메뉴 건너뛰기




Volumn 38, Issue 5, 2012, Pages 387-396

Docetaxel combined with targeted therapies in metastatic breast cancer

Author keywords

Bevacizumab; Breast cancer; Docetaxel; Metastatic; Targeted therapy; Trastuzumab

Indexed keywords

AXITINIB; BEVACIZUMAB; CAPECITABINE; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; ERLOTINIB; EVEROLIMUS; FLUOROURACIL; GEMCITABINE; IMATINIB; LAPATINIB; METHOTREXATE; MITOMYCIN; NAVELBINE; NERATINIB; PACLITAXEL; PERTUZUMAB; PLACEBO; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; SORAFENIB; SUNITINIB; TANESPIMYCIN; TAXANE DERIVATIVE; TRASTUZUMAB; TRASTUZUMAB EMTANSINE; VINBLASTINE;

EID: 84861196060     PISSN: 03057372     EISSN: 15321967     Source Type: Journal    
DOI: 10.1016/j.ctrv.2011.08.001     Document Type: Review
Times cited : (16)

References (94)
  • 2
    • 33846436108 scopus 로고    scopus 로고
    • Cancer statistics, trends, and multiple primary cancer analyses from the Surveillance, Epidemiology, and End Results (SEER) Program
    • Hayat M.J., Howlader N., Reichman M.E., Edwards B.K. Cancer statistics, trends, and multiple primary cancer analyses from the Surveillance, Epidemiology, and End Results (SEER) Program. Oncologist 2007, 12:20-37.
    • (2007) Oncologist , vol.12 , pp. 20-37
    • Hayat, M.J.1    Howlader, N.2    Reichman, M.E.3    Edwards, B.K.4
  • 4
    • 0037132372 scopus 로고    scopus 로고
    • Docetaxel versus 5-fluorouracil plus vinorelbine in metastatic breast cancer after anthracycline therapy failure
    • Bonneterre J., Roche H., Monnier A., et al. Docetaxel versus 5-fluorouracil plus vinorelbine in metastatic breast cancer after anthracycline therapy failure. Br J Cancer 2002, 87:1210-1215.
    • (2002) Br J Cancer , vol.87 , pp. 1210-1215
    • Bonneterre, J.1    Roche, H.2    Monnier, A.3
  • 5
    • 0032787785 scopus 로고    scopus 로고
    • Prospective randomized trial of docetaxel versus doxorubicin in patients with metastatic breast cancer
    • Chan S., Friedrichs K., Noel D., et al. Prospective randomized trial of docetaxel versus doxorubicin in patients with metastatic breast cancer. J Clin Oncol 1999, 17:2341-2354.
    • (1999) J Clin Oncol , vol.17 , pp. 2341-2354
    • Chan, S.1    Friedrichs, K.2    Noel, D.3
  • 6
    • 24944507764 scopus 로고    scopus 로고
    • Randomized phase III study of docetaxel compared with paclitaxel in metastatic breast cancer
    • Jones S.E., Erban J., Overmoyer B., et al. Randomized phase III study of docetaxel compared with paclitaxel in metastatic breast cancer. J Clin Oncol 2005, 23:5542-5551.
    • (2005) J Clin Oncol , vol.23 , pp. 5542-5551
    • Jones, S.E.1    Erban, J.2    Overmoyer, B.3
  • 7
    • 0032949449 scopus 로고    scopus 로고
    • Prospective randomized trial of docetaxel versus mitomycin plus vinblastine in patients with metastatic breast cancer progressing despite previous anthracycline containing chemotherapy. 304 Study Group
    • Nabholtz J.M., Senn H.J., Bezwoda W.R., et al. Prospective randomized trial of docetaxel versus mitomycin plus vinblastine in patients with metastatic breast cancer progressing despite previous anthracycline containing chemotherapy. 304 Study Group. J Clin Oncol 1999, 17:1413-1424.
    • (1999) J Clin Oncol , vol.17 , pp. 1413-1424
    • Nabholtz, J.M.1    Senn, H.J.2    Bezwoda, W.R.3
  • 8
    • 0037096755 scopus 로고    scopus 로고
    • Superior survival with capecitabine plus docetaxel combination therapy in anthracycline pretreated patients with advanced breast cancer: phase III trial results
    • O'Shaughnessy J., Miles D., Vukelja S., et al. Superior survival with capecitabine plus docetaxel combination therapy in anthracycline pretreated patients with advanced breast cancer: phase III trial results. J Clin Oncol 2002, 20:2812-2823.
    • (2002) J Clin Oncol , vol.20 , pp. 2812-2823
    • O'Shaughnessy, J.1    Miles, D.2    Vukelja, S.3
  • 9
    • 17344390083 scopus 로고    scopus 로고
    • Docetaxel compared with sequential methotrexate and 5-fluorouracil in patients with advanced breast cancer after anthracycline failure: a randomised phase III study with crossover on progression by the Scandinavian Breast Group
    • Sjöstrom J., Blomqvist C., Mouridsen H., et al. Docetaxel compared with sequential methotrexate and 5-fluorouracil in patients with advanced breast cancer after anthracycline failure: a randomised phase III study with crossover on progression by the Scandinavian Breast Group. Eur J Cancer 1999, 35:1194-1201.
