LINGO-2 polymorphism and the risk of Parkinson's disease in Taiwan

Parkinsonism and Related Disorders

Volumn 18, Issue 5, 2012, Pages 609-611

  Su, Feng Chieh ^a   Chen, Chiung Mei ^a   Chen, Yi Chun ^a   Wu, Yih Ru ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

LINGO 2; Parkinson's disease; Polymorphism

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; ETHNIC GROUP; FEMALE; GENE; GENE FREQUENCY; GENETIC ANALYSIS; GENOTYPE; HUMAN; LINGO 2 GENE; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; TAIWAN; TAIWANESE;

ADULT; AGED; AGED, 80 AND OVER; CELL ADHESION MOLECULES, NEURONAL; CHI-SQUARE DISTRIBUTION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; POLYMORPHISM, SINGLE NUCLEOTIDE; TAIWAN; YOUNG ADULT;

EID: 84861182232     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2011.11.013     Document Type: Article

References (12)

1. Hardy J., Lewis P., Revesz T., Lees A., Paisan-Ruiz C. The genetics of Parkinson's syndromes: a critical review. Curr Opin Genet Dev 2009, 19:254-265.
2. Carim-Todd L., Escarceller M., Estivill X., Sumoy L. LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex. Eur J Neurosci 2003, 18:3167-3182.
3. Mi S., Lee X., Shao Z., Thill G., Ji B., Relton J., et al. LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex. Nat Neurosci 2004, 7:221-228.
4. Inoue H., Lin L., Lee X., Shao Z., Mendes S., Snodgrass-Belt P., et al. Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models. Proc Natl Acad Sci USA 2007, 104:14430-14435.
5. Homma S., Shimada T., Hikake T., Yaginuma H. Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo. Gene Expr Patterns 2009, 9:1-26.
6. Vilarino-Guell C., Wider C., Ross O.A., Jasinska-Myga B., Kachergus J., Cobb S.A., et al. LINGO1 and LINGO2 variants are associated with essential tremor and Parkinson disease. Neurogenetics 2010, 11:401-408.
7. Haubenberger D., Hotzy C., Pirker W., Katzenschlager R., Brucke T., Zimprich F., et al. Role of LINGO1 polymorphisms in Parkinson's disease. Mov Disord 2009, 24:2404-2407.
8. Bialecka M., Kurzawski M., Tan E.K., Drozdzik M. Analysis of LINGO1 (rs9652490) polymorphism in sporadic Parkinson's disease in a Polish population, and a meta-analysis. Neurosci Lett 2010, 472:53-55.
9. Wu Y.R., Tan E.K., Chen C.M., Kumar P.M., Lee-Chen G.J., Chen S.T. Genetic analysis of "leucine-rich repeat (LRR) and immunoglobulin (Ig) domain-containing, Nogo receptor-interacting protein-1 (LINGO1)" in two independent Chinese parkinson's disease populations. Am J Med Genet B Neuropsychiatr Genet 2011, 156:99-103.
10. Wu Y.W., Prakash K.M., Rong T.Y., Li H.H., Xiao Q., Tan L.C., et al. Lingo2 variants associated with essential tremor and Parkinson's disease. Hum Genet 2011, 129:611-615.
11. Satake W., Nakabayashi Y., Mizuta I., Hirota Y., Ito C., Kubo, et al. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat Genet 2009, 41:1303-1307.
12. Simon-Sanchez J., Schulte C., Bras J.M., Sharma M., Simón-Sánchez J., Schulte C., et al. Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet 2009, 41:1308-1312.