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Volumn 421, Issue 4, 2012, Pages 768-772

Autophagy in the intestinal epithelium is not involved in the pathogenesis of intestinal tumors

Author keywords

APC; Autophagy; Intestinal epithelium; Intestinal tumor

Indexed keywords

BECLIN 1; DNA METHYLTRANSFERASE 1; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 84861225994     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.04.081     Document Type: Article
Times cited : (9)

References (31)
  • 1
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: molecular mechanisms and biological functions of autophagy
    • Levine B., Klionsky D.J. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev. Cell. 2004, 6:463-477.
    • (2004) Dev. Cell. , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 3
    • 0023065242 scopus 로고
    • Intracellular protein catabolism and its control during nutrient deprivation and supply
    • Mortimore G.E., Poso A.R. Intracellular protein catabolism and its control during nutrient deprivation and supply. Annu. Rev. Nutr. 1987, 7:539-564.
    • (1987) Annu. Rev. Nutr. , vol.7 , pp. 539-564
    • Mortimore, G.E.1    Poso, A.R.2
  • 4
    • 0027424777 scopus 로고
    • Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
    • Tsukada M., Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 1993, 333:169-174.
    • (1993) FEBS Lett. , vol.333 , pp. 169-174
    • Tsukada, M.1    Ohsumi, Y.2
  • 5
    • 11144245626 scopus 로고    scopus 로고
    • The role of autophagy during the early neonatal starvation period
    • Kuma A., Hatano M., Matsui M., et al. The role of autophagy during the early neonatal starvation period. Nature 2004, 432:1032-1036.
    • (2004) Nature , vol.432 , pp. 1032-1036
    • Kuma, A.1    Hatano, M.2    Matsui, M.3
  • 6
    • 21044455137 scopus 로고    scopus 로고
    • Impairment of starvation-induced and constitutive autophagy in atg7-deficient mice
    • Komatsu M., Waguri S., Ueno T., et al. Impairment of starvation-induced and constitutive autophagy in atg7-deficient mice. J. Cell Biol. 2005, 169:425-434.
    • (2005) J. Cell Biol. , vol.169 , pp. 425-434
    • Komatsu, M.1    Waguri, S.2    Ueno, T.3
  • 7
    • 33750624967 scopus 로고    scopus 로고
    • Mitochondrial signaling, tor, and life span
    • Schieke S.M., Finkel T. Mitochondrial signaling, tor, and life span. Biol. Chem. 2006, 387:1357-1361.
    • (2006) Biol. Chem. , vol.387 , pp. 1357-1361
    • Schieke, S.M.1    Finkel, T.2
  • 8
    • 0042823543 scopus 로고    scopus 로고
    • Genetic analysis of tor signaling in drosophila
    • Neufeld T.P. Genetic analysis of tor signaling in drosophila. Curr. Top. Microbiol. Immunol. 2004, 279:139-152.
    • (2004) Curr. Top. Microbiol. Immunol. , vol.279 , pp. 139-152
    • Neufeld, T.P.1
  • 9
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • Gutierrez M.G., Master S.S., Singh S.B., et al. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004, 119:753-766.
    • (2004) Cell , vol.119 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3
  • 10
    • 33748506089 scopus 로고    scopus 로고
    • Human IRGM induces autophagy to eliminate intracellular mycobacteria
    • Singh S.B., Davis A.S., Taylor G.A., et al. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 2006, 313:1438-1441.
    • (2006) Science , vol.313 , pp. 1438-1441
    • Singh, S.B.1    Davis, A.S.2    Taylor, G.A.3
  • 11
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 12
    • 79955492012 scopus 로고    scopus 로고
    • Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells
