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Volumn 12, Issue 2, 2012, Pages 153-164

Syndromes predisposing to pediatric central nervous system tumors: Lessons learned and new promises

Author keywords

Brain tumor; Cancer predisposition; Central nervous system tumors; Child

Indexed keywords

BEVACIZUMAB; CYCLOPAMINE; ERLOTINIB; EVEROLIMUS; LAPATINIB; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; NEUROFIBROMIN; RAPAMYCIN; SONIC HEDGEHOG PROTEIN; TIPIFARNIB;

EID: 84861232260     PISSN: 15284042     EISSN: 15346293     Source Type: Journal    
DOI: 10.1007/s11910-011-0244-5     Document Type: Article
Times cited : (19)

References (95)
  • 1
    • 77951629484 scopus 로고    scopus 로고
    • TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors
    • Tabori U, Shlien A, Baskin B, et al. TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors. J Clin Oncol. 2010;28:1995-2001.
    • (2010) J Clin Oncol , vol.28 , pp. 1995-2001
    • Tabori, U.1    Shlien, A.2    Baskin, B.3
  • 2
    • 78649675614 scopus 로고    scopus 로고
    • Spectrum of SMARCB1/INI1 mutations in familial and sporadic rhabdoid tumors
    • Eaton KW, Tooke LS, Wainwright LM, et al. Spectrum of SMARCB1/INI1 mutations in familial and sporadic rhabdoid tumors. Pediatr Blood Canc. 2011;56:7-15.
    • (2011) Pediatr Blood Canc , vol.56 , pp. 7-15
    • Eaton, K.W.1    Tooke, L.S.2    Wainwright, L.M.3
  • 3
  • 4
    • 0024154605 scopus 로고
    • National Institutes of Health Consensus Development Conference Statement: neurofibromatosis. Bethesda, Md., USA, July 13-15, 1987
    • National Institutes of Health Consensus Development Conference Statement: neurofibromatosis. Bethesda, Md., USA, July 13-15, 1987. Neurofibromatosis 1988;1:172-8.
    • (1988) Neurofibromatosis , vol.1 , pp. 172-178
  • 5
    • 0025297599 scopus 로고
    • Type 1 neurofibromatosis gene: Identification of a large transcript disrupted in three NF1 patients
    • Wallace MR, Marchuk DA, Andersen LB, et al. Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients. Science. 1990;249:181-6.
    • (1990) Science , vol.249 , pp. 181-186
    • Wallace, M.R.1    Marchuk, D.A.2    Andersen, L.B.3
  • 6
    • 67649321430 scopus 로고    scopus 로고
    • Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis
    • McGillicuddy LT, Fromm JA, Hollstein PE, et al. Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis. Cancer Cell. 2009;16:44-54.
    • (2009) Cancer Cell , vol.16 , pp. 44-54
    • McGillicuddy, L.T.1    Fromm, J.A.2    Hollstein, P.E.3
  • 7
    • 80053154349 scopus 로고    scopus 로고
    • Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner
    • Banerjee S, Crouse NR, Emnett RJ, et al. Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner. Proc Natl Acad Sci USA. 2011.
    • (2011) Proc Natl Acad Sci USA
    • Banerjee, S.1    Crouse, N.R.2    Emnett, R.J.3
  • 9
    • 77955041914 scopus 로고    scopus 로고
    • Cyclic AMP suppression is sufficient to induce gliomagenesis in a mouse model of neurofibromatosis-1
    • Warrington NM, Gianino SM, Jackson E, et al. Cyclic AMP suppression is sufficient to induce gliomagenesis in a mouse model of neurofibromatosis-1. Cancer Res. 2010;70:5717-27.
