Concentration gradient along the scala tympani after local application of gentamicin to the round window membrane

Laryngoscope

Volumn 117, Issue 7, 2007, Pages 1191-1198

  Plontke, Stefan K ^a   Mynatt, Robert ^b   Gill, Ruth M ^c   Borgmann, Stefan ^d   Salt, Alec N ^c  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Cochlea; Drug delivery; Ototoxicity; Perilymph; Pharmacokinetics; Round window membrane

Indexed keywords

GENTAMICIN;

ANIMAL EXPERIMENT; ARTICLE; COCHLEA; COCHLEA FENESTRA; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG DETERMINATION; DRUG DISTRIBUTION; GUINEA PIG; HEARING LOSS; MEMBRANE PERMEABILITY; NONHUMAN; PERILYMPH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SAMPLING; VESTIBULAR FUNCTION;

ADMINISTRATION, TOPICAL; AMINOGLYCOSIDES; ANIMALS; BASILAR MEMBRANE; CELL MEMBRANE PERMEABILITY; GENTAMICINS; GUINEA PIGS; ROUND WINDOW; TIME FACTORS; TYMPANIC MEMBRANE;

EID: 34347364786     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MLG.0b013e318058a06b     Document Type: Article

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