메뉴 건너뛰기




Volumn 33, Issue 4, 2012, Pages 660-665

Dexamethasone levels and base-to-apex concentration gradients in the scala tympani perilymph after intracochlear delivery in the guinea pig

Author keywords

Cochlea; Drug delivery; Glucocorticoids; Intratympanic; Pharmacokinetics; Round window membrane; Steroids

Indexed keywords

DEXAMETHASONE;

EID: 84861309133     PISSN: 15317129     EISSN: 15374505     Source Type: Journal    
DOI: 10.1097/MAO.0b013e318254501b     Document Type: Article
Times cited : (53)

References (34)
  • 1
    • 73349126109 scopus 로고    scopus 로고
    • Intratympanic steroids for inner ear disorders: A review
    • Hu A, Parnes LS. Intratympanic steroids for inner ear disorders: a review. Audiol Neurootol 2009;14:373-82.
    • (2009) Audiol Neurootol , vol.14 , pp. 373-82
    • Hu, A.1    Parnes, L.S.2
  • 2
    • 73349112869 scopus 로고    scopus 로고
    • Principles of local drug delivery to the inner ear
    • Salt AN, Plontke SK. Principles of local drug delivery to the inner ear. Audiol Neurootol 2009;14:350-60.
    • (2009) Audiol Neurootol , vol.14 , pp. 350-360
    • Salt, A.N.1    Plontke, S.K.2
  • 3
    • 36549014716 scopus 로고    scopus 로고
    • Intratympanic versus intravenous delivery of methylprednisolone to cochlear perilymph
    • Bird PA, Begg EJ, Zhang M, et al. Intratympanic versus intravenous delivery of methylprednisolone to cochlear perilymph. Otol Neurotol 2007;28:1124-30.
    • (2007) Otol Neurotol , vol.28 , pp. 1124-30
    • Bird, P.A.1    Begg, E.J.2    Zhang, M.3
  • 4
    • 80051736576 scopus 로고    scopus 로고
    • Intratympanic versus intravenous delivery of dexamethasone and dexamethasone sodium phosphate to cochlear perilymph
    • Bird PA, Murray DP, Zhang M, et al. Intratympanic versus intravenous delivery of dexamethasone and dexamethasone sodium phosphate to cochlear perilymph. Otol Neurotol 2011;32:933-6.
    • (2011) Otol Neurotol , vol.32 , pp. 933-6
    • Bird, P.A.1    Murray, D.P.2    Zhang, M.3
  • 5
    • 0032974309 scopus 로고    scopus 로고
    • Corticosteroid pharmacokinetics in the inner ear fluids: An animal study followed by clinical application
    • Parnes LS, Sun AH, Freeman DJ. Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application. Laryngoscope 1999;109:1-17.
    • (1999) Laryngoscope , vol.109 , pp. 1-17
    • Parnes, L.S.1    Sun, A.H.2    Freeman, D.J.3
  • 6
    • 0034947151 scopus 로고    scopus 로고
    • Permeability of the round window membrane for prednisolone-21-hydrogen succinate. Prednisolone content of the perilymph after local administration vs. Systemic injection]
    • Bachmann G, Su J, Zumegen C et al. [Permeability of the round window membrane for prednisolone-21-hydrogen succinate. Prednisolone content of the perilymph after local administration vs. systemic injection]. HNO 2001;49:538-42.
    • (2001) HNO , vol.49 , pp. 538-42
    • Bachmann, G.1    Su, J.2    Zumegen, C.3
  • 7
    • 77951612982 scopus 로고    scopus 로고
    • Hyaluronic acid hydrogel sustains the delivery of dexamethasone across the round window membrane
    • Borden RC, Saunders JE, Berryhill WE, et al. Hyaluronic acid hydrogel sustains the delivery of dexamethasone across the round window membrane. Audiol Neurootol 2011;16:1-11.
    • (2011) Audiol Neurootol , vol.16 , pp. 1-11
    • Borden, R.C.1    Saunders, J.E.2    Berryhill, W.E.3
  • 8
    • 0034085181 scopus 로고    scopus 로고
    • Dexamethasone pharmacokinetics in the inner ear: Comparison of route of administration and use of facilitating agents