    • (1999) Eur J Cancer , vol.35 , pp. 1194-1201
    • Sjöstrom, J.1    Blomqvist, C.2    Mouridsen, H.3
  • 10
    • 0037445247 scopus 로고    scopus 로고
    • Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: results of a randomized, multicenter, phase III trial
    • Nabholtz J.M., Falkson C., Campos D., et al. Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: results of a randomized, multicenter, phase III trial. J Clin Oncol 2003, 21:968-975.
    • (2003) J Clin Oncol , vol.21 , pp. 968-975
    • Nabholtz, J.M.1    Falkson, C.2    Campos, D.3
  • 11
    • 27244438750 scopus 로고    scopus 로고
    • Phase II to III study comparing doxorubicin and docetaxel with fluorouracil, doxorubicin, and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: results of a Dutch Community Setting Trial for the Clinical Trial Group of the Comprehensive Cancer Centre
    • Bontenbal M., Creemers G.J., Braun H.J., et al. Phase II to III study comparing doxorubicin and docetaxel with fluorouracil, doxorubicin, and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: results of a Dutch Community Setting Trial for the Clinical Trial Group of the Comprehensive Cancer Centre. J Clin Oncol 2005, 23:7081-7088.
    • (2005) J Clin Oncol , vol.23 , pp. 7081-7088
    • Bontenbal, M.1    Creemers, G.J.2    Braun, H.J.3
  • 12
    • 26844559765 scopus 로고    scopus 로고
    • Trastuzumab in the treatment of breast cancer
    • Hortobagyi G. Trastuzumab in the treatment of breast cancer. N Engl J Med 2005, 353:1734-1736.
    • (2005) N Engl J Med , vol.353 , pp. 1734-1736
    • Hortobagyi, G.1
  • 13
    • 37049183697 scopus 로고
    • Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon D.J., Clark G.M., Wong S.G., et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987, 235:177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 14
    • 0032735292 scopus 로고    scopus 로고
    • Biologic approaches to managing advanced breast cancer
    • Slamon D. Biologic approaches to managing advanced breast cancer. Cancer Control 1999, 6(Suppl. 2):7-11.
    • (1999) Cancer Control , vol.6 , Issue.SUPPL. 2 , pp. 7-11
    • Slamon, D.1
  • 15
    • 0020933452 scopus 로고
    • Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors
    • Sato J.D., Kawamoto T., Le A.D., et al. Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors. Mol Biol Med 1983, 1:511-529.
    • (1983) Mol Biol Med , vol.1 , pp. 511-529
    • Sato, J.D.1    Kawamoto, T.2    Le, A.D.3
  • 16
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • Bergers G., Benjamin L.E. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003, 3:401-410.
    • (2003) Nat Rev Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 17
    • 0036984738 scopus 로고    scopus 로고
    • Tumor angiogenesis and accessibility: role of vascular endothelial growth factor
    • Jain R.K. Tumor angiogenesis and accessibility: role of vascular endothelial growth factor. Semin Oncol 2002, 29:3-9.
    • (2002) Semin Oncol , vol.29 , pp. 3-9
    • Jain, R.K.1
  • 18
    • 0017842951 scopus 로고
    • Angiogenesis as a marker of preneoplastic lesions of the human breast
    • Brem S.S., Jensen H.M., Gullino P.M. Angiogenesis as a marker of preneoplastic lesions of the human breast. Cancer 1978, 41:239-244.
    • (1978) Cancer , vol.41 , pp. 239-244
    • Brem, S.S.1    Jensen, H.M.2    Gullino, P.M.3
  • 19
    • 0019986657 scopus 로고
    • Angiogenesis induced "normal" human breast tissue: a probable marker for precancer
    • Jensen H.M., Chen I., DeVault M.R., Lewis A.E. Angiogenesis induced "normal" human breast tissue: a probable marker for precancer. Science 1982, 218:293-295.
    • (1982) Science , vol.218 , pp. 293-295
    • Jensen, H.M.1    Chen, I.2    DeVault, M.R.3    Lewis, A.E.4
  • 20
    • 0031807642 scopus 로고    scopus 로고
    • Angiogenic potential of malignant and non-malignant human breast tissues in an in vivo angiogenesis model
    • Lichtenbeld H.C., Barendsz-Janson A.F., van Essen H., et al. Angiogenic potential of malignant and non-malignant human breast tissues in an in vivo angiogenesis model. Int J Cancer 1998, 77:455-459.
    • (1998) Int J Cancer , vol.77 , pp. 455-459
    • Lichtenbeld, H.C.1    Barendsz-Janson, A.F.2    van Essen, H.3
  • 21
    • 0027848781 scopus 로고
    • Relationship of endothelial cell proliferation to tumor vascularity in human breast cancer
    • Fox S.B., Gatter K.C., Bicknell R., et al. Relationship of endothelial cell proliferation to tumor vascularity in human breast cancer. Cancer Res 1993, 53:4161-4163.
