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Volumn 47, Issue 16, 2011, Pages 2387-2395

Efficacy and safety of bevacizumab in combination with docetaxel for the first-line treatment of elderly patients with locally recurrent or metastatic breast cancer: Results from AVADO

(11)  Pivot, Xavier a   Schneeweiss, Andreas b   Verma, Shailendra c   Thomssen, Christoph d   Passos Coelho, José Luis e   Benedetti, Giovanni f   Ciruelos, Eva g   Von Moos, Roger h   Chang, Hong Tai i   Duenne, Anja Alexandra j   Miles, David W k  


Author keywords

Bevacizumab; Docetaxel; Elderly; Metastatic breast cancer; Taxane

Indexed keywords

ANTHRACYCLINE DERIVATIVE; ANTIHYPERTENSIVE AGENT; BEVACIZUMAB; DOCETAXEL; PLACEBO; TAXANE DERIVATIVE;

EID: 80054883209     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2011.06.018     Document Type: Article
Times cited : (104)

References (39)
  • 1
    • 34249789073 scopus 로고    scopus 로고
    • Treating advanced breast cancer in the older woman
    • M. Extermann Treating advanced breast cancer in the older woman Oncology 20 2009 1355 1360
    • (2009) Oncology , vol.20 , pp. 1355-1360
    • Extermann, M.1
  • 2
    • 0041382815 scopus 로고    scopus 로고
    • Diagnosis and treatment of breast cancer in the elderly
    • C.E. Holmes, and H.B. Muss Diagnosis and treatment of breast cancer in the elderly CA Cancer J Clin 53 2003 227 244 (Pubitemid 37045791)
    • (2003) Ca-A Cancer Journal for Clinicians , vol.53 , Issue.4 , pp. 227-244
    • Holmes, C.E.1    Muss, H.B.2
  • 3
    • 0034607235 scopus 로고    scopus 로고
    • Tumor characteristics and clinical outcome of elderly women with breast cancer
    • S.G. Diab, R.M. Elledge, and G.M. Clark Tumor characteristics and clinical outcome of elderly women with breast cancer J Natl Cancer Inst 92 2000 550 556 (Pubitemid 30212316)
    • (2000) Journal of the National Cancer Institute , vol.92 , Issue.7 , pp. 550-556
    • Diab, S.G.1    Elledge, R.M.2    Clark, G.M.3
  • 6
    • 70350678858 scopus 로고    scopus 로고
    • Better treatment for breast cancer in older patients
    • P. Tran, and I.S. Fentiman Better treatment for breast cancer in older patients Expert Rev Anticancer Ther 9 2009 1081 1090
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 1081-1090
    • Tran, P.1    Fentiman, I.S.2
  • 7
    • 47349113208 scopus 로고    scopus 로고
    • NCCN Task Force Report: Breast cancer in the older woman
    • R.W. Carlson, S. Moench, and A. Hurria NCCN Task Force Report: breast cancer in the older woman J Natl Compr Canc Netw 8 Suppl. 4 2008 S1 S25
    • (2008) J Natl Compr Canc Netw , vol.8 , Issue.SUPPL. 4
    • Carlson, R.W.1    Moench, S.2    Hurria, A.3
  • 8
    • 70349335347 scopus 로고    scopus 로고
    • Management of primary and advanced breast cancer in older unfit patients (medical treatment)
    • M. Aapro, S. Monfardini, and A. Jirillo Management of primary and advanced breast cancer in older unfit patients (medical treatment) Cancer Treat Rev 35 2009 503 508
    • (2009) Cancer Treat Rev , vol.35 , pp. 503-508
    • Aapro, M.1    Monfardini, S.2    Jirillo, A.3
  • 11
    • 21844462141 scopus 로고    scopus 로고
    • Single agent versus combination chemotherapy for metastatic breast cancer
    • Carrick S, Parker S, Wilcken N, et al. Single agent versus combination chemotherapy for metastatic breast cancer. Cochrane Database Syst Rev 2005; CD003372.
    • (2005) Cochrane Database Syst Rev
    • Carrick, S.1    Parker, S.2    Wilcken, N.3
  • 12
    • 77953014467 scopus 로고    scopus 로고
