin Exp Ophthalmol 246:817-822
25. Borgens RB, Shi R (2000) Immediate recovery from spinal cord injury through molecular repair of nerve membranes with polyethylene glycol. FASEB J 14:27-35