    • (1993) Cancer Res , vol.53 , pp. 4161-4163
    • Fox, S.B.1    Gatter, K.C.2    Bicknell, R.3
  • 22
    • 0033962101 scopus 로고    scopus 로고
    • Relationship of vascular maturation in breast cancer blood vessels to vascular density and metastasis, assessed by expression of a novel basement membrane component, LH39
    • Kakolyris S., Fox S.B., Koukourakis M., et al. Relationship of vascular maturation in breast cancer blood vessels to vascular density and metastasis, assessed by expression of a novel basement membrane component, LH39. Br J Cancer 2000, 82:844-851.
    • (2000) Br J Cancer , vol.82 , pp. 844-851
    • Kakolyris, S.1    Fox, S.B.2    Koukourakis, M.3
  • 23
    • 33845529437 scopus 로고    scopus 로고
    • Pro-angiogenic cytokines and their role in tumor angiogenesis
    • Neufeld G., Kessler O. Pro-angiogenic cytokines and their role in tumor angiogenesis. Cancer Metastasis Rev 2006, 25:373-385.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 373-385
    • Neufeld, G.1    Kessler, O.2
  • 24
    • 33947370773 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) signalling in tumor progression
    • Roskoski R. Vascular endothelial growth factor (VEGF) signalling in tumor progression. Crit Rev Oncol Hematol 2007, 62:179-213.
    • (2007) Crit Rev Oncol Hematol , vol.62 , pp. 179-213
    • Roskoski, R.1
  • 25
    • 77951296573 scopus 로고    scopus 로고
    • Phase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer
    • Barrios C.H., Liu M.C., Lee S.C., et al. Phase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer. Breast Cancer Res Treat 2010, 121:121-131.
    • (2010) Breast Cancer Res Treat , vol.121 , pp. 121-131
    • Barrios, C.H.1    Liu, M.C.2    Lee, S.C.3
  • 26
    • 77955894152 scopus 로고    scopus 로고
    • Phase III trial of sunitinib (SU) in combination with capecitabine (C) versus C in previously treated advanced breast cancer (ABC)
    • abstract LBA1011.
    • Crown J, Dieras V, Staroslawska E, et al. Phase III trial of sunitinib (SU) in combination with capecitabine (C) versus C in previously treated advanced breast cancer (ABC). J Clin Oncol 2010;28(Suppl. 18s):abstract LBA1011.
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL. 18S
    • Crown, J.1    Dieras, V.2    Staroslawska, E.3
  • 27
    • 12144289561 scopus 로고    scopus 로고
    • A phase II study of three-weekly docetaxel and weekly trastuzumab in HER2-overexpressing advanced breast cancer
    • Montemurro F., Choa G., Faggiuolo R., et al. A phase II study of three-weekly docetaxel and weekly trastuzumab in HER2-overexpressing advanced breast cancer. Oncology 2004, 66:38-45.
    • (2004) Oncology , vol.66 , pp. 38-45
    • Montemurro, F.1    Choa, G.2    Faggiuolo, R.3
  • 28
    • 1842614241 scopus 로고    scopus 로고
    • Docetaxel combined with trastuzumab is an active regimen in HER-2 3+ overexpressing and fluorescent in situ hybridization-positive metastatic breast cancer: a multi-institutional phase II trial
    • Tedesco K.L., Thor A.D., Johnson D.H., et al. Docetaxel combined with trastuzumab is an active regimen in HER-2 3+ overexpressing and fluorescent in situ hybridization-positive metastatic breast cancer: a multi-institutional phase II trial. J Clin Oncol 2004, 22:1071-1077.
    • (2004) J Clin Oncol , vol.22 , pp. 1071-1077
    • Tedesco, K.L.1    Thor, A.D.2    Johnson, D.H.3
  • 29
    • 22344446208 scopus 로고    scopus 로고
    • Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group
    • Marty M., Cognetti F., Maraninchi D., et al. Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group. J Clin Oncol 2005, 23:4265-4274.
    • (2005) J Clin Oncol , vol.23 , pp. 4265-4274
    • Marty, M.1    Cognetti, F.2    Maraninchi, D.3
  • 30
    • 80051766451 scopus 로고    scopus 로고
    • Randomized phase II study comparing efficacy and safety of combination therapy trastuzumab and docetaxel vs. sequential therapy of trastuzumab followed by docetaxel alone at progression as first-line chemotherapy in patients with HER2+ metastatic breast cancer: HERTAX trial
    • Hamberg P., Bos M.M., Braun H.J., et al. Randomized phase II study comparing efficacy and safety of combination therapy trastuzumab and docetaxel vs. sequential therapy of trastuzumab followed by docetaxel alone at progression as first-line chemotherapy in patients with HER2+ metastatic breast cancer: HERTAX trial. Clin Breast Cancer 2011, 11:103-113.
    • (2011) Clin Breast Cancer , vol.11 , pp. 103-113
    • Hamberg, P.1    Bos, M.M.2    Braun, H.J.3
  • 31
    • 33744812137 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab in combination with weekly docetaxel in metastatic breast cancer patients
    • Ramaswamy B., Elias A.D., Kelbick N.T., et al. Phase II trial of bevacizumab in combination with weekly docetaxel in metastatic breast cancer patients. Clin Cancer Res 2006, 12:3124-3129.
