-
1
-
-
1842583789
-
Development by self-digestion: molecular mechanisms and biological functions of autophagy
-
Levine B., Klionsky D.J. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev. Cell. 2004, 6:463-477.
-
(2004)
Dev. Cell.
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
3
-
-
0023065242
-
Intracellular protein catabolism and its control during nutrient deprivation and supply
-
Mortimore G.E., Poso A.R. Intracellular protein catabolism and its control during nutrient deprivation and supply. Annu. Rev. Nutr. 1987, 7:539-564.
-
(1987)
Annu. Rev. Nutr.
, vol.7
, pp. 539-564
-
-
Mortimore, G.E.1
Poso, A.R.2
-
4
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
-
Tsukada M., Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 1993, 333:169-174.
-
(1993)
FEBS Lett.
, vol.333
, pp. 169-174
-
-
Tsukada, M.1
Ohsumi, Y.2
-
5
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
Kuma A., Hatano M., Matsui M., et al. The role of autophagy during the early neonatal starvation period. Nature 2004, 432:1032-1036.
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
-
6
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in atg7-deficient mice
-
Komatsu M., Waguri S., Ueno T., et al. Impairment of starvation-induced and constitutive autophagy in atg7-deficient mice. J. Cell Biol. 2005, 169:425-434.
-
(2005)
J. Cell Biol.
, vol.169
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
-
7
-
-
33750624967
-
Mitochondrial signaling, tor, and life span
-
Schieke S.M., Finkel T. Mitochondrial signaling, tor, and life span. Biol. Chem. 2006, 387:1357-1361.
-
(2006)
Biol. Chem.
, vol.387
, pp. 1357-1361
-
-
Schieke, S.M.1
Finkel, T.2
-
8
-
-
0042823543
-
Genetic analysis of tor signaling in drosophila
-
Neufeld T.P. Genetic analysis of tor signaling in drosophila. Curr. Top. Microbiol. Immunol. 2004, 279:139-152.
-
(2004)
Curr. Top. Microbiol. Immunol.
, vol.279
, pp. 139-152
-
-
Neufeld, T.P.1
-
9
-
-
10944253145
-
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
-
Gutierrez M.G., Master S.S., Singh S.B., et al. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004, 119:753-766.
-
(2004)
Cell
, vol.119
, pp. 753-766
-
-
Gutierrez, M.G.1
Master, S.S.2
Singh, S.B.3
-
10
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
Singh S.B., Davis A.S., Taylor G.A., et al. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 2006, 313:1438-1441.
-
(2006)
Science
, vol.313
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, A.S.2
Taylor, G.A.3
-
11
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
12
-
-
79955492012
-
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells
-
Inami Y., Waguri S., Sakamoto A., et al. Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. J. Cell Biol. 2011, 193:275-284.
-
(2011)
J. Cell Biol.
, vol.193
, pp. 275-284
-
-
Inami, Y.1
Waguri, S.2
Sakamoto, A.3
-
13
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z., Jin S., Yang C., et al. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc. Natl. Acad. Sci. USA 2003, 100:15077-15082.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
-
14
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin1 autophagy gene
-
Qu X., Yu J., Bhagat G., et al. Promotion of tumorigenesis by heterozygous disruption of the beclin1 autophagy gene. J. Clin. Invest. 2003, 112:1809-1820.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
-
15
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt K., Mathew R., Beaudoin B., et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 2006, 10:51-64.
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
-
16
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
-
Guo J.Y., Chen H.Y., Mathew R., et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev. 2011, 25:460-470.
-
(2011)
Genes Dev.
, vol.25
, pp. 460-470
-
-
Guo, J.Y.1
Chen, H.Y.2
Mathew, R.3
-
17
-
-
79551497661
-
The antidepressants maprotiline and fluoxetine induce Type II autophagic cell death in drug-resistant Burkitt's lymphoma
-
Cloonan S.M., Williams D.C. The antidepressants maprotiline and fluoxetine induce Type II autophagic cell death in drug-resistant Burkitt's lymphoma. Int. J. Cancer 2010, 128:1712-1723.
-
(2010)
Int. J. Cancer
, vol.128
, pp. 1712-1723
-
-
Cloonan, S.M.1
Williams, D.C.2
-
18
-
-
61349141302
-
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2
-
Feldman M.E., Apsel B., Uotila A., et al. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol. 2009, 7:e38.
-
(2009)
PLoS Biol.
, vol.7
-
-
Feldman, M.E.1
Apsel, B.2
Uotila, A.3
-
19
-
-
79151474603
-
Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-κB activation
-
Fujishima Y., Nishiumi S., Masuda A., et al. Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-κB activation. Arch. Biochem. Biophys. 2011, 506:223-235.
