The relationship between shear rate and flow-mediated dilation is altered by acute exercise

Acta Physiologica

Volumn 205, Issue 3, 2012, Pages 394-402

  Llewellyn, T L ^a   Chaffin, M E ^a   Berg, K E ^a   Meendering, J R ^b  

^a UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^b SOUTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Flow mediated dilation; Nitric oxide; Running; Shear rate

Indexed keywords

ADULT; ARTERY ENDOTHELIUM; ARTICLE; BLOOD FLOW; BLOOD VESSEL DIAMETER; BLOOD VESSEL FUNCTION; BRACHIAL ARTERY; COMPARATIVE STUDY; EXERCISE; FEMALE; FLOW MEDIATED DILATION; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; REST; SHEAR FLOW; SHEAR RATE; VASODILATATION;

ADULT; BLOOD FLOW VELOCITY; BRACHIAL ARTERY; ENDOTHELIUM, VASCULAR; EXERCISE; FEMALE; HUMANS; MALE; NITROGLYCERIN; OXYGEN CONSUMPTION; REGIONAL BLOOD FLOW; REST; VASODILATION; VASODILATOR AGENTS;

EID: 84861229655     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2012.02417.x     Document Type: Article

References (31)

1. Atkinson, G., Batterham, A.M., Black, M.A., Cable, N.T., Hopkins, N.D., Dawson, E.A., Thijssen, D.H., Jones, H., Tinken, T.M. & Green, D.J. 2009. Is the ratio of flow-mediated dilation and shear rate a statistically sound approach to normalization in cross-sectional studies on endothelial function? J Appl Physiol 107, 1893-1899.
2. Borg, G.A. 1982. Psychophysical bases of perceived exertion. Med Sci Sports Exerc 14, 377-381.
3. Corretti, M.C., Anderson, T.J., Benjamin, E.J., Celermajer, D., Charbonneau, F., Creager, M.A., Deanfield, J., Drexler, H., Gerhard-Herman, M., Herrington, D., Vallance, P., Vita, J., Vogel, R. & International Brachial Artery Reactivity Task Force 2002. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 39, 257-265.
4. Cosio-Lima, L.M., Thompson, P.D., Reynolds, K.L., Headley, S.A., Winter, C.R., Manos, T., Lagasse, M.A., Todorovich, J.R. & Germain, M. 2006. The acute effect of aerobic exercise on brachial artery endothelial function in renal transplant recipients. Prev Cardiol 9, 211-214.
5. Dawson, E.A., Whyte, G.P., Black, M.A., Jones, H., Hopkins, N., Oxborough, D., Gaze, D., Shave, R.E., Wilson, M., George, K.P. & Green, D.J. 2008. Changes in vascular and cardiac function after prolonged strenuous exercise in humans. J Appl Physiol 105, 1562-1568.
6. Gielen, S., Schuler, G. & Adams, V. 2010. Cardiovascular effects of exercise training: molecular mechanisms. Circulation 122, 1221-1238.
7. Goto, C., Higashi, Y., Kimura, M., Noma, K., Hara, K., Nakagawa, K., Kawamura, M., Chayama, K., Yoshizumi, M. & Nara, I. 2003. Effect of different intensities of exercise on endothelium-dependent vasodilation in humans: role of endothelium-dependent nitric oxide and oxidative stress. Circulation 108, 530-535.
8. Green, D.J., Maiorana, A., O'Driscoll, G. & Taylor, R. 2004. Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol 561, 1-25.
9. Green, D.J., Naylor, L.H. & George, K. 2006. Cardiac and vascular adaptations to exercise. Curr Opin Clin Nutr Metab Care 9, 677-684.
10. Green, D.J., O'Driscoll, G., Joyner, M.J. & Cable, N.T. 2008. Exercise and cardiovascular risk reduction: time to update the rationale for exercise? J Appl Physiol 105, 766-768.
11. Hambrecht, R., Adams, V., Erbs, S., Linke, A., Krankel, N., Shu, Y., Baither, Y., Gielen, S., Thiele, H., Gummert, J.F., Mohr, F.W. & Schuler, G. 2003. Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 107, 3152-3158.
12. Haram, P.M., Adams, V., Kemi, O.J., Brubakk, A.O., Hambrecht, R., Ellingsen, O. & Wisloff, U. 2006. Time-course of endothelial adaptation following acute and regular exercise. Eur J Cardiovasc Prev Rehabil 13, 585-591.
