메뉴 건너뛰기




Volumn 88, Issue 4, 2012, Pages 548-554

5-fluorouracil accumulation in green microalgae and its biogenetic transfer into ciliate protozoan

Author keywords

Bioaccumulation Acute toxicity of 5 fluorouracil; Genetic transfer of 5 FU Microalgae

Indexed keywords

5-FLUOROURACIL; ACUTE TOXICITY; ANTICANCER DRUG; BIOACCUMULATION FACTOR; BIOTRANSFER; CELL PELLETS; FOOD VACUOLES; MICRO-ALGAE; SCENEDESMUS VACUOLATUS; TETRAHYMENA; TETRAHYMENA PYRIFORMIS;

EID: 84861161238     PISSN: 00074861     EISSN: 14320800     Source Type: Journal    
DOI: 10.1007/s00128-012-0536-8     Document Type: Article
Times cited : (7)

References (26)
  • 1
    • 6844251612 scopus 로고    scopus 로고
    • The anti-cancer drug 5-fluorouracil is metabolized by the isolated perfused rat liver and in rats into highly toxic fluoroacetate
    • Arellano M, Malet-Martino M, Martino R, Gires P (1998) The anti-cancer drug 5-fluorouracil is metabolized by the isolated perfused rat liver and in rats into highly toxic fluoroacetate. Brit J Can 77:79-86 (Pubitemid 28029776)
    • (1998) British Journal of Cancer , vol.77 , Issue.1 , pp. 79-86
    • Arellano, M.1    Malet-Martino, M.2    Martino, R.3    Gires, P.4
  • 2
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • Diasio RB, Harris BE (1989) Clinical pharmacology of 5-fluorouracil. Clin Pharmacokinet 16:215-237 (Pubitemid 19114713)
    • (1989) Clinical Pharmacokinetics , vol.16 , Issue.4 , pp. 215-237
    • Diasio, R.B.1    Harris, B.E.2
  • 3
    • 84953497024 scopus 로고
    • Analysis of phenoxy carboxylic acids and other acidic compounds in tap, ground, surface and sewage water at the low ppt level
    • Heberer T, Butz S, Stan H-J (1995) Analysis of phenoxy carboxylic acids and other acidic compounds in tap, ground, surface and sewage water at the low ppt level. Int J Environ Anal Chem 58:43-54
    • (1995) Int J Environ Anal Chem , vol.58 , pp. 43-54
    • Heberer, T.1    Butz, S.2    Stan, H.-J.3
  • 4
    • 0020072369 scopus 로고
    • Nucleotide levels and incorporation of 5-fluorouracil and uracil into DNA of cells treated with 5-fluorodeoxyuridine
    • Ingraham HA, Tseng BY, Goulian M (1982) Nucleotide levels and incorporation of 5-fluorouracil and uracil into DNA of cells treated with fluorodeoxyuridine. Mol Pharmacol 21:211-216 (Pubitemid 12177597)
    • (1982) Molecular Pharmacology , vol.21 , Issue.1 , pp. 211-216
    • Ingraham, H.A.1    Tseng, B.Y.2    Goulian, M.3
  • 5
    • 0000582243 scopus 로고    scopus 로고
    • Trace enrichment, chromatographic separation and biodegradation of cytostatic compounds in surface water
    • Kiffmeyer TK, Götze HJ, Jursch M, Lüders U (1998) Trace enrichment, chromatographic separation and biodegradation of cytostatic compounds in surface water. Fresenius Anal Chem 361:185-191 (Pubitemid 128790508)
    • (1998) Fresenius' Journal of Analytical Chemistry , vol.361 , Issue.2 , pp. 185-191
    • Kiffmeyer, T.1    Gotze, H.-J.2    Jursch, M.3    Luders, U.4
  • 7
    • 84862663342 scopus 로고
    • Biologic effect of 5-fluoro-20 deoxyribonucleic acid incorporation deoxyuridine in mammalian cells
    • Kufe DW, Scott P, Fram R, Major P (1983) Biologic effect of 5-fluoro-20 deoxyribonucleic acid incorporation deoxyuridine in mammalian cells. Mutat Res 258:161-188
    • (1983) Mutat Res , vol.258 , pp. 161-188
    • Kufe, D.W.1    Scott, P.2    Fram, R.3    Major, P.4
  • 8
    • 84862663343 scopus 로고    scopus 로고
    • Abbau von Arzneimitteln in Testsystemen und Möglichkeiten zur Emissionsreduktion
    • Weigert B, Steinberg Chr, Brüggemann R (eds), Berlin
