Quantitative determination of total and unbound paclitaxel in human plasma following Abraxane treatment

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 862, Issue 1-2, 2008, Pages 213-218

  Gardner, Erin R ^a   Dahut, William ^b   Figg, William D ^b  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Albumin; Anticancer; Formulation; Free fraction; LC MS MS; Nanoparticle; Paclitaxel; Taxane; Unbound fraction

Indexed keywords

BIOASSAY; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NANOPARTICLES; PRECIPITATION (CHEMICAL); PROTEINS;

ABRAXANE TREATMENT; ALBUMIN NANOPARTICLES; ANTICANCER; PACLITAXEL; PROTEIN PRECIPITATION;

PLASMA (HUMAN);

PACLITAXEL;

AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STABILITY; ELECTROSPRAY; HUMAN; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; SERUM; TANDEM MASS SPECTROMETRY;

ALBUMINS; ANTINEOPLASTIC AGENTS; CALIBRATION; HUMANS; PACLITAXEL; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 38649102812     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.12.013     Document Type: Article

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