Determination of total and unbound sufentanil in human plasma by ultrafiltration and LC-MS/MS: Application to clinical pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis

Volumn 66, Issue , 2012, Pages 306-313

  Saari, Teijo I ^a   Fechner, Jörg ^a   Ihmsen, Harald ^a   Schüttler, Jürgen ^a   Jeleazcov, Christian ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Liquid chromatography; Mass spectrometry; Pharmacokinetic; Sufentanil; Target controlled infusion (TCI); Unbound

Indexed keywords

DEUTERIUM OXIDE; PROPOFOL; SUFENTANIL; SUFENTANIL CITRATE;

ACCURACY; ARTICLE; CONTINUOUS INFUSION; CORONARY ARTERY BYPASS GRAFT; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; HUMAN; HUMAN EXPERIMENT; LIMIT OF QUANTITATION; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; SUBSTITUTION REACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAFILTRATION;

ANALGESICS, OPIOID; CALIBRATION; CHROMATOGRAPHY, LIQUID; CORONARY ARTERY BYPASS; HUMANS; LIMIT OF DETECTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUFENTANIL; TANDEM MASS SPECTROMETRY; ULTRAFILTRATION;

EID: 84861220823     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.03.050     Document Type: Article

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