    • Inami Y., Waguri S., Sakamoto A., et al. Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. J. Cell Biol. 2011, 193:275-284.
    • (2011) J. Cell Biol. , vol.193 , pp. 275-284
    • Inami, Y.1    Waguri, S.2    Sakamoto, A.3
  • 13
    • 0345166111 scopus 로고    scopus 로고
    • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
    • Yue Z., Jin S., Yang C., et al. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc. Natl. Acad. Sci. USA 2003, 100:15077-15082.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 15077-15082
    • Yue, Z.1    Jin, S.2    Yang, C.3
  • 14
    • 9144240441 scopus 로고    scopus 로고
    • Promotion of tumorigenesis by heterozygous disruption of the beclin1 autophagy gene
    • Qu X., Yu J., Bhagat G., et al. Promotion of tumorigenesis by heterozygous disruption of the beclin1 autophagy gene. J. Clin. Invest. 2003, 112:1809-1820.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1809-1820
    • Qu, X.1    Yu, J.2    Bhagat, G.3
  • 15
    • 33745713171 scopus 로고    scopus 로고
    • Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
    • Degenhardt K., Mathew R., Beaudoin B., et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 2006, 10:51-64.
    • (2006) Cancer Cell , vol.10 , pp. 51-64
    • Degenhardt, K.1    Mathew, R.2    Beaudoin, B.3
  • 16
    • 79952228407 scopus 로고    scopus 로고
    • Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
    • Guo J.Y., Chen H.Y., Mathew R., et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev. 2011, 25:460-470.
    • (2011) Genes Dev. , vol.25 , pp. 460-470
    • Guo, J.Y.1    Chen, H.Y.2    Mathew, R.3
  • 17
    • 79551497661 scopus 로고    scopus 로고
    • The antidepressants maprotiline and fluoxetine induce Type II autophagic cell death in drug-resistant Burkitt's lymphoma
    • Cloonan S.M., Williams D.C. The antidepressants maprotiline and fluoxetine induce Type II autophagic cell death in drug-resistant Burkitt's lymphoma. Int. J. Cancer 2010, 128:1712-1723.
    • (2010) Int. J. Cancer , vol.128 , pp. 1712-1723
    • Cloonan, S.M.1    Williams, D.C.2
  • 18
    • 61349141302 scopus 로고    scopus 로고
    • Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2
    • Feldman M.E., Apsel B., Uotila A., et al. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol. 2009, 7:e38.
    • (2009) PLoS Biol. , vol.7
    • Feldman, M.E.1    Apsel, B.2    Uotila, A.3
  • 19
    • 79151474603 scopus 로고    scopus 로고
    • Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-κB activation
    • Fujishima Y., Nishiumi S., Masuda A., et al. Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-κB activation. Arch. Biochem. Biophys. 2011, 506:223-235.
    • (2011) Arch. Biochem. Biophys. , vol.506 , pp. 223-235
    • Fujishima, Y.1    Nishiumi, S.2    Masuda, A.3
  • 20
    • 80053634368 scopus 로고    scopus 로고
    • The dynamic nature of autophagy in cancer
    • Kimmelman A.C. The dynamic nature of autophagy in cancer. Genes Dev. 2011, 25:1999-2010.
    • (2011) Genes Dev. , vol.25 , pp. 1999-2010
    • Kimmelman, A.C.1
  • 21
    • 0000906170 scopus 로고    scopus 로고
    • Induction of autophagy and inhibition of tumorigenesis by beclin1
    • Liang X.H., Jackson S., Seaman M., et al. Induction of autophagy and inhibition of tumorigenesis by beclin1. Nature 1999, 402:672-676.
    • (1999) Nature , vol.402 , pp. 672-676
    • Liang, X.H.1    Jackson, S.2    Seaman, M.3
  • 22
    • 69949106925 scopus 로고    scopus 로고
    • The double-edged sword of autophagy modulation in cancer