    • Bevacizumab in combination with taxanes for the first-line treatment of metastatic breast cancer
    • A. Chan, D. Miles, and X. Pivot Bevacizumab in combination with taxanes for the first-line treatment of metastatic breast cancer Ann Oncol 21 2010 2305 2315
    • (2010) Ann Oncol , vol.21 , pp. 2305-2315
    • Chan, A.1    Miles, D.2    Pivot, X.3
  • 13
    • 77954700380 scopus 로고    scopus 로고
    • Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
    • D.W. Miles, A. Chan, and L.Y. Dirix Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer J Clin Oncol 28 2010 3229 3247
    • (2010) J Clin Oncol , vol.28 , pp. 3229-3247
    • Miles, D.W.1    Chan, A.2    Dirix, L.Y.3
  • 14
    • 77953538055 scopus 로고    scopus 로고
    • Clinical benefit of bevacizumab (BV) + first-line docetaxel (D) in elderly patients (pts) with locally-recurrent (LR) or metastatic breast cancer (MBC): AVADO study
    • X. Pivot, S. Verma, and C. Thomssen Clinical benefit of bevacizumab (BV) + first-line docetaxel (D) in elderly patients (pts) with locally-recurrent (LR) or metastatic breast cancer (MBC): AVADO study J Clin Oncol 27 15 2009 1094
    • (2009) J Clin Oncol , vol.27 , Issue.15 , pp. 1094
    • Pivot, X.1    Verma, S.2    Thomssen, C.3
  • 15
    • 77955002643 scopus 로고    scopus 로고
    • How does older age influence oncologists' cancer management?
    • J.A. Foster, G.D. Salinas, and D. Mansell How does older age influence oncologists' cancer management? Oncologist 15 2010 584 592
    • (2010) Oncologist , vol.15 , pp. 584-592
    • Foster, J.A.1    Salinas, G.D.2    Mansell, D.3
  • 16
    • 58049198447 scopus 로고    scopus 로고
    • Chemotherapy and targeted agents for elderly women with advanced breast cancer
    • A. Brunello, A. Roma, and C. Falci Chemotherapy and targeted agents for elderly women with advanced breast cancer Recent Pat Anticancer Drug Discov 3 2008 187 201
    • (2008) Recent Pat Anticancer Drug Discov , vol.3 , pp. 187-201
    • Brunello, A.1    Roma, A.2    Falci, C.3
  • 17
    • 33745147264 scopus 로고    scopus 로고
    • Management of cancer in the elderly
    • L. Balducci Management of cancer in the elderly Oncology 20 2006 135 143 (Pubitemid 46931060)
    • (2006) Oncology , vol.20 , Issue.2 , pp. 135-143
    • Balducci, L.1
  • 18
    • 0036892113 scopus 로고    scopus 로고
    • Prescribing anti-cancer drugs in elderly cancer patients
    • DOI 10.1016/S0959-8049(02)00266-6, PII S0959804902002666
    • S. Monfardini Prescribing anti-cancer drugs in elderly cancer patients Eur J Cancer 38 2002 2341 2346 (Pubitemid 35387485)
    • (2002) European Journal of Cancer , vol.38 , Issue.18 , pp. 2341-2346
    • Monfardini, S.1
  • 19
    • 0037441856 scopus 로고    scopus 로고
    • Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: An Intergroup trial (E1193)
    • DOI 10.1200/JCO.2003.08.013
    • G.W. Sledge, D. Neuberg, and P. Bernardo Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: an intergroup trial (E1193) J Clin Oncol 21 2003 588 592 (Pubitemid 46621890)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.4 , pp. 588-592
    • Sledge, G.W.1    Neuberg, D.2    Bernardo, P.3    Ingle, J.N.4    Martino, S.5    Rowinsky, E.K.6    Wood, W.C.7
  • 20
    • 84857055034 scopus 로고    scopus 로고
    • Treating elderly patients with breast cancer
    • [ ]
    • R. Jones, and R.C.F. Leonard Treating elderly patients with breast cancer Breast Cancer Online 8 4 2005 [ www.bco.org ]
    • (2005) Breast Cancer Online , vol.8 , Issue.4
    • Jones, R.1    Leonard, R.C.F.2
  • 21
    • 70349871302 scopus 로고    scopus 로고