    • (2006) Clin Cancer Res , vol.12 , pp. 3124-3129
    • Ramaswamy, B.1    Elias, A.D.2    Kelbick, N.T.3
  • 32
    • 77955608564 scopus 로고    scopus 로고
    • A phase II trial of docetaxel with bevacizumab as first-line therapy for HER2-negative metastatic breast cancer (TORI B01)
    • Hurvitz S.A., Allen H.J., Moroose R.L., et al. A phase II trial of docetaxel with bevacizumab as first-line therapy for HER2-negative metastatic breast cancer (TORI B01). Clin Breast Cancer 2010, 10:307-312.
    • (2010) Clin Breast Cancer , vol.10 , pp. 307-312
    • Hurvitz, S.A.1    Allen, H.J.2    Moroose, R.L.3
  • 34
    • 77950544279 scopus 로고    scopus 로고
    • Sequential administration of sunitinib (SU) and docetaxel (D) in women with advanced breast cancer (ABC): an exploratory evaluation
    • abstract 14534.
    • Mariani G, Cardoso F, Besse-Hammer T, et al. Sequential administration of sunitinib (SU) and docetaxel (D) in women with advanced breast cancer (ABC): an exploratory evaluation. J Clin Oncol 2008;26(Suppl.):abstract 14534.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Mariani, G.1    Cardoso, F.2    Besse-Hammer, T.3
  • 35
    • 77956187531 scopus 로고    scopus 로고
    • Multicenter phase II randomized trial evaluating antiangiogenic therapy with sunitinib as consolidation after objective response to taxane chemotherapy in women with HER2-negative metastatic breast cancer
    • Wildiers C., Fontaine C., Vuylsteke P., et al. Multicenter phase II randomized trial evaluating antiangiogenic therapy with sunitinib as consolidation after objective response to taxane chemotherapy in women with HER2-negative metastatic breast cancer. Breast Cancer Res Treat 2010, 123:463-469.
    • (2010) Breast Cancer Res Treat , vol.123 , pp. 463-469
    • Wildiers, C.1    Fontaine, C.2    Vuylsteke, P.3
  • 36
    • 77955911251 scopus 로고    scopus 로고
    • Sunitinib (SU) in combination with docetaxel (D) versus D alone for the first-line treatment of advanced breast cancer (ABC)
    • abstract LBA1010.
    • Bergh J, Greil R, Voytko N, et al. Sunitinib (SU) in combination with docetaxel (D) versus D alone for the first-line treatment of advanced breast cancer (ABC). J Clin Oncol 2010;28(Suppl. 18s):abstract LBA1010.
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL. 18S
    • Bergh, J.1    Greil, R.2    Voytko, N.3
  • 37
    • 73349116185 scopus 로고    scopus 로고
    • Phase II trial of docetaxel plus imatinib mesylate in the treatment of patients with metastatic breast cancer
    • Yardley D.A., Burris H.A., Markus T., et al. Phase II trial of docetaxel plus imatinib mesylate in the treatment of patients with metastatic breast cancer. Clin Breast Cancer 2009, 9:237-242.
    • (2009) Clin Breast Cancer , vol.9 , pp. 237-242
    • Yardley, D.A.1    Burris, H.A.2    Markus, T.3
  • 38
    • 77949893849 scopus 로고    scopus 로고
    • Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer
    • Wardley A.M., Pivot X., Morales-Vasquez F., et al. Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer. J Clin Oncol 2010, 28:976-983.
    • (2010) J Clin Oncol , vol.28 , pp. 976-983
    • Wardley, A.M.1    Pivot, X.2    Morales-Vasquez, F.3
  • 39
    • 79951982754 scopus 로고    scopus 로고
    • Multicenter phase III randomized trial comparing docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab as first-line chemotherapy for patients with HER2-gene-amplified metastatic breast cancer (BCIRG 007 study): two highly active therapeutic regimens
    • Valero V., Forbes J., Pegram M.D., et al. Multicenter phase III randomized trial comparing docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab as first-line chemotherapy for patients with HER2-gene-amplified metastatic breast cancer (BCIRG 007 study): two highly active therapeutic regimens. J Clin Oncol 2011, 29:149-156.
    • (2011) J Clin Oncol , vol.29 , pp. 149-156
    • Valero, V.1    Forbes, J.2    Pegram, M.D.3
  • 40
    • 77954700380 scopus 로고    scopus 로고
    • Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
    • Miles D.W., Chan A., Dirix L.Y., et al. Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. J Clin Oncol 2010, 28:3239-3247.
    • (2010) J Clin Oncol , vol.28 , pp. 3239-3247
    • Miles, D.W.1    Chan, A.2    Dirix, L.Y.3
  • 41
    • 79953874259 scopus 로고    scopus 로고
    • RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer
    • Robert N.J., Dieras V., Glaspy J., et al. RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer. J Clin Oncol 2011, 29:1252-1260.