    • White E., DiPaola R.S. The double-edged sword of autophagy modulation in cancer. Clin. Cancer Res. 2009, 15:5308-5316.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 5308-5316
    • White, E.1    DiPaola, R.S.2
  • 23
    • 79952229430 scopus 로고    scopus 로고
    • Pancreatic cancers require autophagy for tumor growth
    • Yang S., Wang X., Contino G., et al. Pancreatic cancers require autophagy for tumor growth. Genes Dev. 2011, 25:717-729.
    • (2011) Genes Dev. , vol.25 , pp. 717-729
    • Yang, S.1    Wang, X.2    Contino, G.3
  • 24
    • 79959735042 scopus 로고    scopus 로고
    • Mutational and expressional analyses of ATG5, an autophagy-related gene, in gastrointestinal cancers
    • An C.H., Kim M.S., Yoo N.J., et al. Mutational and expressional analyses of ATG5, an autophagy-related gene, in gastrointestinal cancers. Pathol. Res. Pract. 2011, 207:433-437.
    • (2011) Pathol. Res. Pract. , vol.207 , pp. 433-437
    • An, C.H.1    Kim, M.S.2    Yoo, N.J.3
  • 25
    • 55849126198 scopus 로고    scopus 로고
    • Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma
    • Coppola D., Khalil F., Eschrich S.A., et al. Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma. Cancer 2008, 113:2665-2670.
    • (2008) Cancer , vol.113 , pp. 2665-2670
    • Coppola, D.1    Khalil, F.2    Eschrich, S.A.3
  • 26
    • 35448980704 scopus 로고    scopus 로고
    • Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation
    • Sato K., Tsuchihara K., Fujii S., et al. Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res. 2007, 67:9677-9684.
    • (2007) Cancer Res. , vol.67 , pp. 9677-9684
    • Sato, K.1    Tsuchihara, K.2    Fujii, S.3
  • 27
    • 84861705489 scopus 로고    scopus 로고
    • Regulation of the metabolite profile by an APC gene mutation in colorectal cancer
    • in press.
    • T. Yoshie, S. Nishiumi, Y. Izumi, et al., Regulation of the metabolite profile by an APC gene mutation in colorectal cancer, Cancer Sci., in press.
    • Cancer Sci.
    • Yoshie, T.1    Nishiumi, S.2    Izumi, Y.3
  • 28
    • 66349095388 scopus 로고    scopus 로고
    • Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry
    • Hirayama A., Kami K., Sugimoto M., et al. Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry. Cancer Res. 2009, 69:4918-4925.
    • (2009) Cancer Res. , vol.69 , pp. 4918-4925
    • Hirayama, A.1    Kami, K.2    Sugimoto, M.3
  • 29
    • 34250634050 scopus 로고    scopus 로고
    • Targeting aberrant chromatin structure in colorectal carcinomas
    • Konishi K., Issa J.P. Targeting aberrant chromatin structure in colorectal carcinomas. Cancer J. 2007, 13:49-55.
    • (2007) Cancer J. , vol.13 , pp. 49-55
    • Konishi, K.1    Issa, J.P.2
  • 30
    • 0035863455 scopus 로고    scopus 로고
    • DNA methyltransferase expression and DNA methylation of CpG islands and pericentromeric satellite regions in human colorectal and stomach cancers
    • Kanai Y., Ushijima S., Kondo Y., et al. DNA methyltransferase expression and DNA methylation of CpG islands and pericentromeric satellite regions in human colorectal and stomach cancers. Int. J. Cancer 2001, 91:205-212.
    • (2001) Int. J. Cancer , vol.91 , pp. 205-212
    • Kanai, Y.1    Ushijima, S.2    Kondo, Y.3
  • 31
    • 0029001154 scopus 로고
    • Suppression of intestinal neoplasia by DNA hypomethylation
    • Laird P.W., Jackson-Grusby L., Fazeli A., et al. Suppression of intestinal neoplasia by DNA hypomethylation. Cell 1995, 81:197-205.
    • (1995) Cell , vol.81 , pp. 197-205
    • Laird, P.W.1    Jackson-Grusby, L.2    Fazeli, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.