Enhanced cellular uptake of a new, in silico identified antitubercular candidate by peptide conjugation

Bioconjugate Chemistry

Volumn 23, Issue 5, 2012, Pages 900-907

  Horváti, Kata ^a   Bacsa, Bernadett ^a   Szabó, Nóra ^b   Dávid, Sándor ^a,b   Mezo, Gábor ^a   Grolmusz, Vince ^c,f   Vértessy, Beáta ^d,e   Hudecz, Ferenc ^a,c   Bo'sze, Szilvia ^a  

^a EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^b NATIONAL KORANYI INSTITUTE OF PULMONOLOGY   (Hungary)

^c EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^d INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^e BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^f URATIM LTD   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOCHEMISTRY; CONTROLLED DRUG DELIVERY; DRUG DOSAGE; ENZYME ACTIVITY; ENZYME INHIBITION; MACROPHAGES; TARGETED DRUG DELIVERY;

'CURRENT; ANTI TUBERCULARS; ANTIMYCOBACTERIAL ACTIVITY; BACTERIA-RESISTANT; CELLULAR UPTAKE; DRUG CANDIDATES; IN-SILICO; M. TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; TUFTSIN;

PEPTIDES;

DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DRUG CARRIER; PEPTIDE DERIVATIVE; TB5 GRANF2 GRANULYSIN CONJUGATE; TB5 OT20 TUFTSIN CONJUGATE; TUBERCULOSTATIC AGENT; TUFTSIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CELL LINE; COMPUTER MODEL; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG UPTAKE; HUMAN; HUMAN CELL; MOLECULAR DOCKING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PEPTIDE SYNTHESIS;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

AMINO ACID SEQUENCE; ANTITUBERCULAR AGENTS; COMPUTER SIMULATION; DRUG DESIGN; HUMANS; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PEPTIDES; PYROPHOSPHATASES; TUBERCULOSIS;

EID: 84861109540     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc200221t     Document Type: Article

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