Intercellular adhesion molecule 1 deficiency leads to impaired recruitment of T lymphocytes and enhanced host susceptibility to infection with Trypanosoma cruzi

Journal of Immunology

Volumn 173, Issue 1, 2004, Pages 463-470

  Michailowsky, Vladimir ^a   Celes, Mara R N ^b   Marino, Ana P ^a   Silva, Andréa A ^a   Vieira, Leda Q ^c   Rossi, Marcos A ^b   Gazzinelli, Ricardo T ^a,c   Lannes Vieira, Joseli ^a   Silva, João S ^b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN G2A; INTERCELLULAR ADHESION MOLECULE 1; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HEART; HOST RESISTANCE; IMMUNE DEFICIENCY; INFECTION SENSITIVITY; INFLAMMATORY CELL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PARASITISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TH1 CELL; TRYPANOSOMA CRUZI; TRYPANOSOMIASIS; VASCULAR ENDOTHELIUM; WILD TYPE;

EID: 2942704035     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.1.463     Document Type: Article

References (46)

1. Parada, H., H. A. Carrasco, N. Añez, C. Fuenmayor, and I. Inglessis. 1997. Cardiac involvement is a constant finding in acute Chagas' disease: a clinical parasitological and histopathological study. Int. J. Cardiol. 60:49.
2. Rossi, M. A., and R. B. Bestetti. 1995. The challenge of chagasic cardiomyopathy: the pathologic roles of anatomic abnormalities, autoimmune mechanism and microvascular changes, and therapeutic implications. Cardiology 86:1.
3. Dias, J. C. P. 1989. The indeterminate form of human chronic Chagas' disease: a clinical epidemiological review. Rev. Soc. Bras. Med. Trop. 22:147.
4. Teixeira, M. M., R. T. Gazzinelli, and J. S. Silva. 2002. Chemokines, inflammation and Trypanosoma cruzi. Trends Parasitol. 4:883.
5. + T cell-mediated myocarditis: chemokine receptors and adhesion molecules as potential therapeutic targets to control chronic inflammation? Mem. Inst. Oswaldo Cruz 98:299.
6. Higuchi, M. L., T. Brito, M. M. Reis, A. Barbosa, G. Bellotti, A. C. Pereira-Barreto, and F. Pileggi. 1997. Correlation between Trypanosoma cruzi parasitism and myocardial inflammatory infiltrate in human chronic chagasic myocarditis: light microscopy and immunohistochemical findings. Cardiovasc. Pathol. 2:101.
7. Añez, N., H. Carrasco, H. Parada, G. Crisante, A. Rojas, C. Fuenmayor, N. Gonzales, G. Percoco, R. Borges, P. Guevara, and J. L. Ramirez. 1999. Myocardial parasite persistence in chronic chagasic patients. Am. J. Trop. Med. Hyg. 60:726.
8. Vago, A. R., A. M. Macedo, S. J. Adad, D. D. Reis, and R. Correa-Oliveira. 1996. PCR detection of Trypanosoma cruzi DNA in oesophageal tissues of patients with chronic digestive Chagas' disease. Lancet 28:891.
9. Michailowsky, V., N. M. Silva, C. D. Rocha, L. Q. Vieira, J. Lannes-Vieira, and R. T. Gazzinelli. 2001. Pivotal role of interleukin-12 and interferon-γ axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection. Am. J. Pathol. 159:1723.
10. Tarleton, R. L., L. Zhang, and M. O. Downs. 1997. "Autoimmune rejection" of neonatal heart transplants in experimental Chagas disease is a parasite-specific response to infected host tissue. Proc. Natl. Acad. Sci. USA 94:3932.
11. Higuchi, M. L., P. S. Gutierrez, V. D. Aiello, S. Palomino, E. Bocchi, J. Kalil, G. Bellotti, and F. Pileggi, 1993. Immunohistochemical characterization of infiltrating cells in human chronic chagasic myocarditis: comparison with myocardial rejection process, Virchows Arch. A Pathol. Anat. 423:157.
12. + T cells with the presence of Trypanosoma cruzi antigens. Clin. Immunol. Immunopathol. 56:485.
