Treatment with IL-7 prevents the decline of circulating CD4+ T cells during the acute phase of SIV infection in rhesus macaques

PLoS Pathogens

Volumn 8, Issue 4, 2012, Pages

  Vassena, Lia ^a,b   Miao, Huiyi ^a   Cimbro, Raffaello ^a   Malnati, Mauro S ^b   Cassina, Giulia ^b   Proschan, Michael A ^a   Hirsch, Vanessa M ^a   Lafont, Bernard A ^a   Morre, Michel ^c   Fauci, Anthony S ^a   Lusso, Paolo ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b Unit of Human Virology   (Italy)

^c Cytheris ^*  (France)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PROTEIN BCL 2; TRANSACTIVATOR PROTEIN; VIRUS DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; AREA UNDER THE CURVE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DISEASE COURSE; DRUG SAFETY; FOLLOW UP; IN VIVO STUDY; INTERFERON PRODUCTION; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; NONHUMAN; PROTEIN EXPRESSION; RHESUS MONKEY; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS LOAD; VIRUS REPLICATION; ACUTE DISEASE; ANIMAL; CD4 CD8 RATIO; CHRONIC DISEASE; DRUG EFFECT; DRUG SCREENING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MACACA MULATTA; METABOLISM; VIROLOGY;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA; MACACA MULATTA; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

ACUTE DISEASE; ANIMALS; CD4-CD8 RATIO; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; DRUG EVALUATION, PRECLINICAL; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKIN-7; MACACA MULATTA; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 84861208977     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002636     Document Type: Article

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