The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo

Journal of Cell Science

Volumn 125, Issue 4, 2012, Pages 1048-1057

  Brachner, Andreas ^a   Braun, Juliane ^a   Ghodgaonkar, Medini ^b   Castor, Dennis ^b   Zlopasa, Livija ^a   Ehrlich, Veronika ^c   Jiricny, Josef ^b   Gotzmann, Josef ^a   Knasmüller, Siegfried ^c   Foisner, Roland ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Chromatin; DNA damage; GIY YIG endonucleases; LEM domain; Nuclear envelope

Indexed keywords

ANKYRIN REPEAT LAMINA ASSOCIATED POLYPEPTIDE EMERIN MAN1 DOMAIN CONTAINING PROTEIN 1; ENDONUCLEASE; LAMINA ASSOCIATED POLYPEPTIDE EMERIN MAN1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DNA CLEAVAGE; DNA DAMAGE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF;

AMINO ACID MOTIFS; ANIMALS; CELL LINE; CELL NUCLEUS; CONSERVED SEQUENCE; CYTOPLASM; DNA CLEAVAGE; DNA DAMAGE; ENDONUCLEASES; GENE EXPRESSION PROFILING; HEMATOPOIETIC SYSTEM; HUMANS; IMMUNOPRECIPITATION; ORGAN SPECIFICITY; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EUKARYOTA; MAMMALIA; METAZOA;

EID: 84861210493     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.098392     Document Type: Article

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