메뉴 건너뛰기




Volumn 14, Issue 3, 2012, Pages 244-251

Is rational antipsychotic polytherapy feasible? A selective review

Author keywords

Antipsychotic; Aripiprazole; Clozapine; Dopamine; Haloperidol; Polypharmacy; Polytherapy; Rational; Schizophrenia; Translational; Treatment refractory; Treatment resistant

Indexed keywords

AMISULPRIDE; ARIPIPRAZOLE; CHLORPROMAZINE; CHOLESTEROL; CLOZAPINE; GLUCOSE; HALOPERIDOL; NEUROLEPTIC AGENT; PLACEBO; PRECLAMOL; PROLACTIN; QUETIAPINE; RISPERIDONE; SULPIRIDE;

EID: 84861097976     PISSN: 15233812     EISSN: 15351645     Source Type: Journal    
DOI: 10.1007/s11920-012-0266-y     Document Type: Review
Times cited : (12)

References (66)
  • 1
    • 62849099049 scopus 로고    scopus 로고
    • How effective are second-generation antipsychotic drugs? A metaanalysis of placebo-controlled trials
    • Leucht S, Arbter D, Engel RR, Kissling W, Davis JM. How effective are second-generation antipsychotic drugs? A metaanalysis of placebo-controlled trials. Mol Psychiatry. 2009;14 (4):429-47.
    • (2009) Mol Psychiatry , vol.14 , Issue.4 , pp. 429-447
    • Leucht, S.1    Arbter, D.2    Engel, R.R.3    Kissling, W.4    Davis, J.M.5
  • 2
    • 0018880468 scopus 로고
    • Import issues in the drug treatment of schizophrenia
    • Davis JM, Schaffer CB, Killian GA, Kinard C, Chan C. Important issues in the drug treatment of schizophrenia. Schizophr Bull. 1980;6(1):70-87. (Pubitemid 10066395)
    • (1980) Schizophrenia Bulletin , vol.6 , Issue.1 , pp. 70-87
    • Davis, J.M.1    Schaffer, C.B.2    Killian, G.A.3
  • 3
    • 0031417026 scopus 로고    scopus 로고
    • Treatment-resistant schizophrenia - The role of clozapine
    • Meltzer HY. Treatment-resistant schizophrenia - the role of clozapine. Curr Med Res Opin. 1997;14(1):1-20. (Pubitemid 28080714)
    • (1997) Current Medical Research and Opinion , vol.14 , Issue.1 , pp. 1-20
    • Meltzer, H.Y.1
  • 6
    • 44849087549 scopus 로고    scopus 로고
    • Antipsychotic polypharmacy, part 1: Shotgun approach or targeted cotreatment?
    • Correll CU. Antipsychotic polypharmacy, part 1: shotgun approach or targeted cotreatment? J Clin Psychiatry. 2008;69 (4):674-5. (Pubitemid 351792345)
    • (2008) Journal of Clinical Psychiatry , vol.69 , Issue.4 , pp. 674-675
    • Correll, C.U.1
  • 7
    • 67349176083 scopus 로고    scopus 로고
    • Advantages and disadvantages of combination treatment with antipsychotics: ECNP Consensus Meeting March 2008, Nice
    • Goodwin G, Fleischhacker W, Arango C, Baumann P, Davidson M, de Hert M, et al. Advantages and disadvantages of combination treatment with antipsychotics: ECNP Consensus Meeting, March 2008, Nice. Eur Neuropsychopharmacol. 2009;19 (7):520-32.
    • (2009) Eur Neuropsychopharmacol , vol.19 , Issue.7 , pp. 520-532
    • Goodwin, G.1    Fleischhacker, W.2    Arango, C.3    Baumann, P.4    Davidson, M.5    De Hert, M.6
  • 8
    • 67649695935 scopus 로고    scopus 로고
    • Treatment of schizophrenia with antipsychotics in Norwegian emergency wards, a cross-sectional national study
    • Kroken R, Johnsen E, Ruud T, Wentzel-Larsen T, Jorgensen H. Treatment of schizophrenia with antipsychotics in Norwegian emergency wards, a cross-sectional national study. BMC Psychiatry. 2009;9:24.
