Mechanisms elevating ORMDL3 expression in recurrent wheeze patients: Role of Ets-1, p300 and CREB

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 7, 2012, Pages 1174-1183

  Jin, Rui ^a   Xu, Hua Guo ^a   Yuan, Wen Xiao ^a   Zhuang, Li Li ^a   Liu, Li Fei ^a   Jiang, Li ^a   Zhu, Liang Hua ^a   Liu, Jia Yin ^a   Zhou, Guo Ping ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

CREB; Ets 1; ORMDL3; p300; Transcriptional regulation; Wheeze

Indexed keywords

COMPLEMENTARY DNA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; LUCIFERASE; MESSENGER RNA; PROTEIN P300; TRANSCRIPTION FACTOR ETS 1;

ANKYLOSING SPONDYLITIS; ARTICLE; CHILD; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MOLECULAR CLONING; MUTATIONAL ANALYSIS; ORMDL3 GENE; PRESCHOOL CHILD; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; ULCERATIVE COLITIS; WHEEZING;

ASTHMA; BASE SEQUENCE; CHILD, PRESCHOOL; CREB-BINDING PROTEIN; E1A-ASSOCIATED P300 PROTEIN; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HELA CELLS; HUMANS; INFANT; INFANT, NEWBORN; MALE; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; PROTO-ONCOGENE PROTEIN C-ETS-1; RISK FACTORS; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION;

EID: 84861226876     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.04.007     Document Type: Article

References (39)

