메뉴 건너뛰기




Volumn 156, Issue 10, 2012, Pages 746-747

Ethical dilemmas and malfunctions in clinical trials research

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DRONEDARONE; TORCETRAPIB;

EID: 84861163751     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/0003-4819-156-10-201205150-00015     Document Type: Editorial
Times cited : (7)

References (16)
  • 1
    • 84861124020 scopus 로고    scopus 로고
    • A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations. A randomized, controlled trial
    • Fan VS, Gaziano JM, Lew R, Bourbeau J, Adams SG, Leatherman S, et al. A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations. A randomized, controlled trial. Ann Intern Med. 2012;156:673-83.
    • (2012) Ann Intern Med , vol.156 , pp. 673-683
    • Fan, V.S.1    Gaziano, J.M.2    Lew, R.3    Bourbeau, J.4    Adams, S.G.5    Leatherman, S.6
  • 2
    • 22144431885 scopus 로고    scopus 로고
    • Contradicted and initially stronger effects in highly cited clinical research
    • Ioannidis JP. Contradicted and initially stronger effects in highly cited clinical research. JAMA. 2005;294:218-28.
    • (2005) JAMA , vol.294 , pp. 218-228
    • Ioannidis, J.P.1
  • 3
    • 36849062123 scopus 로고    scopus 로고
    • Current controversies in data monitoring for clinical trials
    • Pocock SJ. Current controversies in data monitoring for clinical trials. Clin Trials. 2006;3:513-21.
    • (2006) Clin Trials , vol.3 , pp. 513-521
    • Pocock, S.J.1
  • 4
    • 0033524162 scopus 로고    scopus 로고
    • The agonising negative trend in monitoring of clinical trials
    • DeMets DL, Pocock SJ, Julian DG. The agonising negative trend in monitoring of clinical trials. Lancet. 1999;354:1983-8.
    • (1999) Lancet , vol.354 , pp. 1983-1988
    • Demets, D.L.1    Pocock, S.J.2    Julian, D.G.3
  • 5
    • 45149131667 scopus 로고    scopus 로고
    • Action to Control Cardiovascular Risk in Diabetes Study Group. Effects of intensive glucose lowering in type 2 diabetes
    • Gerstein HC, Miller ME, Byington RP, Goff DC Jr, Bigger JT, Buse JB, et al; Action to Control Cardiovascular Risk in Diabetes Study Group. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med. 2008;358:2545-59.
    • (2008) N Engl J Med , vol.358 , pp. 2545-2559
    • Gerstein, H.C.1    Miller, M.E.2    Byington, R.P.3    Goff Jr., D.C.4    Bigger, J.T.5    Buse, J.B.6
  • 6
    • 65649106228 scopus 로고    scopus 로고
    • Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: A meta-analysis of randomised controlled trials
    • Ray KK, Seshasai SR, Wijesuriya S, Sivakumaran R, Nethercott S, Preiss D, et al. Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials. Lancet. 2009;373:1765-72.
    • (2009) Lancet , vol.373 , pp. 1765-1772
    • Ray, K.K.1    Seshasai, S.R.2    Wijesuriya, S.3    Sivakumaran, R.4    Nethercott, S.5    Preiss, D.6
  • 7
    • 36348975228 scopus 로고    scopus 로고
    • ILLUMINATE Investigators. Effects of torcetrapib in patients at high risk for coronary events
    • Barter PJ, Caulfield M, Eriksson M, Grundy SM, Kastelein JJ, Komajda M, et al; ILLUMINATE Investigators. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. 2007;357:2109-22.
    • (2007) N Engl J Med , vol.357 , pp. 2109-2122
    • Barter, P.J.1    Caulfield, M.2    Eriksson, M.3    Grundy, S.M.4    Kastelein, J.J.5    Komajda, M.6
  • 9
    • 5044223264 scopus 로고    scopus 로고
    • CRASH trial collaborators. Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): Randomised placebo-controlled trial
    • Roberts I, Yates D, Sandercock P, Farrell B, Wasserberg J, Lomas G, et al; CRASH trial collaborators. Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial. Lancet. 2004;364:1321-8.
    • (2004) Lancet , vol.364 , pp. 1321-1328
    • Roberts, I.1    Yates, D.2    Sandercock, P.3    Farrell, B.4    Wasserberg, J.5    Lomas, G.6
  • 10
    • 0026660156 scopus 로고
    • When to stop a clinical trial
    • Pocock SJ. When to stop a clinical trial. BMJ. 1992;305:235-40.
    • (1992) BMJ , vol.305 , pp. 235-240
    • Pocock, S.J.1
  • 11
    • 84861112351 scopus 로고    scopus 로고
    • How variability in the institutional review board review process affects minimal-risk multisite health services research
    • Petersen LA, Simpson K, SoRelle R, Urech T, Chitwood SS. How variability in the institutional review board review process affects minimal-risk multisite health services research. Ann Intern Med. 2012;156:728-35.
    • (2012) Ann Intern Med , vol.156 , pp. 728-735
    • Petersen, L.A.1    Simpson, K.2    Sorelle, R.3    Urech, T.4    Chitwood, S.S.5
  • 12
    • 0038324444 scopus 로고    scopus 로고
    • The ethical bureaucracy [Editorial]
    • Martyn C. The ethical bureaucracy [Editorial]. QJM. 2003;96:323-4.
    • (2003) QJM , vol.96 , pp. 323-324
    • Martyn, C.1
  • 13
    • 84855833379 scopus 로고    scopus 로고
    • Exposing unethical human research: The transatlantic correspondence of Beecher and Pappworth
    • Gaw A. Exposing unethical human research: the transatlantic correspondence of Beecher and Pappworth. Ann Intern Med. 2012;156:150-5.
    • (2012) Ann Intern Med , vol.156 , pp. 150-155
    • Gaw, A.1
  • 14
    • 27144480342 scopus 로고    scopus 로고
    • Research ethics committees in the UK-the pressure is now on research and development departments
    • Al-Shahi R. Research ethics committees in the UK-the pressure is now on research and development departments. J R Soc Med. 2005;98:444-7.
    • (2005) J R Soc Med , vol.98 , pp. 444-447
    • Al-Shahi, R.1
  • 15
    • 34447314711 scopus 로고    scopus 로고
    • Clinical trials bureaucracy: Unintended consequences of wellintentioned policy
    • Califf RM. Clinical trials bureaucracy: unintended consequences of wellintentioned policy. Clin Trials. 2006;3:496-502.
    • (2006) Clin Trials , vol.3 , pp. 496-502
    • Califf, R.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.