Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease

PLoS Neglected Tropical Diseases

Volumn 6, Issue 4, 2012, Pages

  Guedes, Paulo Marcos Matta ^a,b   Gutierrez, Fredy Roberto Salazar ^b,c   Silva, Grace Kelly ^b   Dellalibera Joviliano, Renata ^b   Rodrigues, Gerson Jhonatan ^b   Bendhack, Lusiane Maria ^b   Rassi, Anis ^d   Schmidt, André ^b   Maciel, Benedito Carlos ^b   Marin Neto, José Antonio ^b   Silva, João Santana ^b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c CENTRO DE INVESTIGACIONES   (Colombia)

^d Anis Rassi Hospital   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BENZNIDAZOLE; CD103 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 17; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; CD4 ANTIGEN; CYTOKINE; IL2RA PROTEIN, HUMAN; INTERLEUKIN 2 RECEPTOR ALPHA;

ADULT; AGED; ARTICLE; CARDIOMYOPATHY; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL ACTIVITY; CELL PROLIFERATION; CHAGAS DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; HUMAN CELL; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; REGULATORY T LYMPHOCYTE; TH1 TH2 BALANCE; TH17 CELL; TRYPANOSOMA CRUZI; CELL CULTURE; CHEMISTRY; IMMUNOLOGY; IMMUNOPHENOTYPING; MIDDLE AGED; MONONUCLEAR CELL; PATHOLOGY; SECRETION;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD4; CELLS, CULTURED; CHAGAS CARDIOMYOPATHY; CYTOKINES; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 84861208495     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001630     Document Type: Article

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