    • Kümmerer K (1998) Abbau von Arzneimitteln in Testsystemen und Möglichkeiten zur Emissionsreduktion. In: Weigert B, Steinberg Chr, Brüggemann R (eds) Schriftenreihe Wasserforschung 6 Chemische Stressfaktoren in aquatischen Systemen, Berlin
    • (1998) Schriftenreihe Wasserforschung 6 Chemische Stressfaktoren in Aquatischen Systemen
    • Kümmerer, K.1
  • 10
    • 0034789817 scopus 로고    scopus 로고
    • Drugs in the environment: Emission of drugs, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources - A review
    • DOI 10.1016/S0045-6535(01)00144-8, PII S0045653501001448
    • Kümmerer K (2001) Drugs in the environment: emission of drugs, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources. Chemosphere 45:957-969 (Pubitemid 32947761)
    • (2001) Chemosphere , vol.45 , Issue.6-7 , pp. 957-969
    • Kummerer, K.1
  • 11
    • 0031295578 scopus 로고    scopus 로고
    • Biodegradability of the anti-tumor agents 5-fluorouracil, cytarabine, and gemcitabine: Impact of the chemical structure and synergistic toxicity with hospital effluent
    • Kümmerer K, Al-Ahmad A (1997) Biodegradability of the anti-tumor agents 5-fluorouracil, cytarabine, and gemcitabine: impact of the chemical structure and synergistic toxicity with hospital effluent. Acta hydrochim et hydrobiol 25:166-172
    • (1997) Acta Hydrochim et Hydrobiol , vol.25 , pp. 166-172
    • Kümmerer, K.1    Al-Ahmad, A.2
  • 12
    • 0038387494 scopus 로고    scopus 로고
    • 5-Fluorouracil: Mechanisms of action and clinical strategies
    • DOI 10.1038/nrc1074
    • Longley DB, Harkin DP, Johnston PG (2003) 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 3(5): 330-338 (Pubitemid 37328853)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.5 , pp. 330-338
    • Longley, D.B.1    Harkin, D.P.2    Johnston, P.G.3
  • 13
    • 33750976959 scopus 로고    scopus 로고
    • Fate of 5-fluorouracil, doxorubicin, epirubicin, and daunorubicin in hospital wastewater and their elimination by activated sludge and treatment in a membrane-bio-reactor system
    • DOI 10.1016/j.chemosphere.2006.05.051, PII S0045653506007156
    • Mahnik SN, Lenz K, Weissenbacher N, Mader R, Fuerhacker M (2007) Fate of 5-fluorouracil, doxorubicin, epirubicin, and daunorubicin in hospital wastewater and their elimination by activated sludge and treatment in a membrane-bio-reactor system. Chemosphere 66:30-37 (Pubitemid 44751888)
    • (2007) Chemosphere , vol.66 , Issue.1 , pp. 30-37
    • Mahnik, S.N.1    Lenz, K.2    Weissenbacher, N.3    Mader, R.M.4    Fuerhacker, M.5
  • 14
    • 0014421707 scopus 로고
    • Effect of cyclophosphamide and 5-fluorouracil on the synthesis of ribonucleic acid in yeast
    • Mayo VS, Andrean BAG, De Kloet SR (1968) Effect of cyclophosphamide and 5-fluorouracil on the synthesis of ribonucleic acid in yeast. Biochem et Biophy Acta 169:297-305
    • (1968) Biochem et Biophy Acta , vol.169 , pp. 297-305
    • Mayo, V.S.1    Andrean, B.A.G.2    De Kloet, S.R.3
  • 15
    • 0041431231 scopus 로고
    • The genetic toxicology of 5-fluoropyrimidines and 5-chlorouracil
    • DOI 10.1016/0165-1110(93)90006-9
    • Morris SM (1993) The genetic toxicology of 5-fluoropyrimidines and 5-chlorouracil. Mut Res 297:39-51 (Pubitemid 23181718)
    • (1993) Mutation Research - Reviews in Genetic Toxicology , vol.297 , Issue.1 , pp. 39-51
    • Morris, S.M.1
  • 16
    • 0041303650 scopus 로고    scopus 로고
    • Clinical implications of dihydropyrimidine dehydrogenase (DPD) activity in 5-FU-based chemotherapy: Mutations in the DPD gene, and DPD inhibitory fluoropyrimidines
    • DOI 10.1007/s10147-003-0330-z
    • Omura K (2003) Clinical implications of dihydropyrimidine dehydrogenase (DPD) activity in 5FU-based chemotherapy: mutations in the DPD gene and DPD inhibitory fluoropyrimidines. Int J Clin Oncol 8:132-138 (Pubitemid 36897282)