    • (2010) Cancer Res , vol.70 , pp. 5717-5727
    • Warrington, N.M.1    Gianino, S.M.2    Jackson, E.3
  • 10
    • 0141529951 scopus 로고    scopus 로고
    • The neurofibromatosis 1 gene product neurofibromin regulates pituitary adenylate cyclase-activating polypeptide-mediated signaling in astrocytes
    • Dasgupta B, Dugan LL, Gutmann DH. The neurofibromatosis 1 gene product neurofibromin regulates pituitary adenylate cyclaseactivating polypeptide-mediated signaling in astrocytes. J Neurosci. 2003;23:8949-54. (Pubitemid 37210908)
    • (2003) Journal of Neuroscience , vol.23 , Issue.26 , pp. 8949-8954
    • Dasgupta, B.1    Dugan, L.L.2    Gutmann, D.H.3
  • 14
    • 0033836769 scopus 로고    scopus 로고
    • When do children with optic pathway tumours need treatment? An oncological perspective in 106 patients treated in a single centre
    • Grill J, Laithier V, Rodriguez D, et al. When do children with optic pathway tumours need treatment? An oncological perspective in 106 patients treated in a single centre. Eur J Pediatr. 2000;159:692-6. (Pubitemid 30658557)
    • (2000) European Journal of Pediatrics , vol.159 , Issue.9 , pp. 692-696
    • Grill, J.1    Laithier, V.2    Rodriguez, D.3    Raquin, M.-A.4    Pierre-Kahn, A.5    Kalifa, C.6
  • 15
    • 79958744743 scopus 로고    scopus 로고
    • Screening for symptomatic optic pathway glioma in children with neurofibromatosis type 1
    • author reply 818-819
    • Gutmann DH, Listernick R, Ferner RE. Screening for symptomatic optic pathway glioma in children with neurofibromatosis type 1. Eye (Lond). 2011;25:818. author reply 818-819.
    • (2011) Eye (Lond) , pp. 25818
    • Gutmann, D.H.1    Listernick, R.2    Ferner, R.E.3
  • 16
    • 34147172816 scopus 로고    scopus 로고
    • Optic pathway gliomas in neurofibromatosis-1: Controversies and recommendations
    • DOI 10.1002/ana.21107
    • Listernick R, Ferner RE, Liu GT, Gutmann DH. Optic pathway gliomas in neurofibromatosis-1: controversies and recommendations. Ann Neurol. 2007;61:189-98. (Pubitemid 46557343)
    • (2007) Annals of Neurology , vol.61 , Issue.3 , pp. 189-198
    • Listernick, R.1    Ferner, R.E.2    Liu, G.T.3    Gutmann, D.H.4
  • 17
    • 77951704065 scopus 로고    scopus 로고
    • Clinicopathologic study of glioblastoma in children with neurofibromatosis type 1
    • Huttner AJ, Kieran MW, Yao X, et al. Clinicopathologic study of glioblastoma in children with neurofibromatosis type 1. Pediatr Blood Canc. 2010;54:890-6.
    • (2010) Pediatr Blood Canc , vol.54 , pp. 890-896
    • Huttner, A.J.1    Kieran, M.W.2    Yao, X.3
  • 18
    • 77952091607 scopus 로고    scopus 로고
    • Neurofibromatosis type 1 and high-grade tumors of the central nervous system
    • Rosenfeld A, Listernick R, Charrow J, Goldman S. Neurofibromatosis type 1 and high-grade tumors of the central nervous system. Childs Nerv Syst. 2010;26:663-7.
    • (2010) Childs Nerv Syst , vol.26 , pp. 663-667
    • Rosenfeld, A.1    Listernick, R.2    Charrow, J.3    Goldman, S.4
  • 20
    • 0026043909 scopus 로고
    • The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma
    • Evans DG, Farndon PA, Burnell LD, et al. The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma. Br J Cancer. 1991;64:959-61.
    • (1991) Br J Cancer , vol.64 , pp. 959-961
    • Evans, D.G.1    Farndon, P.A.2    Burnell, L.D.3
  • 23
    • 0036648241 scopus 로고    scopus 로고
    • Mutations in SUFU predispose to medulloblastoma
    • Taylor MD, Liu L, Raffel C, et al. Mutations in SUFU predispose to medulloblastoma. Nat Genet. 2002;31:306-10.