-
(2011)
Arch. Biochem. Biophys.
, vol.506
, pp. 223-235
-
-
Fujishima, Y.1
Nishiumi, S.2
Masuda, A.3
-
20
-
-
80053634368
-
The dynamic nature of autophagy in cancer
-
Kimmelman A.C. The dynamic nature of autophagy in cancer. Genes Dev. 2011, 25:1999-2010.
-
(2011)
Genes Dev.
, vol.25
, pp. 1999-2010
-
-
Kimmelman, A.C.1
-
21
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin1
-
Liang X.H., Jackson S., Seaman M., et al. Induction of autophagy and inhibition of tumorigenesis by beclin1. Nature 1999, 402:672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
-
22
-
-
69949106925
-
The double-edged sword of autophagy modulation in cancer
-
White E., DiPaola R.S. The double-edged sword of autophagy modulation in cancer. Clin. Cancer Res. 2009, 15:5308-5316.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 5308-5316
-
-
White, E.1
DiPaola, R.S.2
-
23
-
-
79952229430
-
Pancreatic cancers require autophagy for tumor growth
-
Yang S., Wang X., Contino G., et al. Pancreatic cancers require autophagy for tumor growth. Genes Dev. 2011, 25:717-729.
-
(2011)
Genes Dev.
, vol.25
, pp. 717-729
-
-
Yang, S.1
Wang, X.2
Contino, G.3
-
24
-
-
79959735042
-
Mutational and expressional analyses of ATG5, an autophagy-related gene, in gastrointestinal cancers
-
An C.H., Kim M.S., Yoo N.J., et al. Mutational and expressional analyses of ATG5, an autophagy-related gene, in gastrointestinal cancers. Pathol. Res. Pract. 2011, 207:433-437.
-
(2011)
Pathol. Res. Pract.
, vol.207
, pp. 433-437
-
-
An, C.H.1
Kim, M.S.2
Yoo, N.J.3
-
25
-
-
55849126198
-
Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma
-
Coppola D., Khalil F., Eschrich S.A., et al. Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma. Cancer 2008, 113:2665-2670.
-
(2008)
Cancer
, vol.113
, pp. 2665-2670
-
-
Coppola, D.1
Khalil, F.2
Eschrich, S.A.3
-
26
-
-
35448980704
-
Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation
-
Sato K., Tsuchihara K., Fujii S., et al. Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res. 2007, 67:9677-9684.
-
(2007)
Cancer Res.
, vol.67
, pp. 9677-9684
-
-
Sato, K.1
Tsuchihara, K.2
Fujii, S.3
-
27
-
-
84861705489
-
Regulation of the metabolite profile by an APC gene mutation in colorectal cancer
-
in press.
-
T. Yoshie, S. Nishiumi, Y. Izumi, et al., Regulation of the metabolite profile by an APC gene mutation in colorectal cancer, Cancer Sci., in press.
-
Cancer Sci.
-
-
Yoshie, T.1
Nishiumi, S.2
Izumi, Y.3
-
28
-
-
66349095388
-
Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry
-
Hirayama A., Kami K., Sugimoto M., et al. Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry. Cancer Res. 2009, 69:4918-4925.
-
(2009)
Cancer Res.
, vol.69
, pp. 4918-4925
-
-
Hirayama, A.1
Kami, K.2
Sugimoto, M.3
-
29
-
-
34250634050
-
Targeting aberrant chromatin structure in colorectal carcinomas
-
Konishi K., Issa J.P. Targeting aberrant chromatin structure in colorectal carcinomas. Cancer J. 2007, 13:49-55.
-
(2007)
Cancer J.
, vol.13
, pp. 49-55
-
-
Konishi, K.1
Issa, J.P.2
-
30
-
-
0035863455
-
DNA methyltransferase expression and DNA methylation of CpG islands and pericentromeric satellite regions in human colorectal and stomach cancers
-
Kanai Y., Ushijima S., Kondo Y., et al. DNA methyltransferase expression and DNA methylation of CpG islands and pericentromeric satellite regions in human colorectal and stomach cancers. Int. J. Cancer 2001, 91:205-212.
-
(2001)
Int. J. Cancer
, vol.91
, pp. 205-212
-
-
Kanai, Y.1
Ushijima, S.2
Kondo, Y.3
-
31
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA hypomethylation
-
Laird P.W., Jackson-Grusby L., Fazeli A., et al. Suppression of intestinal neoplasia by DNA hypomethylation. Cell 1995, 81:197-205.
-
(1995)
Cell
, vol.81
, pp. 197-205
-
-
Laird, P.W.1
Jackson-Grusby, L.2
Fazeli, A.3
|