    • (2011) J Clin Oncol , vol.29 , pp. 1252-1260
    • Robert, N.J.1    Dieras, V.2    Glaspy, J.3
  • 42
    • 79952027747 scopus 로고    scopus 로고
    • First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: safety and efficacy in an open-label study in 2251 patients
    • Smith I.E., Pierga J.Y., Biganzoli L., et al. First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: safety and efficacy in an open-label study in 2251 patients. Ann Oncol 2011, 22:595-602.
    • (2011) Ann Oncol , vol.22 , pp. 595-602
    • Smith, I.E.1    Pierga, J.Y.2    Biganzoli, L.3
  • 54
  • 55
    • 0033118889 scopus 로고    scopus 로고
    • Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers
    • Pegram M., Hsu S., Lewis G., et al. Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers. Oncogene 1999, 18:2241-2251.
    • (1999) Oncogene , vol.18 , pp. 2241-2251
    • Pegram, M.1    Hsu, S.2    Lewis, G.3
  • 56
    • 2942659576 scopus 로고    scopus 로고
    • Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer
    • Pegram M.D., Konecny G.E., O'Callaghan C., et al. Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer. J Natl Cancer Inst 2004, 96:739-749.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 739-749
    • Pegram, M.D.1    Konecny, G.E.2    O'Callaghan, C.3
  • 57
    • 84872758982 scopus 로고    scopus 로고
    • Superior long-term survival benefits of trastuzumab plus docetaxel compared to docetaxel alone in patients with HER2-positive metastatic breast cancer: patients surviving more than 4years in the M77001 study
    • 14-17 December. San Antonio, Texas.
    • Marty M, Cognetti F, Maraninchi D, et al. Superior long-term survival benefits of trastuzumab plus docetaxel compared to docetaxel alone in patients with HER2-positive metastatic breast cancer: patients surviving more than 4years in the M77001 study. Abstract 2067 presented at 29th San Antonio Breast Cancer Symposium, 14-17 December 2006. San Antonio, Texas.
    • (2006) Abstract 2067 presented at 29th San Antonio Breast Cancer Symposium
    • Marty, M.1    Cognetti, F.2    Maraninchi, D.3
  • 58
    • 13444278498 scopus 로고    scopus 로고
    • Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies
    • Gerber H.P., Ferrara N. Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies. Cancer Res 2005, 65:671-680.
    • (2005) Cancer Res , vol.65 , pp. 671-680
    • Gerber, H.P.1    Ferrara, N.2
  • 59
    • 0035870297 scopus 로고    scopus 로고
    • The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors
    • Sweeney C.J., Miller K.D., Sissons S.E., et al. The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors. Cancer Res 2001, 61:3369-3372.
    • (2001) Cancer Res , vol.61 , pp. 3369-3372
    • Sweeney, C.J.1    Miller, K.D.2    Sissons, S.E.3
  • 60
    • 80054883209 scopus 로고    scopus 로고
    • Efficacy and safety of bevacizumab in combination with docetaxel for the first-line treatment of elderly patients with locally recurrent or metastatic breast cancer: results from AVADO
    • [EPub ahead of print].
    • Pivot X, Schneeweiss A, Verma S, et al. Efficacy and safety of bevacizumab in combination with docetaxel for the first-line treatment of elderly patients with locally recurrent or metastatic breast cancer: results from AVADO. Eur. J. Cancer; 2011 [EPub ahead of print].
    • (2011) Eur. J. Cancer
    • Pivot, X.1    Schneeweiss, A.2    Verma, S.3
  • 61
    • 74649083066 scopus 로고    scopus 로고
    • Tolerability and efficacy of first-line bevacizumab (B) plus chemotherapy (CT) in elderly patients with advanced breast cancer (aBC): subpopulation analysis of the MO19391 study
    • abstract 1032.
    • Biganzoli L, Cortes-Funes H, Thomssen C, et al. Tolerability and efficacy of first-line bevacizumab (B) plus chemotherapy (CT) in elderly patients with advanced breast cancer (aBC): subpopulation analysis of the MO19391 study. J Clin Oncol 2009;27(Suppl. 15):abstract 1032.
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL. 15
    • Biganzoli, L.1    Cortes-Funes, H.2    Thomssen, C.3
  • 62
    • 0005248386 scopus 로고    scopus 로고
    • Food and Drug Administration [homepage on the internet]
    • [accessed 28.07.11].
    • Food and Drug Administration [homepage on the internet]. 2011 [accessed 28.07.11]. http://www.fda.gov.
    • (2011)
  • 63
    • 84861193390 scopus 로고    scopus 로고
    • European Medicines Agency [homepage on the internet]
    • [accessed 28.07.11].
    • European Medicines Agency [homepage on the internet]. 2011 [accessed 28.07.11]. http://www.ema.europa.eu.
    • (2011)
  • 64
    • 0037068741 scopus 로고    scopus 로고
    • Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways
    • Xia W., Mullin R.J., Keith B.R., et al. Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways. Oncogene 2002, 21:6255-6263.