13. Harvey, P.J., Morris, B.L., Kubo, T., Picton, P.E., Su, W.S., Notarius, C.F. & Floras, J.S. 2005. Hemodynamic after-effects of acute dynamic exercise in sedentary normotensive postmenopausal women. J Hypertens 23, 285-292.
14. Huonker, M., Halle, M. & Keul, J. 1996. Structural and functional adaptations of the cardiovascular system by training. Int J Sports Med 17(Suppl 3), S164-S172.
15. Jones, H., Green, D.J., George, K. & Atkinson, G. 2010. Intermittent exercise abolishes the diurnal variation in endothelial-dependent flow-mediated dilation in humans. Am J Physiol Regul Integr Comp Physiol 298, R427-R432.
16. Joyner, M.J. & Green, D.J. 2009. Exercise protects the cardiovascular system: effects beyond traditional risk factors. J Physiol 587, 5551-5558.
17. Maiorana, A., O'Driscoll, G., Taylor, R. & Green, D. 2003. Exercise and the nitric oxide vasodilator system. Sports Med 33, 1013-1035.
18. Meendering, J.R., Torgrimson, B.N., Miller, N.P., Kaplan, P.F. & Minson, C.T. 2008. Estrogen, medroxyprogesterone acetate, endothelial function, and biomarkers of cardiovascular risk in young women. Am J Physiol Heart Circ Physiol 294, H1630-H1637.
19. Meendering, J.R., Torgrimson, B.N., Miller, N.P., Kaplan, P.F. & Minson, C.T. 2009. Ethinyl estradiol-to-desogestrel ratio impacts endothelial function in young women. Contraception 79, 41-49.
20. Padilla, J., Harris, R.A., Fly, A.D., Rink, L.D. & Wallace, J.P. 2006. The effect of acute exercise on endothelial function following a high-fat meal. Eur J Appl Physiol 98, 256-262.
21. Padilla, J., Harris, R.A. & Wallace, J.P. 2007. Can the measurement of brachial artery flow-mediated dilation be applied to the acute exercise model? Cardiovasc Ultrasound 5, 45.
22. Parker, B.A., Trehearn, T.L. & Meendering, J.R. 2008. Pick Your Poiseuille: normalizing the Shear Stimulus In Studies of Flow-Mediated Dilation. J Appl Physiol 107, 1357-1359.
23. Pyke, K.E. & Tschakovsky, M.E. 2005. The relationship between shear stress and flow-mediated dilatation: implications for the assessment of endothelial function. J Physiol 568, 357-369.
24. Pyke, K.E. & Tschakovsky, M.E. 2007. Peak vs. total reactive hyperemia: which determines the magnitude of flow-mediated dilation? J Appl Physiol 102, 1510-1519.
25. Pyke, K.E., Dwyer, E.M. & Tschakovsky, M.E. 2004. Impact of controlling shear rate on flow-mediated dilation responses in the brachial artery of humans. J Appl Physiol 97, 499-508.
26. Rognmo, O., Bjornstad, T.H., Kahrs, C., Tjonna, A.E., Bye, A., Haram, P.M., Stolen, T., Slordahl, S.A. & Wisloff, U. 2008. Endothelial function in highly endurance-trained men: effects of acute exercise. J Strength Cond Res 22, 535-542.
27. Rundell, K.W., Hoffman, J.R., Caviston, R., Bulbulian, R. & Hollenbach, A.M. 2007. Inhalation of ultrafine and fine particulate matter disrupts systemic vascular function. Inhal Toxicol 19, 133-140.
28. Sawka, M.N., Burke, L.M., Eichner, E.R., Maughan, R.J., Montain, S.J., Stachenfeld, N.S. & American College of Sports Medicine 2007. American College of Sports Medicine position stand. Exercise and fluid replacement. Med Sci Sports Exerc 39, 377-390.
29. Silvestro, A., Scopacasa, F., Oliva, G., de Cristofaro, T., Iuliano, L. & Brevetti, G. 2002. Vitamin C prevents endothelial dysfunction induced by acute exercise in patients with intermittent claudication. Atherosclerosis 165, 277-283.
30. Thijssen, D.H., Black, M.A., Pyke, K.E., Padilla, J., Atkinson, G., Harris, R.A., Parker, B., Widlansky, M.E., Tschakovsky, M.E. & Green, D.J. 2011. Assessment of flow-mediated dilation in humans: a methodological and physiological guideline. Am J Physiol Heart Circ Physiol 300, H2-H12.
31. Tinken, T.M., Thijssen, D.H., Hopkins, N., Dawson, E.A., Cable, N.T. & Green, D.J. 2010. Shear stress mediates endothelial adaptations to exercise training in humans. Hypertension 55, 312-318.