    • Adverse drug events in the elderly: An ongoing problem
    • L. Charnelda, C.L. Gray, and C. Gardner Adverse drug events in the elderly: an ongoing problem J Manag Care Pharm 15 2009 568 571
    • (2009) J Manag Care Pharm , vol.15 , pp. 568-571
    • Charnelda, L.1    Gray, C.L.2    Gardner, C.3
  • 22
    • 73349120007 scopus 로고    scopus 로고
    • Independent review of E2100: A phase III trial of bevacizumab plus paclitaxel versus paclitaxel in women with metastatic breast cancer
    • R. Gray, S. Bhattacharya, and C. Bowden Independent review of E2100: A phase III trial of bevacizumab plus paclitaxel versus paclitaxel in women with metastatic breast cancer J Clin Oncol 27 2009 4966 4972
    • (2009) J Clin Oncol , vol.27 , pp. 4966-4972
    • Gray, R.1    Bhattacharya, S.2    Bowden, C.3
  • 23
    • 77949686134 scopus 로고    scopus 로고
    • Comparison of subgroup analyses of PFS from three phase III studies of bevacizumab in combination with chemotherapy in patients with HER2-negative metastatic breast cancer
    • [Abstract 207]
    • J. O'Shaughnessy, V. Diéras, and J. Glaspy Comparison of subgroup analyses of PFS from three phase III studies of bevacizumab in combination with chemotherapy in patients with HER2-negative metastatic breast cancer Cancer Res 69 2009 512s [Abstract 207]
    • (2009) Cancer Res , vol.69
    • O'Shaughnessy, J.1    Diéras, V.2    Glaspy, J.3
  • 24
    • 79953874259 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab (B) for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer
    • N.J. Robert, V. Dieras, and J. Glaspy Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab (B) for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer J Clin Oncol 29 2011 1252 1260
    • (2011) J Clin Oncol , vol.29 , pp. 1252-1260
    • Robert, N.J.1    Dieras, V.2    Glaspy, J.3
  • 25
    • 80052568716 scopus 로고    scopus 로고
    • Bevacizumab in combination with chemotherapy in the treatment of HER2-metastatic breast cancer: PFS subgroup results from two phase III studies
    • J. Glaspy, V. Dieras, and A. Brufsky Bevacizumab in combination with chemotherapy in the treatment of HER2-metastatic breast cancer: PFS subgroup results from two phase III studies Eur J Cancer Suppl 8 2010 202
    • (2010) Eur J Cancer Suppl , vol.8 , pp. 202
    • Glaspy, J.1    Dieras, V.2    Brufsky, A.3
  • 26
    • 74649083066 scopus 로고    scopus 로고
    • Tolerability and efficacy of first-line bevacizumab (B) plus chemotherapy (CT) in elderly patients with advanced breast cancer (aBC): Subpopulation analysis of the MO19391 study
    • [abstract 1032]
    • L. Biganzoli, H. Cortes-Funes, and C. Thomssen Tolerability and efficacy of first-line bevacizumab (B) plus chemotherapy (CT) in elderly patients with advanced breast cancer (aBC): Subpopulation analysis of the MO19391 study J Clin Oncol 27 2009 48s [abstract 1032]
    • (2009) J Clin Oncol , vol.27
    • Biganzoli, L.1    Cortes-Funes, H.2    Thomssen, C.3
  • 27
    • 59949103464 scopus 로고    scopus 로고
    • First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: Safety and efficacy in an open-label study in 2251 patients
    • [Epub ahead of print]
    • Smith IE, Pierga JY, Biganzoli L, et al. First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: safety and efficacy in an open-label study in 2251 patients. Ann Oncol 2010 [Epub ahead of print].
    • (2010) Ann Oncol
    • Smith, I.E.1    Pierga, J.Y.2    Biganzoli, L.3
  • 28
    • 71549143528 scopus 로고    scopus 로고
    • Detecting an overall survival benefit that is derived from progression-free survival