    • (2009) BMC Psychiatry , vol.9 , pp. 24
    • Kroken, R.1    Johnsen, E.2    Ruud, T.3    Wentzel-Larsen, T.4    Jorgensen, H.5
  • 9
    • 79953859675 scopus 로고    scopus 로고
    • Antipsychotic polypharmacy in schizophrenia: Benefits and risks
    • Barnes TR, Paton C. Antipsychotic polypharmacy in schizophrenia: benefits and risks. CNS Drugs. 2011;25(5):383-99.
    • (2011) CNS Drugs , vol.25 , Issue.5 , pp. 383-399
    • Barnes, T.R.1    Paton, C.2
  • 10
    • 73949137552 scopus 로고    scopus 로고
    • The 2009 schizophrenia PORT psychopharmacological treatment recommendations and summary statements
    • Buchanan RW, Kreyenbuhl J,Kelly DL, Noel JM, BoggsDL, Fischer BA, et al. The 2009 Schizophrenia PORT Psychopharmacological Treatment Recommendations and Summary Statements. Schizophr Bull. 2010;36(1):71-93.
    • (2010) Schizophr Bull , vol.36 , Issue.1 , pp. 71-93
    • Buchanan, R.W.1    Kreyenbuhl, J.2    Kelly, D.L.3    Noel, J.M.4    Boggs, D.L.5    Fischer, B.A.6
  • 13
    • 44249083470 scopus 로고    scopus 로고
    • The "3 T's" road map to transform US Health Care
    • Dougherty D, Conway PH. The "3 T's" road map to transform US Health Care. JAMA. 2008;299(19):2319-21.
    • (2008) JAMA , vol.299 , Issue.19 , pp. 2319-2321
    • Dougherty, D.1    Conway, P.H.2
  • 14
    • 70449574214 scopus 로고    scopus 로고
    • A translational research approach to poor treatment response in patients with schizophrenia: Clozapine-antipsychotic polypharmacy
    • Honer WG, Procyshyn RM, Chen EY, MacEwan GW, Barr AM. A translational research approach to poor treatment response in patients with schizophrenia: clozapine-antipsychotic polypharmacy. J Psychiatry Neurosci. 2009;34(6):433-42.
    • (2009) J Psychiatry Neurosci , vol.34 , Issue.6 , pp. 433-442
    • Honer, W.G.1    Procyshyn, R.M.2    Chen, E.Y.3    MacEwan, G.W.4    Barr, A.M.5
  • 15
    • 4644271084 scopus 로고    scopus 로고
    • Magic shotguns versus magic bullets: Selectively non-selective drugs for mood disorders and schizophrenia
    • Roth BL, Sheffler DJ, Kroeze WK. Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat Rev Drug Discov. 2004;3(4):353-9. (Pubitemid 38499762)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.4 , pp. 353-359
    • Roth, B.L.1    Sheffer, D.J.2    Kroeze, W.K.3
  • 16
    • 11844286960 scopus 로고    scopus 로고
    • Mechanisms of action of second generation antipsychotic drugs in schizophrenia: Insights from brain imaging studies
    • DOI 10.1016/j.eurpsy.2004.11.003, PII S0924933804002676
    • Abi-Dargham A, Laruelle M. Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies. European Psychiatry. 2005;20(1):15-27. (Pubitemid 40092387)
    • (2005) European Psychiatry , vol.20 , Issue.1 , pp. 15-27
    • Abi-Dargham, A.1    Laruelle, M.2
  • 17
    • 54049141721 scopus 로고    scopus 로고
    • Antipsychotic drugs: Comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection
    • Lieberman JA, Bymaster FP, Meltzer HY, Deutch AY, Duncan GE, Marx CE, et al. Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection. Pharmacol Rev. 2008;60(3):358-403.