    • (2002) Nat Genet , vol.31 , pp. 306-310
    • Taylor, M.D.1    Liu, L.2    Raffel, C.3
  • 25
    • 9644264182 scopus 로고    scopus 로고
    • Nevoid basal cell carcinoma (Gorlin) syndrome
    • DOI 10.1097/01.GIM.0000144188.15902.C4
    • Gorlin RJ. Nevoid basal cell carcinoma (Gorlin) syndrome. Genet Med. 2004;6:530-9. (Pubitemid 39576548)
    • (2004) Genetics in Medicine , vol.6 , Issue.6 , pp. 530-539
    • Gorlin, R.J.1
  • 26
    • 0037622972 scopus 로고    scopus 로고
    • Nevoid basal cell carcinoma syndrome: Relation with desmoplastic medulloblastoma in infancy: A population-based study and review of the literature
    • DOI 10.1002/cncr.11537
    • Amlashi SF, Riffaud L, Brassier G, Morandi X. Nevoid basal cell carcinoma syndrome: relation with desmoplastic medulloblastoma in infancy. A population-based study and review of the literature. Cancer. 2003;98:618-24. (Pubitemid 36886004)
    • (2003) Cancer , vol.98 , Issue.3 , pp. 618-624
    • Amlashi, S.F.A.1    Riffaud, L.2    Brassier, G.3    Morandi, X.4
  • 27
    • 75149189218 scopus 로고    scopus 로고
    • Neurooncology of familial cancer syndromes
    • Hottinger AF, Khakoo Y. Neurooncology of familial cancer syndromes. J Child Neurol. 2009;24:1526-35.
    • (2009) J Child Neurol , vol.24 , pp. 1526-1535
    • Hottinger, A.F.1    Khakoo, Y.2
  • 28
    • 33846406366 scopus 로고    scopus 로고
    • Radiation-induced brain tumours in nevoid basal cell carcinoma syndrome: Implications for treatment and surveillance
    • DOI 10.1007/s00381-006-0178-4
    • Choudry Q, Patel HC, Gurusinghe NT, Evans DG. Radiationinduced brain tumours in nevoid basal cell carcinoma syndrome: implications for treatment and surveillance. Childs Nerv Syst. 2007;23:133-6. (Pubitemid 46138500)
    • (2007) Child's Nervous System , vol.23 , Issue.1 , pp. 133-136
    • Choudry, Q.1    Patel, H.C.2    Gurusinghe, N.T.3    Evans, D.G.4
  • 30
    • 0034738979 scopus 로고    scopus 로고
    • Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
    • Taipale J, Chen JK, Cooper MK, et al. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature. 2000;406:1005-9.
    • (2000) Nature , vol.406 , pp. 1005-1009
    • Taipale, J.1    Chen, J.K.2    Cooper, M.K.3
  • 31
    • 77953693899 scopus 로고    scopus 로고
    • Targeting Hedgehog - A cancer stem cell pathway
    • Merchant AA, Matsui W. Targeting Hedgehog-a cancer stem cell pathway. Clin Cancer Res. 2010;16:3130-40.
    • (2010) Clin Cancer Res , vol.16 , pp. 3130-3140
    • Merchant, A.A.1    Matsui, W.2
  • 32
    • 70349244812 scopus 로고    scopus 로고
    • Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449
    • Rudin CM, Hann CL, Laterra J, et al. Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449. N Engl J Med. 2009;361:1173-8.
    • (2009) N Engl J Med , vol.361 , pp. 1173-1178
    • Rudin, C.M.1    Hann, C.L.2    Laterra, J.3
  • 33
    • 79955034739 scopus 로고    scopus 로고
    • Medulloblastoma comprises four distinct molecular variants
    • Northcott PA, Korshunov A,Witt H, et al.Medulloblastoma comprises four distinct molecular variants. J Clin Oncol. 2010;29:1408-14.
    • (2010) J Clin Oncol , vol.29 , pp. 1408-1414
    • Northcott, P.A.1    Korshunov, A.2    Witt, H.3
  • 35
    • 0032438210 scopus 로고    scopus 로고
    • Tuberous sclerosis complex consensus conference: Revised clinical diagnostic criteria
    • Roach ES, Gomez MR, Northrup H. Tuberous sclerosis complex consensus conference: revised clinical diagnostic criteria. J Child Neurol. 1998;13:624-8. (Pubitemid 29035481)
    • (1998) Journal of Child Neurology , vol.13 , Issue.12 , pp. 624-628
    • Roach, E.S.1    Gomez, M.R.2    Northrup, H.3
  • 41
    • 78049510428 scopus 로고    scopus 로고
    • Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis
    • Krueger DA, Care MM, Holland K, et al. Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis. N Engl J Med. 2010;363:1801-11.