1. I.G. Anemaet, J.D. González, M.C. Salgado, M. Giralt, F. Fernández, and I.V. Baanante Transactivation of cytosolic alanine aminotransferase gene promoter by p300 and c-Myb Journal of Molecular Endocrinology 45 2010 119 132
2. M. Arman, J. Calvo, M.E. Trojanowska, P.N. Cockerill, M. Santana, and M. López-Cabrera Transcriptional regulation of human CD5: important role of Ets transcription factors in CD5 expression in T cells Journal of Immunology 172 2004 7519 7529
3. B. Baltus, T.B. van Dijk, E. Caldenhoven, E. Zanders, J.A. Raaijmakers, and J.W. Lammers An AP-1 site in the promoter of the human IL-5R alpha gene is necessary for promoter activity in eosinophilic HL60 cells FEBS Letters 434 1998 251 254
4. H. Bisgaard, M.N. Hermansen, L. Loland, L.B. Halkjaer, and F. Buchvald Intermittent inhaled corticosteroids in infants with episodic wheezing New England Journal of Medicine 354 2006 1998 2005
5. N. Bitomsky, M. Böhm, and K.H. Klempnauer Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun Oncogene 23 2004 7484 7493
6. S.G. Blumenthal, G. Aichele, T. Wirth, A.P. Czernilofsky, A. Nordheim, and J. Dittmer Regulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1 Journal of Biological Chemistry 274 1999 12910 12916
7. E.V. Bräuner, S. Loft, O. Raaschou-Nielsen, U. Vogel, P.S. Andersen, and M. Sorensen Effects of a 17q21 chromosome gene variant, tobacco smoke and furred pets on infant wheeze Genes and Immunity 2011 10.1038/gene.2011.51
8. D.K. Breslow, S.R. Collins, B. Bodenmiller, R. Aebersold, K. Simons, and A. Shevchenko Orm family proteins mediate sphingolipid homeostasis Nature 463 2010 1048 1053
9. J.E. Butler, and J.T. Kadonaga The RNA polymerase II core promoter: a key component in the regulation of gene expression Genes and Development 16 2002 2583 2592
10. G. Cantero-Recasens, C. Fandos, F. Rubio-Moscardo, M.A. Valverde, and R. Vicente The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress Human Molecular Genetics 19 2010 111 121
11. A.G. Eliopoulos, C.D. Dumitru, C.C. Wang, J. Cho, and P.N. Tsichlis Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals EMBO Journal 21 2002 4831 4840
12. J. Galanter, S. Choudhry, C. Eng, S. Nazario, J.R. Rodríguez- Santana, and J. Casal ORMDL3 gene is associated with asthma in three ethnically diverse populations American Journal of Respiratory and Critical Care Medicine 177 2008 1194 1200
13. G. Henkel, and M.A. Brown PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer Proceedings of the National Academy of Sciences of the United States of America 91 1994 7737 7741
14. T. Hirota, M. Harada, M. Sakashita, S. Doi, A. Miyatake, and K. Fujita Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population Journal of Allergy and Clinical Immunology 121 2008 769 770
15. L. Hjelmqvist, M. Tuson, G. Marfany, E. Herrero, S. Balcells, and R. Gonzàlez-Duarte ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins Genome Biology 3 2002 RESEARCH0027
16. T. Juven-Gershon, J.Y. Hsu, and J.T. Kadonaga Perspectives on the RNA polymerase II core promoter Biochemical Society Transactions 34 2006 1047 1050
17. T. Juven-Gershon, J.Y. Hsu, J.W. Theisen, and J.T. Kadonaga The RNA polymerase II core promoter - the gateway to transcription Current Opinion in Cell Biology 20 2008 253 259
18. M.L. Kingsley-Kallesen, D. Kelly, and A. Rizzino Transcriptional regulation of the transforming growth factor-beta2 promoter by cAMP-responsive element-binding protein (CREB) and activating transcription factor-1 (ATF-1) is modulated by protein kinases and the coactivators p300 and CREB-binding protein Journal of Biological Chemistry 274 1999 34020 34028
19. P. Kumar, and K.N. Pandey Cooperative activation of Npr1 gene transcription and expression by interaction of Ets-1 and p300 Hypertension 54 2009 172 178
20. D. Laukens, M. Georges, C. Libioulle, C. Sandor, M. Mni, and B. Vander Cruyssen Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis PLoS One 5 2010 e13795
21. T.F. Leung, H.Y. Sy, M.C. Ng, I.H. Chan, G.W. Wong, and N.L. Tang Asthma and atopy are associated with chromosome 17q21 markers in Chinese children Allergy 64 2009 621 628
22. C. Liu, J. Lu, J. Tan, L. Li, and B. Huang Human interleukin-5 expression is synergistically regulated by histone acetyltransferase CBP/p300 and transcription factors C/EBP, NF-AT and AP-1 Cytokine 27 2004 93 100
23. A.M. Madore, K. Tremblay, T.J. Hudson, and C. Laprise Replication of an association between 17q21 SNPs and asthma in a French-Canadian familial collection Human Genetics 123 2008 93 95
24. 2-adrenergic receptors in vivo Journal of Clinical Investigation 96 1995 99 106
25. F.D. Martinez, A.L. Wright, L.M. Taussig, C.J. Holberg, M. Halonen, and W.J. Morgan Asthma and wheezing in the first six years of life. The Group Health Medical Associates New England Journal of Medicine 332 1995 133 138
26. M. Masoli, D. Fabian, S. Holt, and R. Beasley Global Initiative for Asthma (GINA) Program. The global burden of asthma: executive summary of the GINA Dissemination Committee report Allergy 59 2004 469 478
27. D.P. McGovern, A. Gardet, L. Törkvist, P. Goyette, J. Essers, and K.D. Taylor Genome-wide association identifies multiple ulcerative colitis susceptibility loci Nature Genetics 42 2010 332 337
28. L.H. McKinlay, M.J. Tymms, R.S. Thomas, A. Seth, S. Hasthorpe, and P.J. Hertzog The role of Ets-1 in mast cell granulocytemacrophage colony-stimulating factor expression and activation Journal of Immunology 161 1998 4098 4105
29. M.F. Moffatt, M. Kabesch, L. Liang, A.L. Dixon, D. Strachan, and S. Heath Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma Nature 448 2007 470 473
30. Y. Nakamura, S. Esnault, T. Maeda, E.A. Kelly, J.S. Malter, and N.N. Jarjour Ets-1 regulates TNF-alpha-induced matrix metalloproteinase-9 and tenascin expression in primary bronchial fibroblasts Journal of Immunology 172 2004 1945 1952
31. 2- adrenoreceptor messenger RNA with prolonged in vivo infusion of isoprenaline European Journal of Pharmacology 247 1993 131 138
32. M.J. Peters, I.M. Adcock, C.R. Brown, and P.J. Barnes β-Adrenoceptor agonists interfere with glucocorticoid receptor DNA binding in rat lung European Journal of Pharmacology 289 1995 275 281
33. G.A. Preston, D. Srinivasan, and J.C. Barrett Apoptotic response to growth factor deprivation involves cooperative interactions between c-Fos and p300 Cell Death and Differentiation 7 2000 215 226
34. R. Ravi, B. Mookerjee, Y. van Hensbergen, G.C. Bedi, A. Giordano, and W.S. El-Deiry p53-mediated repression of nuclear factor-kappaB RelA via the transcriptional integrator p300 Cancer Research 58 1998 4531 4536
35. T.L. Rudge, and L.F. Johnson Synergistic activation of the TATA-less mouse thymidylate synthase promoter by the Ets transcription factor GABP and Sp1 Experimental Cell Research 274 2002 45 55
36. N.M. Saleh, S.M. Raj, D.J. Smyth, C. Wallace, J.M. Howson, and L. Bell Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes Diabetes/Metabolism Research and Reviews 27 2011 838 843
37. J.M. Strempel, R. Grenningloh, I.C. Ho, and D. Vercelli Phylogenetic and functional analysis identifies Ets-1 as a novel regulator of the Th2 cytokine gene locus Journal of Immunology 184 2010 1309 1316
38. H.G. Xu, W. Ren, L. Zou, Y. Wang, R. Jin, and G.P. Zhou Direct repression of the human IRF-3 promoter by E2F1 Immunogenetics 63 2011 189 196
39. C. Yang, L.H. Shapiro, M. Rivera, A. Kumar, and P.K. Brindle A role for CREB binding protein and p300 transcriptional coactivators in Ets-1 transactivation functions Molecular and Cellular Biology 18 1998 2218 2229