    • (2003) International Journal of Clinical Oncology , vol.8 , Issue.3 , pp. 132-138
    • Omura, K.1
  • 17
    • 2942648695 scopus 로고    scopus 로고
    • Four decades of continuing innovation with fluorouracil: Current and future approaches to fluorouracil chemoradiation therapy
    • DOI 10.1200/JCO.2004.08.009
    • Rich TA, Shepard RC, Mosley ST (2004) Four decades of continuing innovation with fluorouracil: current and future approaches to fluorouracil chemo-radiation therapy. J Clin Oncol 22:2214-2232 (Pubitemid 41095158)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.11 , pp. 2214-2232
    • Rich, T.A.1    Shepard, R.C.2    Mosley, S.T.3
  • 18
    • 0026524894 scopus 로고
    • Clinical pharmacokinetics of fluorouracil and folinic acid
    • Schalhorn A, Kuhl M (1992) Clinical pharmacokinetics of fluorouracil and folinic acid. Sem Oncol 19:82-92
    • (1992) Sem Oncol , vol.19 , pp. 82-92
    • Schalhorn, A.1    Kuhl, M.2
  • 19
    • 0022373281 scopus 로고
    • The effect of 5-fluorouracil on DNA chain elongation in intact bone marrow cells
    • DOI 10.1016/0006-291X(85)91884-4
    • Scheutz JD, Diasio RB (1985) The effect of 5-fluorouracil on DNA chain elongation in intact bone marrow cells. Biochem Biophy Res Commun 133:361-367 (Pubitemid 16155368)
    • (1985) Biochemical and Biophysical Research Communications , vol.133 , Issue.1 , pp. 361-367
    • Schuetz, J.D.1    Diasio, R.B.2
  • 21
    • 0032210734 scopus 로고    scopus 로고
    • Occurrence of drugs in German sewage treatment plants and rivers
    • Ternes T (1998) Occurrence of drugs in German sewage treatment plants and rivers. Water Res 32:245-3260
    • (1998) Water Res , vol.32 , pp. 245-3260
    • Ternes, T.1
  • 22
    • 84862699999 scopus 로고    scopus 로고
    • UBAFB (1996) Forschungsbericht des Umweltbundesamtes 102 06 514:95-075
    • UBAFB (1996) Forschungsbericht des Umweltbundesamtes 102 06 514:95-075
  • 23
    • 55749101746 scopus 로고    scopus 로고
    • Growth inhibition and biodegradation of catecholamines in the ciliated protozoan T pyriformis
    • Ud-Daula A, Pfister G, Schramm K-W (2008) Growth inhibition and biodegradation of catecholamines in the ciliated protozoan T. pyriformis. J Environ Sci Health Tox Hazard Subst Environ Eng. 43(14):1610-1617
    • (2008) J Environ Sci Health Tox Hazard Subst Environ Eng , vol.43 , Issue.14 , pp. 1610-1617
    • Ud-Daula, A.1    Pfister, G.2    Schramm, K.-W.3
  • 24
    • 73949120926 scopus 로고    scopus 로고
    • Impact of fluorotelomer alcohols (FTOH) on the molecular and macroscopic phenotype of Tetrahymena thermophila
    • doi:10.1007/s11356-009-0135-3
    • Wang Z, Ud-Daula A, Pfister G, Schramm K-W (2009) Impact of fluorotelomer alcohols (FTOH) on the molecular and macroscopic phenotype of Tetrahymena thermophila. J Environ Sci Poll Res Int. doi:10.1007/s11356-009-0135-3
    • (2009) J Environ Sci Poll Res Int
    • Wang, Z.1    Ud-Daula, A.2    Pfister, G.3    Schramm, K.-W.4
  • 26
    • 33846186322 scopus 로고    scopus 로고
    • Ecotoxicological evaluation of sodium fluoroacetate on aquatic organisms and investigation of the effects on two fish cell lines
    • DOI 10.1016/j.chemosphere.2006.10.027, PII S0045653506013555
    • Zurita JL, Jos A, Cameán AM, Salguero M, López- Artíguez M, Repetto G (2007) Ecotoxicological evaluation of sodium fluoroacetate on aquatic organisms and investigation of the effects on two fish cell lines. Chemosphere 67:1-12 (Pubitemid 46107559)
    • (2007) Chemosphere , vol.67 , Issue.1 , pp. 1-12
    • Zurita, J.L.1    Jos, A.2    Camean, A.M.3    Salguero, M.4    Lopez-Artiguez, M.5    Repetto, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.