    • (2010) N Engl J Med , vol.363 , pp. 1801-1811
    • Krueger, D.A.1    Care, M.M.2    Holland, K.3
  • 42
    • 79959262531 scopus 로고    scopus 로고
    • Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: A phase 2 trial
    • Davies DM, de Vries PJ, Johnson SR, et al. Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: a phase 2 trial. Clin Cancer Res. 2011;17:4071-81.
    • (2011) Clin Cancer Res , vol.17 , pp. 4071-4081
    • Davies, D.M.1    De Vries, P.J.2    Johnson, S.R.3
  • 43
    • 38049177875 scopus 로고    scopus 로고
    • Sirolimus therapy in tuberous sclerosis or sporadic lymphangioleiomyomatosis
    • Davies DM, Johnson SR, Tattersfield AE, et al. Sirolimus therapy in tuberous sclerosis or sporadic lymphangioleiomyomatosis. N Engl J Med. 2008;358:200-3.
    • (2008) N Engl J Med , vol.358 , pp. 200-203
    • Davies, D.M.1    Johnson, S.R.2    Tattersfield, A.E.3
  • 44
    • 0037268338 scopus 로고    scopus 로고
    • The fanconi anaemia/BRCA pathway
    • DOI 10.1038/nrc970
    • D'Andrea AD, Grompe M. The Fanconi anaemia/BRCA pathway. Nat Rev Cancer. 2003;3:23-34. (Pubitemid 37328884)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.1 , pp. 23-34
    • D'Andrea, A.D.1    Grompe, M.2
  • 46
    • 33846415079 scopus 로고    scopus 로고
    • Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2
    • DOI 10.1136/jmg.2006.043257
    • Alter BP, Rosenberg PS, Brody LC. Clinical and molecular features associated with biallelic mutations in FANCD1/BRCA2. J Med Genet. 2007;44:1-9. (Pubitemid 46142832)
    • (2007) Journal of Medical Genetics , vol.44 , Issue.1 , pp. 1-9
    • Alter, B.P.1    Rosenberg, P.S.2    Brody, L.C.3
  • 47
    • 67650403821 scopus 로고    scopus 로고
    • Genotype-phenotype correlations in Fanconi anemia
    • Neveling K, Endt D, Hoehn H, Schindler D. Genotype-phenotype correlations in Fanconi anemia. Mutat Res. 2009;668:73-91.
    • (2009) Mutat Res , vol.668 , pp. 73-91
    • Neveling, K.1    Endt, D.2    Hoehn, H.3    Schindler, D.4
  • 50
    • 70349320378 scopus 로고    scopus 로고
    • 2009 version of the chompret criteria for Li Fraumeni syndrome
    • author reply e110
    • Tinat J, Bougeard G, Baert-Desurmont S, et al. 2009 version of the Chompret criteria for Li Fraumeni syndrome. J Clin Oncol. 2009;27:e108-109. author reply e110.
    • (2009) J Clin Oncol. , vol.27
    • Tinat, J.1    Bougeard, G.2    Baert-Desurmont, S.3
  • 51
    • 77950497158 scopus 로고    scopus 로고
    • Universal poor survival in children with medulloblastoma harboring somatic TP53 mutations
    • Tabori U, Baskin B, Shago M, et al. Universal poor survival in children with medulloblastoma harboring somatic TP53 mutations. J Clin Oncol. 2010;28:1345-50.
    • (2010) J Clin Oncol , vol.28 , pp. 1345-1350
    • Tabori, U.1    Baskin, B.2    Shago, M.3
  • 53
    • 79957474904 scopus 로고    scopus 로고
    • Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: A prospective observational study
    • Villani A, Tabori U, Schiffman J, et al. Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study. Lancet Oncol. 2011;12:559-67.