    • (2002) Oncogene , vol.21 , pp. 6255-6263
    • Xia, W.1    Mullin, R.J.2    Keith, B.R.3
  • 65
    • 0942268145 scopus 로고    scopus 로고
    • Effects of the EGFR/HER2 kinase inhibitor GW572016 on EGFR- and HER2-overexpressing breast cancer cell line proliferation, radiosensitization, and resistance
    • Zhou H., Kim Y.S., Peletier A., McCall W., Earp H.S., Sartor C.I. Effects of the EGFR/HER2 kinase inhibitor GW572016 on EGFR- and HER2-overexpressing breast cancer cell line proliferation, radiosensitization, and resistance. Int J Radiat Oncol Biol Phys 2004, 58:344-352.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 344-352
    • Zhou, H.1    Kim, Y.S.2    Peletier, A.3    McCall, W.4    Earp, H.S.5    Sartor, C.I.6
  • 66
    • 40849102700 scopus 로고    scopus 로고
    • Activity of lapatinib a novel HER2 and EGFR dual kinase inhibitor in human endometrial cancer cells
    • Konecny G.E., Venkatesan N., Yang G., et al. Activity of lapatinib a novel HER2 and EGFR dual kinase inhibitor in human endometrial cancer cells. Br J Cancer 2008, 98:1076-1084.
    • (2008) Br J Cancer , vol.98 , pp. 1076-1084
    • Konecny, G.E.1    Venkatesan, N.2    Yang, G.3
  • 67
    • 46449138403 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of lapatinib and docetaxel in patients with advanced cancer
    • LoRusso P.M., Jones S.F., Koch K.M., et al. Phase I and pharmacokinetic study of lapatinib and docetaxel in patients with advanced cancer. J Clin Oncol 2008, 26:3051-3056.
    • (2008) J Clin Oncol , vol.26 , pp. 3051-3056
    • LoRusso, P.M.1    Jones, S.F.2    Koch, K.M.3
  • 68
    • 79251587195 scopus 로고    scopus 로고
    • Integrating bevacizumab, everolimus, and lapatinib into current neoadjuvant chemotherapy regimen for primary breast cancer. Safety results of the GeparQuinto trial
    • Von Minckwitz G., Eldtmann H., Loibl S., et al. Integrating bevacizumab, everolimus, and lapatinib into current neoadjuvant chemotherapy regimen for primary breast cancer. Safety results of the GeparQuinto trial. Ann Oncol 2011, 22:301-306.
    • (2011) Ann Oncol , vol.22 , pp. 301-306
    • Von Minckwitz, G.1    Eldtmann, H.2    Loibl, S.3
  • 69
    • 68749112912 scopus 로고    scopus 로고
    • Novel therapies in breast cancer: what is new from ASCO 2008
    • Chu D., Lu J. Novel therapies in breast cancer: what is new from ASCO 2008. J Hematol Oncol 2008, 1:16.
    • (2008) J Hematol Oncol , vol.1 , pp. 16
    • Chu, D.1    Lu, J.2
  • 70
    • 19044380618 scopus 로고    scopus 로고
    • Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
    • Agus D.B., Akita R.W., Fox W.D., et al. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell 2002, 2:127-137.
    • (2002) Cancer Cell , vol.2 , pp. 127-137
    • Agus, D.B.1    Akita, R.W.2    Fox, W.D.3
  • 71
    • 77949903478 scopus 로고    scopus 로고
    • Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy
    • Baselga J., Gelmon K.A., Verma S., et al. Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy. J Clin Oncol 2010, 28:1138-1144.
    • (2010) J Clin Oncol , vol.28 , pp. 1138-1144
    • Baselga, J.1    Gelmon, K.A.2    Verma, S.3
  • 72
    • 0030774045 scopus 로고    scopus 로고
    • Induction of apoptosis and cell cycle arrest by CP-358, 774, an inhibitor of epidermal growth factor receptor tyrosine kinase
    • Moyer J.D., Barbacci E.G., Iwata K.K., et al. Induction of apoptosis and cell cycle arrest by CP-358, 774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 1997, 57:4838-4848.
    • (1997) Cancer Res , vol.57 , pp. 4838-4848
    • Moyer, J.D.1    Barbacci, E.G.2    Iwata, K.K.3
  • 73
    • 0032695910 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358, 774: dynamics of receptor inhibition in situ and antitumor effects in athymic mice
    • Pollack V.A., Savage D.M., Baker D.A., et al. Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358, 774: dynamics of receptor inhibition in situ and antitumor effects in athymic mice. J Pharmacol Exp Ther 1999, 291:739-748.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 739-748
    • Pollack, V.A.1    Savage, D.M.2    Baker, D.A.3
  • 74
    • 0035398631 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies
    • Hidalgo M., Siu L.L., Nemunaitis J., et al. Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies. J Clin Oncol 2001, 19:3267-3279.
    • (2001) J Clin Oncol , vol.19 , pp. 3267-3279
    • Hidalgo, M.1    Siu, L.L.2    Nemunaitis, J.3
  • 75
    • 34249314346 scopus 로고    scopus 로고
    • Toxicity and outcome data in a phase II study of weekly docetaxel in combination with erlotinib in recurrent and/or metastatic breast cancer (MBC)
    • abstract 10623.