    • (2008) Pharmacol Rev , vol.60 , Issue.3 , pp. 358-403
    • Lieberman, J.A.1    Bymaster, F.P.2    Meltzer, H.Y.3    Deutch, A.Y.4    Duncan, G.E.5    Marx, C.E.6
  • 18
    • 56049085809 scopus 로고    scopus 로고
    • Schizophrenia "just the facts": What we know in 2008: Part 3: Neurobiology
    • Keshavan MS, Tandon R, Boutros NN, Nasrallah HA. Schizophrenia, "just the facts": what we know in 2008: Part 3: Neurobiology. Schizophr Res. 2008;106(2-3):89-107.
    • (2008) Schizophr Res , vol.106 , Issue.2-3 , pp. 89-107
    • Keshavan, M.S.1    Tandon, R.2    Boutros, N.N.3    Nasrallah, H.A.4
  • 19
    • 34247118744 scopus 로고    scopus 로고
    • Polypharmacy: When is it rational?
    • DOI 10.1097/01.pra.0000265766.25495.3b, PII 0013174620070300000006
    • Preskorn S, Lacey R. Polypharmacy: when is it rational? J Psychiatr Pract. 2007;13(2):97-105. (Pubitemid 46588311)
    • (2007) Journal of Psychiatric Practice , vol.13 , Issue.2 , pp. 97-105
    • Preskorn, S.H.1    Lacey, R.L.2
  • 20
    • 70449356886 scopus 로고    scopus 로고
    • Outcomes for schizophrenia patients with clozapine treatment: How good does it get?
    • Wheeler A, Humberstone V, Robinson G. Outcomes for schizophrenia patients with clozapine treatment: how good does it get? J Psychopharmacol. 2009;23(8):957-65.
    • (2009) J Psychopharmacol , vol.23 , Issue.8 , pp. 957-965
    • Wheeler, A.1    Humberstone, V.2    Robinson, G.3
  • 21
    • 0024443178 scopus 로고
    • A prospective study of clozapine in treatment-resistant schizophrenic patients. I. Preliminary report
    • Meltzer HY, Bastani B, Kwon KY, Ramirez LF, Burnett S, Sharpe J. A prospective study of clozapine in treatment-resistant schizophrenic patients. Psychopharmacology. 1989;99:S68-72. (Pubitemid 19244143)
    • (1989) Psychopharmacology , vol.99 , Issue.SUPPL.
    • Meltzer, H.Y.1    Bastani, B.2    Kwon, K.Y.3    Ramirez, L.F.4    Burnett, S.5    Sharpe, J.6
  • 22
    • 72849140996 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, placebo-controlled, 16-week study of adjunctive aripiprazole for schizophrenia or schizoaffective disorder inadequately treated with quetiapine or risperidone monotherapy
    • Kane J, Correll C, Goff D, Kirkpatrick B, Marder S, Vester- Blokland E, et al. A multicenter, randomized, double-blind, placebo-controlled, 16-week study of adjunctive aripiprazole for schizophrenia or schizoaffective disorder inadequately treated with quetiapine or risperidone monotherapy. J Clin Psychiatry. 2009;70 (10):1348-57.
    • (2009) J Clin Psychiatry , vol.70 , Issue.10 , pp. 1348-1357
    • Kane, J.1    Correll, C.2    Goff, D.3    Kirkpatrick, B.4    Marder, S.5    Vester- Blokland, E.6
  • 23
    • 65349112410 scopus 로고    scopus 로고
    • Antipsychotic combinations vs monotherapy in schizophrenia: A meta-analysis of randomized controlled trials
    • Correll C, Rummel-Kluge C, Corves C, Kane J, Leucht S. Antipsychotic combinations vs monotherapy in schizophrenia: a meta-analysis of randomized controlled trials. Schizophr Bull. 2009;35(2):443-57.