    • (2011) Lancet Oncol , vol.12 , pp. 559-567
    • Villani, A.1    Tabori, U.2    Schiffman, J.3
  • 54
    • 78651120360 scopus 로고
    • Malignant tumors of the central nervous system associated with familial polyposis of the colon: Report of two cases
    • Turcot J, Despres JP. St Pierre F: Malignant tumors of the central nervous system associated with familial polyposis of the colon: report of two cases. Dis Colon Rectum. 1959;2:465-8.
    • (1959) Dis Colon Rectum , vol.2 , pp. 465-468
    • Turcot, J.1    Despres, J.P.2    St Pierre, F.3
  • 55
    • 0030798827 scopus 로고    scopus 로고
    • Brain tumor-polyposis syndrome: Two genetic diseases?
    • Paraf F, Jothy S, Van Meir EG. Brain tumor-polyposis syndrome: two genetic diseases? J Clin Oncol. 1997;15:2744-58. (Pubitemid 27289909)
    • (1997) Journal of Clinical Oncology , vol.15 , Issue.7 , pp. 2744-2758
    • Paraf, F.1    Jothy, S.2    Van Meir, E.G.3
  • 56
    • 50649111364 scopus 로고    scopus 로고
    • Constitutional mismatch repair-deficiency syndrome: Have we so far seen only the tip of an iceberg?
    • Wimmer K, Etzler J. Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg? Hum Genet. 2008;124:105-22.
    • (2008) Hum Genet , vol.124 , pp. 105-122
    • Wimmer, K.1    Etzler, J.2
  • 59
    • 78149280797 scopus 로고    scopus 로고
    • The gastrointestinal phenotype of germline biallelic mismatch repair gene mutations
    • Durno CA, Holter S, Sherman PM, Gallinger S. The gastrointestinal phenotype of germline biallelic mismatch repair gene mutations. Am J Gastroenterol. 2010;105:2449-56.
    • (2010) Am J Gastroenterol , vol.105 , pp. 2449-2456
    • Durno, C.A.1    Holter, S.2    Sherman, P.M.3    Gallinger, S.4
  • 61
    • 84861227969 scopus 로고    scopus 로고
    • Distinctive clinical genetic and cancer features of children with mismatch repair cancer susceptibility and RAS/MAPK syndromes [abstract 2010- A-294-ISPNO]
    • Presented at the. Vienna, Austria; June 20-23
    • Dumo C, Hawkins C, Aronson M, et al. Distinctive clinical, genetic and cancer features of children with mismatch repair cancer susceptibility and RAS/MAPK syndromes [abstract 2010- A-294-ISPNO]. Presented at the 14th International Symposium on Pediatric Neuro-oncology (ISPNO). Vienna, Austria; June 20-23, 2010.
    • (2010) 14th International Symposium on Pediatric Neuro-oncology (ISPNO)
    • Dumo, C.1    Hawkins, C.2    Aronson, M.3
  • 62
    • 37549059947 scopus 로고    scopus 로고
    • Hypothesis: Possible role of retinoic acid therapy in patients with biallelic mismatch repair gene defects
    • Gottschling S, Reinhard H, Pagenstecher C, et al. Hypothesis: Possible role of retinoic acid therapy in patients with biallelic mismatch repair gene defects. Eur J Pediatr. 2008;167:225-9.
    • (2008) Eur J Pediatr , vol.167 , pp. 225-229
    • Gottschling, S.1    Reinhard, H.2    Pagenstecher, C.3
  • 64
    • 0031672984 scopus 로고    scopus 로고
    • Pineoblastoma presenting in familial adenomatous polyposis (FAP): Random association, FAP variant or Turcot syndrome?
    • Ikeda J, Sawamura Y, van Meir EG. Pineoblastoma presenting in familial adenomatous polyposis (FAP): random association, FAP variant or Turcot syndrome? Br J Neurosurg. 1998;12:576-8. (Pubitemid 28566958)
    • (1998) British Journal of Neurosurgery , vol.12 , Issue.6 , pp. 576-578
    • Ikeda, J.1    Sawamura, Y.2    Van Meir, E.G.3
  • 65
    • 0028970197 scopus 로고
    • The molecular basis of Turcot's syndrome
    • Hamilton SR, Liu B, Parsons RE, et al. The molecular basis of Turcot's syndrome. N Engl J Med. 1995;332:839-47.