13. Talvani, A., C. S. Ribeiro, J. C. Aliberti, V. Michailowsky, P. V. Santos, S. M. Murta, A. J. Romanha, I. C. Almeida, J. Farber, J. Lannes-Vieira, et al. 2000. Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: tissue parasitism and endogenous IFN-γ as important determinants of chemokines mRNA expression during infection with Trypanosoma cruzi. Microbes Infect. 2:851.
14. high activation phenotype and expression of IFN-γ-inducible adhesion and chemoattractant molecules. Microbes Infect. 3:971.
15. Russo, M., N. Starobinas, P. Minoprio, A. Coutinho, and M. Hontebeyrie-Joskowicz. 1988. Parasitic load increases and myocardial inflammation decreases in Trypanosoma cruzi-infected mice after inactivation of helper T cells. Ann. Inst. Pasteur Immunol. 139:225.
16. Tarleton, R. L., J. Sun, L. Zhang, and M. Postan. 1994. Depletion of T-cell subpopulations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease. Infect. Immun. 62:1820.
17. 2microglobulin-deficient mice to Trypanosoma cruzi infection. Nature 26:338.
18. Cardillo, F., J. C. Voltarelli, S. G. Reed, and J. S. Silva. 1996. Regulation of Trypanosoma cruzi infection in mice by γ interferon and interleukin 10: role of NK cells. Infect. Immun. 64:128.
19. Abrahamsohn, I. A., and R. L. Coffman. 1996. Trypanosoma cruzi: IL-10, TNF, IFN-γ and IL-12 regulate innate and acquired immunity to infection. Exp. Parasitol. 84:231.
20. Castaños-Velez, E., S. Maerlan, L. M. Osorio, F. Åberg, P. Biberfeld, A. Orn, and M. E. Rottenberg. 1998. Trypanosoma cruzi Infection in tumor necrosis factor receptor p55-deficient mice. Infect. Immun. 66:2960.
21. Silva, J. S., G. N. Vespa, M. A. Cardoso, J. C. Aliberti, and F. Q. Cunha. 1995. Tumor necrosis factor a mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected γ interferon-activated macrophages. Infect. Immun. 63:4862.
22. Gazzinelli, R. T., I. P. Oswald, S. Hieny, S. James, and A. Sher. 1992. The microbicidal activity of interferon-γ treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-α. Eur. J. Immunol. 22:2501.
23. Vespa, G. N. R., F. Q. Cunha, and J. S. Silva. 1994. Nitric oxide is involved in the control of Trypanosoma cruzi induced parasitemia and directly kills parasite in vitro. Infect. Immun. 62:5177.
24. Holscher, C., G. Kohler, U. Muller, H. Mossmann, G. A. Schaub, and F. Brombacher. 1998. Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in γ interferon receptor or inducible nitric oxide synthase. Infect. Immun. 66:1208.
25. Aliberti, J. C., J. T. Souto, A. P. Marino, J. Lannes-Vieira, M. M. Teixeira, J. Farber, R. T. Gazzinelli, and J. S. Silva. 2001. Modulation of chemokine production and inflammatory responses in interferon-γ- and tumor necrosis factor-R1-deficient mice during Trypanosoma cruzi infection. Am. J. Pathol. 158:1433.
26. Zhang, L., and R. L. Tarleton. 1996. Persistent production of inflammatory and anti-inflammatory cytokines and associated MHC and adhesion molecule expression at the site of infection and disease in experimental Trypanosoma cruzi infections. Exp. Parasitol. 84:203.
27. Marino, A. P., M. I. P. Azevedo, and J. Lannes-Vieira. 2003. Differential expression of adhesion molecules shaping the T-cell subset prevalence in autoimmune and Trypanosoma cruzi-elicited myocarditis. Mem. Inst. Oswaldo Cruz 98:945.
28. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301.
29. Camacho, S. A., W. R. Heath, F. R. Carbone, N. Sarvetnick, A. LeBon, L. Karlsson, P. A. Peterson, and S. R. Webb. 2001. A key role for ICAM-1 in generating effector cells mediating inflammatory responses. Nat. Immunol. 2:523.