    • (2009) Schizophr Bull , vol.35 , Issue.2 , pp. 443-457
    • Correll, C.1    Rummel-Kluge, C.2    Corves, C.3    Kane, J.4    Leucht, S.5
  • 24
    • 1642534546 scopus 로고    scopus 로고
    • Sulpiride augmentation of olanzapine in the management of treatment-resistant chronic schizophrenia: Evidence for improvement of mood symptomatology
    • DOI 10.1097/00004850-200401000-00004
    • Kotler M, Strous RD, Reznik I, Shwartz S, Weizman A, Spivak B. Sulpiride augmentation of olanzapine in the management of treatment-resistant chronic schizophrenia: evidence for improvement of mood symptomatology. Int Clin Psychopharmacol. 2004;19(1):23-6. (Pubitemid 38114620)
    • (2004) International Clinical Psychopharmacology , vol.19 , Issue.1 , pp. 23-26
    • Kotler, M.1    Strous, R.D.2    Reznik, I.3    Shwartz, S.4    Weizman, A.5    Spivak, B.6
  • 25
    • 4444345535 scopus 로고    scopus 로고
    • Combined therapy with low-potency neuroleptic levomepromazine as an adjunct to haloperidol for agitated patients with acute exacerbation of schizophrenia
    • DOI 10.1016/j.eurpsy.2004.07.001, PII S0924933804001804
    • Higashima M, Takeda T, Nagasawa T, Hirao N, Oka T, Nakamura M, et al. Combined therapy with low-potency neuroleptic levomepromazine as an adjunct to haloperidol for agitated patients with acute exacerbation of schizophrenia. European Psychiatry. 2004;19 (6):380-1. (Pubitemid 39207968)
    • (2004) European Psychiatry , vol.19 , Issue.6 , pp. 380-381
    • Higashima, M.1    Takeda, T.2    Nagasawa, T.3    Hirao, N.4    Oka, T.5    Nakamura, M.6    Kitamura, M.7    Koshino, Y.8
  • 26
    • 0031791214 scopus 로고    scopus 로고
    • Imaging dopamine transmission in schizophrenia: A review and meta- analysis
    • Laruelle M. Imaging dopamine transmission in schizophrenia. A review and meta-analysis. Q J Nucl Med. 1998;42(3):211-21. (Pubitemid 28529874)
    • (1998) Quarterly Journal of Nuclear Medicine , vol.42 , Issue.3 , pp. 211-221
    • Laruelle, M.1
  • 27
    • 69249145260 scopus 로고    scopus 로고
    • Mechanisms underlying psychosis and antipsychotic treatment response in schizophrenia: Insights from PET and SPECT imaging
    • Howes O, Egerton A, Allan V, McGuire P, Stokes P, Kapur S. Mechanisms underlying psychosis and antipsychotic treatment response in schizophrenia: insights from PET and SPECT imaging. Curr Pharm Des. 2009;15(22):2550-9.
    • (2009) Curr Pharm des , vol.15 , Issue.22 , pp. 2550-2559
    • Howes, O.1    Egerton, A.2    Allan, V.3    McGuire, P.4    Stokes, P.5    Kapur, S.6
  • 28
    • 77953755155 scopus 로고    scopus 로고
    • Review: The biological basis of antipsychotic response in schizophrenia
    • Stone JM, Raffin M, Morrison P, McGuire PK. Review: the biological basis of antipsychotic response in schizophrenia. J Psychopharmacol. 2010;24(7):953-64.
    • (2010) J Psychopharmacol , vol.24 , Issue.7 , pp. 953-964
    • Stone, J.M.1    Raffin, M.2    Morrison, P.3    McGuire, P.K.4
  • 29
    • 0033979468 scopus 로고    scopus 로고
    • An atypical compound by any other name is still a
    • Meltzer HY. An atypical compound by any other name is still a. Psychopharmacology. 2000;148:16-9. (Pubitemid 30062466)
    • (2000) Psychopharmacology , vol.148 , Issue.1 , pp. 16-19
    • Meltzer, H.Y.1
  • 30
    • 79955429050 scopus 로고    scopus 로고
    • The Schizophrenia Consensus Group of the British Association for Psychopharmacology. Evidence-based guidelines for the pharmacological treatment of schizophrenia: Recommendations from the British Association for Psychopharmacology
    • Barnes TR, The Schizophrenia Consensus Group of the British Association for Psychopharmacology. Evidence-based guidelines for the pharmacological treatment of schizophrenia: recommendations from the British Association for Psychopharmacology. J Psychopharmacol. 2011;25(5):567-620.