    • (1995) N Engl J Med , vol.332 , pp. 839-847
    • Hamilton, S.R.1    Liu, B.2    Parsons, R.E.3
  • 66
    • 75349102009 scopus 로고    scopus 로고
    • The adenomatous polyposis coli tumor suppressor and Wnt signaling in the regulation of apoptosis
    • Benchabane H, Ahmed Y. The adenomatous polyposis coli tumor suppressor and Wnt signaling in the regulation of apoptosis. Adv Exp Med Biol. 2009;656:75-84.
    • (2009) Adv Exp Med Biol , vol.656 , pp. 75-84
    • Benchabane, H.1    Ahmed, Y.2
  • 67
    • 33846896438 scopus 로고    scopus 로고
    • Brain tumors in individuals with Familial Adenomatous Polyposis: A cancer registry experience and pooled case report analysis
    • DOI 10.1002/cncr.22475
    • Attard TM, Giglio P, Koppula S, et al. Brain tumors in individuals with familial adenomatous polyposis: a cancer registry experience and pooled case report analysis. Cancer. 2007;109:761-6. (Pubitemid 46233238)
    • (2007) Cancer , vol.109 , Issue.4 , pp. 761-766
    • Attard, T.M.1    Giglio, P.2    Koppula, S.3    Snyder, C.4    Lynch, H.T.5
  • 71
    • 77951726598 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors
    • Wong HK, Lahdenranta J, Kamoun WS, et al. Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors. Cancer Res. 2010;70:3483-93.
    • (2010) Cancer Res , vol.70 , pp. 3483-3493
    • Wong, H.K.1    Lahdenranta, J.2    Kamoun, W.S.3
  • 72
    • 79959260091 scopus 로고    scopus 로고
    • Empirical development of improved diagnostic criteria for neurofibromatosis 2
    • Baser ME, Friedman JM, Joe H, et al. Empirical development of improved diagnostic criteria for neurofibromatosis 2. Genet Med. 2011;13:576-81.
    • (2011) Genet Med , vol.13 , pp. 576-581
    • Baser, M.E.1    Friedman, J.M.2    Joe, H.3
  • 75
    • 43449085188 scopus 로고    scopus 로고
    • Presymptomatic genetic testing in children for neurofibromatosis 2
    • Twomey JG, Bove C, Cassidy D. Presymptomatic genetic testing in children for neurofibromatosis 2. J Pediatr Nurs. 2008;23:183-94.
    • (2008) J Pediatr Nurs , vol.23 , pp. 183-194
    • Twomey, J.G.1    Bove, C.2    Cassidy, D.3
  • 76
    • 77956307565 scopus 로고    scopus 로고
    • Erlotinib for progressive vestibular schwannoma in neurofibromatosis 2 patients
    • Plotkin SR, Halpin C, McKenna MJ, et al. Erlotinib for progressive vestibular schwannoma in neurofibromatosis 2 patients. Otol Neurotol. 2010;31:1135-43.
    • (2010) Otol Neurotol , vol.31 , pp. 1135-1143
    • Plotkin, S.R.1    Halpin, C.2    McKenna, M.J.3
  • 77
    • 75749140889 scopus 로고    scopus 로고
    • Bevacizumab induces regression of vestibular schwannomas in patients with neurofibromatosis type 2
    • Mautner VF, Nguyen R, Kutta H, et al. Bevacizumab induces regression of vestibular schwannomas in patients with neurofibromatosis type 2. Neuro Oncol. 2010;12:14-8.
    • (2010) Neuro Oncol , vol.12 , pp. 14-18
    • Mautner, V.F.1    Nguyen, R.2    Kutta, H.3
  • 78
    • 67651173054 scopus 로고    scopus 로고
    • Hearing improvement after bevacizumab in patients with neurofibromatosis type 2
    • Plotkin SR, Stemmer-Rachamimov AO, Barker 2nd FG, et al. Hearing improvement after bevacizumab in patients with neurofibromatosis type 2. N Engl J Med. 2009;361:358-67.