    • Kaur H, Silverman P, Singh D, et al. Toxicity and outcome data in a phase II study of weekly docetaxel in combination with erlotinib in recurrent and/or metastatic breast cancer (MBC). J Clin Oncol 2006;24(Suppl. 18):abstract 10623.
    • (2006) J Clin Oncol , vol.24 , Issue.SUPPL. 18
    • Kaur, H.1    Silverman, P.2    Singh, D.3
  • 76
    • 2442669093 scopus 로고    scopus 로고
    • Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with "standard of care" therapeutic agents for the treatment of breast cancer
    • Abrams T.J., Murray L.J., Pesenti E., et al. Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with "standard of care" therapeutic agents for the treatment of breast cancer. Mol Cancer Ther 2003, 2:1011-1021.
    • (2003) Mol Cancer Ther , vol.2 , pp. 1011-1021
    • Abrams, T.J.1    Murray, L.J.2    Pesenti, E.3
  • 77
    • 78149356321 scopus 로고    scopus 로고
    • Sunitinib in combination with docetaxel in patients with advanced solid tumors: a phase I dose-escalation study
    • Robert F., Sandler A., Schiller J.H., et al. Sunitinib in combination with docetaxel in patients with advanced solid tumors: a phase I dose-escalation study. Cancer Chemother Pharmacol 2010, 66:669-680.
    • (2010) Cancer Chemother Pharmacol , vol.66 , pp. 669-680
    • Robert, F.1    Sandler, A.2    Schiller, J.H.3
  • 78
    • 69749115052 scopus 로고    scopus 로고
    • Early experience with sunitinib, combined with docetaxel, in patients with metastatic breast cancer
    • Liljegren A., Bergh J., Castany R. Early experience with sunitinib, combined with docetaxel, in patients with metastatic breast cancer. Breast 2009, 18:259-262.
    • (2009) Breast , vol.18 , pp. 259-262
    • Liljegren, A.1    Bergh, J.2    Castany, R.3
  • 79
    • 69749108227 scopus 로고    scopus 로고
    • Sunitinib in breast cancer: friend or foe
    • Cardoso F., Senkus-Konefka E. Sunitinib in breast cancer: friend or foe. Breast 2009, 18:211-222.
    • (2009) Breast , vol.18 , pp. 211-222
    • Cardoso, F.1    Senkus-Konefka, E.2
  • 80
    • 33947144750 scopus 로고    scopus 로고
    • AG-013736, a novel inhibitor of VEGF receptor tyrosine kinases, inhibits breast cancer growth and decreases vascular permeability as detected by dynamic contrast-enhanced magnetic resonance imaging
    • Wilmes L.J., Pallavicini M.G., Fleming L.M., et al. AG-013736, a novel inhibitor of VEGF receptor tyrosine kinases, inhibits breast cancer growth and decreases vascular permeability as detected by dynamic contrast-enhanced magnetic resonance imaging. Magn Reson Imaging 2007, 25:319-327.
    • (2007) Magn Reson Imaging , vol.25 , pp. 319-327
    • Wilmes, L.J.1    Pallavicini, M.G.2    Fleming, L.M.3
  • 81
    • 58149337448 scopus 로고    scopus 로고
    • Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1-3
    • Hu-Lowe D.D., Zou H.Y., Grazzini M.L., et al. Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1-3. Clin Cancer Res 2008, 14:7272-7283.
    • (2008) Clin Cancer Res , vol.14 , pp. 7272-7283
    • Hu-Lowe, D.D.1    Zou, H.Y.2    Grazzini, M.L.3
  • 82
    • 79959286206 scopus 로고    scopus 로고
    • Randomized, placebo-controlled, double-blind, phase II study of axitinib plus docetaxel versus docetaxel plus placebo in patients with metastatic breast cancer
    • Rugo H.S., Stopeck A., Joy A.A., et al. Randomized, placebo-controlled, double-blind, phase II study of axitinib plus docetaxel versus docetaxel plus placebo in patients with metastatic breast cancer. J Clin Oncol 2011, 29:2459-2465.
    • (2011) J Clin Oncol , vol.29 , pp. 2459-2465
    • Rugo, H.S.1    Stopeck, A.2    Joy, A.A.3
  • 83
    • 18644383147 scopus 로고    scopus 로고
    • In vitro cytotoxic effects of imatinib in combination with anticancer drugs in human prostate cancer cell lines
    • Kübler H.R., van Randenborgh H., Treiber U., et al. In vitro cytotoxic effects of imatinib in combination with anticancer drugs in human prostate cancer cell lines. Prostate 2005, 63:385-394.
    • (2005) Prostate , vol.63 , pp. 385-394
    • Kübler, H.R.1    van Randenborgh, H.2    Treiber, U.3
  • 84
    • 79954917723 scopus 로고    scopus 로고
    • Docetaxel metabolism is not altered by imatinib: findings from an early phase study in metastatic breast cancer
    • Connolly R.M., Rudek M.A., Garrett-Mayer E., et al. Docetaxel metabolism is not altered by imatinib: findings from an early phase study in metastatic breast cancer. Breast Cancer Res Treat 2011, 127:153-162.