    • (2011) J Psychopharmacol , vol.25 , Issue.5 , pp. 567-620
    • Barnes, T.R.1
  • 33
    • 70049104227 scopus 로고    scopus 로고
    • Clozapine combined with different antipsychotic drugs for treatment resistant schizophrenia
    • Cipriani A, Boso M, Barbui C. Clozapine combined with different antipsychotic drugs for treatment resistant schizophrenia. Cochrane Database Syst Rev. 2009(3).
    • (2009) Cochrane Database Syst Rev , Issue.3
    • Cipriani, A.1    Boso, M.2    Barbui, C.3
  • 34
    • 34247846196 scopus 로고    scopus 로고
    • Comparison of clozapine-amisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: A single-blind randomized study
    • Genc Y, Taner E, Candansayar S. Comparison of clozapineamisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: a single-blind randomized study. Adv Ther. 2007;24(1):1-13. (Pubitemid 46700860)
    • (2007) Advances in Therapy , vol.24 , Issue.1 , pp. 1-13
    • Genc, Y.1    Taner, E.2    Candansayar, S.3
  • 35
    • 65349177685 scopus 로고    scopus 로고
    • Efficacy and tolerability of ziprasidone versus risperidone as augmentation in patients partially responsive to clozapine: A randomised controlled clinical trial
    • Zink M, Kuwilsky A, Krumm B, Dressing H. Efficacy and tolerability of ziprasidone versus risperidone as augmentation in patients partially responsive to clozapine: a randomised controlled clinical trial. J Psychopharmacol. 2009;23(3):305-14.
    • (2009) J Psychopharmacol , vol.23 , Issue.3 , pp. 305-314
    • Zink, M.1    Kuwilsky, A.2    Krumm, B.3    Dressing, H.4
  • 36
    • 70049118581 scopus 로고    scopus 로고
    • Sulpiride clozapine combined high and low doses observed in the treatment of schizophrenia
    • Kong Q. Sulpiride clozapine combined high and low doses observed in the treatment of schizophrenia. Shandong Archives of Psychiatry. 2001;14:138-9.
    • (2001) Shandong Archives of Psychiatry , vol.14 , pp. 138-139
    • Kong, Q.1
  • 37
    • 65349163482 scopus 로고    scopus 로고
    • Does the addition of a second antipsychotic drug improve clozapine treatment?
    • Barbui C, Signoretti A, Mulè S, Boso M, Cipriani A. Does the addition of a second antipsychotic drug improve clozapine treatment? Schizophr Bull. 2009;35(2):458-68.
    • (2009) Schizophr Bull , vol.35 , Issue.2 , pp. 458-468
    • Barbui, C.1    Signoretti, A.2    Mulè, S.3    Boso, M.4    Cipriani, A.5
  • 38
    • 65749098355 scopus 로고    scopus 로고
    • Augmentation of clozapine with a second antipsychotic - A meta-analysis of randomized, placebo-controlled studies
    • Taylor DM, Smith L. Augmentation of clozapine with a second antipsychotic - a meta-analysis of randomized, placebo-controlled studies. Acta Psychiatr Scand. 2009;119(6):419-25.
    • (2009) Acta Psychiatr Scand , vol.119 , Issue.6 , pp. 419-425
    • Taylor, D.M.1    Smith, L.2
  • 39
    • 79955619123 scopus 로고    scopus 로고
    • Aripiprazole versus haloperidol in combination with clozapine for treatment-resistant schizophrenia in routine clinical care: A randomized, controlled trial
    • Barbui C, Accordini S, Nose M, Stroup S, Purgato M, Girlanda F, et al. Aripiprazole versus haloperidol in combination with clozapine for treatment-resistant schizophrenia in routine clinical care: a randomized, controlled trial. J Clin Psychopharmacol. 2011;31 (3):266-73.