    • Chandrasekhar SS, Rubinstein RY, Kwartler JA, et al. Dexamethasone pharmacokinetics in the inner ear: comparison of route of administration and use of facilitating agents. Otolaryngol Head Neck Surg 2000;122:521-8.
    • (2000) Otolaryngol Head Neck Surg , vol.122 , pp. 521-8
    • Chandrasekhar, S.S.1    Rubinstein, R.Y.2    Kwartler, J.A.3
  • 9
    • 32844475191 scopus 로고    scopus 로고
    • Cochlear microdialysis for quantification of dexamethasone and fluorescein entry into scala tympani during round window administration
    • Hahn H, Kammerer B, DiMauro A, et al. Cochlear microdialysis for quantification of dexamethasone and fluorescein entry into scala tympani during round window administration. Hear Res 2006;212:236-44.
    • (2006) Hear Res , vol.212 , pp. 236-44
    • Hahn, H.1    Kammerer, B.2    DiMauro, A.3
  • 10
    • 41349085428 scopus 로고    scopus 로고
    • Dexamethasone concentration gradients along scala tympani after application to the round window membrane
    • Plontke SK, Biegner T, Kammerer B, et al. Dexamethasone concentration gradients along scala tympani after application to the round window membrane. Otol Neurotol 2008;29:401-6.
    • (2008) Otol Neurotol , vol.29 , pp. 401-6
    • Plontke, S.K.1    Biegner, T.2    Kammerer, B.3
  • 11
    • 0037972273 scopus 로고    scopus 로고
    • Distribution of gentamicin in the guinea pig inner ear after local or systemic application
    • Imamura S, Adams JC. Distribution of gentamicin in the guinea pig inner ear after local or systemic application. J Assoc Res Otolaryngol 2003;4:176-95.
    • (2003) J Assoc Res Otolaryngol , vol.4 , pp. 176-95
    • Imamura, S.1    Adams, J.C.2
  • 12
    • 33744471135 scopus 로고    scopus 로고
    • Demonstration of a longitudinal concentration gradient along scala tympani by sequential sampling of perilymph from the cochlear apex
    • Mynatt R, Hale SA, Gill RM, et al. Demonstration of a longitudinal concentration gradient along scala tympani by sequential sampling of perilymph from the cochlear apex. J Assoc Res Otolaryngol 2006;7:182-93.
    • (2006) J Assoc Res Otolaryngol , vol.7 , pp. 182-93
    • Mynatt, R.1    Hale, S.A.2    Gill, R.M.3
  • 13
    • 34347364786 scopus 로고    scopus 로고
    • Concentration gradient along the scala tympani after local application of gentamicin to the round window membrane
    • Plontke SK, Mynatt R, Gill RM et al. Concentration gradient along the scala tympani after local application of gentamicin to the round window membrane. Laryngoscope 2007;117:1191-8.
    • (2007) Laryngoscope , vol.117 , pp. 1191-8
    • Plontke, S.K.1    Mynatt, R.2    Gill, R.M.3
  • 14
    • 0021245059 scopus 로고
    • Distribution of hrp in the inner ear after injection into the middle ear cavity
    • Saijo S, Kimura RS. Distribution of HRP in the inner ear after injection into the middle ear cavity. Acta Otolaryngol 1984;97: 593-610.
    • (1984) Acta Otolaryngol , vol.97 , pp. 593-610
    • Saijo, S.1    Kimura, R.S.2
  • 15
    • 0345151830 scopus 로고    scopus 로고
    • Cochlear gene transfer: Round window versus cochleostomy inoculation
    • Stover T, Yagi M, Raphael Y. Cochlear gene transfer: round window versus cochleostomy inoculation. Hear Res 1999;136:124-30.
    • (1999) Hear Res , vol.136 , pp. 124-30
    • Stover, T.1    Yagi, M.2    Raphael, Y.3
  • 16
    • 34548476050 scopus 로고    scopus 로고
    • Marker retention in the cochlea following injections through the round window membrane
    • Salt AN, Sirjani DB, Hartsock JJ, et al. Marker retention in the cochlea following injections through the round window membrane. Hear Res 2007;232:78-86.