    • K.R. Broglio, and D.A. Berry Detecting an overall survival benefit that is derived from progression-free survival J Natl Cancer Inst 101 2009 1642 1649
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1642-1649
    • Broglio, K.R.1    Berry, D.A.2
  • 31
    • 70249129810 scopus 로고    scopus 로고
    • Doxorubicin and paclitaxel versus fluorouracil, doxorubicin and cyclophosphamide as first-line therapy for women with advanced breast cancer: Long-term analysis of the previously published trial
    • J. Jassem, T. Pienkowski, and A. Pluzanska Doxorubicin and paclitaxel versus fluorouracil, doxorubicin and cyclophosphamide as first-line therapy for women with advanced breast cancer: long-term analysis of the previously published trial Onkologie 32 2009 468 472
    • (2009) Onkologie , vol.32 , pp. 468-472
    • Jassem, J.1    Pienkowski, T.2    Pluzanska, A.3
  • 32
    • 0037445247 scopus 로고    scopus 로고
    • Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: Results of a randomized, multicenter, phase III trial
    • J.M. Nabholtz, C. Falkson, and D. Campos Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: results of a randomized, multicenter, phase III trial Br J Cancer 91 2004 968 975
    • (2004) Br J Cancer , vol.91 , pp. 968-975
    • Nabholtz, J.M.1    Falkson, C.2    Campos, D.3
  • 33
    • 77954287878 scopus 로고    scopus 로고
    • Epirubicin and cyclophosphamide versus epirubicin and docetaxel as first-line therapy for women with metastatic breast cancer: Final results of a randomised phase III trial
    • J.U. Blohmer, P. Schmid, and J. Hilfrich Epirubicin and cyclophosphamide versus epirubicin and docetaxel as first-line therapy for women with metastatic breast cancer: final results of a randomised phase III trial Ann Oncol 21 2010 1430 1435
    • (2010) Ann Oncol , vol.21 , pp. 1430-1435
    • Blohmer, J.U.1    Schmid, P.2    Hilfrich, J.3
  • 35
    • 33644680299 scopus 로고    scopus 로고
    • Phase III trial of epirubicin plus paclitaxel compared with epirubicin plus cyclophosphamide as first-line chemotherapy for metastatic breast cancer. United Kingdom National Cancer Research Institute trial AB01
    • R.E. Langley, J. Carmichael, and A.L. Jones Phase III trial of epirubicin plus paclitaxel compared with epirubicin plus cyclophosphamide as first-line chemotherapy for metastatic breast cancer. United Kingdom National Cancer Research Institute trial AB01 J Clin Oncol 23 2005 8322 8330
    • (2005) J Clin Oncol , vol.23 , pp. 8322-8330
    • Langley, R.E.1    Carmichael, J.2    Jones, A.L.3
  • 36
    • 50549096593 scopus 로고    scopus 로고
    • Gemcitabine plus paclitaxel versus paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment
    • K.S. Albain, S.M. Nag, and G. Calderillo-Ruiz Gemcitabine plus paclitaxel versus paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment J Clin Oncol 26 2008 3950 3957
    • (2008) J Clin Oncol , vol.26 , pp. 3950-3957
    • Albain, K.S.1    Nag, S.M.2    Calderillo-Ruiz, G.3
  • 39
    • 79958043675 scopus 로고    scopus 로고
    • National Cancer Institute. Bethesda, MD, based on November 2010 SEER data submission, posted to the SEER web site
    • Howlader N, Noone AM, Krapcho M, et al. SEER cancer statistics review, 1975-2008. National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/ 1975-2008/, based on November 2010 SEER data submission, posted to the SEER web site; 2011.
    • (2011) SEER Cancer Statistics Review, 1975-2008
    • Howlader, N.1    Noone, A.M.2    Krapcho, M.3


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