    • (2011) J Clin Psychopharmacol , vol.31 , Issue.3 , pp. 266-273
    • Barbui, C.1    Accordini, S.2    Nose, M.3    Stroup, S.4    Purgato, M.5    Girlanda, F.6
  • 40
    • 79952360373 scopus 로고    scopus 로고
    • Effect of aripiprazole augmentation of clozapine in schizophrenia: A double-blind, placebo-controlled study
    • Muscatello MRA, Bruno A, Pandolfo G, Micò U, Scimeca G, Di Nardo F, et al. Effect of aripiprazole augmentation of clozapine in schizophrenia: a double-blind, placebo-controlled study. Schizophr Res. 2011;127(1-3):93-9.
    • (2011) Schizophr Res , vol.127 , Issue.1-3 , pp. 93-99
    • Muscatello, M.R.A.1    Bruno, A.2    Pandolfo, G.3    Micò, U.4    Scimeca, G.5    Di Nardo, F.6
  • 41
    • 77957230409 scopus 로고    scopus 로고
    • Effects of adjunctive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: A randomized, doubleblind, placebo-controlled trial
    • Fleischhacker WW, Heikkinen ME, Olié J-P, Landsberg W, Dewaele P, McQuade RD, et al. Effects of adjunctive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: a randomized, doubleblind, placebo-controlled trial. Int J Neuropsychopharmacol. 2010;13(08):1115-25.
    • (2010) Int J Neuropsychopharmacol , vol.13 , Issue.8 , pp. 1115-1125
    • Fleischhacker, W.W.1    Heikkinen, M.E.2    Olié, J.-P.3    Landsberg, W.4    Dewaele, P.5    McQuade, R.D.6
  • 42
    • 45249113944 scopus 로고    scopus 로고
    • Aripiprazole augmentation in clozapine-treated patients with refractory schizophrenia: An 8-week, randomized, double-blind, placebo-controlled trial
    • Chang J, Ahn Y, Park H, Lee K, Kim S, Kang U, et al. Aripiprazole augmentation in clozapine-treated patients with refractory schizophrenia: an 8-week, randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2008;69(5):720-31. (Pubitemid 351838681)
    • (2008) Journal of Clinical Psychiatry , vol.69 , Issue.5 , pp. 720-731
    • Chang, J.S.1    Ahn, Y.M.2    Park, H.J.3    Lee, K.Y.4    Kim, S.H.5    Kang, U.G.6    Kim, Y.S.7
  • 46
    • 6344253360 scopus 로고    scopus 로고
    • Antipsychotic-induced hyperprolactinaemia: Mechanisms, clinical features and management
    • DOI 10.2165/00003495-200464200-00003
    • Haddad PM, Wieck A. Antipsychotic-induced hyperprolactinaemia: mechanisms, clinical features and management. Drugs. 2004;64(20):2291-314. (Pubitemid 39388605)
    • (2004) Drugs , vol.64 , Issue.20 , pp. 2291-2314
    • Haddad, P.M.1    Wieck, A.2
  • 48
    • 0030430029 scopus 로고    scopus 로고
    • Effects of the novel antipsychotic agent 7-(4-[4-(2,3-dichlorophenyl)-1- piperazinyl] butyloxy)-3,4-dihydro -2(1H)-quinolinone (OPC-14597) on prolactin release from the rat anterior pituitary gland
    • Inoue T, Domae M, Yamada K, Furukawa T. Effects of the novel antipsychotic agent 7-(4-[4-(2,3-dichlorophenyl)-1-piperazinyl] butyloxy)-3,4-dihydro -2(1H)-quinolinone (OPC-14597) on prolactin release from the rat anterior pituitary gland. J Pharmacol Exp Ther. 1996;277(1):137-43.
    • (1996) J Pharmacol Exp Ther , vol.277 , Issue.1 , pp. 137-143
    • Inoue, T.1    Domae, M.2    Yamada, K.3    Furukawa, T.4
  • 49
    • 79961166634 scopus 로고    scopus 로고
    • Comparative pharmacology of antipsychotics possessing combined dopamine D2 and serotonin 5- HT1A receptor properties
    • Newman-Tancredi A, Kleven M. Comparative pharmacology of antipsychotics possessing combined dopamine D2 and serotonin 5- HT1A receptor properties. Psychopharmacology. 2011;216(4):451-73.