    • (2007) Hear Res , vol.232 , pp. 78-86
    • Salt, A.N.1    Sirjani, D.B.2    Hartsock, J.J.3
  • 17
    • 33646130839 scopus 로고    scopus 로고
    • Perilymph sampling from the cochlear apex: A reliable method to obtain higher purity perilymph samples from scala tympani
    • Salt AN, Hale SA, Plonkte SK. Perilymph sampling from the cochlear apex: a reliable method to obtain higher purity perilymph samples from scala tympani. J Neurosci Methods 2006;153:121-9.
    • (2006) J Neurosci Methods , vol.153 , pp. 121-9
    • Salt, A.N.1    Hale, S.A.2    Plonkte, S.K.3
  • 18
    • 0036835089 scopus 로고    scopus 로고
    • Analysis of gentamicin kinetics in fluids of the inner ear with round window administration
    • Plontke SK, Wood AW, Salt AN. Analysis of gentamicin kinetics in fluids of the inner ear with round window administration. Otol Neurotol 2002;23:967-74.
    • (2002) Otol Neurotol , vol.23 , pp. 967-74
    • Plontke, S.K.1    Wood, A.W.2    Salt, A.N.3
  • 19
    • 0042466677 scopus 로고    scopus 로고
    • Quantitative interpretation of corticosteroid pharmacokinetics in inner fluids using computer simulations
    • Plontke SK, Salt AN. Quantitative interpretation of corticosteroid pharmacokinetics in inner fluids using computer simulations. Hear Res 2003;182:34-42.
    • (2003) Hear Res , vol.182 , pp. 34-42
    • Plontke, S.K.1    Salt, A.N.2
  • 20
    • 77958469168 scopus 로고    scopus 로고
    • Pharmacokinetics of dexamethasone solution following intratympanic injection in guinea pig and sheep
    • Wang X, Fernandez R, Dellamary L, et al. Pharmacokinetics of dexamethasone solution following intratympanic injection in guinea pig and sheep. Audiol Neurootol 2011;16:233-41.
    • (2011) Audiol Neurootol , vol.16 , pp. 233-41
    • Wang, X.1    Fernandez, R.2    Dellamary, L.3
  • 21
  • 22
    • 0042967932 scopus 로고    scopus 로고
    • Contamination of perilymph sampled from the basal cochlear turn with cerebrospinal fluid
    • Salt AN, Kellner C, Hale S. Contamination of perilymph sampled from the basal cochlear turn with cerebrospinal fluid. Hear Res 2003;182:24-33.
    • (2003) Hear Res , Issue.182 , pp. 24-33
    • Salt, A.N.1    Kellner, C.2    Hale, S.3
  • 23
    • 11244309380 scopus 로고    scopus 로고
    • Novel slow-and fast-type drug release round-window microimplants for local drug application to the cochlea: An experimental study in guinea pigs
    • Arnold W, Senn P, Hennig M, et al. Novel slow-and fast-type drug release round-window microimplants for local drug application to the cochlea: an experimental study in guinea pigs. Audiol Neurootol 2005;10:53-63.
    • (2005) Audiol Neurootol , vol.10 , pp. 53-63
    • Arnold, W.1    Senn, P.2    Hennig, M.3
  • 24
    • 0027380817 scopus 로고
    • Osmotic pump implant for chronic infusion of drugs into the inner ear
    • Brown JN, Miller JM, Altschuler RA, et al. Osmotic pump implant for chronic infusion of drugs into the inner ear. Hear Res 1993;70: 167-72.
    • (1993) Hear Res , vol.70 , pp. 167-72
    • Brown, J.N.1    Miller, J.M.2    Altschuler, R.A.3
  • 25
    • 33644666957 scopus 로고    scopus 로고
    • Novel strategy for treatment of inner ears using a biodegradable gel
    • Endo T, Nakagawa T, Kita T, et al. Novel strategy for treatment of inner ears using a biodegradable gel. Laryngoscope 2005;115: 2016-20.
    • (2005) Laryngoscope , vol.115 , pp. 2016-20
    • Endo, T.1    Nakagawa, T.2    Kita, T.3
  • 26
    • 79958255457 scopus 로고    scopus 로고
    • Kinetics of reciprocating drug delivery to the inner ear
