Antimicrobial activity of licochalcone E against Staphylococcus aureus and its impact on the production of staphylococcal alpha-toxin

Journal of Microbiology and Biotechnology

Volumn 22, Issue 6, 2012, Pages 800-805

  Zhou, Tiezhong ^a   Deng, Xuming ^b   Qiu, Jiazhang ^b  

^a JINZHOU MEDICAL UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

Author keywords

Alphatoxin; Licochalcone E; Staphylococcus aureus

Indexed keywords

ANTIINFECTIVE AGENT; LICOCHALCONE E; STAPHYLOCOCCUS ALPHA TOXIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG POTENCY; DRUG STRUCTURE; HEMOLYSIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN SENSITIVE STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; BACTERIAL TOXINS; BLOTTING, WESTERN; CHALCONES; GENE EXPRESSION PROFILING; GLYCYRRHIZA; HEMOLYSIN PROTEINS; HEMOLYSIS; PLANT ROOTS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS;

GLYCYRRHIZA; STAPHYLOCOCCUS AUREUS;

EID: 84861307787     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1112.12020     Document Type: Article

References (28)

1. Baltina, L. A. 2003. Chemical modification of glycyrrhizic acid as a route to new bioactive compounds for medicine. Curr. Med. Chem. 10: 155-171.
2. Bhakdi, S. and J. Tranum-Jensen. 1991. Alpha-toxin of Staphylococcus aureus. Microbiol. Rev 55: 733-751.
3. Chan, P. F. and S. J. Foster. 1998. Role of SarA in virulence determinant production and environmental signal transduction in Staphylococcus aureus. J. Bacteriol. 180: 6232-6241.
4. Chang, H. J., G. Yoon, J. S. Park, M. H. Kim, M. K. Baek, N. H. Kim, et al. 2007. Induction of apoptosis by the licochalcone E in endothelial cells via modulation of NF-kappaB and Bcl-2 family. Biol. Pharm. Bull. 30: 2290-2293.
5. Fu, Y., T. C. Hsieh, J. Guo, J. Kunicki, M. Y. Lee, Z. Darzynkiewicz, and J. M. Wu. 2004. Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells. Biochem. Biophys. Res. Commun. 322: 263-270.
6. Gouaux, E. 1998. Alpha-hemolysin from Staphylococcus aureus: An archetype of beta-barrel, channel-forming toxins. J. Struct. Biol. 121: 110-122.
7. Grundmann, H., M. Aires-de-Sousa, J. Boyce, and E. Tiemersma. 2006. Emergence and resurgence of meticillin-resistant Staphylococcus aureus as a public-health threat. Lancet 368: 874-885.
8. Haraguchi, H., H. Ishikawa, K. Mizutani, Y. Tamura, and T. Kinoshita. 1998. Antioxidative and superoxide scavenging activities of retrochalcones in Glycyrrhiza inflata. Bioorg. Med. Chem. 6: 339-347.
9. Haraguchi, H., K. Tanimoto, Y. Tamura, K. Mizutani, and T. Kinoshita. 1998. Mode of antibacterial action of retrochalcones from Glycyrrhiza inflata. Phytochemistry 48: 125-129.
10. Hatano, T., Y. Shintani, Y. Aga, S. Shiota, T. Tsuchiya, and T. Yoshida. 2000. Phenolic constituents of licorice. VIII. Structures of glicophenone and glicoisoflavanone, and effects of licorice phenolics on methicillin-resistant Staphylococcus aureus. Chem. Pharm. Bull. (Tokyo) 48: 1286-1292.
11. Ingmer, H., A. Nielsen, K. F. Nielsen, D. Frees, and T. O. Larsen. 2010. Method for screening compounds that influence virulence gene expression in Staphylococcus aureus. Antimicrob. Agents Chemother 54: 509-512.