    • (2011) Psychopharmacology , vol.216 , Issue.4 , pp. 451-473
    • Newman-Tancredi, A.1    Kleven, M.2
  • 50
    • 0027489189 scopus 로고
    • Partial dopamine receptor agonists reverse behavioral, biochemical and neuroendocrine effects of neuroleptics in the rat: Potential treatment of extrapyramidal side effects
    • DOI 10.1016/0028-3908(93)90069-F
    • Svensson K, Eriksson E, Carlsson A. Partial dopamine receptor agonists reverse behavioral, biochemical and neuroendocrine effects of neuroleptics in the rat: potential treatment of extrapyramidal side effects. Neuropharmacology. 1993;32(10):1037-45. (Pubitemid 23316511)
    • (1993) Neuropharmacology , vol.32 , Issue.10 , pp. 1037-1045
    • Svensson, K.1    Eriksson, E.2    Carlsson, A.3
  • 51
    • 69249142661 scopus 로고    scopus 로고
    • Evidence for the partial dopaminereceptor agonist aripiprazole as a first-line treatment of psychosis in patients with iatrogenic or tumorogenic hyperprolactinemia
    • Hoffer Z, Roth R, Mathews M. Evidence for the partial dopaminereceptor agonist aripiprazole as a first-line treatment of psychosis in patients with iatrogenic or tumorogenic hyperprolactinemia. Psychosomatics. 2009;50:317-24.
    • (2009) Psychosomatics , vol.50 , pp. 317-324
    • Hoffer, Z.1    Roth, R.2    Mathews, M.3
  • 52
    • 34648833682 scopus 로고    scopus 로고
    • Adjunctive treatment with a dopamine partial agonist, aripiprazole, for antipsychotic-induced hyperprolactinemia: A placebo-controlled trial
    • DOI 10.1176/appi.ajp.2007.06071075
    • Shim J, Shin J, Kelly D, Jung D, Seo Y, Liu K, et al. Adjunctive treatment with a dopamine partial agonist, aripiprazole, for antipsychotic-induced hyperprolactinemia: a placebo-controlled trial. Am J Psychiatry. 2007;164(9):1404-10. (Pubitemid 47461141)
    • (2007) American Journal of Psychiatry , vol.164 , Issue.9 , pp. 1404-1410
    • Shim, J.-C.1    Shin, J.-G.K.2    Kelly, D.L.3    Jung, D.-U.4    Seo, Y.-S.5    Liu, K.-H.6    Shon, J.-H.7    Conley, R.R.8
  • 53
    • 78651293256 scopus 로고    scopus 로고
    • Preliminary report: A naturalistic study of the effect of aripiprazole addition on risperidonerelated hyperprolactinemia in patients treated with risperidone long-acting injection
    • van Kooten M, Arends J, Cohen D. Preliminary report: a naturalistic study of the effect of aripiprazole addition on risperidonerelated hyperprolactinemia in patients treated with risperidone long-acting injection. J Clin Psychopharmacol. 2011;31(1):126-8.
    • (2011) J Clin Psychopharmacol , vol.31 , Issue.1 , pp. 126-128
    • Van Kooten, M.1    Arends, J.2    Cohen, D.3
  • 54
    • 79960684945 scopus 로고    scopus 로고
    • Is antipsychotic polypharmacy associated with metabolic syndrome even after adjustment for lifestyle effects?: A crosssectional study
    • Misawa F, Shimizu K, Fujii Y, Miyata R, Koshiishi F, Kobayashi M, et al. Is antipsychotic polypharmacy associated with metabolic syndrome even after adjustment for lifestyle effects?: a crosssectional study. BMC Psychiatry. 2011;11(1):118.
    • (2011) BMC Psychiatry , vol.11 , Issue.1 , pp. 118
    • Misawa, F.1    Shimizu, K.2    Fujii, Y.3    Miyata, R.4    Koshiishi, F.5    Kobayashi, M.6
  • 55
    • 33845320133 scopus 로고    scopus 로고
    • Does antipsychotic polypharmacy increase the risk for metabolic syndrome?
