HPLC-UV assay for monitoring total and unbound mycophenolic acid concentrations in children

Biomedical Chromatography

Volumn 23, Issue 1, 2009, Pages 92-100

  Zeng, L ^a,b   Nath, Christan E ^b   Shaw, P J ^a,c   Earl, J W ^b   McLachlan, A J ^a,d  

^a UNIVERSITY OF SYDNEY   (Australia)

^b The Children's Hospital Westmead   (Australia)

^c CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^d Department of Microbiology and Infectious Diseases   (Australia)

Author keywords

Bone marrow transplant; Children; HPLC UV assay; Mycophenolic acid; Pharmacokinetics; Protein binding; Ultrafiltration

Indexed keywords

BIOCHEMISTRY; BONE; PEDIATRICS; PROTEINS; SODIUM COMPOUNDS; ULTRAFILTRATION;

ACID CONCENTRATIONS; BONE MARROW TRANSPLANT; CHILD; HPLC METHOD; HPLC-UV; HPLC-UV ASSAY; HUMAN PLASMAS; MYCOPHENOLIC ACIDS; PROTEIN-BINDING; SIMPLE++;

PHARMACOKINETICS;

MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

ADOLESCENT; AREA UNDER THE CURVE; ARTICLE; BONE MARROW TRANSPLANTATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG ISOLATION; DRUG RECEPTOR BINDING; DRUG STABILITY; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFANT; LIGHT ABSORPTION; PRECIPITATION; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; ULTRAFILTRATION; ULTRAVIOLET SPECTROSCOPY; VALIDATION PROCESS;

EID: 59949101460     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1088     Document Type: Article

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