New circulin macrocyclic polypeptides from Chassalia parvifolia

Journal of Natural Products

Volumn 63, Issue 2, 2000, Pages 176-178

  Gustafson, Kirk R ^a   Walton, Linda K ^a   Sowder II, Raymond C ^b   Johnson, Donald G ^b   Pannell, Lewis K ^c   Cardellina II, John H ^a   Boyd, Michael R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCULIN C; CIRCULIN D; CIRCULIN E; CIRCULIN F; POLYPEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CYTOPATHOGENIC EFFECT; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; SEQUENCE HOMOLOGY; TREE;

ALKYLATION; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ANTI-HIV AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOTIDES; CYSTEINE; HIV-1; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PLANT STEMS; PLANTS, MEDICINAL; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; TASMANIA;

CHASSALIA; CHASSALIA PARVIFOLIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0034002318     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np990432r     Document Type: Article

References (20)

1. 20
2. Gustafson, K. R.; Sowder, R. C., II; Henderson, L. E.; Parsons, I. C.; Kashman Y.; Cardellina, J. H., II; McMahon, J. B.; Buckheit, R. W., Jr.; Pannell, L. K.; Boyd, M. R. J. Am. Chem. Soc. 1994, 113, 9337-9338.
3. Witherup, K. M.; Bogusky, M. J.; Anderson, P. S.; Ramjit, H.; Ransom, R. W.; Wood, T.; Sardana, M. J. Nat. Prod. 1994, 57, 1619-1625.
4. Saether, O.; Craik, D. J.; Campbell, I. D.; Sletten, K; Juul, J.; Norman, D. G. Biochemistry 1995, 34, 414-7-4158.
5. Goransson, U.; Luijendijk, T.; Johansson, S.; Bohlin, L.; Claeson, P. J. Nat. Prod. 1999, 62, 283-286.
6. Claeson, P.; Goransson, U.; Johansson, S.; Luijendijk, T.; Bohlin, L. J. Nat. Prod. 1998, 61, 77-81.
7. Schopke, I.; Hasan Ahha, M. I.; Kraft, R.; Otto, A.; Hiller, K. Sci. Pharm. 1993, 61, 145-153.
8. Hallock, Y. F.; Sowder, R. C., II; Pannell, L. K.; Hughes, C. B.; Johnson, D. G.; Gulakowski, R. J.; Cardellina, J. H., II; Boyd, M. R. J. Org. Chem. (in press).
9. Derua, R.; Gustafson, K. R.; Pannell, L. K. Biochem. Biophys. Res. Commun. 1996, 228, 632-638.
10. Daly, N. L.; Koltay, A.; Gustafson, K. R.; Boyd, M. R.; Casas-Finet, J. R.; Craik, D. J. J. Mol. Biol. 1999, 285, 333-345.
11. Isaacs, N. W. Curr. Opin. Struct. Biol. 1995, 5, 391-395.
12. Pallaghy, P. K.; Nielsen, K. J.; Craik, D. J.; Norton, R. S. Protein Sci. 1994, 3, 1833-1839.
13. Boyd, M. R. In AIDS Etiology, Diagnosis, Treatment and Prevention; De Vita, V. T., Jr., Hellman, S., Rosenberg, S. A., Eds.; Lippincott: Philadelphia, 1988; pp 305-319.
14. Mass values quoted are average molecular weights.
15. Addition of each pyridylethyl group results in an increase of approximately 106.1 Da in the molecular weight of a PEC derivative, relative to the molecular weight of a native peptide in which all cysteines are disulfide linked.
16. Gulakowski, R. J.; McMahon, J. B.; Staley, P. G.; Moran, R. A.; Boyd, M. R. J. Virol Methods 1991, 33, 87-100.
17. Currens, M. J.; Gulakowski, R. J.; Mariner, J. M.; Moran, R. A.; Buckheit, R. W., Jr.; Gustafson, K. R.; McMahon, J. B.; Boyd, M. R. J. Pharmacol. Exp. Ther. 1996, 279, 645-651.
18. Buckheit, R. W., Jr.; Fliakas-Boltz, V.; Decker, W. D.; Robertson, J. L.; Pyle, C. A.; White, E. L.; Bowden, B. J.; McMahon, J. B.; Boyd, M. R.; Bader, J. P.; Nickell, D. G.; Barth, H.; Antonucci, T. K. Antiviral Res. 1994, 25, 43-56.
19. Grode, S. H.; James, T. R.; Cardellina, J. H., II; Onan, K. D. J. Org. Chem. 1983, 48, 5203-5207.
20. Rashid, M. A.; Gustafson, K. R.; Boyd, M. R. J. Nat. Prod. (in press).