    • (2009) N Engl J Med , vol.361 , pp. 358-367
    • Plotkin, S.R.1    Stemmer-Rachamimov, A.O.2    Barker, I.I.F.G.3
  • 81
    • 78649999605 scopus 로고    scopus 로고
    • Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway
    • Jagani Z, Mora-Blanco EL, Sansam CG, et al. Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway. Nat Med. 2010;16:1429-33.
    • (2010) Nat Med , vol.16 , pp. 1429-1433
    • Jagani, Z.1    Mora-Blanco, E.L.2    Sansam, C.G.3
  • 82
    • 58549119586 scopus 로고    scopus 로고
    • Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor
    • Chi SN, Zimmerman MA, Yao X, et al. Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor. J Clin Oncol. 2009;27:385-9.
    • (2009) J Clin Oncol , vol.27 , pp. 385-389
    • Chi, S.N.1    Zimmerman, M.A.2    Yao, X.3
  • 83
    • 77955865421 scopus 로고    scopus 로고
    • Atypical teratoid or rhabdoid tumors: Improved outcome with high-dose chemotherapy
    • Finkelstein-Shechter T, Gassas A, Mabbott D, et al. Atypical teratoid or rhabdoid tumors: improved outcome with high-dose chemotherapy. J Pediatr Hematol Oncol. 2010;32:e182-186.
    • (2010) J Pediatr Hematol Oncol , vol.32
    • Finkelstein-Shechter, T.1    Gassas, A.2    Mabbott, D.3
  • 84
    • 20144383987 scopus 로고    scopus 로고
    • Atypical teratoid/rhabdoid tumors (ATRT): Improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy
    • Tekautz TM, Fuller CE, Blaney S, et al. Atypical teratoid/rhabdoid tumors (ATRT): improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy. J Clin Oncol. 2005;23:1491-9.
    • (2005) J Clin Oncol , vol.23 , pp. 1491-1499
    • Tekautz, T.M.1    Fuller, C.E.2    Blaney, S.3
  • 88
    • 79956317112 scopus 로고    scopus 로고
    • Von Hippel-Lindau disease: A clinical and scientific review
    • Maher ER, Neumann HP, Richard S. von Hippel-Lindau disease: a clinical and scientific review. Eur J Hum Genet. 2011;19:617-23.
    • (2011) Eur J Hum Genet , vol.19 , pp. 617-623
    • Maher, E.R.1    Neumann, H.P.2    Richard, S.3
  • 90
    • 58849157647 scopus 로고    scopus 로고
    • Cowden syndrome: A critical review of the clinical literature
    • Pilarski R. Cowden syndrome: a critical review of the clinical literature. J Genet Couns. 2009;18:13-27.
    • (2009) J Genet Couns , vol.18 , pp. 13-27
    • Pilarski, R.1
  • 91
    • 70350238781 scopus 로고    scopus 로고
    • PTEN hamartoma tumor syndrome: An overview
    • Hobert JA, Eng C. PTEN hamartoma tumor syndrome: an overview. Genet Med. 2009;11:687-94.
    • (2009) Genet Med , vol.11 , pp. 687-694
    • Hobert, J.A.1    Eng, C.2
  • 92
  • 93
    • 33749678963 scopus 로고    scopus 로고
    • Ataxia-telangiectasia and related diseases
    • Frappart PO, McKinnon PJ. Ataxia-telangiectasia and related diseases. Neuromolecular Med. 2006;8:495-511.
    • (2006) Neuromolecular Med , vol.8 , pp. 495-511
    • Frappart, P.O.1    McKinnon, P.J.2
  • 94
    • 4444339751 scopus 로고    scopus 로고
    • ATM and ataxia telangiectasia
    • McKinnon PJ. ATM and ataxia telangiectasia. EMBO Rep. 2004;5:772-6.
    • (2004) EMBO Rep , vol.5 , pp. 772-776
    • McKinnon, P.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.