30. Laucella, S., R. Salcedo, E. Castanos-Velez, A. Riarte, E. H. De Titto, M. Patarroyo, A. Orn, and M. E. Rottenberg. 1996. Increased expression and secretion of ICAM-1 during experimental infection with Trypanosoma cruzi. Parasite Immunol. 18:227.
31. Schmidt, H. H. W., P. Wilke, and E. Bohme. 1989. Enzymatic formation of nitrogen oxides from L-arginine in bovine brain cytosol. Biochem. Biophys. Res. Commun, 165:284.
32. Green, L. C., S. R. Tannenbaum, and P. Goldman. 1981. Nitrate biosynthesis in germfree and conventional rat. Science 212:56.
33. + T-cell-mediated Trypanosoma cruzi-elicited meningoencephalitis. J. Neuroimmunol. 142:17.
34. Taub, D. D., A. R. Lloyd, K. Conlon, J. M. Wang, J. R. Ortaldo, A. Harada, K. Matsushima, D. J. Kelvin, and J. J. Oppenheim. 1993. Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J. Exp. Med. 17:1809.
35. Proudfoot, A. E. 2002. Chemokine receptors: multifaceted therapeutic targets. Nat. Rev. Immunol. 2:106.
36. Aliberti, J. C., F. S. Machado, J. T. Souto, A. P. Campanelli, M. M. Teixeira, R. T. Gazzinelli, and J. S. Silva. 1999. β-Chemokines enhance parasite uptake and promote nitric oxide-dependent microbiostatic activity in murine inflammatory macrophages infected with Trypanosoma cruzi. Infect. Immun. 67:4819.
37. Machado, F. S., G. A. Martins, J. C. Aliberti, F. L. Mestriner, F. Q. Cunha, and J. S. Silva. 2000. Trypanosoma cruzi-infected cardiomyocytes produce chemokines and cytokines that trigger potent nitric oxide-dependent trypanocidal activity. Circulation 102:3003.
38. Benvenuti, L. A., M. L. Higuchi, and M. M. Reis. 2000. Upregulation of adhesion molecules and class I HLA in the myocardium of chronic chagasic cardiomyopathy and heart allograft rejection, but not in dilated cardiomyopathy. Cardiovasc. Pathol. 9:111.
39. Zhang, Q. W., D. D. Kish, and R. L. Fairchild. 2003. Absence of allograft ICAM-1 attenuates alloantigen-specific T cell priming, but not primed T cell trafficking into the graft, to mediate acute rejecfion. J. Immunol. 170:5530.
40. Cofano, F., P. M. Comoglio, S. Landolfo, and G. Tarone. 1984. Mouse immune interferon enhances fibronectin production of elicited macrophages. J. Immunol. 133:3102.
41. Higuchi, M. L., S. Fukasawa, T. De Brito, L. C. Parzianello, G. Bellotti, and J. A. Ramires. 1999. Different microcirculatory and interstitial matrix patterns in idiopathic dilated cardiomyopathy and Chagas' disease: a three dimensional confocal microscopy study. Heart 82:279.
42. Wirth, J. J., and F. Kierszenbaum. 1984. Fibronectin enhances macrophage association with invasive forms of Trypanosoma cruzi. J. Immunol. 133:460.
43. Suzuki, J., M. Isobe, A. Izawa, W. Takahashi, S. Yamazaki, Y. Okubo, J. Amano, and M. Sekiguchi. 1999. Differential Th1 and Th2 cell regulation of murine cardiac allograft acceptance by blocking cell adhesion of ICAM-1/LFA-1 and VCAM-1/VLA-4. Transplant. Immunol. 7:65.
44. Murray, H. 2000. Mononuclear cell recruitment, granuloma assembly, and response to treatment in experimental visceral leishimaniasis: Intracellular adhesion molecule-I dependent and independent regulation. Infect. Immun. 68:6294.
45. Davis, S. L., E. P. Hawkins, E. O. Mason, C. W. Smith, and S. L. Kaplan. 1996. Host defenses against disseminated candidiasis are impaired in intracellular adhesion molecule 1-deficient mice. J. Infect. Dis. 174:435.
46. Steeber, D. A., M. L. Tang, N. E. Green, Q. X. Zhang, J. E. Sloane, and T. F. Tedder. 1999. Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways. J. Immunol. 163:2176.