    • (2011) Breast Cancer Res Treat , vol.127 , pp. 153-162
    • Connolly, R.M.1    Rudek, M.A.2    Garrett-Mayer, E.3
  • 85
    • 79551532836 scopus 로고    scopus 로고
    • A phase I/II study of imatinib and docetaxel as neoadjuvant therapy in locally advanced breast cancer
    • abstract 11039.
    • Haley BB, Ashfaq R, DeHaas M, Ramaswami A, Sikder K, Tripathy D. A phase I/II study of imatinib and docetaxel as neoadjuvant therapy in locally advanced breast cancer. J Clin Oncol 2007;25(Suppl.):abstract 11039.
    • (2007) J Clin Oncol , vol.25 , Issue.SUPPL.
    • Haley, B.B.1    Ashfaq, R.2    DeHaas, M.3    Ramaswami, A.4    Sikder, K.5    Tripathy, D.6
  • 86
    • 20244365941 scopus 로고    scopus 로고
    • The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation
    • Beuvink I., Boulay A., Fumagalli S., et al. The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation. Cell 2005, 120:747-759.
    • (2005) Cell , vol.120 , pp. 747-759
    • Beuvink, I.1    Boulay, A.2    Fumagalli, S.3
  • 87
    • 22344446415 scopus 로고    scopus 로고
    • Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer
    • Boulay A., Rudloff J., Ye J., et al. Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer. Clin Cancer Res 2005, 11:5319-5328.
    • (2005) Clin Cancer Res , vol.11 , pp. 5319-5328
    • Boulay, A.1    Rudloff, J.2    Ye, J.3
  • 88
    • 24644447853 scopus 로고    scopus 로고
    • Enhanced radiation damage of tumor vasculature by mTOR inhibitors
    • Shinohara E.T., Cao C., Niermann K., et al. Enhanced radiation damage of tumor vasculature by mTOR inhibitors. Oncogene 2005, 24:5414-5422.
    • (2005) Oncogene , vol.24 , pp. 5414-5422
    • Shinohara, E.T.1    Cao, C.2    Niermann, K.3
  • 89
    • 33646762376 scopus 로고    scopus 로고
    • Differential anti-vascular effects of mTOR or VEGFR pathway inhibition: a rational basis for combining RAD001, PTK787/ZK222584
    • [Abstract 3038]
    • O'Reilly T.M., Wood J.M., Amanda L.-E., et al. Differential anti-vascular effects of mTOR or VEGFR pathway inhibition: a rational basis for combining RAD001, PTK787/ZK222584. Proc Am Assoc Cancer Res 2005, 46:715. [Abstract 3038].
    • (2005) Proc Am Assoc Cancer Res , vol.46 , pp. 715
    • O'Reilly, T.M.1    Wood, J.M.2    Amanda, L.-E.3
  • 90
    • 79952173767 scopus 로고    scopus 로고
    • Phase I trial of escalating doses of weekly everolimus (RAD001) in combination with docetaxel for the treatment of metastatic breast cancer (MBC)
    • abstract 1066.
    • Moulder SL, Rivera E, Ensor J, et al. Phase I trial of escalating doses of weekly everolimus (RAD001) in combination with docetaxel for the treatment of metastatic breast cancer (MBC). J Clin Oncol 2009;27(Suppl. 15):abstract 1066.
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL. 15
    • Moulder, S.L.1    Rivera, E.2    Ensor, J.3
  • 91
    • 1842614245 scopus 로고    scopus 로고
    • Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progression
    • Tripathy D., Slamon D.J., Cobleigh M., et al. Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progression. J Clin Oncol 2004, 22:1063-1070.
    • (2004) J Clin Oncol , vol.22 , pp. 1063-1070
    • Tripathy, D.1    Slamon, D.J.2    Cobleigh, M.3
  • 92
    • 33645792831 scopus 로고    scopus 로고
    • Outcome of patients with HER2-positive advanced breast cancer progressing during trastuzumab-based therapy
    • Montemurro F., Donadio M., Clavarezza M., et al. Outcome of patients with HER2-positive advanced breast cancer progressing during trastuzumab-based therapy. Oncologist 2006, 11:318-324.
    • (2006) Oncologist , vol.11 , pp. 318-324
    • Montemurro, F.1    Donadio, M.2    Clavarezza, M.3
  • 93
    • 73949139238 scopus 로고    scopus 로고
    • How to treat hormone receptor-positive, human epidermal growth factor receptor 2-amplified breast cancer
    • Cortes J., Baselga J. How to treat hormone receptor-positive, human epidermal growth factor receptor 2-amplified breast cancer. J Clin Oncol 2009, 27:5492-5494.
    • (2009) J Clin Oncol , vol.27 , pp. 5492-5494
    • Cortes, J.1    Baselga, J.2
  • 94
    • 84861199951 scopus 로고    scopus 로고
    • Genentech press release July 2011: Pertuzumab combined with herceptin and chemotherapy significantly extended the time people with HER2-positive metastatic breast cancer lived without their disease getting worse
    • Genentech press release July 2011: Pertuzumab combined with herceptin and chemotherapy significantly extended the time people with HER2-positive metastatic breast cancer lived without their disease getting worse http://www.gene.com.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.