Treatment with progesterone after focal cerebral ischemia suppresses proliferation of progenitor cells but enhances survival of newborn neurons in adult male mice

Neuropharmacology

Volumn 58, Issue 6, 2010, Pages 930-939

  Zhang, Zhuo ^a,b   Yang, Rong ^a   Cai, Weiyan ^a   Bai, Yingyang ^a   Sokabe, Masahiro ^c,d   Chen, Ling ^a,c  

^a NANJING MEDICAL UNIVERSITY   (China)

^b THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Extracellular receptor kinase (ERK); Middle cerebral artery occlusion (MCAO); Neurogenesis; Progesterone (P4); Progesterone receptor (P4R)

Indexed keywords

FINASTERIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROGESTERONE; PROGESTERONE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN NERVE CELL; CELL LABELING; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG MECHANISM; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

ADULT STEM CELLS; ANIMALS; BRAIN; BRAIN ISCHEMIA; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CORPUS STRIATUM; DENTATE GYRUS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MAP KINASE SIGNALING SYSTEM; MICE; NEUROGENESIS; NEURONS; NEUROPROTECTIVE AGENTS; PREGNANOLONE; PROGESTERONE; STEM CELL NICHE; TIME FACTORS;

EID: 77649336300     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.01.002     Document Type: Article

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