12. Koszczol, C., K. Bernardo, M. Kronke, and O. Krut. 2006. Subinhibitory quinupristin/dalfopristin attenuates virulence of Staphylococcus aureus. J. Antimicrob. Chemother 58: 564-574.
13. Kronke, M., K. Bernardo, N. Pakulat, S. Fleer, A. Schnaith, O. Utermohlen, O. Krut, and S. Muller. 2004. Subinhibitory concentrations of linezolid reduce Staphylococcus aureus virulence factor expression. Antimicrob. Agents Chemother. 48: 546-555.
14. Kuroda, M., H. Kuroda, L. Cui, and K. Hiramatsu. 2007. Subinhibitory concentrations of beta-lactam induce haemolytic activity in Staphylococcus aureus through the SaeRS two-component system. FEMS Microbiol. Lett. 268: 98-105.
15. Li, J. Z., Y. H. Mi, J. H. He, and X. M. Deng. 2010. A Short and efficient synthesis of licochalcone E. Synlett 15: 2289-2292.
16. Lowy, F. D. 1998. Staphylococcus aureus infections. N. Engl. J. Med. 339: 520-532.
17. Mi-Ichi, F., H. Miyadera, T. Kobayashi, S. Takamiya, S. Waki, S. Iwata, et al. 2005. Parasite mitochondria as a target of chemotherapy - Inhibitory effect of licochalcone A on the Plasmodium falciparum respiratory chain. Ann. NY Acad. Sci. 1056: 46-54.
18. Novick, R. P., S. Herbert, and P. Barry. 2001. Subinhibitory clindamycin differentially inhibits transcription of exoprotein genes in Staphylococcus aureus. Infect. Immun. 69: 2996-3003.
19. Sambanthamoorthy, K., M. S. Smeltzer, and M. O. Elasri. 2006. Identification and characterization of msa (SAI233), a gene involved in expression of SarA and several virulence factors in Staphylococcus aureus. Microbiology 152: 2559-2572.
20. Schlievert, P. M., M. M. Dinges, and P. M. Orwin. 2000. Exotoxins of Staphylococcus aureus. Clin. Microbiol. Rev. 13: 16-34.
21. Schneewind, O., J. B. Wardenburg, and R. J. Patel. 2007. Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia. Infect. Immun. 75: 1040-1044.
22. Shibata, S. 2000. A drug over the millennia: Pharmacognosy, chemistry, and pharmacology of licorice. Yakugaku Zasshi 120: 849-862.
23. Stevens, D. L., Y. S. Ma, D. B. Salmi, E. McIndoo, R. J. Wallace, and A. E. Bryant. 2007. Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillinsensitive and methicillin-resistant Staphylococcus aureus. J. Infect. Dis. 195: 202-211.
24. Tsukiyama, R., H. Katsura, N. Tokuriki, and M. Kobayashi. 2002. Antibacterial activity of licochalcone A against sporeforming bacteria. Antimicrob. Agents Chemother. 46: 1226-1230.
25. Woodford, N. 2005. Biological counterstrike: Antibiotic resistance mechanisms of Gram-positive cocci. Clin. Microbiol. Infect. 11 Suppl 3: 2-21.
26. Worlitzsch, D., H. Kaygin, A. Steinhuber, A. Dalhoff, K. Botzenhart, and G Doring. 2001. Effects of amoxicillin, gentamicin, and moxifloxacin on the hemolytic activity of Staphylococcus aureus in vitro and in vivo. Antimicrob. Agents Chemother. 45: 196-202
27. Yoon, G., Y. D. Jung, and S. H. Cheon. 2005. Cytotoxic allyl retrochalcone from the roots of Glycyrrhiza inflata. Chem. Pharm. Bull. (Tokyo) 53: 694-695.
28. Zhai, L., J. Blom, M. Chen, S. B. Christensen, and A. Kharazmi. 1995. The antileishmanial agent licochalcone A interferes with the function of parasite mitochondria. Antimicrob. Agents Chemother. 39: 2742-2748.