    • DOI 10.1016/j.schres.2006.08.017, PII S0920996406003641
    • Correll CU, Frederickson AM, Kane JM, Manu P. Does antipsychotic polypharmacy increase the risk for metabolic syndrome? Schizophr Res. 2007;89(1-3):91-100. (Pubitemid 44881290)
    • (2007) Schizophrenia Research , vol.89 , Issue.1-3 , pp. 91-100
    • Correll, C.U.1    Frederickson, A.M.2    Kane, J.M.3    Manu, P.4
  • 56
    • 79957804999 scopus 로고    scopus 로고
    • The use of first generation versus second generation antipsychotics as addon or as switch treatment and its effect on QTC interval: The Italian experience in a real-world setting
    • Di Sciascio G, Calo S, Amodio G, D'Onofrio S, Pollice R. The use of first generation versus second generation antipsychotics as addon or as switch treatment and its effect on QTC interval: the Italian experience in a real-world setting. Int J Immunopathol Pharmacol. 2011;24(1):225-30.
    • (2011) Int J Immunopathol Pharmacol , vol.24 , Issue.1 , pp. 225-230
    • Di Sciascio, G.1    Calo, S.2    Amodio, G.3    D'Onofrio, S.4    Pollice, R.5
  • 58
    • 77649122136 scopus 로고    scopus 로고
    • Antipsychotic polypharmacy and risk of death from natural causes in patients with schizophrenia: A population-based nested case-control study
    • Baandrup L, Gasse C, Jensen V, Glenthoj B, Nordentoft M, Lublin H, et al. Antipsychotic polypharmacy and risk of death from natural causes in patients with schizophrenia: a population-based nested case-control study. J Clin Psychiatry. 2010;1(2):103-8.
    • (2010) J Clin Psychiatry , vol.1 , Issue.2 , pp. 103-108
    • Baandrup, L.1    Gasse, C.2    Jensen, V.3    Glenthoj, B.4    Nordentoft, M.5    Lublin, H.6
  • 59
    • 68949172254 scopus 로고    scopus 로고
    • 11-year follow-up of mortality in patients with schizophrenia: A population-based cohort study (FIN11 study)
    • Tiihonen J, Lönnqvist J, Wahlbeck K, Klaukka T, Niskanen L, Tanskanen A, et al. 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study). Lancet. 2009;374(9690):620-7.
    • (2009) Lancet , vol.374 , Issue.9690 , pp. 620-627
    • Tiihonen, J.1    Lönnqvist, J.2    Wahlbeck, K.3    Klaukka, T.4    Niskanen, L.5    Tanskanen, A.6
  • 61
  • 62
    • 79960528578 scopus 로고    scopus 로고
    • When is polypharmacy an advantage?
    • Tamminga C. When is polypharmacy an advantage? Am J Psychiatry. 2011;168(7):663.
    • (2011) Am J Psychiatry , vol.168 , Issue.7 , pp. 663
    • Tamminga, C.1
  • 63
    • 58249085773 scopus 로고    scopus 로고
    • Effects of aripiprazole on prolactin levels in subjects with schizophrenia during cross-titration with risperidone or olanzapine: Analysis of a randomized, open-label study
    • Byerly MJ, Marcus RN, Tran Q-V, Eudicone JM, Whitehead R, Baker RA. Effects of aripiprazole on prolactin levels in subjects with schizophrenia during cross-titration with risperidone or olanzapine: analysis of a randomized, open-label study. Schizophr Res. 2009;107(2-3):218-22.
    • (2009) Schizophr Res , vol.107 , Issue.2-3 , pp. 218-222
    • Byerly, M.J.1    Marcus, R.N.2    Tran, Q.-V.3    Eudicone, J.M.4    Whitehead, R.5    Baker, R.A.6
  • 65
    • 65249107131 scopus 로고    scopus 로고
    • Schizophrenia from a neural circuitry perspective: Advancing toward rational pharmacological therapies
    • Lewis DA, Sweet RA. Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapies. J Clin Invest. 2009;119(4):706-16.
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 706-716
    • Lewis, D.A.1    Sweet, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.