Editorial: Gauging the risk of arrhythmic death by common genetic variants resurgence of the sinister QT: Circ Cardiovasc Genet

Circulation: Cardiovascular Genetics

Volumn 4, Issue 3, 2011, Pages 221-222

  Chopra, Nagesh ^a   Knollmann, Björn C ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ION CHANNEL;

EDITORIAL; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HEART ARRHYTHMIA; HEART REPOLARIZATION; HUMAN; MORTALITY; PRIORITY JOURNAL; QT INTERVAL; QT PROLONGATION; RISK ASSESSMENT; SUDDEN DEATH; TORSADE DES POINTES; CARDIOVASCULAR DISEASE; ELECTROCARDIOGRAPHY; GENETICS; NOTE; PATHOPHYSIOLOGY; RISK FACTOR;

CARDIOVASCULAR DISEASES; DEATH, SUDDEN, CARDIAC; ELECTROCARDIOGRAPHY; GENOTYPE; HUMANS; RISK FACTORS;

EID: 80052711338     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.111.960328     Document Type: Editorial

References (14)

1. Noseworthy PA, Havulinna AS, Porthan K, Lahtinen AM, Jula A, Karhunen PJ, Perola M, Oikarinen L, Kontula KK, Salomaa V, Newton-Cheh C. Common genetic variants, QT interval, and sudden cardiac death in a Finnish population-based study. Circ Cardiovasc Genet. 2011;4:305-311.
2. Straus SM, Kors JA, De Bruin ML, van der Hooft CS, Hofman A, Heeringa J, Deckers JW, Kingma JH, Sturkenboom MC, Stricker BH, Witteman JC. Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol. 2006;47:362-367. (Pubitemid 43063255)
3. Hong Y, Rautaharju PM, Hopkins PN, Arnett DK, Djousse L, Pankow JS, Sholinsky P, Rao DC, Province MA. Familial aggregation of QT-interval variability in a general population: results from the NHLBI Family Heart Study. Clin Genet. 2001;59:171-177. (Pubitemid 32229772)
4. Porthan K, Viitasalo M, Jula A, Reunanen A, Rapola J, Vaananen H, Nieminen MS, Toivonen L, Salomaa V, Oikarinen L. Predictive value of electrocardiographic QT interval and T-wave morphology parameters for all-cause and cardiovascular mortality in a general population sample. Heart Rhythm. 2009;6:1202-1208.
5. Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE, Marban E, O'Donnell CJ, Hirschhorn JN, Kaab S, Spooner PM, Meitinger T, Chakravarti A. A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat Genet. 2006;38:644-651. (Pubitemid 43927305)
6. Beyerbach DM, Kovacs RJ, Dmitrienko AA, Rebhun DM, Zipes DP. Heart rate-corrected QT interval in men increases during winter months. Heart Rhythm. 2007;4:277-281. (Pubitemid 46323461)
7. Kannankeril PJ, Roden DM. When should QT be measured? Summer solstice or Christmas Eve? Heart Rhythm. 2007;4:282-283. (Pubitemid 46323469)
8. Kattainen A, Salomaa V, Harkanen T, Jula A, Kaaja R, Kesaniemi YA, Kahonen M, Moilanen L, Nieminen MS, Aromaa A, Reunanen A. Coronary heart disease: from a disease of middle-aged men in the late 1970s to a disease of elderly women in the 2000s. Eur Heart J. 2006; 27:296-301. (Pubitemid 43100024)
9. Karjalainen J, Viitasalo M, Manttari M, Manninen V. Relation between QT intervals and heart rates from 40 to 120 beats/min in rest electrocardiograms of men and a simple method to adjust QT interval values. J Am Coll Cardiol. 1994;23:1547-1553. (Pubitemid 24182117)
10. Newton-Cheh C, Eijgelsheim M, Rice KM, de Bakker PI, Yin X, Estrada K, Bis JC, Marciante K, Rivadeneira F, Noseworthy PA, Sotoodehnia N, Smith NL, Rotter JI, Kors JA, Witteman JC, Hofman A, Heckbert SR, O'Donnell CJ, Uitterlinden AG, Psaty BM, Lumley T, Larson MG, Stricker BH. Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet. 2009;41:399-406.
11. Pfeufer A, Sanna S, Arking DE, Muller M, Gateva V, Fuchsberger C, Ehret GB, Orru M, Pattaro C, Kottgen A, Perz S, Usala G, Barbalic M, Li M, Putz B, Scuteri A, Prineas RJ, Sinner MF, Gieger C, Najjar SS, Kao WH, Muhleisen TW, Dei M, Happle C, Mohlenkamp S, Crisponi L, Erbel R, Jockel KH, Naitza S, Steinbeck G, Marroni F, Hicks AA, Lakatta E, Muller-Myhsok B, Pramstaller PP, Wichmann HE, Schlessinger D, Boerwinkle E, Meitinger T, Uda M, Coresh J, Kaab S, Abecasis GR, Chakravarti A. Common variants at ten loci modulate the QT interval duration in the QTSCD Study. Nat Genet. 2009;41:407-414.
12. January CT, Riddle JM. Early afterdepolarizations: mechanism of induction and block: a role for L-type Ca2-current. Circ Res. 1989;64: 977-990. (Pubitemid 19117651)
13. Antzelevitch C, Fish J. Electrical heterogeneity within the ventricular wall. Basic Res Cardiol. 2001;96:517-527. (Pubitemid 33121024)
14. Roden DM. Long QT syndrome: reduced repolarization reserve and the genetic link. J Intern Med. 2006;259:59-69.