    • Pararas EE, Chen Z, Fiering J, et al. Kinetics of reciprocating drug delivery to the inner ear. J Control Release 2011;152:270-7.
    • (2011) J Control Release , vol.152 , pp. 270-277
    • Pararas, E.E.1    Chen, Z.2    Fiering, J.3
  • 27
    • 41849096031 scopus 로고    scopus 로고
    • A novel controlled local drug delivery system for inner ear disease
    • Paulson DP, Abuzeid W, Jiang H, et al. A novel controlled local drug delivery system for inner ear disease. Laryngoscope 2008;118: 706-11.
    • (2008) Laryngoscope , vol.118 , pp. 706-11
    • Paulson, D.P.1    Abuzeid, W.2    Jiang, H.3
  • 28
    • 78650735047 scopus 로고    scopus 로고
    • Oto-104: A sustained-release dexamethasone hydrogel for the treatment of otic disorders
    • Piu F, Wang X, Fernandez R, et al. OTO-104: a sustained-release dexamethasone hydrogel for the treatment of otic disorders. Otol Neurotol 2011;32:171-9.
    • (2011) Otol Neurotol , vol.32 , pp. 171-9
    • Piu, F.1    Wang, X.2    Fernandez, R.3
  • 29
    • 0035215123 scopus 로고    scopus 로고
    • A novel microperfusion system for the long-term local supply of drugs to the inner ear: Implantation and function in the rat model
    • Praetorius M, Limberger A, Muller M, et al. A novel microperfusion system for the long-term local supply of drugs to the inner ear: implantation and function in the rat model. Audiol Neurootol 2001;6:250-8.
    • (2001) Audiol Neurootol , vol.6 , pp. 250-258
    • Praetorius, M.1    Limberger, A.2    Muller, M.3
  • 30
    • 78650238229 scopus 로고    scopus 로고
    • Distribution of dexamethasone and preservation of inner ear function following intratympanic delivery of a gel-based formulation
    • Salt AN, Hartsock J, Plontke S, et al. Distribution of dexamethasone and preservation of inner ear function following intratympanic delivery of a gel-based formulation. Audiol Neurootol 2011;16:323-35.
    • (2011) Audiol Neurootol , vol.16 , pp. 323-35
    • Salt, A.N.1    Hartsock, J.2    Plontke, S.3
  • 31
    • 33644700581 scopus 로고    scopus 로고
    • Drug delivery to the cochlea using plga nanoparticles
    • Tamura T, Kita T, Nakagawa T, et al. Drug delivery to the cochlea using PLGA nanoparticles. Laryngoscope 2005;115:2000-5.
    • (2005) Laryngoscope , vol.115 , pp. 2000-2005
    • Tamura, T.1    Kita, T.2    Nakagawa, T.3
  • 32
    • 73349085573 scopus 로고    scopus 로고
    • Dose-dependent sustained release of dexamethasone in inner ear cochlear fluids using a novel local delivery approach
    • Wang X, Dellamary L, Fernandez R, et al. Dose-dependent sustained release of dexamethasone in inner ear cochlear fluids using a novel local delivery approach. Audiol Neurootol 2009;14:393-401.
    • (2009) Audiol Neurootol , vol.14 , pp. 393-401
    • Wang, X.1    Dellamary, L.2    Fernandez, R.3
  • 33
    • 0034912191 scopus 로고    scopus 로고
    • Targeted topical steroid therapy in sudden sensorineural hearing loss
    • Kopke RD, Hoffer ME, Wester D, et al. Targeted topical steroid therapy in sudden sensorineural hearing loss. Otol Neurotol 2001;22:475-9.
    • (2001) Otol Neurotol , vol.22 , pp. 475-9
    • Kopke, R.D.1    Hoffer, M.E.2    Wester, D.3
  • 34
    • 79251570548 scopus 로고    scopus 로고
    • Principles of inner ear sustained release following intratympanic administration
    • Wang X, Dellamary L, Fernandez R, et al. Principles of inner ear sustained release following intratympanic administration. Laryngoscope 2011;121:385-91.
    • (2011) Laryngoscope , vol.121 , pp. 385-91
    • Wang, X.1    Dellamary, L.2    Fernandez, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.